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The map label for this gene is lhr [C]

Identifier: 218883465

GI number: 218883465

Start: 136992

End: 139652

Strand: Reverse

Name: lhr [C]

Synonym: DKAM_0151

Alternate gene names: 218883465

Gene position: 139652-136992 (Counterclockwise)

Preceding gene: 218883466

Following gene: 218883464

Centisome position: 10.23

GC content: 45.85

Gene sequence:

>2661_bases
GTGGGGGAAACGACTATAAGCGTATTTAATGGGGATTTCACAGTTGCAGAGGCCATGGATGGATTAAGACCATATGTAAA
GGAATGGTTCACCAGGAAATACAGGGAACCGACGCCCGTTCAGAGGAAGACCATACCCCTCGTTAAAGAAGGGTTTAACA
TACTGGTTTCAAGCCCTACTGGAACCGGTAAGACCCTGGCAGTCTTCCTCGGGATAATAGATAATATCTACAAGCAATAT
GAGGAAACAGGTAAGATGCCCGAAGGTATTTACGTGGTATATGTGAGCCCGCTTAGAGCACTTAACAACGACATGAGGAA
GAACCTGTTGGAACCAATTGAAGGCATTGTTAACGAGGCAAGGCGCATGGGACTGGAACTCCCCCCTATAAAGATAGCTG
TTAGAACCAGCGATACCACTCAGAGCGAGAAGCAACGCATGAACAGGGATCCCCCGCACATATTGATAACGACCCCTGAG
AGCCTTGCAATATCGTTGAATGCCCCTAAGTTTAGGGAGAAGCTAGCTAACACTAGGATACTCGTGGTCGACGAAATACA
TGAACTAGCCTCAAGTAAGAGGGGGAGTCATCTAGCTGTAAGTATAGAGAGACTTGAGAACCTAGCCGGAAGGCCCCTCC
AAAGAATTGGGTTAAGCGCAACGATATCTCCTCTTGAAGAAGTTGCATTATTCCTAGCCGGTTACAATGATGAAGGAGAG
CCCCGGGACTGCATTATAGTTGATGCTAGATTCGATAAGAAGATGGATATAAGGGTTGTTTCCCCAATCAGGGATTTAGC
GCGAGCATCCGCCGAGGAAATCAATGAGTCAATATATGGAGAGCTGAAGAAGATAATATCAAGGCACCGTACAACACTAG
TATTCACCAATACTAGGAGCGCTACCGAGAGAGTGGTATTCAAGCTCAGGAAGATCTTTGAGAAGGGGGGAGTAATAGAT
ATAGATGATATAGAGGCACACCATAGTAGTCTAAGCAGGGATACCAGGATTGAGATAGAGAATAAGCTTAAGAACGGGGA
ATTAAGAGCCATAGTGAGCTCGACATCACTGGAGCTCGGGATAGACATAGGCTACATCGATATCGTGGTCTTGCTTAGCT
CCCCTAAGAGCGTTACAAGGCTTCTACAGAGAATTGGGAGGGCTGGACACCATATCAGGGAGGTTAGTAAGGGTAGGATA
ATTGTAGTAGACCGCGATGACCTACTTGAGTGCACTGTACTATCTAAACTAGCCCTCGAGAGGAAGATAGATAGGATCAG
GATACCGCGTAATCCACTTGACGTCCTCGCCCAACACATCGTTGGAATGGCGTTAGAGCGGAAATGGAGGATCGATGAAG
CCTATAGTCTTGTGAAGAGAACATATACATTCCATGATCTAAGCTACGATGACTTCCTCTCGACGCTGAGATACTTGGCT
GGACAACTGGGAGATTTCTACGAGTATCAAAGAGTCTACTCCAAGATATGGCTGGATGAAGAAGAAGGCATATTCGGCAG
GAAGAAATCCACACGAATGATATACTATCAAAACATAGGGGTTATACCAGATGAAAGTAAAGTACACGTGTTCACGGTGG
ATAATAAGTACGTTGGAGACCTCGAGGAGGGATTCGTAGAGTACTTATCACAGGGAGACTTATTCGTGCTAGGTGGTAGA
GTATATGAGTACCTATATAGCAGGGGTCTCAAGGTCGTGGTTAAGCCGGCGGATGGACAAAGACCCACGGTTCCCTCCTG
GTTCAGCGAGATGCTGCCCCTCTCCTATGACTCAGCCAGGGAGGTTGGATGCTTTAGACGTGTAATCGCTGAAATGCTTG
ATGAGAAGGACCGTGAAGAAGTGGTTGAGTACCTTGTAAAGGAGTATAAGCTGCAAAAACATGCGGCCGAGACTATTTGC
GACTACATAATGGATCAAAAGCTCTATACAAAGGGACTCGTGCCTTCAGATAAATTGATACTTATAGAAATATATGATGA
GCCAACACGGAGAAATATAATCGTACACTCGATCTTTGGACGAAAAGCAAACGACGCTCTTGCCAGGCTATATGCTTACA
CCGTGGGGCAGAGACTAGGGGTGAATATCAGGTTAACGGTAACCGATAACGGCTTCATGCTTACGATCCCCGGTCATCCG
CAAGGCAAATGGGTTGAGTGGTTTAAATCAATACCACCGGATCAAGCGTGGGACATGCTGGAGAGAATTATTAGAAGAAC
AGATCTACTCAAACGGAGGTTCAGGCATACTGCTGTCAGGAGCTTTATGCTATTGAGAAAATACAGGGATACGGAGAAAA
GCGTTAACAGGCTACAGGTTAATGCTGAGGAATTACTGAAGGCCGTCGAAGAGATGCAGGGATTTCCGGTTCTCAAGGAG
ACTTATAGGGAGATCTTAATGGATTACATGCATATAGATGAAGCGATAGAGGTCCTTAGTATGGTCAGAAACGGGGAGAT
AGAGGTGGCACTACTAGGACCACTTGATGTACCAAGTCCCTTCGCGCATAGCATAGTCGTGCATGGATACAGTGACGTGG
TGTTAATGGAGGATATGCGTAGAATGCTTATAAGACTCCACGAGCTCGTTAAGGAGAGGTTATCCAGTTCTAACATGGAT
ACGTGGAATACCATTAATTAA

Upstream 100 bases:

>100_bases
ATTGCCAACTCCAGTGCATATAGCTATGTTGTTTATAGGTGGCGTAAAGATGTATTCTTCAATTAGTAGTGCCTACACTG
GTTGAAAAAACAAGTAATAG

Downstream 100 bases:

>100_bases
GTAGGATCATGTATTTAGAGATATAGGGATCGACTATGAGCCTGGAGGTACAGGGGCTTTCAGTGGCTGTAGACGATAGG
ATAGTACTTAGAGACATCTC

Product: ATP-dependent helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 886; Mature: 885

Protein sequence:

>886_residues
MGETTISVFNGDFTVAEAMDGLRPYVKEWFTRKYREPTPVQRKTIPLVKEGFNILVSSPTGTGKTLAVFLGIIDNIYKQY
EETGKMPEGIYVVYVSPLRALNNDMRKNLLEPIEGIVNEARRMGLELPPIKIAVRTSDTTQSEKQRMNRDPPHILITTPE
SLAISLNAPKFREKLANTRILVVDEIHELASSKRGSHLAVSIERLENLAGRPLQRIGLSATISPLEEVALFLAGYNDEGE
PRDCIIVDARFDKKMDIRVVSPIRDLARASAEEINESIYGELKKIISRHRTTLVFTNTRSATERVVFKLRKIFEKGGVID
IDDIEAHHSSLSRDTRIEIENKLKNGELRAIVSSTSLELGIDIGYIDIVVLLSSPKSVTRLLQRIGRAGHHIREVSKGRI
IVVDRDDLLECTVLSKLALERKIDRIRIPRNPLDVLAQHIVGMALERKWRIDEAYSLVKRTYTFHDLSYDDFLSTLRYLA
GQLGDFYEYQRVYSKIWLDEEEGIFGRKKSTRMIYYQNIGVIPDESKVHVFTVDNKYVGDLEEGFVEYLSQGDLFVLGGR
VYEYLYSRGLKVVVKPADGQRPTVPSWFSEMLPLSYDSAREVGCFRRVIAEMLDEKDREEVVEYLVKEYKLQKHAAETIC
DYIMDQKLYTKGLVPSDKLILIEIYDEPTRRNIIVHSIFGRKANDALARLYAYTVGQRLGVNIRLTVTDNGFMLTIPGHP
QGKWVEWFKSIPPDQAWDMLERIIRRTDLLKRRFRHTAVRSFMLLRKYRDTEKSVNRLQVNAEELLKAVEEMQGFPVLKE
TYREILMDYMHIDEAIEVLSMVRNGEIEVALLGPLDVPSPFAHSIVVHGYSDVVLMEDMRRMLIRLHELVKERLSSSNMD
TWNTIN

Sequences:

>Translated_886_residues
MGETTISVFNGDFTVAEAMDGLRPYVKEWFTRKYREPTPVQRKTIPLVKEGFNILVSSPTGTGKTLAVFLGIIDNIYKQY
EETGKMPEGIYVVYVSPLRALNNDMRKNLLEPIEGIVNEARRMGLELPPIKIAVRTSDTTQSEKQRMNRDPPHILITTPE
SLAISLNAPKFREKLANTRILVVDEIHELASSKRGSHLAVSIERLENLAGRPLQRIGLSATISPLEEVALFLAGYNDEGE
PRDCIIVDARFDKKMDIRVVSPIRDLARASAEEINESIYGELKKIISRHRTTLVFTNTRSATERVVFKLRKIFEKGGVID
IDDIEAHHSSLSRDTRIEIENKLKNGELRAIVSSTSLELGIDIGYIDIVVLLSSPKSVTRLLQRIGRAGHHIREVSKGRI
IVVDRDDLLECTVLSKLALERKIDRIRIPRNPLDVLAQHIVGMALERKWRIDEAYSLVKRTYTFHDLSYDDFLSTLRYLA
GQLGDFYEYQRVYSKIWLDEEEGIFGRKKSTRMIYYQNIGVIPDESKVHVFTVDNKYVGDLEEGFVEYLSQGDLFVLGGR
VYEYLYSRGLKVVVKPADGQRPTVPSWFSEMLPLSYDSAREVGCFRRVIAEMLDEKDREEVVEYLVKEYKLQKHAAETIC
DYIMDQKLYTKGLVPSDKLILIEIYDEPTRRNIIVHSIFGRKANDALARLYAYTVGQRLGVNIRLTVTDNGFMLTIPGHP
QGKWVEWFKSIPPDQAWDMLERIIRRTDLLKRRFRHTAVRSFMLLRKYRDTEKSVNRLQVNAEELLKAVEEMQGFPVLKE
TYREILMDYMHIDEAIEVLSMVRNGEIEVALLGPLDVPSPFAHSIVVHGYSDVVLMEDMRRMLIRLHELVKERLSSSNMD
TWNTIN
>Mature_885_residues
GETTISVFNGDFTVAEAMDGLRPYVKEWFTRKYREPTPVQRKTIPLVKEGFNILVSSPTGTGKTLAVFLGIIDNIYKQYE
ETGKMPEGIYVVYVSPLRALNNDMRKNLLEPIEGIVNEARRMGLELPPIKIAVRTSDTTQSEKQRMNRDPPHILITTPES
LAISLNAPKFREKLANTRILVVDEIHELASSKRGSHLAVSIERLENLAGRPLQRIGLSATISPLEEVALFLAGYNDEGEP
RDCIIVDARFDKKMDIRVVSPIRDLARASAEEINESIYGELKKIISRHRTTLVFTNTRSATERVVFKLRKIFEKGGVIDI
DDIEAHHSSLSRDTRIEIENKLKNGELRAIVSSTSLELGIDIGYIDIVVLLSSPKSVTRLLQRIGRAGHHIREVSKGRII
VVDRDDLLECTVLSKLALERKIDRIRIPRNPLDVLAQHIVGMALERKWRIDEAYSLVKRTYTFHDLSYDDFLSTLRYLAG
QLGDFYEYQRVYSKIWLDEEEGIFGRKKSTRMIYYQNIGVIPDESKVHVFTVDNKYVGDLEEGFVEYLSQGDLFVLGGRV
YEYLYSRGLKVVVKPADGQRPTVPSWFSEMLPLSYDSAREVGCFRRVIAEMLDEKDREEVVEYLVKEYKLQKHAAETICD
YIMDQKLYTKGLVPSDKLILIEIYDEPTRRNIIVHSIFGRKANDALARLYAYTVGQRLGVNIRLTVTDNGFMLTIPGHPQ
GKWVEWFKSIPPDQAWDMLERIIRRTDLLKRRFRHTAVRSFMLLRKYRDTEKSVNRLQVNAEELLKAVEEMQGFPVLKET
YREILMDYMHIDEAIEVLSMVRNGEIEVALLGPLDVPSPFAHSIVVHGYSDVVLMEDMRRMLIRLHELVKERLSSSNMDT
WNTIN

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=917, Percent_Identity=29.8800436205016, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17537519, Length=412, Percent_Identity=23.7864077669903, Blast_Score=79, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6320497, Length=369, Percent_Identity=26.2872628726287, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI9755332, Length=401, Percent_Identity=25.6857855361596, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6321020, Length=414, Percent_Identity=26.8115942028986, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321710, Length=380, Percent_Identity=24.2105263157895, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17136814, Length=398, Percent_Identity=20.8542713567839, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 101816; Mature: 101685

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGETTISVFNGDFTVAEAMDGLRPYVKEWFTRKYREPTPVQRKTIPLVKEGFNILVSSPT
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEECCC
GTGKTLAVFLGIIDNIYKQYEETGKMPEGIYVVYVSPLRALNNDMRKNLLEPIEGIVNEA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
RRMGLELPPIKIAVRTSDTTQSEKQRMNRDPPHILITTPESLAISLNAPKFREKLANTRI
HHCCCCCCCEEEEEECCCCCHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHCCCEE
LVVDEIHELASSKRGSHLAVSIERLENLAGRPLQRIGLSATISPLEEVALFLAGYNDEGE
EEHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCC
PRDCIIVDARFDKKMDIRVVSPIRDLARASAEEINESIYGELKKIISRHRTTLVFTNTRS
CCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCH
ATERVVFKLRKIFEKGGVIDIDDIEAHHSSLSRDTRIEIENKLKNGELRAIVSSTSLELG
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCEEEEHHCCCCCCEEEEEECCCEEEE
IDIGYIDIVVLLSSPKSVTRLLQRIGRAGHHIREVSKGRIIVVDRDDLLECTVLSKLALE
EEECHHHEEEEECCCHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
RKIDRIRIPRNPLDVLAQHIVGMALERKWRIDEAYSLVKRTYTFHDLSYDDFLSTLRYLA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GQLGDFYEYQRVYSKIWLDEEEGIFGRKKSTRMIYYQNIGVIPDESKVHVFTVDNKYVGD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCC
LEEGFVEYLSQGDLFVLGGRVYEYLYSRGLKVVVKPADGQRPTVPSWFSEMLPLSYDSAR
HHHHHHHHHCCCCEEEECHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCHH
EVGCFRRVIAEMLDEKDREEVVEYLVKEYKLQKHAAETICDYIMDQKLYTKGLVPSDKLI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LIEIYDEPTRRNIIVHSIFGRKANDALARLYAYTVGQRLGVNIRLTVTDNGFMLTIPGHP
EEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCC
QGKWVEWFKSIPPDQAWDMLERIIRRTDLLKRRFRHTAVRSFMLLRKYRDTEKSVNRLQV
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NAEELLKAVEEMQGFPVLKETYREILMDYMHIDEAIEVLSMVRNGEIEVALLGPLDVPSP
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
FAHSIVVHGYSDVVLMEDMRRMLIRLHELVKERLSSSNMDTWNTIN
HHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GETTISVFNGDFTVAEAMDGLRPYVKEWFTRKYREPTPVQRKTIPLVKEGFNILVSSPT
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEECCC
GTGKTLAVFLGIIDNIYKQYEETGKMPEGIYVVYVSPLRALNNDMRKNLLEPIEGIVNEA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
RRMGLELPPIKIAVRTSDTTQSEKQRMNRDPPHILITTPESLAISLNAPKFREKLANTRI
HHCCCCCCCEEEEEECCCCCHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHCCCEE
LVVDEIHELASSKRGSHLAVSIERLENLAGRPLQRIGLSATISPLEEVALFLAGYNDEGE
EEHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCC
PRDCIIVDARFDKKMDIRVVSPIRDLARASAEEINESIYGELKKIISRHRTTLVFTNTRS
CCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCH
ATERVVFKLRKIFEKGGVIDIDDIEAHHSSLSRDTRIEIENKLKNGELRAIVSSTSLELG
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCEEEEHHCCCCCCEEEEEECCCEEEE
IDIGYIDIVVLLSSPKSVTRLLQRIGRAGHHIREVSKGRIIVVDRDDLLECTVLSKLALE
EEECHHHEEEEECCCHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
RKIDRIRIPRNPLDVLAQHIVGMALERKWRIDEAYSLVKRTYTFHDLSYDDFLSTLRYLA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GQLGDFYEYQRVYSKIWLDEEEGIFGRKKSTRMIYYQNIGVIPDESKVHVFTVDNKYVGD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCC
LEEGFVEYLSQGDLFVLGGRVYEYLYSRGLKVVVKPADGQRPTVPSWFSEMLPLSYDSAR
HHHHHHHHHCCCCEEEECHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCHH
EVGCFRRVIAEMLDEKDREEVVEYLVKEYKLQKHAAETICDYIMDQKLYTKGLVPSDKLI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LIEIYDEPTRRNIIVHSIFGRKANDALARLYAYTVGQRLGVNIRLTVTDNGFMLTIPGHP
EEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCC
QGKWVEWFKSIPPDQAWDMLERIIRRTDLLKRRFRHTAVRSFMLLRKYRDTEKSVNRLQV
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NAEELLKAVEEMQGFPVLKETYREILMDYMHIDEAIEVLSMVRNGEIEVALLGPLDVPSP
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
FAHSIVVHGYSDVVLMEDMRRMLIRLHELVKERLSSSNMDTWNTIN
HHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]