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The map label for this gene is appC [H]

Identifier: 218710469

GI number: 218710469

Start: 2688741

End: 2689766

Strand: Direct

Name: appC [H]

Synonym: VS_2508

Alternate gene names: 218710469

Gene position: 2688741-2689766 (Clockwise)

Preceding gene: 218710468

Following gene: 218710470

Centisome position: 81.49

GC content: 47.27

Gene sequence:

>1026_bases
ATGAAAGATATTCTAAAACTCATTTGGCGTAACCCGATGGCCTTAACCGGCGTCATTATCCTAAGTATTTTTATTCTTGG
TGCTATTGCGGCTCCATTGATCACAAAACATGTGCCAGACAAACGTACAGGTAATCCACACGAATACCCTGGCTTCGTGG
TTAAGTCTGCACAAACTAACCCGGATGGCTGGGTTGCTCAAAACCTAGCAGACGATCGTCGTACGTTGATAATGTCTAAG
AAGGCAGACCACGTACTGGGCACAACTCGTATGGGTCGTGACGTTTGGTCACAAGTGGTATACGGCGCACGCGTATCTCT
TGCTGTAGGTTTTGGTGCGGGTCTTACCGTATGTTTACTAGCAACGGTTATCGGTGTTTCCGCTGGCTACTTTGGCGGCC
GTGTCGATGATGTTCTGACAGCCGCAATGAACATCATGCTGGTTATTCCTCAATATCCATTACTGTTCGTAGTTGCAGCC
TTTATCGGTGAGGCAGGGCCACTCACCATAACCTTGGTTATCGGCTTTATGTCCTGGGCTTGGGGCGCGCGTGTTGTTCG
TTCCCAGACCTTAGCACTGCGTGAAAAAGAGTTTGTAAAAGCCGCTGAAGTTCTGGGTGAATCTTCATTCCGTATTATCT
TCGTAGAGATTCTTCCAAACCTTATCTCTATCGTTGGCGCGAGCTTCATCGGTTCGGTGATGTACGCAATCATGATGGAA
GCAACGATTTCGTTCCTAGGTCTTGGTGACCCGAACACAATCAGCTGGGGCATCATGCTTTACAACGTTCAAACCTCTTC
ATCAATGCTGATTGGCGCTTGGTGGGAACTGTTGGCTCCTTGTATCGCATTGACACTACTTGTAACTGGTCTTGCTCTAC
TTAACTTCGCTGTCGATGAAATTGCCAACCCGCAACTGCGTTCTCACAAAGGCATGAAGCGTTGGAAGAAATTAGCAGCA
CAAGACAAAGAAGAACGTGAACCTGAACTACCACCACAAAATGCACTTTGGAGCGGAGATAAATAA

Upstream 100 bases:

>100_bases
AACTGCTTATCATGACGCTATTCATGCTGTTCTTTAACCTAGTTGCAGACATGCTTTACGTTGTTCTTGACCCTCGTCTT
CGTAAGGGTGGTAAATAATC

Downstream 100 bases:

>100_bases
TCATGTCTGAACCACTAATTTCTATCCGCAATTTATGCGTGGATTACATCACAGAGTCTGGCGATGTACGTGCGTGTAAC
AACGTAAGTTTCGACATTGC

Product: peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKDILKLIWRNPMALTGVIILSIFILGAIAAPLITKHVPDKRTGNPHEYPGFVVKSAQTNPDGWVAQNLADDRRTLIMSK
KADHVLGTTRMGRDVWSQVVYGARVSLAVGFGAGLTVCLLATVIGVSAGYFGGRVDDVLTAAMNIMLVIPQYPLLFVVAA
FIGEAGPLTITLVIGFMSWAWGARVVRSQTLALREKEFVKAAEVLGESSFRIIFVEILPNLISIVGASFIGSVMYAIMME
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDEIANPQLRSHKGMKRWKKLAA
QDKEEREPELPPQNALWSGDK

Sequences:

>Translated_341_residues
MKDILKLIWRNPMALTGVIILSIFILGAIAAPLITKHVPDKRTGNPHEYPGFVVKSAQTNPDGWVAQNLADDRRTLIMSK
KADHVLGTTRMGRDVWSQVVYGARVSLAVGFGAGLTVCLLATVIGVSAGYFGGRVDDVLTAAMNIMLVIPQYPLLFVVAA
FIGEAGPLTITLVIGFMSWAWGARVVRSQTLALREKEFVKAAEVLGESSFRIIFVEILPNLISIVGASFIGSVMYAIMME
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDEIANPQLRSHKGMKRWKKLAA
QDKEEREPELPPQNALWSGDK
>Mature_341_residues
MKDILKLIWRNPMALTGVIILSIFILGAIAAPLITKHVPDKRTGNPHEYPGFVVKSAQTNPDGWVAQNLADDRRTLIMSK
KADHVLGTTRMGRDVWSQVVYGARVSLAVGFGAGLTVCLLATVIGVSAGYFGGRVDDVLTAAMNIMLVIPQYPLLFVVAA
FIGEAGPLTITLVIGFMSWAWGARVVRSQTLALREKEFVKAAEVLGESSFRIIFVEILPNLISIVGASFIGSVMYAIMME
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDEIANPQLRSHKGMKRWKKLAA
QDKEEREPELPPQNALWSGDK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=307, Percent_Identity=27.6872964169381, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787054, Length=248, Percent_Identity=29.0322580645161, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=32.7868852459016, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789964, Length=257, Percent_Identity=32.6848249027237, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787498, Length=306, Percent_Identity=31.0457516339869, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788505, Length=176, Percent_Identity=33.5227272727273, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37137; Mature: 37137

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDILKLIWRNPMALTGVIILSIFILGAIAAPLITKHVPDKRTGNPHEYPGFVVKSAQTN
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCC
PDGWVAQNLADDRRTLIMSKKADHVLGTTRMGRDVWSQVVYGARVSLAVGFGAGLTVCLL
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHEEEECCCHHHHHHHH
ATVIGVSAGYFGGRVDDVLTAAMNIMLVIPQYPLLFVVAAFIGEAGPLTITLVIGFMSWA
HHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
WGARVVRSQTLALREKEFVKAAEVLGESSFRIIFVEILPNLISIVGASFIGSVMYAIMME
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDE
HHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANPQLRSHKGMKRWKKLAAQDKEEREPELPPQNALWSGDK
HCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKDILKLIWRNPMALTGVIILSIFILGAIAAPLITKHVPDKRTGNPHEYPGFVVKSAQTN
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCC
PDGWVAQNLADDRRTLIMSKKADHVLGTTRMGRDVWSQVVYGARVSLAVGFGAGLTVCLL
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHEEEECCCHHHHHHHH
ATVIGVSAGYFGGRVDDVLTAAMNIMLVIPQYPLLFVVAAFIGEAGPLTITLVIGFMSWA
HHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
WGARVVRSQTLALREKEFVKAAEVLGESSFRIIFVEILPNLISIVGASFIGSVMYAIMME
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDE
HHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANPQLRSHKGMKRWKKLAAQDKEEREPELPPQNALWSGDK
HCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]