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The map label for this gene is ubiC [H]

Identifier: 218710911

GI number: 218710911

Start: 3163225

End: 3163779

Strand: Reverse

Name: ubiC [H]

Synonym: VS_3013

Alternate gene names: 218710911

Gene position: 3163779-3163225 (Counterclockwise)

Preceding gene: 218710913

Following gene: 218710910

Centisome position: 95.89

GC content: 42.34

Gene sequence:

>555_bases
TTGAATACTAGTATGAATCAGTCAATATCATTGTATCTAAATTCATTAATGAATGTAGATTGGCAAAGCACAGAAAAATT
TAATTTTCCTAATGAAACCACCAAAGAGTGGCTTATGGAACAAGGATCGCTTTCCCGTAAGTTGGGCAAGTGCTGCAAGC
ACCTGTCTGTTGAGTTGCTTCATAATCAAGTTGTGGAACGATCAATTCTGCAACAGGACGAAGAACGCCTTTTATCATCA
CATGATTGCTTACTGCGTAAAGTGATTTTAAAGGGTGATGATGAGCCGTGGGTGTTAGGTCGAACCTTAATACCTCGAAT
TACCCTAGAAGATCATCAGCACTCTGACCTTTCTCAGCAAGGGGATGTCCCGCTTGGATTAACTGTTTTCAGTGCTGAGA
ATGTGGAGCGAGATGCGCTACAAGTCGGTTGGGTTATCGCTGGTGATGAGCGATTACTCGCGCGTCGTTCTCGATTATGG
ATGAATCATAAACCGATGCTTGTGGCCGAACTTTTTTTACCAACATCCCCCATTTACTCTAAGGAGAGTGTGTAA

Upstream 100 bases:

>100_bases
TGTTACAATGAGCGGTCTAAATCTAAATACGTTTACAATTCGAAGGACGCTTTAATTTTATTCGAAAGTTGAAGCTTTAT
TGTACGTGTAAAGTCACCTA

Downstream 100 bases:

>100_bases
ATGCTTGCCACCAAAGCGAAGGCGTACTGGCAATTGACGCGAATGAATCGCCCGATTGGTACTCTGTTACTCCTTTGGCC
GACCTTGTGGTCGCTGATTA

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNTSMNQSISLYLNSLMNVDWQSTEKFNFPNETTKEWLMEQGSLSRKLGKCCKHLSVELLHNQVVERSILQQDEERLLSS
HDCLLRKVILKGDDEPWVLGRTLIPRITLEDHQHSDLSQQGDVPLGLTVFSAENVERDALQVGWVIAGDERLLARRSRLW
MNHKPMLVAELFLPTSPIYSKESV

Sequences:

>Translated_184_residues
MNTSMNQSISLYLNSLMNVDWQSTEKFNFPNETTKEWLMEQGSLSRKLGKCCKHLSVELLHNQVVERSILQQDEERLLSS
HDCLLRKVILKGDDEPWVLGRTLIPRITLEDHQHSDLSQQGDVPLGLTVFSAENVERDALQVGWVIAGDERLLARRSRLW
MNHKPMLVAELFLPTSPIYSKESV
>Mature_184_residues
MNTSMNQSISLYLNSLMNVDWQSTEKFNFPNETTKEWLMEQGSLSRKLGKCCKHLSVELLHNQVVERSILQQDEERLLSS
HDCLLRKVILKGDDEPWVLGRTLIPRITLEDHQHSDLSQQGDVPLGLTVFSAENVERDALQVGWVIAGDERLLARRSRLW
MNHKPMLVAELFLPTSPIYSKESV

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway [H]

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family [H]

Homologues:

Organism=Escherichia coli, GI87082361, Length=144, Percent_Identity=34.0277777777778, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007440 [H]

Pfam domain/function: PF04345 Chor_lyase [H]

EC number: =4.1.3.40 [H]

Molecular weight: Translated: 21169; Mature: 21169

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSMNQSISLYLNSLMNVDWQSTEKFNFPNETTKEWLMEQGSLSRKLGKCCKHLSVELL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HNQVVERSILQQDEERLLSSHDCLLRKVILKGDDEPWVLGRTLIPRITLEDHQHSDLSQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHCCEEEECCCCCCCCHHC
GDVPLGLTVFSAENVERDALQVGWVIAGDERLLARRSRLWMNHKPMLVAELFLPTSPIYS
CCCCEEEEEEECCCCCHHHHEECEEEECCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
KESV
CCCC
>Mature Secondary Structure
MNTSMNQSISLYLNSLMNVDWQSTEKFNFPNETTKEWLMEQGSLSRKLGKCCKHLSVELL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HNQVVERSILQQDEERLLSSHDCLLRKVILKGDDEPWVLGRTLIPRITLEDHQHSDLSQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHCCEEEECCCCCCCCHHC
GDVPLGLTVFSAENVERDALQVGWVIAGDERLLARRSRLWMNHKPMLVAELFLPTSPIYS
CCCCEEEEEEECCCCCHHHHEECEEEECCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
KESV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]