Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 218710805

GI number: 218710805

Start: 3037459

End: 3038463

Strand: Reverse

Name: argC [H]

Synonym: VS_2888

Alternate gene names: 218710805

Gene position: 3038463-3037459 (Counterclockwise)

Preceding gene: 218710809

Following gene: 218710804

Centisome position: 92.09

GC content: 46.47

Gene sequence:

>1005_bases
ATGTTGAAAACCACGATCATTGGTGCAAGCGGCTATACAGGAGCAGAACTGGCTCTAATGATAAACAGACACCCTGAGCT
CACGCTATCAGGTTTATATGTCTCAGCCAATAGTGTAGATGCGGGCAAACCTATCGCTGCACTGCACGGTAAGTTAGCTG
GCCTGATTGATATGCCAGTACAACCTTTAACAAATCCGGAAGAAGTGGCCAAACAGTCTGATGTGATTTTTCTAGCAACG
GCACACGAAGTCAGTCACGACCTAGCGCCCATTTTTCTAGAGAACGACTGCCAAGTGTTCGACCTATCGGGTGCATTCAG
AGTTAAAGGTGAAAACTTCTATCAAGAGTTTTACGGTTTTGAACATCAACACGAACAATGGCTAGACAAAGCGGCTTACG
GTTTAGCGGAATGGAACGAACAAGAAATCAAAGAAGCTCAGCTTGTTGCGGTAGCGGGTTGTTACCCAACGGCATCACAA
CTGGCGATTAAGCCTTTGGTTGAAGCCGAGTTACTTGATGAGAACCAATGGCCAGTGATTAATGCAACCAGCGGTGTGAC
TGGTGCAGGCCGCAAGGCGACCATAGTTAACAGCTTCTGCGAAGTGAGCCTGCAAGCTTATGGCGTCTTCAATCACCGTC
ATCAACCTGAAATGGCCGCACATTTAGGATGTGATGTAATTTTCACCCCGCACCTCGGCAACTTTAAGCGTGGCATTTTA
GCGACCATCACCATGAAACTGGCTGACGGTGTGACAGAACAACAGATACAAGATGCCTTCGAGCAAGCTTATCAAGGTAA
GCCAGCTGTGAGATTGCTCGAAGAGACATTGCCAAGAATTCAAGATGTAGAACAGACGCCTTTCTGCGACTTAGGTTGGA
AGGTTCAAGGTCAGCACATCATCGTTGTTTCAGCGATTGATAACTTATTAAAGGGTGCATCTAGCCAAGCGATGCAGTGT
TTGAATTTACGTTATGGTTTTGCGCCATTAACTGCGTTAGTGTAA

Upstream 100 bases:

>100_bases
TTAAATCATATTTAATGCATAAGAAATCAAATATAGCTAAAAATTAAGTATGAATAGTCAAATTTGAAATATAACTTACC
TCAAGAATGGATGTGTTGAG

Downstream 100 bases:

>100_bases
GGAAATCTAGATATGAGCCTTAATAATCAACCATTAATCATAAAGTTAGGTGGCGCTGCGCTATCTTGTGGTGAAACACT
TAGCAAGTTATTTGGTGCTA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLKTTIIGASGYTGAELALMINRHPELTLSGLYVSANSVDAGKPIAALHGKLAGLIDMPVQPLTNPEEVAKQSDVIFLAT
AHEVSHDLAPIFLENDCQVFDLSGAFRVKGENFYQEFYGFEHQHEQWLDKAAYGLAEWNEQEIKEAQLVAVAGCYPTASQ
LAIKPLVEAELLDENQWPVINATSGVTGAGRKATIVNSFCEVSLQAYGVFNHRHQPEMAAHLGCDVIFTPHLGNFKRGIL
ATITMKLADGVTEQQIQDAFEQAYQGKPAVRLLEETLPRIQDVEQTPFCDLGWKVQGQHIIVVSAIDNLLKGASSQAMQC
LNLRYGFAPLTALV

Sequences:

