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The map label for this gene is fecD [C]

Identifier: 218884758

GI number: 218884758

Start: 1341120

End: 1342058

Strand: Reverse

Name: fecD [C]

Synonym: DKAM_1447

Alternate gene names: 218884758

Gene position: 1342058-1341120 (Counterclockwise)

Preceding gene: 218884759

Following gene: 218884757

Centisome position: 98.3

GC content: 42.81

Gene sequence:

>939_bases
ATGAAGCAAAGAGATCTCTGGCTTCTAGGCCTACTACTTGTTTTTTCCATAATGCTAATATACGATCTCAACGATGTTCA
ACACAATTCATTATTATTTAACTATAGATTAAGCAGGATTCTCTCAGTGATTTCAACTGGCATAATTATAGGTTTAACCG
GAGTATATCTTCAGTCCTCACTACGTAATCCACTAGTAGACCACTACATACTCGGGATAGGAAGCGGCTCACTTGTGTTT
ACTTATCTAAGTATTTTAATAGCTGGAGGCTTCACTCTCGCTACCCCATTGTCCTCGATGCTTGGCGGGCTTTTAGCCTT
ATTTCTCACAATCATACTGGCGGAGAAGTTATCTGGCACAGCTACTTCATATGTGCTAGCCGGCATTGGCGTTAACTCTT
TTTTCTCAGGCATATCGACTCTCCTATCTTATCTAACGATCCGTGTTTACCCGTATGCGCAGCTTCTTCTCGTTGGAAGC
TTCATAGTTGCCACCAATGATAAGTTATATATGTTATCTATTCCCCTAGTCATCTCAGCATCCATGATGCTCATTCTTGC
AAAGCCCCTTAACACGCTGGAGGTAAGCGATGAATTCTCAGTAATAACCGGGTTTAACCCCCGAGTTATACGCTTGATCT
CAATAATTGTCGCCGGTTTAACCAGCAGTATCGTCACCTCACTCTACGGTTTAATAGGTTTTATTGGATTGGCATCACCA
CATATAGCGAGGTACCTATCTGGTAGGAGTGATAACAGGGTTGTCGCGCCTTTAGCGGCCTTCACATCATCTATAATACT
TTATGTAACCGACTTTACAAGCAGGAGGCTCTTCGCTGTAATATGGAGTGAAATACCGGCTGGAGCCATCGCCTCACTTA
TTGGGGCTCCGTTCTTCATATATTTACTGCTCTCGAGGCGGAGGATATATGGTGATTAA

Upstream 100 bases:

>100_bases
GTAGTGAAGGGTCATCAACATACTCAGTCATGGCGATCATTGTACTCGTCGCTTCAGTAGCGTTGATTACCATGGTGCTT
GCAAAGAGGTATTGGAGGAA

Downstream 100 bases:

>100_bases
GGCCAGTAATGTAGTAGTCGAATATACAGGTGGATTAAAGGGATTAAACAATGCATCTCTCGAAATAATGGAGAATAAAG
TCACATGCTTAATGGGTCCT

Product: Iron compound ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKQRDLWLLGLLLVFSIMLIYDLNDVQHNSLLFNYRLSRILSVISTGIIIGLTGVYLQSSLRNPLVDHYILGIGSGSLVF
TYLSILIAGGFTLATPLSSMLGGLLALFLTIILAEKLSGTATSYVLAGIGVNSFFSGISTLLSYLTIRVYPYAQLLLVGS
FIVATNDKLYMLSIPLVISASMMLILAKPLNTLEVSDEFSVITGFNPRVIRLISIIVAGLTSSIVTSLYGLIGFIGLASP
HIARYLSGRSDNRVVAPLAAFTSSIILYVTDFTSRRLFAVIWSEIPAGAIASLIGAPFFIYLLLSRRRIYGD

Sequences:

>Translated_312_residues
MKQRDLWLLGLLLVFSIMLIYDLNDVQHNSLLFNYRLSRILSVISTGIIIGLTGVYLQSSLRNPLVDHYILGIGSGSLVF
TYLSILIAGGFTLATPLSSMLGGLLALFLTIILAEKLSGTATSYVLAGIGVNSFFSGISTLLSYLTIRVYPYAQLLLVGS
FIVATNDKLYMLSIPLVISASMMLILAKPLNTLEVSDEFSVITGFNPRVIRLISIIVAGLTSSIVTSLYGLIGFIGLASP
HIARYLSGRSDNRVVAPLAAFTSSIILYVTDFTSRRLFAVIWSEIPAGAIASLIGAPFFIYLLLSRRRIYGD
>Mature_312_residues
MKQRDLWLLGLLLVFSIMLIYDLNDVQHNSLLFNYRLSRILSVISTGIIIGLTGVYLQSSLRNPLVDHYILGIGSGSLVF
TYLSILIAGGFTLATPLSSMLGGLLALFLTIILAEKLSGTATSYVLAGIGVNSFFSGISTLLSYLTIRVYPYAQLLLVGS
FIVATNDKLYMLSIPLVISASMMLILAKPLNTLEVSDEFSVITGFNPRVIRLISIIVAGLTSSIVTSLYGLIGFIGLASP
HIARYLSGRSDNRVVAPLAAFTSSIILYVTDFTSRRLFAVIWSEIPAGAIASLIGAPFFIYLLLSRRRIYGD

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=283, Percent_Identity=26.8551236749117, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786805, Length=285, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=27.5618374558304, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790741, Length=287, Percent_Identity=28.9198606271777, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788004, Length=283, Percent_Identity=28.2685512367491, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786804, Length=220, Percent_Identity=30.4545454545455, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33877; Mature: 33877

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRDLWLLGLLLVFSIMLIYDLNDVQHNSLLFNYRLSRILSVISTGIIIGLTGVYLQSS
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNPLVDHYILGIGSGSLVFTYLSILIAGGFTLATPLSSMLGGLLALFLTIILAEKLSGT
HCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ATSYVLAGIGVNSFFSGISTLLSYLTIRVYPYAQLLLVGSFIVATNDKLYMLSIPLVISA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECHHHHHH
SMMLILAKPLNTLEVSDEFSVITGFNPRVIRLISIIVAGLTSSIVTSLYGLIGFIGLASP
HHHHHHHCCCCCEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HIARYLSGRSDNRVVAPLAAFTSSIILYVTDFTSRRLFAVIWSEIPAGAIASLIGAPFFI
HHHHHHCCCCCCCEEHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
YLLLSRRRIYGD
HHHHHHHHHCCC
>Mature Secondary Structure
MKQRDLWLLGLLLVFSIMLIYDLNDVQHNSLLFNYRLSRILSVISTGIIIGLTGVYLQSS
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNPLVDHYILGIGSGSLVFTYLSILIAGGFTLATPLSSMLGGLLALFLTIILAEKLSGT
HCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ATSYVLAGIGVNSFFSGISTLLSYLTIRVYPYAQLLLVGSFIVATNDKLYMLSIPLVISA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECHHHHHH
SMMLILAKPLNTLEVSDEFSVITGFNPRVIRLISIIVAGLTSSIVTSLYGLIGFIGLASP
HHHHHHHCCCCCEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HIARYLSGRSDNRVVAPLAAFTSSIILYVTDFTSRRLFAVIWSEIPAGAIASLIGAPFFI
HHHHHHCCCCCCCEEHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
YLLLSRRRIYGD
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]