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The map label for this gene is rpl18p

Identifier: 218884467

GI number: 218884467

Start: 1084291

End: 1084881

Strand: Reverse

Name: rpl18p

Synonym: DKAM_1156

Alternate gene names: 218884467

Gene position: 1084881-1084291 (Counterclockwise)

Preceding gene: 218884468

Following gene: 218884466

Centisome position: 79.47

GC content: 48.22

Gene sequence:

>591_bases
ATGGCTAAGGGTCCCCGGTATAAGGTTCCAAGGAGAAGGAGAAGGGAGGGTAAGACTAATTACTACAAGAGATATAGAAT
GATTGTATCGGGACATCCCCGTTTCATTGTTAGGAAGACGTTGAACTATATATGGGTGCAGGTAGCCACGGCTAGGCCAG
AGGGGGATGTAATCATAGCTGCAGCCCACTCAAACGAGTTAAGGAAGAGATTCGGGTGGAAAGCAGGTACATGTAATACC
TCTGCAGCCTATTTAACAGGGTTGCTGGCTGCTTTAAGGGCCCTTGAGAAGGGGGTTGAATACGCTGTACCAGATATAGG
GTTACATAGACCCGTTAAAGGGGCATTAGTGTTTGCAGCTATAAAGGCAGCCAACGATGCCGGGCTCAAGGTGCCAATGG
GTGGGGAAGTAGCCCCCAGCGAGGAGAGAATCAGGGGCGAGCACATAGCATCATATGCTAAGATACTGAGGGAGAATGGA
TTGCTTGAGAAAAGGTTTTCAAGGTATCTAGCCAATGGTTTACAGCCAGAGGACCTCCCCTCGCACTTTGAAGAGGTTAA
AAACAAGATCTTGGAGGCTTATAAGAGGTGA

Upstream 100 bases:

>100_bases
GCTTGCTAAGGGAGGATACTTTAACTCTCTTTCATCTCTGAAGCTACACCTTAAGGAAAACAATATCTTAAAGGAGGTTA
AATAGAGGGGTTGGTGAGGC

Downstream 100 bases:

>100_bases
TAAGTGTGTCCGCGAGCGCGGTTGATAAAGCTGCCTTAGAGAAATGGGTTCCCAGGACACGTGTAGGAAAAATGGTTTTA
GAGGGTAAGATAACTAGTTT

Product: 50S ribosomal protein L18P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MAKGPRYKVPRRRRREGKTNYYKRYRMIVSGHPRFIVRKTLNYIWVQVATARPEGDVIIAAAHSNELRKRFGWKAGTCNT
SAAYLTGLLAALRALEKGVEYAVPDIGLHRPVKGALVFAAIKAANDAGLKVPMGGEVAPSEERIRGEHIASYAKILRENG
LLEKRFSRYLANGLQPEDLPSHFEEVKNKILEAYKR

Sequences:

>Translated_196_residues
MAKGPRYKVPRRRRREGKTNYYKRYRMIVSGHPRFIVRKTLNYIWVQVATARPEGDVIIAAAHSNELRKRFGWKAGTCNT
SAAYLTGLLAALRALEKGVEYAVPDIGLHRPVKGALVFAAIKAANDAGLKVPMGGEVAPSEERIRGEHIASYAKILRENG
LLEKRFSRYLANGLQPEDLPSHFEEVKNKILEAYKR
>Mature_195_residues
AKGPRYKVPRRRRREGKTNYYKRYRMIVSGHPRFIVRKTLNYIWVQVATARPEGDVIIAAAHSNELRKRFGWKAGTCNTS
AAYLTGLLAALRALEKGVEYAVPDIGLHRPVKGALVFAAIKAANDAGLKVPMGGEVAPSEERIRGEHIASYAKILRENGL
LEKRFSRYLANGLQPEDLPSHFEEVKNKILEAYKR

Specific function: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance

COG id: COG0256

COG function: function code J; Ribosomal protein L18

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L18P family

Homologues:

Organism=Homo sapiens, GI14591909, Length=236, Percent_Identity=35.1694915254237, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17534333, Length=233, Percent_Identity=35.6223175965665, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6325126, Length=229, Percent_Identity=34.4978165938865, Blast_Score=101, Evalue=9e-23,
Organism=Drosophila melanogaster, GI116007384, Length=234, Percent_Identity=35.042735042735, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI116007382, Length=234, Percent_Identity=35.042735042735, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL18_DESK1 (B8D5V1)

Other databases:

- EMBL:   CP001140
- RefSeq:   YP_002428849.1
- GeneID:   7171245
- GenomeReviews:   CP001140_GR
- KEGG:   dka:DKAM_1156
- HOGENOM:   HBG391676
- OMA:   SRVYAAL
- ProtClustDB:   PRK08569
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_01337_A
- InterPro:   IPR005484
- InterPro:   IPR005485
- PANTHER:   PTHR23410

Pfam domain/function: PF00861 Ribosomal_L18p

EC number: NA

Molecular weight: Translated: 22101; Mature: 21970

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGPRYKVPRRRRREGKTNYYKRYRMIVSGHPRFIVRKTLNYIWVQVATARPEGDVIIA
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCCCEEEE
AAHSNELRKRFGWKAGTCNTSAAYLTGLLAALRALEKGVEYAVPDIGLHRPVKGALVFAA
ECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHH
IKAANDAGLKVPMGGEVAPSEERIRGEHIASYAKILRENGLLEKRFSRYLANGLQPEDLP
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHH
SHFEEVKNKILEAYKR
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKGPRYKVPRRRRREGKTNYYKRYRMIVSGHPRFIVRKTLNYIWVQVATARPEGDVIIA
CCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCCCEEEE
AAHSNELRKRFGWKAGTCNTSAAYLTGLLAALRALEKGVEYAVPDIGLHRPVKGALVFAA
ECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHH
IKAANDAGLKVPMGGEVAPSEERIRGEHIASYAKILRENGLLEKRFSRYLANGLQPEDLP
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHH
SHFEEVKNKILEAYKR
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA