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The map label for this gene is yleA [C]

Identifier: 218884393

GI number: 218884393

Start: 1023040

End: 1024338

Strand: Reverse

Name: yleA [C]

Synonym: DKAM_1082

Alternate gene names: 218884393

Gene position: 1024338-1023040 (Counterclockwise)

Preceding gene: 218884400

Following gene: 218884391

Centisome position: 75.03

GC content: 44.03

Gene sequence:

>1299_bases
ATGAGGGTGTATATTGAGACCTATGGATGTGCCCTGAATAAGAGCGATGAAGCATTGATGGTGGAGAATATTCTGCGCGA
GGGACATGAATTAGTTAACAGTATCGAAGATGCTGATACCCTTATAATCAATACATGTATTGTGAGACTGGATACAGAAT
ACCACATGGTTAAAAGGATAAGGGAGCTGTATGAAGTAGCTAGTAGAACAGGTAAGAAGCTAATTGTAGCCGGATGTATG
GCCAAGGCCGAACCATACACGGTGTTAAAGATAGCGCCTGAGGCCAGCCTTGTTTCGCCCCAGAATTCTGCCTTGATCAC
AGAAGTCTTGAAGACGCGGGGTAAGGTTATATTGATTGATGGATTAAGGGAAAGAGATAGAATAGGAATTCATGTAGAAG
ATAGGATCGCCCCGATACCAATACAGGAGGGCTGTCTAAGCAATTGCAGCTTTTGTATAACCAAGCATGCTAGACGCATC
CTCGTCAGCCATGGTATCGATGCTGTTGTAAAAGCAGTGGAGAGAGCAGTTAGAAACGGGGCAGTAGAGATACAGTTGAC
GGGTATGGATCTAGGTACATATGGCTTGGACCTCTATAAGACACGGAAGCTTCCGGAGCTGGTTAAGGAGGTGAGTAGAA
GAGTCAGTGGTGAATACATGATTAGAATAGGTATGATAAACCCGGAGCACTTACGCTACATCCTCGATGATTTAATAGAT
GCTATCAATGAATCCAGCAAGGTATATAGGTTCCTCCACATACCTCTGCAATCAGGAAGCAATAAAGTACTTAGTGTAAT
GCGCCGCAACTATAGCGTGGAGGAGTATATCGAGATAGTTAATGAGGCTAAATCAAGGATACCTGGTGTAAGTATTGCAA
CCGACATCATCGTTGGACATCCCATGGAGGATGAGGAAGACTTCAACGAGACCCTTAAAGTTATAAGGGAACTAGAGTTT
GAAAGAGTTCACTTGGCAGGTTATAGTATAAGACCGCTGACTTATTCAGCGTCACTACCCCAGGTACCAACCAGAGTTAA
GAAGGAAAGGGTTCTAAGGGCCCTACAGGTCATAGAAGAGGTTGGCTTGAAAATACGTTTAAAATACGTTGGAAAAGAAG
TGGAATGTTTCACCACGGAGCATTCGAATACATGGATTTGCAGGCTTGAAAACTATATCCCGGTAGTGGTAACAGGTAAG
AGCGGAGACCCCGCTCTAGATTATGGTAGATGGATCAGGGTGCTCGTAGACAATGCTACATTTTTCGATCTAAGGGGGAG
ATTCCTGGAGAGTAAGTAG

Upstream 100 bases:

>100_bases
GCTCCATGGATGATATAATAGGGTTATATATATGTAATCTTATGAAGAAGCAGGATATCAGGTATCTTTACGCCGGGGAT
GGCTGGAAACGGGTGCTGAT

Downstream 100 bases:

>100_bases
TACTCTACAAAGCTGTGAACGGAGACACTCTACTCCTTTAAAGCAGTTAATCGCTCATCACGTTGATACCGCTGGCTTTA
CCCTCAAGGGTCTTGGAGAG

Product: MiaB family RNA modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRVYIETYGCALNKSDEALMVENILREGHELVNSIEDADTLIINTCIVRLDTEYHMVKRIRELYEVASRTGKKLIVAGCM
AKAEPYTVLKIAPEASLVSPQNSALITEVLKTRGKVILIDGLRERDRIGIHVEDRIAPIPIQEGCLSNCSFCITKHARRI
LVSHGIDAVVKAVERAVRNGAVEIQLTGMDLGTYGLDLYKTRKLPELVKEVSRRVSGEYMIRIGMINPEHLRYILDDLID
AINESSKVYRFLHIPLQSGSNKVLSVMRRNYSVEEYIEIVNEAKSRIPGVSIATDIIVGHPMEDEEDFNETLKVIRELEF
ERVHLAGYSIRPLTYSASLPQVPTRVKKERVLRALQVIEEVGLKIRLKYVGKEVECFTTEHSNTWICRLENYIPVVVTGK
SGDPALDYGRWIRVLVDNATFFDLRGRFLESK

Sequences:

