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The map label for this gene is cysA [C]

Identifier: 218883551

GI number: 218883551

Start: 222783

End: 223505

Strand: Direct

Name: cysA [C]

Synonym: DKAM_0240

Alternate gene names: 218883551

Gene position: 222783-223505 (Clockwise)

Preceding gene: 218883550

Following gene: 218883552

Centisome position: 16.32

GC content: 46.2

Gene sequence:

>723_bases
GTGAACGAGGTGAGAGGTGTAGATTTATCAATAGGTTATTCGCCGGGTAAACCGTTAATAGAGGATGCAGAGTTCACTCT
AGGCCCTGGGCTCCACGTATTGATCGGTGCTAATGGAAGTGGTAAGTCGACGCTGTTGAAGACGATAGCTGGGATAATAA
AGCCTTTGAAGGGTAGTGTAGAGGTAAACAGTGTAAATATACATGACATACGTAGGCGGGAAGCAGTAAGGCTTGTAGGA
TATGTGTGGCAGAATCCTTTCCACGGCTTCATAGAGGCTACTGTTGAAAGAGAGATATCATTCATCACGAGGATGACTGG
GGCGCGGGTAAATGGTGAGATACTCTACAGGCTCGTGGATATGGAGTTAATGGATAGAAACCCGTTCACACTAAGCGGGG
GAGAGGCTAGGAGGGTTGCGCTTGCAAGCGTTCTCTCAATAGATCAACCAGTATGGTTGCTCGATGAGCCCTTCTCGGAT
CTAGATTATAACGGCTATCTCATCCTCGCGGAGCTAATAAGGTATGGAGTTAAAAACGGTAAGGTAATCGTTATGACAAC
ACATATTGTTTCACTACTCGATCCACTAGAGCCAAATACTTTTCTATTAATAGACAGGGGCAGGAGACGACTGCTCAAGG
GAGACTGGGGGGATTTAACCGATGACCTATTACTTGGGGCAGGCATAATTCCGAGGAGGATTTCATGTGGCACTACTATA
TGA

Upstream 100 bases:

>100_bases
GGCTTCCAGAGCTAACTATACTCTATATTTTCATAAGCGAGCTAGTCATTATAGGCGTCATAGGTGGATTAGTATATAGG
TCTCTCAGGGTGTTTTTTAA

Downstream 100 bases:

>100_bases
ATCAGTGATGCTGCAGGATAGGGATACATGGCTCAATAGGAAGTGGTTCATCTTATTGAAGCTAATCCTCCTTATTGTTA
ACATAGCCATCATAGTCCTA

Product: ABC transporter-like protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MNEVRGVDLSIGYSPGKPLIEDAEFTLGPGLHVLIGANGSGKSTLLKTIAGIIKPLKGSVEVNSVNIHDIRRREAVRLVG
YVWQNPFHGFIEATVEREISFITRMTGARVNGEILYRLVDMELMDRNPFTLSGGEARRVALASVLSIDQPVWLLDEPFSD
LDYNGYLILAELIRYGVKNGKVIVMTTHIVSLLDPLEPNTFLLIDRGRRRLLKGDWGDLTDDLLLGAGIIPRRISCGTTI

Sequences:

>Translated_240_residues
MNEVRGVDLSIGYSPGKPLIEDAEFTLGPGLHVLIGANGSGKSTLLKTIAGIIKPLKGSVEVNSVNIHDIRRREAVRLVG
YVWQNPFHGFIEATVEREISFITRMTGARVNGEILYRLVDMELMDRNPFTLSGGEARRVALASVLSIDQPVWLLDEPFSD
LDYNGYLILAELIRYGVKNGKVIVMTTHIVSLLDPLEPNTFLLIDRGRRRLLKGDWGDLTDDLLLGAGIIPRRISCGTTI
>Mature_240_residues
MNEVRGVDLSIGYSPGKPLIEDAEFTLGPGLHVLIGANGSGKSTLLKTIAGIIKPLKGSVEVNSVNIHDIRRREAVRLVG
YVWQNPFHGFIEATVEREISFITRMTGARVNGEILYRLVDMELMDRNPFTLSGGEARRVALASVLSIDQPVWLLDEPFSD
LDYNGYLILAELIRYGVKNGKVIVMTTHIVSLLDPLEPNTFLLIDRGRRRLLKGDWGDLTDDLLLGAGIIPRRISCGTTI

Specific function: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system [H]

COG id: COG1122

COG function: function code P; ABC-type cobalt transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=196, Percent_Identity=28.0612244897959, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI27262626, Length=196, Percent_Identity=28.0612244897959, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1788761, Length=141, Percent_Identity=35.4609929078014, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790467, Length=201, Percent_Identity=31.8407960199005, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081791, Length=182, Percent_Identity=31.8681318681319, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789873, Length=204, Percent_Identity=30.3921568627451, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788450, Length=169, Percent_Identity=34.3195266272189, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786253, Length=202, Percent_Identity=31.1881188118812, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790739, Length=198, Percent_Identity=30.8080808080808, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786803, Length=188, Percent_Identity=30.8510638297872, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787029, Length=189, Percent_Identity=29.6296296296296, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082267, Length=157, Percent_Identity=30.5732484076433, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790534, Length=186, Percent_Identity=31.7204301075269, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786563, Length=182, Percent_Identity=30.2197802197802, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790525, Length=190, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081834, Length=190, Percent_Identity=27.8947368421053, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994997, Length=191, Percent_Identity=30.3664921465969, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI87081709, Length=171, Percent_Identity=30.9941520467836, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789032, Length=193, Percent_Identity=31.0880829015544, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323959, Length=216, Percent_Identity=27.3148148148148, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324498, Length=202, Percent_Identity=27.7227722772277, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512771, Length=173, Percent_Identity=34.1040462427746, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666092, Length=193, Percent_Identity=30.5699481865285, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161077321, Length=225, Percent_Identity=28.4444444444444, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643674, Length=201, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.25 [C]

Molecular weight: Translated: 26535; Mature: 26535

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVRGVDLSIGYSPGKPLIEDAEFTLGPGLHVLIGANGSGKSTLLKTIAGIIKPLKGSV
CCCCCCEEEEECCCCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCE
EVNSVNIHDIRRREAVRLVGYVWQNPFHGFIEATVEREISFITRMTGARVNGEILYRLVD
EEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEC
MELMDRNPFTLSGGEARRVALASVLSIDQPVWLLDEPFSDLDYNGYLILAELIRYGVKNG
HHHHCCCCEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEHHHHHHHHCCCCC
KVIVMTTHIVSLLDPLEPNTFLLIDRGRRRLLKGDWGDLTDDLLLGAGIIPRRISCGTTI
EEEEEHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNEVRGVDLSIGYSPGKPLIEDAEFTLGPGLHVLIGANGSGKSTLLKTIAGIIKPLKGSV
CCCCCCEEEEECCCCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCE
EVNSVNIHDIRRREAVRLVGYVWQNPFHGFIEATVEREISFITRMTGARVNGEILYRLVD
EEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEC
MELMDRNPFTLSGGEARRVALASVLSIDQPVWLLDEPFSDLDYNGYLILAELIRYGVKNG
HHHHCCCCEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEHHHHHHHHCCCCC
KVIVMTTHIVSLLDPLEPNTFLLIDRGRRRLLKGDWGDLTDDLLLGAGIIPRRISCGTTI
EEEEEHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA