Click here to switch to the map view.

The map label for this gene is pilQ [H]

Identifier: 218710790

GI number: 218710790

Start: 3020875

End: 3022593

Strand: Reverse

Name: pilQ [H]

Synonym: VS_2873

Alternate gene names: 218710790

Gene position: 3022593-3020875 (Counterclockwise)

Preceding gene: 218710791

Following gene: 218710789

Centisome position: 91.61

GC content: 44.21

Gene sequence:

>1719_bases
ATGATTAAAGGAATAAGTGGATTAGTGAGCAAGGCTCTACAAGGTTTTGCTGTGTCTGTGATGTTGGTGGTTAGCGTGTT
CAGCTATGCCGAGAGCTTGCCAAATCAATTGGAAAATATTGATTTTAGGGTCAACAAGGAGAAAGACGCCGTCATCATTA
TCGAATTGGCAACCAGCACTGCTGTGGTGGATGTTCAACGTGCTCAGGAAGGTTTAAGTATCGAGTTACTCAATACTCAG
GTGAATGACGATAAGCTTTACCTCCTAGATGTGAAGGACTTCGCGACCTCAGTTGAAGGCATTGAGGTGTATAAGGAAAC
GCCCAGTACGCGATTGTTGGCAACGATCGCTGGTGACTATCAATATGAATACAACTTAAAAGGTCGCTTTATTGAGGTAG
TGATCAGTAGGCCTACTATTGATGAAGTGACAATAGAGAAAAATGTTTTAGAAAAAGAAGGCAAGGTGATATCGATTAAC
TTCCAAGATATCCCTGTACGTAATGTTTTGCAGCTTATTGCTGATTACAACGATTTCAATCTCGTTGTTTCTGATTCAGT
CACGGGTAATCTGACTTTACGTTTAGATGGTGTGCCTTGGCAGCAAGTTCTCGACATTATCTTGCAAGTTAAGGGGTTGG
ATAAGCGTGTTGATGGCAACGTTATCTTGGTGGCACCTAAAGCTGAACTCGACCTTAGAGAGCAACAAGCGCTAGAGAAA
TCTCGTTTGGAAGAAGAGCTAGGTGAACTCAAGTCGGAAATCATCAAGATTAACTTTGCCAAAGCCACCGACATTGCCGA
CATGATTGGTGGGGAAGGGGCGGTAAGCATGTTGTCCGAGCGAGGCTCGATTACCATTGATGAGCGAACTAACTCCCTGT
TGATCCGTGAATTGGAAGAAAACATTGCGGTGATACGAGGCATTATTGAATCGCTAGACATTCCCGTGAAGCAAGTTCAG
ATAGAAGCACGTATTGTCACTGTTACTGAGGGTAATCTTGATGAACTAGGAGTGCGTTGGGGCGTTTCCTCGACTAACGG
AAGCTTCAAAGTTGGCGGCTCGATAGAGGGCAACCATCCATCGCAAATTACGCCGTATGACGATAATGGTGGGAATAGTG
CGATTGACGATTTCCTCAACGTTAATTTAGGAGCAACTTCCCCGAGCGCGTCGAGTATTGCGTTTCAGGTAGCCAAGCTG
GGTTCTGATACCTTGCTCGATCTTGAATTGTCAGCACTGCAACAAGAGTCGAAAGCAGAGATTATTTCTAGCCCACGCTT
AATTACCACCAATAAAAAACCCGCTTATATTGAGCAAGGTACTGAAATCCCTTATTTAGAGTCTTCTTCAAGTGGTGCTA
CTTCAGTCGCATTTAAGAAAGCGGTATTGAGTCTCAAGGTGACTCCGCAGATCACACCCGACAATCGTTTGGTATTGGAT
TTGAGCGTGACTCAAGATAGGCCGGGGCAAGTGGTGAAAACCGGCACCGGTGAAGCTGTCGCCATTGACACGCAAAGAAT
TGGAACGCAAGTGCTTGTTAATAATGGTGAAACGGTCGTGTTAGGTGGTATTTTTCAACACAGTGTGAGCAGCCAAGTTG
ATAAAGTTCCACTATTAGGAGACCTTCCTGTTCTTGGCGCATTGTTCCGTCGTAGCTATGAAAATGTAGGCAAAAGTGAA
CTACTTATTTTTGTTACACCTAAAGTTGTGATTCAGTAA

Upstream 100 bases:

>100_bases
ATGAAACTCTTCCAGATGGTTTAGGTTGTTGGCATAAACGCAACGTTAGGCTCGCTCTGAAGTAAACCAATGTCACATGA
TGTGGATATGAGATGTAAAT

Downstream 100 bases:

