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The map label for this gene is pilC [H]

Identifier: 218710510

GI number: 218710510

Start: 2741665

End: 2742891

Strand: Direct

Name: pilC [H]

Synonym: VS_2549

Alternate gene names: 218710510

Gene position: 2741665-2742891 (Clockwise)

Preceding gene: 218710509

Following gene: 218710511

Centisome position: 83.1

GC content: 44.17

Gene sequence:

>1227_bases
ATGAGAACTAAACTGCAGTCACAATTAAAAAACTACCACTGGAAAGGCATAAATAGCTCAGGCAAAAAGGTGTCCGGTCA
AACCTTGGCTCTAGCCGAATTAGAAGTACGAGAAAAGCTCAAAGAGCAGCATATTCAGATTAAGAAAATCAAAAAGAAAA
GTATCTCAGCAGTCACTAGTTTAACACATCGAGTCAAAGCCAAAGACATCACCATTTTGACTCGACAACTTGCGACCATG
CTTGCCACTGGCGTGCCTATCGTTCAGGCCATTAAGCTAGTGTCAGACAATCACCGTAAAGCTGAAATGAAATCAATTTT
ATTGCACATTTGTCGAGGTGTCGAAGCGGGAACCCCAATATCAAAAGCGATGCGGACGGCAAGCACTCACTTTGACGACC
TGTACACCGATTTGGTCGCTACGGGCGAGCTTTCCGGAAACCTAGCGCAAGTCTTTGAACGCTTAGCAACCTATAGAGAA
AAGAGTGAGCAGCTAAAGTCTAAGGTCATAAAAGCACTGATTTACCCCACAATGGTGGTCGCTGTCGCGCTGACTGTCTC
TTACTTAATGCTCACCATGGTCATTCCTGAATTTGAATCGATGTTTTCAAGCTTCGGGGCAGACCTCCCTTGGTTTACTC
AACAAGTACTCTCCCTTTCACATTGGGTACAGGCTTACAGTCTTTATGCTGCCGTTGGCATAGGGTTAGTCACATTATTT
ACCTACCAACTGCGTCAACGGTCTTATTCCATTCGTTTATTATTCAGCCGTCTAGGTTTGCGATTCCCTATTCTTGGCGG
AGTATTGGCCAAAGCCTCAATCGCCAAATTCAGCCGAACCTTATCAACCAGTTTTAGTTCAGGGATTCCTATTTTAACCA
GCCTGAAGACCACAGCCAAAACCGCAGGTAACCTGCATTATGAATCGGCCATCATCGAGGTTCACCGTGAAACTGCCGCT
GGCATGCCGATGTATATCGCGATGCGCAATACCGATGCTTTTCCTGAGATGGTTTTACAGATGGTCATGATAGGAGAAGA
GTCTGGCAACCTTGATGACATGCTCAATAAAATCGCATCTATTTATGAATTTGAAGTCGACAACACCGTCGATAATTTAG
GTAAGATTTTAGAACCTCTTATCATCGTATTTTTAGGCACCGCTATTGGTGGACTGGTTGTCGCGATGTACTTACCGATC
TTTAATCTTATGAGTGTGTTAGGATAG

Upstream 100 bases:

>100_bases
GAGAACACTGCAAGAATCCGGTATCGATAAGTTGCTTGAAGGCACCACCAGCTATCAAGAACTGCAACGTGTTCTGTATC
TATAATCCATCGGAGCACTC

Downstream 100 bases:

>100_bases
CTAAAAGCAACCAACCCCCCCTCAAGCAGAGAACCACTGCTTGTATTGATTAAGTGGTAAAGGACACTATGGAAGTATTT
CACTACTATCCTTGGCTATT

Product: type IV pilin assembly protein pilC

Products: NA

Alternate protein names: Type IV-A pilus assembly protein pilC [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MRTKLQSQLKNYHWKGINSSGKKVSGQTLALAELEVREKLKEQHIQIKKIKKKSISAVTSLTHRVKAKDITILTRQLATM
LATGVPIVQAIKLVSDNHRKAEMKSILLHICRGVEAGTPISKAMRTASTHFDDLYTDLVATGELSGNLAQVFERLATYRE
KSEQLKSKVIKALIYPTMVVAVALTVSYLMLTMVIPEFESMFSSFGADLPWFTQQVLSLSHWVQAYSLYAAVGIGLVTLF
TYQLRQRSYSIRLLFSRLGLRFPILGGVLAKASIAKFSRTLSTSFSSGIPILTSLKTTAKTAGNLHYESAIIEVHRETAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGNLDDMLNKIASIYEFEVDNTVDNLGKILEPLIIVFLGTAIGGLVVAMYLPI
FNLMSVLG

Sequences:

>Translated_408_residues
MRTKLQSQLKNYHWKGINSSGKKVSGQTLALAELEVREKLKEQHIQIKKIKKKSISAVTSLTHRVKAKDITILTRQLATM
LATGVPIVQAIKLVSDNHRKAEMKSILLHICRGVEAGTPISKAMRTASTHFDDLYTDLVATGELSGNLAQVFERLATYRE
KSEQLKSKVIKALIYPTMVVAVALTVSYLMLTMVIPEFESMFSSFGADLPWFTQQVLSLSHWVQAYSLYAAVGIGLVTLF
TYQLRQRSYSIRLLFSRLGLRFPILGGVLAKASIAKFSRTLSTSFSSGIPILTSLKTTAKTAGNLHYESAIIEVHRETAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGNLDDMLNKIASIYEFEVDNTVDNLGKILEPLIIVFLGTAIGGLVVAMYLPI
FNLMSVLG
>Mature_408_residues
MRTKLQSQLKNYHWKGINSSGKKVSGQTLALAELEVREKLKEQHIQIKKIKKKSISAVTSLTHRVKAKDITILTRQLATM
LATGVPIVQAIKLVSDNHRKAEMKSILLHICRGVEAGTPISKAMRTASTHFDDLYTDLVATGELSGNLAQVFERLATYRE
KSEQLKSKVIKALIYPTMVVAVALTVSYLMLTMVIPEFESMFSSFGADLPWFTQQVLSLSHWVQAYSLYAAVGIGLVTLF
TYQLRQRSYSIRLLFSRLGLRFPILGGVLAKASIAKFSRTLSTSFSSGIPILTSLKTTAKTAGNLHYESAIIEVHRETAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGNLDDMLNKIASIYEFEVDNTVDNLGKILEPLIIVFLGTAIGGLVVAMYLPI
FNLMSVLG

Specific function: Involved in the translocation of the type IV pilin [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=400, Percent_Identity=29.5, Blast_Score=187, Evalue=8e-49,
Organism=Escherichia coli, GI1786295, Length=400, Percent_Identity=29, Blast_Score=171, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45174; Mature: 45174

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10024587; 10952301 [H]