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The map label for this gene is ygbD [C]

Identifier: 218883752

GI number: 218883752

Start: 409652

End: 411064

Strand: Reverse

Name: ygbD [C]

Synonym: DKAM_0441

Alternate gene names: 218883752

Gene position: 411064-409652 (Counterclockwise)

Preceding gene: 218883753

Following gene: 218883746

Centisome position: 30.11

GC content: 48.41

Gene sequence:

>1413_bases
ATGAGGAGATATGATGTAGTCGTGGTAGGCGGTGGGGCAGCCGGGTTCACAGCTGCCTTAACAGCTAGGATGCTCTACCC
TGAGCTAAGCGTCTTAATGATAACTAGGAGCGATAAGATTCCCATAGCCTGCACACTCCCATACGCTATAGCCGGTAACA
GACCCCTCGAAGACTACTTAATGCCATACAATTACGCATCCATGTTAGGGGTGGAAATATTAGTTGATGAGGTAGTTGGA
GTCGACACGGAGAACAGGGTTGTTAAAACCAGGAATGGTGTAGAGGTATCCTTCGGCAACCTGATAATAGCCACGGGCTC
CAAGCCCGAGGCCTACAAGGTTGAAGGAGTGGAGCTCCAAGGAGTATACGTTCTAGGAAAGGACTATGATAAACTGACTG
AACTGAGGAAAGTGGTGAACCATGACGGGATCAGGATAGTGGTTGTTGGAAGCGGGTTGACAACAATTGAGCTGGCTGAT
GCCTTAAGCGGTATCCCAGGACTCATAGACCATGTCAAGAGAGGGGTCACAGTGATCTCTAGGAGAAGATATATTTTATC
AAGATACTTCGACAGCGAGTTCGCTGAGATAGCCGAAAAGGAGCTTGTATCCAAGGGCGTGAAGATATACACTAATACAA
GGATTAAGAGAATACTTGGTGAGACAAGTGTTAAGGGTGTAGAGCTCGACAATGGGGAGACTGTGGAGGCTGATATCGTT
ATCATAGTGCCTACATGGGTTCCCGATACAGAGTTAGCAGTTAAAGCAGGCCTCGACGTGTTGAGACAGGGCGTAATCGT
CAACGACTACATGCAGACAGGGAAGCCATACGTGTACGCTGCAGGGGACTGCATAGTGAAACGGGACTTCCTCACAAGTG
GTATGAGGGATATAAAGCTAGCTACCCTGGCATGCGAGGAGGCTAGGAGAGCTGTATCAGCTATTAAAGGCGTGGCTTTA
AGCCCTAGCAGGATGGGAAGGATACCGGTCACAGTAACCAGGATAGGCAACATAGTAATGGGTGCTGCAGGCTACATAGA
GACTCATGCATTGAACCAGGGAGTGTCATACATTGTTGGGAGGGCTAAAGCAGTAAACAGACACCCAGTATGGTTCCCCG
GTGGATGCGAGGTACAGGTGAAGCTTCTCTTCCTCCAGGATGGTAGACTAATAGGTGGACAGGTGGCTGGAGCCTGCAAT
GAGGTAGCGGAAATAACGAACACCATAGCAGTAGCCATGCAGGGCTCTCTAAGGATAGAGGACTTAATCATAGGACTCCA
GCATGGCTCACACCCGTTATTAACATACTCACCAGTAATGCATCCATTAATAAACGCGGCTATCGATGCATACATGAAGA
TGAAAGGATGCGGCTGCCAAGGAGTAAGTAATTACAATATCACTTCCTCCTGA

Upstream 100 bases:

>100_bases
CCCCGAGAACCTAAGGGATCTCTTGGAAGAATAGTGCTTGAAAACAATATATGACTGATATATAGTACATGGATAAATAT
ATGTGTTTGGCGAATCTAAC

Downstream 100 bases:

>100_bases
ATGTGCCGAGGATTAAGAATCCTAGACTACGGAAGAGTATGAAGAGTGAGGTATAGCCTATCATATCTATTTTGTTGAAG
TATCCCCCGAGAACCAGTAT

Product: NADH:polysulfide oxidoreductase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MRRYDVVVVGGGAAGFTAALTARMLYPELSVLMITRSDKIPIACTLPYAIAGNRPLEDYLMPYNYASMLGVEILVDEVVG
VDTENRVVKTRNGVEVSFGNLIIATGSKPEAYKVEGVELQGVYVLGKDYDKLTELRKVVNHDGIRIVVVGSGLTTIELAD
ALSGIPGLIDHVKRGVTVISRRRYILSRYFDSEFAEIAEKELVSKGVKIYTNTRIKRILGETSVKGVELDNGETVEADIV
IIVPTWVPDTELAVKAGLDVLRQGVIVNDYMQTGKPYVYAAGDCIVKRDFLTSGMRDIKLATLACEEARRAVSAIKGVAL
SPSRMGRIPVTVTRIGNIVMGAAGYIETHALNQGVSYIVGRAKAVNRHPVWFPGGCEVQVKLLFLQDGRLIGGQVAGACN
EVAEITNTIAVAMQGSLRIEDLIIGLQHGSHPLLTYSPVMHPLINAAIDAYMKMKGCGCQGVSNYNITSS

Sequences:

>Translated_470_residues
MRRYDVVVVGGGAAGFTAALTARMLYPELSVLMITRSDKIPIACTLPYAIAGNRPLEDYLMPYNYASMLGVEILVDEVVG
VDTENRVVKTRNGVEVSFGNLIIATGSKPEAYKVEGVELQGVYVLGKDYDKLTELRKVVNHDGIRIVVVGSGLTTIELAD
ALSGIPGLIDHVKRGVTVISRRRYILSRYFDSEFAEIAEKELVSKGVKIYTNTRIKRILGETSVKGVELDNGETVEADIV
IIVPTWVPDTELAVKAGLDVLRQGVIVNDYMQTGKPYVYAAGDCIVKRDFLTSGMRDIKLATLACEEARRAVSAIKGVAL
SPSRMGRIPVTVTRIGNIVMGAAGYIETHALNQGVSYIVGRAKAVNRHPVWFPGGCEVQVKLLFLQDGRLIGGQVAGACN
EVAEITNTIAVAMQGSLRIEDLIIGLQHGSHPLLTYSPVMHPLINAAIDAYMKMKGCGCQGVSNYNITSS
>Mature_470_residues
MRRYDVVVVGGGAAGFTAALTARMLYPELSVLMITRSDKIPIACTLPYAIAGNRPLEDYLMPYNYASMLGVEILVDEVVG
VDTENRVVKTRNGVEVSFGNLIIATGSKPEAYKVEGVELQGVYVLGKDYDKLTELRKVVNHDGIRIVVVGSGLTTIELAD
ALSGIPGLIDHVKRGVTVISRRRYILSRYFDSEFAEIAEKELVSKGVKIYTNTRIKRILGETSVKGVELDNGETVEADIV
IIVPTWVPDTELAVKAGLDVLRQGVIVNDYMQTGKPYVYAAGDCIVKRDFLTSGMRDIKLATLACEEARRAVSAIKGVAL
SPSRMGRIPVTVTRIGNIVMGAAGYIETHALNQGVSYIVGRAKAVNRHPVWFPGGCEVQVKLLFLQDGRLIGGQVAGACN
EVAEITNTIAVAMQGSLRIEDLIIGLQHGSHPLLTYSPVMHPLINAAIDAYMKMKGCGCQGVSNYNITSS

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=348, Percent_Identity=25.2873563218391, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI65787454, Length=348, Percent_Identity=25.2873563218391, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI21389617, Length=348, Percent_Identity=25.2873563218391, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1789065, Length=210, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789765, Length=221, Percent_Identity=28.5067873303167, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788892, Length=302, Percent_Identity=23.841059602649, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24581020, Length=319, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573993, Length=319, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 50833; Mature: 50833

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRYDVVVVGGGAAGFTAALTARMLYPELSVLMITRSDKIPIACTLPYAIAGNRPLEDYL
CCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCEEECCCCCHHHHC
MPYNYASMLGVEILVDEVVGVDTENRVVKTRNGVEVSFGNLIIATGSKPEAYKVEGVELQ
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEECCEEEEECCCCCCEEECCEEEE
GVYVLGKDYDKLTELRKVVNHDGIRIVVVGSGLTTIELADALSGIPGLIDHVKRGVTVIS
EEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHCCCHHHHHHHHHCHHHHH
RRRYILSRYFDSEFAEIAEKELVSKGVKIYTNTRIKRILGETSVKGVELDNGETVEADIV
HHHHHHHHHHCHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCEEECCCCCEEEEEEE
IIVPTWVPDTELAVKAGLDVLRQGVIVNDYMQTGKPYVYAAGDCIVKRDFLTSGMRDIKL
EEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHCCCCEEEECCCEEEEHHHHHCCCHHHHH
ATLACEEARRAVSAIKGVALSPSRMGRIPVTVTRIGNIVMGAAGYIETHALNQGVSYIVG
HHHHHHHHHHHHHHHHCCEECHHHCCCCCEEEEECCCEEECCCCHHHHHHHHCCHHHHHH
RAKAVNRHPVWFPGGCEVQVKLLFLQDGRLIGGQVAGACNEVAEITNTIAVAMQGSLRIE
HHHCCCCCCCCCCCCCEEEEEEEEEECCCEECCHHHHHHHHHHHHHHHEEEEEECCEEEE
DLIIGLQHGSHPLLTYSPVMHPLINAAIDAYMKMKGCGCQGVSNYNITSS
EEEEEECCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRYDVVVVGGGAAGFTAALTARMLYPELSVLMITRSDKIPIACTLPYAIAGNRPLEDYL
CCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCEEECCCCCHHHHC
MPYNYASMLGVEILVDEVVGVDTENRVVKTRNGVEVSFGNLIIATGSKPEAYKVEGVELQ
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEECCEEEEECCCCCCEEECCEEEE
GVYVLGKDYDKLTELRKVVNHDGIRIVVVGSGLTTIELADALSGIPGLIDHVKRGVTVIS
EEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHCCCHHHHHHHHHCHHHHH
RRRYILSRYFDSEFAEIAEKELVSKGVKIYTNTRIKRILGETSVKGVELDNGETVEADIV
HHHHHHHHHHCHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCEEECCCCCEEEEEEE
IIVPTWVPDTELAVKAGLDVLRQGVIVNDYMQTGKPYVYAAGDCIVKRDFLTSGMRDIKL
EEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHCCCCEEEECCCEEEEHHHHHCCCHHHHH
ATLACEEARRAVSAIKGVALSPSRMGRIPVTVTRIGNIVMGAAGYIETHALNQGVSYIVG
HHHHHHHHHHHHHHHHCCEECHHHCCCCCEEEEECCCEEECCCCHHHHHHHHCCHHHHHH
RAKAVNRHPVWFPGGCEVQVKLLFLQDGRLIGGQVAGACNEVAEITNTIAVAMQGSLRIE
HHHCCCCCCCCCCCCCEEEEEEEEEECCCEECCHHHHHHHHHHHHHHHEEEEEECCEEEE
DLIIGLQHGSHPLLTYSPVMHPLINAAIDAYMKMKGCGCQGVSNYNITSS
EEEEEECCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]