>100_bases
TGAGCAATTAGATTAAAAATAAAGTTGCATTAGTGGCACCTAACCTTGATAATTTCGGGTCTTATCACGAATTATCTGTG
AGGAATCGGTGCCACGGGCC

Product: type IV pilus assembly protein PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MIKGISGLVSKALQGFAVSVMLVVSVFSYAESLPNQLENIDFRVNKEKDAVIIIELATSTAVVDVQRAQEGLSIELLNTQ
VNDDKLYLLDVKDFATSVEGIEVYKETPSTRLLATIAGDYQYEYNLKGRFIEVVISRPTIDEVTIEKNVLEKEGKVISIN
FQDIPVRNVLQLIADYNDFNLVVSDSVTGNLTLRLDGVPWQQVLDIILQVKGLDKRVDGNVILVAPKAELDLREQQALEK
SRLEEELGELKSEIIKINFAKATDIADMIGGEGAVSMLSERGSITIDERTNSLLIRELEENIAVIRGIIESLDIPVKQVQ
IEARIVTVTEGNLDELGVRWGVSSTNGSFKVGGSIEGNHPSQITPYDDNGGNSAIDDFLNVNLGATSPSASSIAFQVAKL
GSDTLLDLELSALQQESKAEIISSPRLITTNKKPAYIEQGTEIPYLESSSSGATSVAFKKAVLSLKVTPQITPDNRLVLD
LSVTQDRPGQVVKTGTGEAVAIDTQRIGTQVLVNNGETVVLGGIFQHSVSSQVDKVPLLGDLPVLGALFRRSYENVGKSE
LLIFVTPKVVIQ

Sequences:

>Translated_572_residues
MIKGISGLVSKALQGFAVSVMLVVSVFSYAESLPNQLENIDFRVNKEKDAVIIIELATSTAVVDVQRAQEGLSIELLNTQ
VNDDKLYLLDVKDFATSVEGIEVYKETPSTRLLATIAGDYQYEYNLKGRFIEVVISRPTIDEVTIEKNVLEKEGKVISIN
FQDIPVRNVLQLIADYNDFNLVVSDSVTGNLTLRLDGVPWQQVLDIILQVKGLDKRVDGNVILVAPKAELDLREQQALEK
SRLEEELGELKSEIIKINFAKATDIADMIGGEGAVSMLSERGSITIDERTNSLLIRELEENIAVIRGIIESLDIPVKQVQ
IEARIVTVTEGNLDELGVRWGVSSTNGSFKVGGSIEGNHPSQITPYDDNGGNSAIDDFLNVNLGATSPSASSIAFQVAKL
GSDTLLDLELSALQQESKAEIISSPRLITTNKKPAYIEQGTEIPYLESSSSGATSVAFKKAVLSLKVTPQITPDNRLVLD
LSVTQDRPGQVVKTGTGEAVAIDTQRIGTQVLVNNGETVVLGGIFQHSVSSQVDKVPLLGDLPVLGALFRRSYENVGKSE
LLIFVTPKVVIQ
>Mature_572_residues
MIKGISGLVSKALQGFAVSVMLVVSVFSYAESLPNQLENIDFRVNKEKDAVIIIELATSTAVVDVQRAQEGLSIELLNTQ
VNDDKLYLLDVKDFATSVEGIEVYKETPSTRLLATIAGDYQYEYNLKGRFIEVVISRPTIDEVTIEKNVLEKEGKVISIN
FQDIPVRNVLQLIADYNDFNLVVSDSVTGNLTLRLDGVPWQQVLDIILQVKGLDKRVDGNVILVAPKAELDLREQQALEK
SRLEEELGELKSEIIKINFAKATDIADMIGGEGAVSMLSERGSITIDERTNSLLIRELEENIAVIRGIIESLDIPVKQVQ
IEARIVTVTEGNLDELGVRWGVSSTNGSFKVGGSIEGNHPSQITPYDDNGGNSAIDDFLNVNLGATSPSASSIAFQVAKL
GSDTLLDLELSALQQESKAEIISSPRLITTNKKPAYIEQGTEIPYLESSSSGATSVAFKKAVLSLKVTPQITPDNRLVLD
LSVTQDRPGQVVKTGTGEAVAIDTQRIGTQVLVNNGETVVLGGIFQHSVSSQVDKVPLLGDLPVLGALFRRSYENVGKSE
LLIFVTPKVVIQ

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=417, Percent_Identity=38.6091127098321, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI87082242, Length=383, Percent_Identity=30.5483028720627, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 62145; Mature: 62145

