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The map label for this gene is resE [H]

Identifier: 218901846

GI number: 218901846

Start: 680713

End: 682098

Strand: Reverse

Name: resE [H]

Synonym: BCAH820_0707

Alternate gene names: 218901846

Gene position: 682098-680713 (Counterclockwise)

Preceding gene: 218901847

Following gene: 218901844

Centisome position: 12.86

GC content: 34.27

Gene sequence:

>1386_bases
ATGAAACGAATTTCTATTCAGCTCGGATTTTATTTTTTAATTGTTACACTTTTAATCGAAAGTGTTCTATTTGTTTTGCT
TTATTATAGCCTTGTCAACAATAGAGTAAATGAAGAAATGACAGCTTTATTAAAGCGCGGAAATAGTCACAGAGATGTCC
TTGAAAAGTATTTTGATAAGCAAACAATCTCCCATGTTGCGCTAATGGAATCCGAAGCCGAAACGACTGTTGTTATTACA
AATGCAAATAAGGATGTACTAGCCAAATCCAACGAAATAAATACTACTATAAAAAAGCATATTGAAAAGATGCAAACACG
GACAGATCATGAAGGTGCAATTATAGAGAATCATTGGAAAACATCTAATTATATATGTACAGTTAGTCCCATTGTAGTAG
ATGGAAAACATGAAGGCTATGTGTACATGTTTCTTGGGACAGAATCTATTGAAAAAATGGTGAATGGGCTAACAATACAA
TTCATTATTGCCGGAGTCATTACGTTTCTATTAACAGCCATTACCATCTTTCTCTTATCACGGTTGTTAACAAAACCATT
GTTACACATGAAACATGCCACTGAAAAAATGAGTAAAGGTGATTTATCAGTTTCGTTAACGACTACTCGAAATGATGAAA
TTGGTGAACTAGCATCGTCTATTCAAACGCTTGCTAATGATTTACATTATATGAAAACAGAGCGAAGTGAATTTCTAGCA
AGTGTTGCTCACGAATTACGAACACCATTAACGTACGTAAGAGGTTACGCTGATATTGCTTTAAAAGAAAGCACATCTCC
TGAGCAACGTTTGCGATATTTATCTATTATAAAAGATGAGTCTGATTACATTACAAACTTAGTTCAAGATTTATTTTCAC
TTGCACAAATGGAACAACATAACTTTTCTATTCAAGTAAAGGAAGTACATTTACACACTTTCCTTACTCGCATATCTGAA
AAAGTAAACGCCATGTATAAAGAAAGATACATTACAGTTTCTTTCTCTTGTCCTCCTACACTGCTAGTAAACTTAGATGA
ACAACGATTTGAACAAGTTGTAGTGAACATTTTAAATAACGCTTATAGACATTCAAAAGAACATTCTCAAATTCATATTT
CTGTTATAGAAGAAAATAAACGTATCTCCATTACAATGGAAGATGAAGGCGAAGGTATTCCTCCTGAAGACCTCCCTCAC
ATTTTCGAACGCTTTTATCGAGTTGATAAAGCTAGATCACGAGCTACCGGTGGGACTGGTTTAGGGCTATCTATCGTGAA
AGAAATTGTAGAACTACACGGCGGAAATATTACTGTAACGAGCGAAGTTGATCACGGGTCTTGTTTTACAATTTCATTGC
CATCTATAAAGAAACACGACTATTGA

Upstream 100 bases:

>100_bases
ATAAATTACGAAAAGTAAATTTCCCTATTGATAATCATTTAAAAACTGTGTACGGAGTTGGTTATCGATGGATTGATATC
GAACATTAAGGAGCAAAACG

Downstream 100 bases:

>100_bases
TGGTAGTCGTGTTTCTTTATCATTTTACTTTATAATATAAGTTTACAAATTGCCCAAAACGTTTCGTATCCGTTAAAGTT
AAATGGATTTCTGGGTTCTT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDKQTISHVALMESEAETTVVIT
NANKDVLAKSNEINTTIKKHIEKMQTRTDHEGAIIENHWKTSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTIQ
FIIAGVITFLLTAITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKESTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISE
KVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPH
IFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDY

Sequences:

>Translated_461_residues
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDKQTISHVALMESEAETTVVIT
NANKDVLAKSNEINTTIKKHIEKMQTRTDHEGAIIENHWKTSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTIQ
FIIAGVITFLLTAITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKESTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISE
KVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPH
IFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDY
>Mature_461_residues
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDKQTISHVALMESEAETTVVIT
NANKDVLAKSNEINTTIKKHIEKMQTRTDHEGAIIENHWKTSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTIQ
FIIAGVITFLLTAITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKESTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISE
KVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPH
IFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDY

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=277, Percent_Identity=31.7689530685921, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=32.046332046332, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786783, Length=348, Percent_Identity=27.8735632183908, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1787894, Length=286, Percent_Identity=27.2727272727273, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1790346, Length=338, Percent_Identity=28.9940828402367, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=30.4347826086957, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=29.2035398230088, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=27.8008298755187, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=29.957805907173, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=30.5555555555556, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788279, Length=311, Percent_Identity=27.6527331189711, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081816, Length=336, Percent_Identity=25.297619047619, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789149, Length=222, Percent_Identity=29.2792792792793, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082128, Length=308, Percent_Identity=24.3506493506494, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790861, Length=256, Percent_Identity=27.734375, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=30.2222222222222, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789808, Length=293, Percent_Identity=27.9863481228669, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789403, Length=327, Percent_Identity=27.217125382263, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790551, Length=281, Percent_Identity=28.1138790035587, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=29.5275590551181, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787374, Length=243, Percent_Identity=26.3374485596708, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52541; Mature: 52541

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDK
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHH
QTISHVALMESEAETTVVITNANKDVLAKSNEINTTIKKHIEKMQTRTDHEGAIIENHWK
HHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCC
TSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTIQFIIAGVITFLLTAITIFLLS
CCCEEEEEEEEEEECCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAHELRTPLTYVRGYADIALKESTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQH
HHHHHHHCCHHHHCCHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
NFSIQVKEVHLHTFLTRISEKVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
AYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPHIFERFYRVDKARSRATGGTG
HHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
LGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDY
CCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDK
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHH
QTISHVALMESEAETTVVITNANKDVLAKSNEINTTIKKHIEKMQTRTDHEGAIIENHWK
HHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCC
TSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTIQFIIAGVITFLLTAITIFLLS
CCCEEEEEEEEEEECCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAHELRTPLTYVRGYADIALKESTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQH
HHHHHHHCCHHHHCCHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
NFSIQVKEVHLHTFLTRISEKVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
AYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPHIFERFYRVDKARSRATGGTG
HHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
LGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDY
CCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]