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The map label for this gene is mlaC [H]

Identifier: 218710667

GI number: 218710667

Start: 2913629

End: 2914366

Strand: Reverse

Name: mlaC [H]

Synonym: VS_2747

Alternate gene names: 218710667

Gene position: 2914366-2913629 (Counterclockwise)

Preceding gene: 218710668

Following gene: 218710666

Centisome position: 88.33

GC content: 40.51

Gene sequence:

>738_bases
TTGGCCAAGTGCTGTATAGCGTTGGTGGTTCTAATGACAGTGAAGCAAAGGAATAAGATGATGTTGAAAACTATTAGTCA
CTTGAAAGCTATTGGTTACTTGAAATCAATGTTTATGGCGGCAATGGCTTTACTTATTTCGGCTCAAGCTTTTGCTGCAG
AGTCGATTGATCGTACTCAGCCATACCAGATGATGACTCAAGTTGCAGAAGAGGCTTTCGCCCGTTTGAAGAACGAGCAA
GAGAATATCCATCAAGATCCTGAGTTACTGAAGGTCATCGTGGAAGAAGAGTTGATGCCTTATGTTAATGCTCAATATGC
GGCGCTGAAGTTGCTAGGGCCGAACTTGAAAGGTGCTGATAGAGGAGACGTGCGCGTATTTATTGATGCATTTCGTAAAT
ATCTCGTTTCTTCTTATGCTCAAGTGTTAACTCAATATACAGATCAGACGATTAAATTTGGTCCAGAACCAACAATTAAA
ACAGATAGCCGTATTACCAGTATTAAGGTTGATATCATTGATACGCCTCGACCAAACATTAACCTTGAGTTTAAACTGCG
CAAAGATAAGAAGTCAGGTGAGTGGAAGGCATTTGATATGGTTGCCGAAGGTATAAGCCTGCTATCAAGTAAGAAATCTG
AGTGGAACACTAAGATTCGTCAAGAAGGCATCTTACAAGTAGCTGAAGAACTCGAGAAACTGGCTTCTCAACCGATTCGT
TTTGAGAGTAATAAATAA

Upstream 100 bases:

>100_bases
ATCAGCTTAGTTCCAGGCTTCATCTTTGAAGATGAAGAGATGTTGGTTGATGGTGATTCTATCGAAGACACCAAGTCAGC
ATTAGTATTAGAAGATTTGA

Downstream 100 bases:

>100_bases
TGAGCCATTCTCAATGGCAAGCGCTAAGCTCTAAAGAGTATCAGCTGCTCGGTGATATCGACCGAGACAGCGTTCCTGCA
ATCTGGCGTATATTGGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MAKCCIALVVLMTVKQRNKMMLKTISHLKAIGYLKSMFMAAMALLISAQAFAAESIDRTQPYQMMTQVAEEAFARLKNEQ
ENIHQDPELLKVIVEEELMPYVNAQYAALKLLGPNLKGADRGDVRVFIDAFRKYLVSSYAQVLTQYTDQTIKFGPEPTIK
TDSRITSIKVDIIDTPRPNINLEFKLRKDKKSGEWKAFDMVAEGISLLSSKKSEWNTKIRQEGILQVAEELEKLASQPIR
FESNK

Sequences:

>Translated_245_residues
MAKCCIALVVLMTVKQRNKMMLKTISHLKAIGYLKSMFMAAMALLISAQAFAAESIDRTQPYQMMTQVAEEAFARLKNEQ
ENIHQDPELLKVIVEEELMPYVNAQYAALKLLGPNLKGADRGDVRVFIDAFRKYLVSSYAQVLTQYTDQTIKFGPEPTIK
TDSRITSIKVDIIDTPRPNINLEFKLRKDKKSGEWKAFDMVAEGISLLSSKKSEWNTKIRQEGILQVAEELEKLASQPIR
FESNK
>Mature_244_residues
AKCCIALVVLMTVKQRNKMMLKTISHLKAIGYLKSMFMAAMALLISAQAFAAESIDRTQPYQMMTQVAEEAFARLKNEQE
NIHQDPELLKVIVEEELMPYVNAQYAALKLLGPNLKGADRGDVRVFIDAFRKYLVSSYAQVLTQYTDQTIKFGPEPTIKT
DSRITSIKVDIIDTPRPNINLEFKLRKDKKSGEWKAFDMVAEGISLLSSKKSEWNTKIRQEGILQVAEELEKLASQPIRF
ESNK

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=205, Percent_Identity=40, Blast_Score=167, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 27854; Mature: 27723

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKCCIALVVLMTVKQRNKMMLKTISHLKAIGYLKSMFMAAMALLISAQAFAAESIDRTQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PYQMMTQVAEEAFARLKNEQENIHQDPELLKVIVEEELMPYVNAQYAALKLLGPNLKGAD
HHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
RGDVRVFIDAFRKYLVSSYAQVLTQYTDQTIKFGPEPTIKTDSRITSIKVDIIDTPRPNI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEEEEEECCCCCC
NLEFKLRKDKKSGEWKAFDMVAEGISLLSSKKSEWNTKIRQEGILQVAEELEKLASQPIR
EEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FESNK
CCCCC
>Mature Secondary Structure 
AKCCIALVVLMTVKQRNKMMLKTISHLKAIGYLKSMFMAAMALLISAQAFAAESIDRTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PYQMMTQVAEEAFARLKNEQENIHQDPELLKVIVEEELMPYVNAQYAALKLLGPNLKGAD
HHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
RGDVRVFIDAFRKYLVSSYAQVLTQYTDQTIKFGPEPTIKTDSRITSIKVDIIDTPRPNI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEEEEEECCCCCC
NLEFKLRKDKKSGEWKAFDMVAEGISLLSSKKSEWNTKIRQEGILQVAEELEKLASQPIR
EEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FESNK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]