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKGISGLVSKALQGFAVSVMLVVSVFSYAESLPNQLENIDFRVNKEKDAVIIIELATST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCEEEEEEECCCE
AVVDVQRAQEGLSIELLNTQVNDDKLYLLDVKDFATSVEGIEVYKETPSTRLLATIAGDY
EEEEHHHHHCCCEEEEEEEECCCCEEEEEEEHHHHCCCCCEEEEECCCCCEEEEEEECCE
QYEYNLKGRFIEVVISRPTIDEVTIEKNVLEKEGKVISINFQDIPVRNVLQLIADYNDFN
EEEEECCCEEEEEEEECCCCCCEEEHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCE
LVVSDSVTGNLTLRLDGVPWQQVLDIILQVKGLDKRVDGNVILVAPKAELDLREQQALEK
EEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHH
SRLEEELGELKSEIIKINFAKATDIADMIGGEGAVSMLSERGSITIDERTNSLLIRELEE
HHHHHHHHHHHHHEEEEEECCCCCHHHHHCCCHHHHHHHCCCCEEEECCCCHHHHHHHHH
NIAVIRGIIESLDIPVKQVQIEARIVTVTEGNLDELGVRWGVSSTNGSFKVGGSIEGNHP
HHHHHHHHHHHCCCCHHHEEEEEEEEEEECCCHHHCCEEECCCCCCCCEEECCEECCCCC
SQITPYDDNGGNSAIDDFLNVNLGATSPSASSIAFQVAKLGSDTLLDLELSALQQESKAE
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCEEEEEEHHHHHHHHHHH
IISSPRLITTNKKPAYIEQGTEIPYLESSSSGATSVAFKKAVLSLKVTPQITPDNRLVLD
HHCCCEEEECCCCCCEEECCCCCCEEECCCCCCHHHHEEEEEEEEEECCEECCCCEEEEE
LSVTQDRPGQVVKTGTGEAVAIDTQRIGTQVLVNNGETVVLGGIFQHSVSSQVDKVPLLG
EEECCCCCCCEEEECCCCEEEEEHHHCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCCCC
DLPVLGALFRRSYENVGKSELLIFVTPKVVIQ
CCHHHHHHHHHHHHCCCCCEEEEEECCEEEEC
>Mature Secondary Structure
MIKGISGLVSKALQGFAVSVMLVVSVFSYAESLPNQLENIDFRVNKEKDAVIIIELATST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCEEEEEEECCCE
AVVDVQRAQEGLSIELLNTQVNDDKLYLLDVKDFATSVEGIEVYKETPSTRLLATIAGDY
EEEEHHHHHCCCEEEEEEEECCCCEEEEEEEHHHHCCCCCEEEEECCCCCEEEEEEECCE
QYEYNLKGRFIEVVISRPTIDEVTIEKNVLEKEGKVISINFQDIPVRNVLQLIADYNDFN
EEEEECCCEEEEEEEECCCCCCEEEHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCE
LVVSDSVTGNLTLRLDGVPWQQVLDIILQVKGLDKRVDGNVILVAPKAELDLREQQALEK
EEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHH
SRLEEELGELKSEIIKINFAKATDIADMIGGEGAVSMLSERGSITIDERTNSLLIRELEE
HHHHHHHHHHHHHEEEEEECCCCCHHHHHCCCHHHHHHHCCCCEEEECCCCHHHHHHHHH
NIAVIRGIIESLDIPVKQVQIEARIVTVTEGNLDELGVRWGVSSTNGSFKVGGSIEGNHP
HHHHHHHHHHHCCCCHHHEEEEEEEEEEECCCHHHCCEEECCCCCCCCEEECCEECCCCC
SQITPYDDNGGNSAIDDFLNVNLGATSPSASSIAFQVAKLGSDTLLDLELSALQQESKAE
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCEEEEEEHHHHHHHHHHH
IISSPRLITTNKKPAYIEQGTEIPYLESSSSGATSVAFKKAVLSLKVTPQITPDNRLVLD
HHCCCEEEECCCCCCEEECCCCCCEEECCCCCCHHHHEEEEEEEEEECCEECCCCEEEEE
LSVTQDRPGQVVKTGTGEAVAIDTQRIGTQVLVNNGETVVLGGIFQHSVSSQVDKVPLLG
EEECCCCCCCEEEECCCCEEEEEHHHCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCCCC
DLPVLGALFRRSYENVGKSELLIFVTPKVVIQ
CCHHHHHHHHHHHHCCCCCEEEEEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]