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The map label for this gene is trpS [H]

Identifier: 218710783

GI number: 218710783

Start: 3013690

End: 3014712

Strand: Reverse

Name: trpS [H]

Synonym: VS_2866

Alternate gene names: 218710783

Gene position: 3014712-3013690 (Counterclockwise)

Preceding gene: 218710784

Following gene: 218710781

Centisome position: 91.37

GC content: 47.02

Gene sequence:

>1023_bases
ATGAGCAAGCCCATCGTATTGAGTGGTGTTCAACCATCTGGTGAACTAAGTATCGGTAACTACTTGGGTGCTCTACGTCA
ATGGCAACAGATGCAAGATGATTACGATTGCCAATACTGTGTTGTAGACCTTCACGCAATTACGGTTCGCCAAGATCCGA
AAGCACTGCATGAAGCGACTCTAGATGCATTAGCAATCTGTCTTGCTGTCGGTGTTGATCCAAAGAAGAGCACGCTATTT
GTTCAGTCACACGTACCAGAGCATGCTCAACTTGGTTGGCTTCTTAACTGTTACACGCAAATGGGTGAACTGAGCCGTAT
GACTCAGTTTAAAGATAAGTCTGCACGTCACTCAAACGACGTAAACGTAGGACTATACGACTACCCAGTGTTGATGGCTG
CAGACATCCTGCTTTACGGTGCTCACCAAGTGCCAGTAGGTAGCGACCAGAAACAACACTTAGAGCTAGCGCGTGATATC
GCAACTCGCTTTAACAACATTTACGGTCCTGAAACGCCAATCTTCCAAGTACCAGAACCTTACATTCCAACAGTGAATGC
ACGTGTAATGAGCCTGCAAGATGCGACGAAGAAGATGTCTAAGTCGGATGACAACCGTAAGAACGTGATTACTCTGCTAG
AAGAGCCTAAGTCGATCATCAAGAAGATCAACAAAGCGCAAACCGATGCAGAAACGCCACCACGTATTGCTCACGATTGG
GAAAACAAAGCAGGTATCTCTAACCTAATGGGTCTTTACTCTGCGGCGACGGGTAAAACGTTTGAAGAGATCGAAGCGCA
GTACCAAGGCGTTGAAATGTACGGTCCATTTAAGAAAGATGTAGGCGCAGCATTGGTTGAGATGCTTGAGCCGATTCAAT
CTGAATACCACCGTATCCGTGCTGACCGTGCTTACATGGACGCAGTAATGAAAGCGGGTGCGGGTGCCGAAAAAGCCTCT
GAGCGTGCTGCAGTAACACTGAAAAAAGCATACGAAGCGGTAGGTTTTGTTACTCGCCCATAG

Upstream 100 bases:

>100_bases
GTACGGCTTTCTATTTTAAAGTTAAGAAGCTAAGTTTTTCAGATACTAGGTTAAGAAACTAAGTTAACGAGCTTAGCTAA
CAAGCAAAGGAATTAAAACC

Downstream 100 bases:

>100_bases
GGTTTACTAAAACGACTCGTTTAGAAATTCAAGCCCAAAGTGACTTTGTTTACTTTGGGCTTTTTATTGCCCGCTCCATT
TACCTTCCCAGTAAATCTCT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEATLDALAICLAVGVDPKKSTLF
VQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSNDVNVGLYDYPVLMAADILLYGAHQVPVGSDQKQHLELARDI
ATRFNNIYGPETPIFQVPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLLEEPKSIIKKINKAQTDAETPPRIAHDW
ENKAGISNLMGLYSAATGKTFEEIEAQYQGVEMYGPFKKDVGAALVEMLEPIQSEYHRIRADRAYMDAVMKAGAGAEKAS
ERAAVTLKKAYEAVGFVTRP

Sequences:

>Translated_340_residues
MSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEATLDALAICLAVGVDPKKSTLF
VQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSNDVNVGLYDYPVLMAADILLYGAHQVPVGSDQKQHLELARDI
ATRFNNIYGPETPIFQVPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLLEEPKSIIKKINKAQTDAETPPRIAHDW
ENKAGISNLMGLYSAATGKTFEEIEAQYQGVEMYGPFKKDVGAALVEMLEPIQSEYHRIRADRAYMDAVMKAGAGAEKAS
ERAAVTLKKAYEAVGFVTRP
>Mature_339_residues
SKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEATLDALAICLAVGVDPKKSTLFV
QSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSNDVNVGLYDYPVLMAADILLYGAHQVPVGSDQKQHLELARDIA
TRFNNIYGPETPIFQVPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLLEEPKSIIKKINKAQTDAETPPRIAHDWE
NKAGISNLMGLYSAATGKTFEEIEAQYQGVEMYGPFKKDVGAALVEMLEPIQSEYHRIRADRAYMDAVMKAGAGAEKASE
RAAVTLKKAYEAVGFVTRP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=337, Percent_Identity=40.6528189910979, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=51.3966480446927, Blast_Score=188, Evalue=6e-48,
Organism=Escherichia coli, GI1789786, Length=340, Percent_Identity=64.7058823529412, Blast_Score=460, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI71982800, Length=340, Percent_Identity=35, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71982793, Length=340, Percent_Identity=35, Blast_Score=194, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6320474, Length=354, Percent_Identity=38.7005649717514, Blast_Score=221, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24666151, Length=335, Percent_Identity=42.6865671641791, Blast_Score=244, Evalue=8e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37788; Mature: 37656

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEAT
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHH
LDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSND
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNVGLYDYPVLMAADILLYGAHQVPVGSDQKQHLELARDIATRFNNIYGPETPIFQVPEP
CEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCC
YIPTVNARVMSLQDATKKMSKSDDNRKNVITLLEEPKSIIKKINKAQTDAETPPRIAHDW
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
ENKAGISNLMGLYSAATGKTFEEIEAQYQGVEMYGPFKKDVGAALVEMLEPIQSEYHRIR
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADRAYMDAVMKAGAGAEKASERAAVTLKKAYEAVGFVTRP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEAT
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHH
LDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSND
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNVGLYDYPVLMAADILLYGAHQVPVGSDQKQHLELARDIATRFNNIYGPETPIFQVPEP
CEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCC
YIPTVNARVMSLQDATKKMSKSDDNRKNVITLLEEPKSIIKKINKAQTDAETPPRIAHDW
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
ENKAGISNLMGLYSAATGKTFEEIEAQYQGVEMYGPFKKDVGAALVEMLEPIQSEYHRIR
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADRAYMDAVMKAGAGAEKASERAAVTLKKAYEAVGFVTRP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA