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The map label for this gene is apt [C]

Identifier: 218884538

GI number: 218884538

Start: 1147471

End: 1148280

Strand: Reverse

Name: apt [C]

Synonym: DKAM_1227

Alternate gene names: 218884538

Gene position: 1148280-1147471 (Counterclockwise)

Preceding gene: 218884541

Following gene: 218884537

Centisome position: 84.11

GC content: 44.32

Gene sequence:

>810_bases
ATGATTAGGATTAAAGGCAGCAGGGTGCTAGTTGTAAAGCGCCCCAGCGAGTCCGAAGTGAGGGCTTTCGCTGAAAAGCT
GATGGCAGCTCACTCGAAGAGTAAGGCCGATAGAACCAAGATGAGGCTTATGGCTAGTGAAGTACTTAGATTGCTCAAGC
CTAATTTATCTTACAAGGATCTATACGAGATAACCGGTATCCCTGAGTCCGTGCTCTGCAGGTATGTGAGGGGCTCTATA
ATCCCTGGCTTCGAGCAGGCAGCCTTCATACTCTCAAAGATATCTCTCTCAATAGACTTAAGCTACCTGCTCAGAGACCT
AGTGGAGAAAGAGAAGAGCCCTATAATAGACTTGCTAAGAGTCCTTAAAGACCCCTATGTGGCTAGATTGCTTTCCATAA
TATTGATCCTGGAGTTAACAGGTAAAGAAGTCACAAAGATCATAGCTACAGCCGAAGCAGTGCTCCCACTAGCCACAATG
CTTTCACTAGAGTTCAATGCACCAATAGTTCTAATCAAGAGGAAGAGTTATCCGGGTGTTCAATACTATAGTACTTCATT
TATGAAGAGCCCGAAAGATATAGAGACCCTCTATCTTGACAGGGATTTACTGAGTAGAAAGGATAAGCTATTGATATTAT
CCGACGTAGTGTACTCTGGTAGAACATTGGAGGCGGTATTGGAGCTGGTCTCCAAGTCGAGGGCTGAGATCACTGATGTA
ATAGTAGTACTTGGCTTAGGCGAGATTTGGAGGGAACGCCTAGAGGAGTATAATATAAAGGTACTTACGGTGATCCCATT
TACCATGTAA

Upstream 100 bases:

>100_bases
AGCTCTTAAAACCCTCTTCATCCCATTGAGTCATTATTATTTTTATATTCCTTATTTAAAGATAAATAACTAAGGCTTAT
TTAATCAGGAGAGGGCAGGT

Downstream 100 bases:

>100_bases
CCATGATATGGAGATTTAAATAGGGCATGCATCTTAAGCATCATTCCGTATCTAGGACTTAAAGAGGGAAAGACATAGTT
ATAAGCATGTATTAGATCAA

Product: phosphoribosyltransferase

Products: AMP; Diphosphate [C]

Alternate protein names: Adenine Phosphoribosyltransferase

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MIRIKGSRVLVVKRPSESEVRAFAEKLMAAHSKSKADRTKMRLMASEVLRLLKPNLSYKDLYEITGIPESVLCRYVRGSI
IPGFEQAAFILSKISLSIDLSYLLRDLVEKEKSPIIDLLRVLKDPYVARLLSIILILELTGKEVTKIIATAEAVLPLATM
LSLEFNAPIVLIKRKSYPGVQYYSTSFMKSPKDIETLYLDRDLLSRKDKLLILSDVVYSGRTLEAVLELVSKSRAEITDV
IVVLGLGEIWRERLEEYNIKVLTVIPFTM

Sequences:

>Translated_269_residues
MIRIKGSRVLVVKRPSESEVRAFAEKLMAAHSKSKADRTKMRLMASEVLRLLKPNLSYKDLYEITGIPESVLCRYVRGSI
IPGFEQAAFILSKISLSIDLSYLLRDLVEKEKSPIIDLLRVLKDPYVARLLSIILILELTGKEVTKIIATAEAVLPLATM
LSLEFNAPIVLIKRKSYPGVQYYSTSFMKSPKDIETLYLDRDLLSRKDKLLILSDVVYSGRTLEAVLELVSKSRAEITDV
IVVLGLGEIWRERLEEYNIKVLTVIPFTM
>Mature_269_residues
MIRIKGSRVLVVKRPSESEVRAFAEKLMAAHSKSKADRTKMRLMASEVLRLLKPNLSYKDLYEITGIPESVLCRYVRGSI
IPGFEQAAFILSKISLSIDLSYLLRDLVEKEKSPIIDLLRVLKDPYVARLLSIILILELTGKEVTKIIATAEAVLPLATM
LSLEFNAPIVLIKRKSYPGVQYYSTSFMKSPKDIETLYLDRDLLSRKDKLLILSDVVYSGRTLEAVLELVSKSRAEITDV
IVVLGLGEIWRERLEEYNIKVLTVIPFTM

Specific function: Catalyzes A Salvage Reaction Resulting In The Formation Of Amp, That Is Energically Less Costly Than De Novo Synthesis. [C]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.2.7 [C]

Molecular weight: Translated: 30491; Mature: 30491

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIKGSRVLVVKRPSESEVRAFAEKLMAAHSKSKADRTKMRLMASEVLRLLKPNLSYKD
CEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LYEITGIPESVLCRYVRGSIIPGFEQAAFILSKISLSIDLSYLLRDLVEKEKSPIIDLLR
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCHHHHHH
VLKDPYVARLLSIILILELTGKEVTKIIATAEAVLPLATMLSLEFNAPIVLIKRKSYPGV
HHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCC
QYYSTSFMKSPKDIETLYLDRDLLSRKDKLLILSDVVYSGRTLEAVLELVSKSRAEITDV
HHHHHHHHCCCCHHHHHEECHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHH
IVVLGLGEIWRERLEEYNIKVLTVIPFTM
HHHHCCHHHHHHHHHHCCEEEEEEECCCC
>Mature Secondary Structure
MIRIKGSRVLVVKRPSESEVRAFAEKLMAAHSKSKADRTKMRLMASEVLRLLKPNLSYKD
CEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LYEITGIPESVLCRYVRGSIIPGFEQAAFILSKISLSIDLSYLLRDLVEKEKSPIIDLLR
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCHHHHHH
VLKDPYVARLLSIILILELTGKEVTKIIATAEAVLPLATMLSLEFNAPIVLIKRKSYPGV
HHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCC
QYYSTSFMKSPKDIETLYLDRDLLSRKDKLLILSDVVYSGRTLEAVLELVSKSRAEITDV
HHHHHHHHCCCCHHHHHEECHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHH
IVVLGLGEIWRERLEEYNIKVLTVIPFTM
HHHHCCHHHHHHHHHHCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): 560 [C]

Specific activity: 14

Km value (mM): 0.125 {5-phospho-alpha-D-ribose} 0.02 {adenine}} [C]

Substrates: Adenine; 5-Phospho-alpha-D-ribose 1-diphosphate [C]

Specific reaction: Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate --> AMP + Diphosphate [C]

General reaction: Pentosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA