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The map label for this gene is mat [H]

Identifier: 218883338

GI number: 218883338

Start: 22483

End: 23748

Strand: Reverse

Name: mat [H]

Synonym: DKAM_0024

Alternate gene names: 218883338

Gene position: 23748-22483 (Counterclockwise)

Preceding gene: 218883339

Following gene: 218883333

Centisome position: 1.74

GC content: 44.39

Gene sequence:

>1266_bases
ATGTTAAAGCCAGTAAGGGGGATAATTGTGGGAGGAAGCAGAAATATAGAAATAGAACTTTTAAGAATGACTAGTGTAAG
CAGGATGAAGGTTGAACTAGTCGAGAGAAAAGGAGTAGGACACCCGGACTATATAGCTGACTCGGCAAGCGAGGCTGCTT
CAAGAGCTCTTTCAAAGTACTATTTAAAAGAGTTTGGCACAATATTGCATCACAACCTCGACAAAACACTACTTGTCGGA
GGACAGTCGAACCCCAGATTCGGCGGCGGCGCACTCTTAGAGCCTATATACATAGTAGTTGCAGGCAGGGCTACTACAGA
GGTAAGAGTTGAGGATGGCATAGTTAAAGTACCCTTCGGTAAAATAATTATAGAGGCCGTTAAAGACTGGATTAAGAGGA
ACATGAGATACCTGGATCCAGAGAGACACGTAATAGTGGACTATATGGTTAGAAAGGGTAGTACAGACCTCGTAACAGTA
TTTGATGCAGGGAGATCATCCGTACCCCTTGCAAACGATACAAGTATCGGTGTAGGCTACGCCCCGCTTTCCACACTGGA
AAAACTAGTACTACAGAGTGAGCGATTATTGAACAGTCCAGAGTTTAAATCCAGGGTACCAGCTGTAGGCGAAGACGTGA
AAGTAATGGGTCTGAGAAGGAATAAGGATATAGTGTTAACAATAGCGGCTGCGATAGTCGACAGCGAGGTAAGAGATAAA
TATGAATATCTGAAGGTTAAAGAAGACATAGTAAACGTTGTCTCAGACCTGGCTGGTAGAATAGCTCCAGATTATAATAT
TAAAATACATGTAAACACGGCTGATATACCGGAGAAGAATAGCTTCTACCTAACAGTCACAGGCACCTCTGCCGAGCATG
GAGACGATGGCGCAACCGGGCGGGGCAATCGTGCCAATGGATTAATCCCCCCTATGAGGCCTATAAGCCTTGAGGCGACT
GCTGGGAAGAACCCTGTAAACCACGTGGGCAAGATATACAATGTGGTTGCTAGAAGGATAGCTGAGAGAGTATATGAAGT
ATACAACGGCATATTCTCTGATGTATACGTGGAGCTATTGAGCCAGATCGGTAAGCCGATAGATCAACCGCTTGTCGCAA
GCGTGAAATTGATTCCAAGTGATCTATCGATGAACGATATCCCCTCACACATCATGAGCGAGATCCATGGTATAGCAGAT
GAAGAACTCACTAATATAAAGAGGGTCACCGAGATGGTTCTAAACGATCAAGTAACACTGTACTAA

Upstream 100 bases:

>100_bases
CCCTCTAATGAGGATCGAACCCTAGCTGTTGCTCCTGGGAATTGTAACCTATTATAGTTAAACTTATATTCTATATTAGA
CCTTCTTTAATCCTAGGTAC

Downstream 100 bases:

>100_bases
GCTAGCTGTTTTTCCTAGACCTCTGATACTCTTCTATCATTCTCAATATTCTCTCATGTCTCTCCAACTCGATTAACTCA
TCTATTTTACGCCAGAGCTC

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MLKPVRGIIVGGSRNIEIELLRMTSVSRMKVELVERKGVGHPDYIADSASEAASRALSKYYLKEFGTILHHNLDKTLLVG
GQSNPRFGGGALLEPIYIVVAGRATTEVRVEDGIVKVPFGKIIIEAVKDWIKRNMRYLDPERHVIVDYMVRKGSTDLVTV
FDAGRSSVPLANDTSIGVGYAPLSTLEKLVLQSERLLNSPEFKSRVPAVGEDVKVMGLRRNKDIVLTIAAAIVDSEVRDK
YEYLKVKEDIVNVVSDLAGRIAPDYNIKIHVNTADIPEKNSFYLTVTGTSAEHGDDGATGRGNRANGLIPPMRPISLEAT
AGKNPVNHVGKIYNVVARRIAERVYEVYNGIFSDVYVELLSQIGKPIDQPLVASVKLIPSDLSMNDIPSHIMSEIHGIAD
EELTNIKRVTEMVLNDQVTLY

Sequences:

>Translated_421_residues
MLKPVRGIIVGGSRNIEIELLRMTSVSRMKVELVERKGVGHPDYIADSASEAASRALSKYYLKEFGTILHHNLDKTLLVG
GQSNPRFGGGALLEPIYIVVAGRATTEVRVEDGIVKVPFGKIIIEAVKDWIKRNMRYLDPERHVIVDYMVRKGSTDLVTV
FDAGRSSVPLANDTSIGVGYAPLSTLEKLVLQSERLLNSPEFKSRVPAVGEDVKVMGLRRNKDIVLTIAAAIVDSEVRDK
YEYLKVKEDIVNVVSDLAGRIAPDYNIKIHVNTADIPEKNSFYLTVTGTSAEHGDDGATGRGNRANGLIPPMRPISLEAT
AGKNPVNHVGKIYNVVARRIAERVYEVYNGIFSDVYVELLSQIGKPIDQPLVASVKLIPSDLSMNDIPSHIMSEIHGIAD
EELTNIKRVTEMVLNDQVTLY
>Mature_421_residues
MLKPVRGIIVGGSRNIEIELLRMTSVSRMKVELVERKGVGHPDYIADSASEAASRALSKYYLKEFGTILHHNLDKTLLVG
GQSNPRFGGGALLEPIYIVVAGRATTEVRVEDGIVKVPFGKIIIEAVKDWIKRNMRYLDPERHVIVDYMVRKGSTDLVTV
FDAGRSSVPLANDTSIGVGYAPLSTLEKLVLQSERLLNSPEFKSRVPAVGEDVKVMGLRRNKDIVLTIAAAIVDSEVRDK
YEYLKVKEDIVNVVSDLAGRIAPDYNIKIHVNTADIPEKNSFYLTVTGTSAEHGDDGATGRGNRANGLIPPMRPISLEAT
AGKNPVNHVGKIYNVVARRIAERVYEVYNGIFSDVYVELLSQIGKPIDQPLVASVKLIPSDLSMNDIPSHIMSEIHGIAD
EELTNIKRVTEMVLNDQVTLY

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP [H]

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002795
- ProDom:   PD011777 [H]

Pfam domain/function: PF01941 AdoMet_Synthase [H]

EC number: =2.5.1.6 [H]

Molecular weight: Translated: 46367; Mature: 46367

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPVRGIIVGGSRNIEIELLRMTSVSRMKVELVERKGVGHPDYIADSASEAASRALSKY
CCCCCCEEEECCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHH
YLKEFGTILHHNLDKTLLVGGQSNPRFGGGALLEPIYIVVAGRATTEVRVEDGIVKVPFG
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHCEEEEEEECCCCEEEEECCCEEECCHH
KIIIEAVKDWIKRNMRYLDPERHVIVDYMVRKGSTDLVTVFDAGRSSVPLANDTSIGVGY
HHHHHHHHHHHHCCCCCCCCCHHEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCC
APLSTLEKLVLQSERLLNSPEFKSRVPAVGEDVKVMGLRRNKDIVLTIAAAIVDSEVRDK
CCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHH
YEYLKVKEDIVNVVSDLAGRIAPDYNIKIHVNTADIPEKNSFYLTVTGTSAEHGDDGATG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC
RGNRANGLIPPMRPISLEATAGKNPVNHVGKIYNVVARRIAERVYEVYNGIFSDVYVELL
CCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQIGKPIDQPLVASVKLIPSDLSMNDIPSHIMSEIHGIADEELTNIKRVTEMVLNDQVTL
HHHCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEE
Y
C
>Mature Secondary Structure
MLKPVRGIIVGGSRNIEIELLRMTSVSRMKVELVERKGVGHPDYIADSASEAASRALSKY
CCCCCCEEEECCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHH
YLKEFGTILHHNLDKTLLVGGQSNPRFGGGALLEPIYIVVAGRATTEVRVEDGIVKVPFG
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHCEEEEEEECCCCEEEEECCCEEECCHH
KIIIEAVKDWIKRNMRYLDPERHVIVDYMVRKGSTDLVTVFDAGRSSVPLANDTSIGVGY
HHHHHHHHHHHHCCCCCCCCCHHEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCC
APLSTLEKLVLQSERLLNSPEFKSRVPAVGEDVKVMGLRRNKDIVLTIAAAIVDSEVRDK
CCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHH
YEYLKVKEDIVNVVSDLAGRIAPDYNIKIHVNTADIPEKNSFYLTVTGTSAEHGDDGATG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC
RGNRANGLIPPMRPISLEATAGKNPVNHVGKIYNVVARRIAERVYEVYNGIFSDVYVELL
CCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQIGKPIDQPLVASVKLIPSDLSMNDIPSHIMSEIHGIADEELTNIKRVTEMVLNDQVTL
HHHCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEE
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]