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The map label for this gene is mptA [H]

Identifier: 218883738

GI number: 218883738

Start: 398459

End: 399331

Strand: Reverse

Name: mptA [H]

Synonym: DKAM_0427

Alternate gene names: 218883738

Gene position: 399331-398459 (Counterclockwise)

Preceding gene: 218883739

Following gene: 218883737

Centisome position: 29.25

GC content: 46.85

Gene sequence:

>873_bases
GTGGAAGTGGTTGATGTGGCCCACGATGGGATCCCCGATGTCCACAGTGAGAAACCCCCATTCGAGTTGGATGTGGATAA
TGTTGGCTTAAGAGGGCTTCGTGGACCCATTATGAAGATTAGGGAATACATGGTTATCCCGGTATTCAAGGTGTCGGTTA
GCTTACCGGCATCATTTAGGGGGGCTCATTTATCGCGTTTATACAGGGCTTATACAGGGGTTGTGAAACCAGGTGCCGAG
CTAACAATGGATTTACTGAGGCAGCTAGCCATAAGGCTACTCGAGGTAAACGAGTATGCTGTGAGAGCCATGGTTTCAGT
TAAGGGGAGGCTCTATCATACGGTGGATCGGGGAGGTGTACCGGAGTACTCTAGCAACGGTTTTATATACGCTGGCGTGA
GGTATGAGCGTGGAGGCAGCGTGAGTGAATACACTGGTGGAGGCATTTACGGGTTAACCACCTGTCCATGTGCAGGAGCG
GTCTCTAGACATATATATGGGGAACCCTACACCCACATGCAGAAGGTAAGGATTAATGCATATATTAAGTCCAGTAAAAC
CCTTATCGAGCCCATAGAGGTCTTCGAGAAGCTTAATACAGTTGTCTACACACCACGTAACTACCTTAAGAGGATTGAGG
AGGCCGAATTCGTTAAGATGATATATGAGAAGCCGCTGTTCACAGAGGATATCGCCAGGCTTGCAGCAGTTAAGCTAGCC
GAGCTAGTGGCTAACCATGGAATCAGCGGGCCCGATGGAATATTATATGTGAGTGTAAGATCCTATGAAACCATACACGA
GTACATTGTTGAATCAATAGTTAGAACCAGGTTAACCGATATCGCTGGCTTTAAGATAATTAATAAGACTTAA

Upstream 100 bases:

>100_bases
GGGGTTAAAGCATCCAAGAGACTTGAGGGTTCTAAGAGAATAGATGAACTAGTTAATGAGGTATCAAACTTCATCAAGAG
TGTTAAGGGTAGTCAAGTAA

Downstream 100 bases:

>100_bases
ATAGGGTGGTTAATTGAGCTGGGTAATAGATCCCTCTGAGTGGAAACCGTTGTATAATTACATAAAGTCCAGGCTGAACC
TTTCATTTGATAGGGATCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MEVVDVAHDGIPDVHSEKPPFELDVDNVGLRGLRGPIMKIREYMVIPVFKVSVSLPASFRGAHLSRLYRAYTGVVKPGAE
LTMDLLRQLAIRLLEVNEYAVRAMVSVKGRLYHTVDRGGVPEYSSNGFIYAGVRYERGGSVSEYTGGGIYGLTTCPCAGA
VSRHIYGEPYTHMQKVRINAYIKSSKTLIEPIEVFEKLNTVVYTPRNYLKRIEEAEFVKMIYEKPLFTEDIARLAAVKLA
ELVANHGISGPDGILYVSVRSYETIHEYIVESIVRTRLTDIAGFKIINKT

Sequences:

>Translated_290_residues
MEVVDVAHDGIPDVHSEKPPFELDVDNVGLRGLRGPIMKIREYMVIPVFKVSVSLPASFRGAHLSRLYRAYTGVVKPGAE
LTMDLLRQLAIRLLEVNEYAVRAMVSVKGRLYHTVDRGGVPEYSSNGFIYAGVRYERGGSVSEYTGGGIYGLTTCPCAGA
VSRHIYGEPYTHMQKVRINAYIKSSKTLIEPIEVFEKLNTVVYTPRNYLKRIEEAEFVKMIYEKPLFTEDIARLAAVKLA
ELVANHGISGPDGILYVSVRSYETIHEYIVESIVRTRLTDIAGFKIINKT
>Mature_290_residues
MEVVDVAHDGIPDVHSEKPPFELDVDNVGLRGLRGPIMKIREYMVIPVFKVSVSLPASFRGAHLSRLYRAYTGVVKPGAE
LTMDLLRQLAIRLLEVNEYAVRAMVSVKGRLYHTVDRGGVPEYSSNGFIYAGVRYERGGSVSEYTGGGIYGLTTCPCAGA
VSRHIYGEPYTHMQKVRINAYIKSSKTLIEPIEVFEKLNTVVYTPRNYLKRIEEAEFVKMIYEKPLFTEDIARLAAVKLA
ELVANHGISGPDGILYVSVRSYETIHEYIVESIVRTRLTDIAGFKIINKT

Specific function: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003801
- InterPro:   IPR022840
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: NA

Molecular weight: Translated: 32464; Mature: 32464

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVVDVAHDGIPDVHSEKPPFELDVDNVGLRGLRGPIMKIREYMVIPVFKVSVSLPASFR
CCEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHEEEEEEEEEECCCCCC
GAHLSRLYRAYTGVVKPGAELTMDLLRQLAIRLLEVNEYAVRAMVSVKGRLYHTVDRGGV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
PEYSSNGFIYAGVRYERGGSVSEYTGGGIYGLTTCPCAGAVSRHIYGEPYTHMQKVRINA
CCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHCCCCCHHHHHHEEEEE
YIKSSKTLIEPIEVFEKLNTVVYTPRNYLKRIEEAEFVKMIYEKPLFTEDIARLAAVKLA
EEECCCHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ELVANHGISGPDGILYVSVRSYETIHEYIVESIVRTRLTDIAGFKIINKT
HHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCEEEECCC
>Mature Secondary Structure
MEVVDVAHDGIPDVHSEKPPFELDVDNVGLRGLRGPIMKIREYMVIPVFKVSVSLPASFR
CCEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHEEEEEEEEEECCCCCC
GAHLSRLYRAYTGVVKPGAELTMDLLRQLAIRLLEVNEYAVRAMVSVKGRLYHTVDRGGV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
PEYSSNGFIYAGVRYERGGSVSEYTGGGIYGLTTCPCAGAVSRHIYGEPYTHMQKVRINA
CCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHCCCCCHHHHHHEEEEE
YIKSSKTLIEPIEVFEKLNTVVYTPRNYLKRIEEAEFVKMIYEKPLFTEDIARLAAVKLA
EEECCCHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ELVANHGISGPDGILYVSVRSYETIHEYIVESIVRTRLTDIAGFKIINKT
HHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11121031 [H]