>Translated_432_residues
MRVYIETYGCALNKSDEALMVENILREGHELVNSIEDADTLIINTCIVRLDTEYHMVKRIRELYEVASRTGKKLIVAGCM
AKAEPYTVLKIAPEASLVSPQNSALITEVLKTRGKVILIDGLRERDRIGIHVEDRIAPIPIQEGCLSNCSFCITKHARRI
LVSHGIDAVVKAVERAVRNGAVEIQLTGMDLGTYGLDLYKTRKLPELVKEVSRRVSGEYMIRIGMINPEHLRYILDDLID
AINESSKVYRFLHIPLQSGSNKVLSVMRRNYSVEEYIEIVNEAKSRIPGVSIATDIIVGHPMEDEEDFNETLKVIRELEF
ERVHLAGYSIRPLTYSASLPQVPTRVKKERVLRALQVIEEVGLKIRLKYVGKEVECFTTEHSNTWICRLENYIPVVVTGK
SGDPALDYGRWIRVLVDNATFFDLRGRFLESK
>Mature_432_residues
MRVYIETYGCALNKSDEALMVENILREGHELVNSIEDADTLIINTCIVRLDTEYHMVKRIRELYEVASRTGKKLIVAGCM
AKAEPYTVLKIAPEASLVSPQNSALITEVLKTRGKVILIDGLRERDRIGIHVEDRIAPIPIQEGCLSNCSFCITKHARRI
LVSHGIDAVVKAVERAVRNGAVEIQLTGMDLGTYGLDLYKTRKLPELVKEVSRRVSGEYMIRIGMINPEHLRYILDDLID
AINESSKVYRFLHIPLQSGSNKVLSVMRRNYSVEEYIEIVNEAKSRIPGVSIATDIIVGHPMEDEEDFNETLKVIRELEF
ERVHLAGYSIRPLTYSASLPQVPTRVKKERVLRALQVIEEVGLKIRLKYVGKEVECFTTEHSNTWICRLENYIPVVVTGK
SGDPALDYGRWIRVLVDNATFFDLRGRFLESK

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=364, Percent_Identity=33.7912087912088, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI28872782, Length=410, Percent_Identity=27.0731707317073, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI28872784, Length=410, Percent_Identity=27.0731707317073, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1786882, Length=367, Percent_Identity=28.3378746594005, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787057, Length=435, Percent_Identity=28.0459770114943, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71996771, Length=215, Percent_Identity=37.6744186046512, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17553146, Length=461, Percent_Identity=22.3427331887202, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19922432, Length=368, Percent_Identity=32.6086956521739, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI21356207, Length=481, Percent_Identity=25.1559251559252, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR016027
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 49054; Mature: 49054

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVYIETYGCALNKSDEALMVENILREGHELVNSIEDADTLIINTCIVRLDTEYHMVKRI
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHH
RELYEVASRTGKKLIVAGCMAKAEPYTVLKIAPEASLVSPQNSALITEVLKTRGKVILID
HHHHHHHHCCCCEEEEEEHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEE
GLRERDRIGIHVEDRIAPIPIQEGCLSNCSFCITKHARRILVSHGIDAVVKAVERAVRNG
CCCCCCCCCEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
AVEIQLTGMDLGTYGLDLYKTRKLPELVKEVSRRVSGEYMIRIGMINPEHLRYILDDLID
CEEEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHH
AINESSKVYRFLHIPLQSGSNKVLSVMRRNYSVEEYIEIVNEAKSRIPGVSIATDIIVGH
HHCCCCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHEECC
PMEDEEDFNETLKVIRELEFERVHLAGYSIRPLTYSASLPQVPTRVKKERVLRALQVIEE
CCCCHHHHHHHHHHHHHHCCCEEEECCEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHH
VGLKIRLKYVGKEVECFTTEHSNTWICRLENYIPVVVTGKSGDPALDYGRWIRVLVDNAT
CCCEEEEEECCCEEEEEEECCCCEEEEEECCCEEEEEECCCCCCCHHHHHEEEEEECCCE
FFDLRGRFLESK
EEECCCHHCCCC
>Mature Secondary Structure
MRVYIETYGCALNKSDEALMVENILREGHELVNSIEDADTLIINTCIVRLDTEYHMVKRI
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHH
RELYEVASRTGKKLIVAGCMAKAEPYTVLKIAPEASLVSPQNSALITEVLKTRGKVILID
HHHHHHHHCCCCEEEEEEHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEE
GLRERDRIGIHVEDRIAPIPIQEGCLSNCSFCITKHARRILVSHGIDAVVKAVERAVRNG
CCCCCCCCCEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
AVEIQLTGMDLGTYGLDLYKTRKLPELVKEVSRRVSGEYMIRIGMINPEHLRYILDDLID
CEEEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHH
AINESSKVYRFLHIPLQSGSNKVLSVMRRNYSVEEYIEIVNEAKSRIPGVSIATDIIVGH
HHCCCCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHEECC
PMEDEEDFNETLKVIRELEFERVHLAGYSIRPLTYSASLPQVPTRVKKERVLRALQVIEE
CCCCHHHHHHHHHHHHHHCCCEEEECCEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHH
VGLKIRLKYVGKEVECFTTEHSNTWICRLENYIPVVVTGKSGDPALDYGRWIRVLVDNAT
CCCEEEEEECCCEEEEEEECCCCEEEEEECCCEEEEEECCCCCCCHHHHHEEEEEECCCE
FFDLRGRFLESK
EEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]