>Translated_334_residues
MLKTTIIGASGYTGAELALMINRHPELTLSGLYVSANSVDAGKPIAALHGKLAGLIDMPVQPLTNPEEVAKQSDVIFLAT
AHEVSHDLAPIFLENDCQVFDLSGAFRVKGENFYQEFYGFEHQHEQWLDKAAYGLAEWNEQEIKEAQLVAVAGCYPTASQ
LAIKPLVEAELLDENQWPVINATSGVTGAGRKATIVNSFCEVSLQAYGVFNHRHQPEMAAHLGCDVIFTPHLGNFKRGIL
ATITMKLADGVTEQQIQDAFEQAYQGKPAVRLLEETLPRIQDVEQTPFCDLGWKVQGQHIIVVSAIDNLLKGASSQAMQC
LNLRYGFAPLTALV
>Mature_334_residues
MLKTTIIGASGYTGAELALMINRHPELTLSGLYVSANSVDAGKPIAALHGKLAGLIDMPVQPLTNPEEVAKQSDVIFLAT
AHEVSHDLAPIFLENDCQVFDLSGAFRVKGENFYQEFYGFEHQHEQWLDKAAYGLAEWNEQEIKEAQLVAVAGCYPTASQ
LAIKPLVEAELLDENQWPVINATSGVTGAGRKATIVNSFCEVSLQAYGVFNHRHQPEMAAHLGCDVIFTPHLGNFKRGIL
ATITMKLADGVTEQQIQDAFEQAYQGKPAVRLLEETLPRIQDVEQTPFCDLGWKVQGQHIIVVSAIDNLLKGASSQAMQC
LNLRYGFAPLTALV

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=334, Percent_Identity=61.6766467065868, Blast_Score=436, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6320913, Length=339, Percent_Identity=28.023598820059, Blast_Score=115, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 36516; Mature: 36516

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01224 ARGC ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTTIIGASGYTGAELALMINRHPELTLSGLYVSANSVDAGKPIAALHGKLAGLIDMPV
CCEEEEEECCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
QPLTNPEEVAKQSDVIFLATAHEVSHDLAPIFLENDCQVFDLSGAFRVKGENFYQEFYGF
CCCCCHHHHHCCCCEEEEEEHHHHCCCCCCEEECCCCEEEECCCEEEECCHHHHHHHCCC
EHQHEQWLDKAAYGLAEWNEQEIKEAQLVAVAGCYPTASQLAIKPLVEAELLDENQWPVI
CHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEE
NATSGVTGAGRKATIVNSFCEVSLQAYGVFNHRHQPEMAAHLGCDVIFTPHLGNFKRGIL
ECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCCEEECCCCCCCHHHHH
ATITMKLADGVTEQQIQDAFEQAYQGKPAVRLLEETLPRIQDVEQTPFCDLGWKVQGQHI
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCEE
IVVSAIDNLLKGASSQAMQCLNLRYGFAPLTALV
EEEHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MLKTTIIGASGYTGAELALMINRHPELTLSGLYVSANSVDAGKPIAALHGKLAGLIDMPV
CCEEEEEECCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
QPLTNPEEVAKQSDVIFLATAHEVSHDLAPIFLENDCQVFDLSGAFRVKGENFYQEFYGF
CCCCCHHHHHCCCCEEEEEEHHHHCCCCCCEEECCCCEEEECCCEEEECCHHHHHHHCCC
EHQHEQWLDKAAYGLAEWNEQEIKEAQLVAVAGCYPTASQLAIKPLVEAELLDENQWPVI
CHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEE
NATSGVTGAGRKATIVNSFCEVSLQAYGVFNHRHQPEMAAHLGCDVIFTPHLGNFKRGIL
ECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCCEEECCCCCCCHHHHH
ATITMKLADGVTEQQIQDAFEQAYQGKPAVRLLEETLPRIQDVEQTPFCDLGWKVQGQHI
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCEE
IVVSAIDNLLKGASSQAMQCLNLRYGFAPLTALV
EEEHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]