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The map label for this gene is mcp4 [H]

Identifier: 218710642

GI number: 218710642

Start: 2882094

End: 2883719

Strand: Direct

Name: mcp4 [H]

Synonym: VS_2703

Alternate gene names: 218710642

Gene position: 2882094-2883719 (Clockwise)

Preceding gene: 218710640

Following gene: 218710646

Centisome position: 87.35

GC content: 42.74

Gene sequence:

>1626_bases
ATGAAATTAAAAACGCAAGCTTATTTATTATCAGGCATCATTTTGATTGCCTTGCTCGCACTTACGGCTACAGGTTTATG
GACCTTAAGAGTTGCTAGCAACATAGACAACAAAGCTCGCGTGACAGAGCTATTTAAAAGTGCATACAGCATTCTTACTG
AAGTCGAAAAAATGGCTATTGATGGCACTCTAGAAGAACAACAAGCCAAACAGCTGGCCACTCGCCTACTGCGCAACAAT
ATCTATAAAGACAATGAATATGTATATGTTGCTGATGAAGATATGACTTTTGTCGCAACACCTTTAGATCCGCAACTACA
CGGAACCAGCTTTAATGATTTTAAAGATGGCGATGGAAATAGCGTTGGCCAACTTATTCAGCGAGCACTTGGCAATAGAA
CAGGACAAATAGTCGAATACACCTGGACACAAAAACTCCCCGACGGAAGCATTGAAGAAAAACTGTCCATCGCAGAAAAA
ACACCTCATTGGGGTTGGGTTGTAGGTACAGGTATCGGCTTCAATGAAGTCAACGCAAGGTTTTGGTCAACAGCACAATG
GCAACTGATTTTATGTTTGGCTATTGCTGGTGTCATTCTTTCAAGCTTGATTATCTCAATTAAACGTATGCTATCTCTAC
TTGGCGGTGAACCAAAAGATGTAAGAGAAGCAGTACAAGCTGTCGCAAAAGGAAAAATCCAAACATCGTTCGAGACTCAA
GCAGAACAAGGTAGTATCTACCACGCAGTACAACAAATGAGTCAATCACTGGCAGAGTTAGTATCAAACCTTAACTCTTC
AATGTTGGCATTAAGAGGCGAATTACAGCGCGTAGAAGATCGTGCAGGTTCTATCGCTCAACTGACTGAAACTCAGCAAC
AATCAACTGAAATGATCGCAACAGCAATGACCGAGATGGCGTCTTCAGCAAATAATGTTGCTGATTCAGCTGGCGATACT
GCACGTAACACCGACGAGGCCGACAAGCAAAGCCAACATACTCAGCTCCTAATTCACAACACAGTAGATAATATTCAAGG
CCTAGCAGGACAGTTAGGTACAGCGAGTGAAGCTGTCGCTAACCTAGATAACGACGTAAACAATATTGTAAAAGTACTGG
ACGTTATAGGTGATATCGCAGAGCAAACTAACCTGCTAGCACTTAACGCTGCTATCGAGGCTGCACGAGCAGGTGAGCAA
GGTCGCGGCTTTGCTGTAGTGGCAGATGAGGTGCGTAATCTTGCTGGTCGAACGCAATCAAGCACCAAAGAAATTCAGTT
AATGATCAATAACCTTCAAGAAGGCTCCCGCAACGCAATTCAAACGATGAATGTATGTGCTGCAACGAGTGAAAGCACTG
TGACTGAGTCTCAGAATGCCTCTGAAGCCTTACAACAGATTGTGATTGCATTAGAGTCTATATCATCAATGAGCCATCAA
ATCGCAACAGCAGCCGCTGAACAGACCCAGGTAAGCGATGATATATCGAAGCGTATCAATATGATTGAAGAAAGCGGCAA
CCAACTGAGTGATGTCGTAACGGAAAGCCATAACAGTACTCAAACTTTAGCTTCTCTTTCTAACGAATTAGAGACTTGGG
TAAATAGGTTTGAAGTAAAACACTAA

Upstream 100 bases:

>100_bases
ATCATGTTTTGATACCTTTCTGATACCTGCACTACACGACTTAGCTTAAGATTCGTGAATGATACACCATACTTATTATT
AGATCGCTGCACGGGGAAAT

Downstream 100 bases:

>100_bases
ACTCTCGAGAAAAACCTTTAATATAAAAGCACGTTTTCATACGTGCTTTTTTTTATTTCAGCGCTCATTCAAAGCAGTTA
ACCGTAGTTTTGCCATCTTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MKLKTQAYLLSGIILIALLALTATGLWTLRVASNIDNKARVTELFKSAYSILTEVEKMAIDGTLEEQQAKQLATRLLRNN
IYKDNEYVYVADEDMTFVATPLDPQLHGTSFNDFKDGDGNSVGQLIQRALGNRTGQIVEYTWTQKLPDGSIEEKLSIAEK
TPHWGWVVGTGIGFNEVNARFWSTAQWQLILCLAIAGVILSSLIISIKRMLSLLGGEPKDVREAVQAVAKGKIQTSFETQ
AEQGSIYHAVQQMSQSLAELVSNLNSSMLALRGELQRVEDRAGSIAQLTETQQQSTEMIATAMTEMASSANNVADSAGDT
ARNTDEADKQSQHTQLLIHNTVDNIQGLAGQLGTASEAVANLDNDVNNIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRNLAGRTQSSTKEIQLMINNLQEGSRNAIQTMNVCAATSESTVTESQNASEALQQIVIALESISSMSHQ
IATAAAEQTQVSDDISKRINMIEESGNQLSDVVTESHNSTQTLASLSNELETWVNRFEVKH

Sequences:

>Translated_541_residues
MKLKTQAYLLSGIILIALLALTATGLWTLRVASNIDNKARVTELFKSAYSILTEVEKMAIDGTLEEQQAKQLATRLLRNN
IYKDNEYVYVADEDMTFVATPLDPQLHGTSFNDFKDGDGNSVGQLIQRALGNRTGQIVEYTWTQKLPDGSIEEKLSIAEK
TPHWGWVVGTGIGFNEVNARFWSTAQWQLILCLAIAGVILSSLIISIKRMLSLLGGEPKDVREAVQAVAKGKIQTSFETQ
AEQGSIYHAVQQMSQSLAELVSNLNSSMLALRGELQRVEDRAGSIAQLTETQQQSTEMIATAMTEMASSANNVADSAGDT
ARNTDEADKQSQHTQLLIHNTVDNIQGLAGQLGTASEAVANLDNDVNNIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRNLAGRTQSSTKEIQLMINNLQEGSRNAIQTMNVCAATSESTVTESQNASEALQQIVIALESISSMSHQ
IATAAAEQTQVSDDISKRINMIEESGNQLSDVVTESHNSTQTLASLSNELETWVNRFEVKH
>Mature_541_residues
MKLKTQAYLLSGIILIALLALTATGLWTLRVASNIDNKARVTELFKSAYSILTEVEKMAIDGTLEEQQAKQLATRLLRNN
IYKDNEYVYVADEDMTFVATPLDPQLHGTSFNDFKDGDGNSVGQLIQRALGNRTGQIVEYTWTQKLPDGSIEEKLSIAEK
TPHWGWVVGTGIGFNEVNARFWSTAQWQLILCLAIAGVILSSLIISIKRMLSLLGGEPKDVREAVQAVAKGKIQTSFETQ
AEQGSIYHAVQQMSQSLAELVSNLNSSMLALRGELQRVEDRAGSIAQLTETQQQSTEMIATAMTEMASSANNVADSAGDT
ARNTDEADKQSQHTQLLIHNTVDNIQGLAGQLGTASEAVANLDNDVNNIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRNLAGRTQSSTKEIQLMINNLQEGSRNAIQTMNVCAATSESTVTESQNASEALQQIVIALESISSMSHQ
IATAAAEQTQVSDDISKRINMIEESGNQLSDVVTESHNSTQTLASLSNELETWVNRFEVKH

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=322, Percent_Identity=29.8136645962733, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI2367378, Length=406, Percent_Identity=27.3399014778325, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788194, Length=249, Percent_Identity=31.7269076305221, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787690, Length=302, Percent_Identity=29.8013245033113, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=27.2, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58725; Mature: 58725

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKTQAYLLSGIILIALLALTATGLWTLRVASNIDNKARVTELFKSAYSILTEVEKMAI
CCCCHHHHHHHHHHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DGTLEEQQAKQLATRLLRNNIYKDNEYVYVADEDMTFVATPLDPQLHGTSFNDFKDGDGN
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCC
SVGQLIQRALGNRTGQIVEYTWTQKLPDGSIEEKLSIAEKTPHWGWVVGTGIGFNEVNAR
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHCHH
FWSTAQWQLILCLAIAGVILSSLIISIKRMLSLLGGEPKDVREAVQAVAKGKIQTSFETQ
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHH
AEQGSIYHAVQQMSQSLAELVSNLNSSMLALRGELQRVEDRAGSIAQLTETQQQSTEMIA
HHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TAMTEMASSANNVADSAGDTARNTDEADKQSQHTQLLIHNTVDNIQGLAGQLGTASEAVA
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHHCCCCHHHHHH
NLDNDVNNIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQS
HCCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCC
STKEIQLMINNLQEGSRNAIQTMNVCAATSESTVTESQNASEALQQIVIALESISSMSHQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IATAAAEQTQVSDDISKRINMIEESGNQLSDVVTESHNSTQTLASLSNELETWVNRFEVK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
H
C
>Mature Secondary Structure
MKLKTQAYLLSGIILIALLALTATGLWTLRVASNIDNKARVTELFKSAYSILTEVEKMAI
CCCCHHHHHHHHHHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DGTLEEQQAKQLATRLLRNNIYKDNEYVYVADEDMTFVATPLDPQLHGTSFNDFKDGDGN
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCC
SVGQLIQRALGNRTGQIVEYTWTQKLPDGSIEEKLSIAEKTPHWGWVVGTGIGFNEVNAR
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHCHH
FWSTAQWQLILCLAIAGVILSSLIISIKRMLSLLGGEPKDVREAVQAVAKGKIQTSFETQ
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHH
AEQGSIYHAVQQMSQSLAELVSNLNSSMLALRGELQRVEDRAGSIAQLTETQQQSTEMIA
HHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TAMTEMASSANNVADSAGDTARNTDEADKQSQHTQLLIHNTVDNIQGLAGQLGTASEAVA
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHHCCCCHHHHHH
NLDNDVNNIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQS
HCCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCC
STKEIQLMINNLQEGSRNAIQTMNVCAATSESTVTESQNASEALQQIVIALESISSMSHQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IATAAAEQTQVSDDISKRINMIEESGNQLSDVVTESHNSTQTLASLSNELETWVNRFEVK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]