Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 218710449

GI number: 218710449

Start: 2659324

End: 2660664

Strand: Reverse

Name: glmM

Synonym: VS_2488

Alternate gene names: 218710449

Gene position: 2660664-2659324 (Counterclockwise)

Preceding gene: 218710450

Following gene: 218710448

Centisome position: 80.64

GC content: 46.98

Gene sequence:

>1341_bases
ATGTCTGAAAAAAGACGTTACTTCGGCACAGATGGTGTACGTGGAAAAGTGGGCCAGTACCCAATCACACCTGATTTTGT
TTTGAAGCTTGGCTGGGCTGCTGGTCGTGTTCTTGCAAAGCAGGGCACAAAGAAAGTGATCATTGGTAAAGATACTCGTA
TTTCTGGCTACATGCTTGAGTCTGCTTTAGAAGCTGGCTTAGCTGCTGCTGGTCTTCAAGCTACGTTTACGGGGCCAATG
CCGACACCGGCTGTTGCCTACCTAACACAAACTTTCCGTGCTGAAGCGGGGATTGTTATCTCTGCATCGCACAACCCATA
TTACGATAACGGTATTAAGTTCTTCTCTTCTGAAGGGACTAAGTTGTCGGATGAAATTGAGTTGGCTATCGAAGCCGAAC
TAGACAAAGATATCGAGTGCGTGGAATCTTCCGAATTAGGTAAAGCGGTACGCCTAAATGATGCAGCAGGCCGTTATATT
GAATTTTGTAAAAGTACATTCCCACACAAAATGACGCTAGCGGGTATGAAAATTGTGGTGGATTGCGCGCATGGTGCGAC
TTACCACATTGCGCCGGCTGTATTTAAAGAGCTGGGTGCTGAGGTTGTTGCGATTGGTGTGGAGCCAAATGGCACTAACA
TCAACCATGAAGTCGGTGCGACTGATGTACGCGCTCTGCAAGCTAAAGTGGTTGAAGAAAAAGCGGCGTTAGGCCTTGGC
TTTGATGGTGATGGTGACCGCATCATCATGGTTGACGAGCTAGGCAATAAAGTTGATGGTGACCAAATCGCTTACATTAT
TGCTCGCGATGCACTGCGTCGTGGTGAGTTGAAAGGTGGCGTTGTTGGTACGCTAATGACCAACCTTGGGATGGAAAACG
GCCTTAAGCAGTTAGGTATTCCGTTTGTACGTGCTGCTGTCGGCGACCGTTACGTTATGGAACAACTTCTAGCTAAAGGC
TGGAAGATCGGTGCTGAGAACTCGGGGCACGTTATCCTATTAGATAAAGTGACGACAGGTGATGCTATCGTTGCTGCTCT
GCAAGTATTGGCCTCAGTTGTCGATAGTGAAATGACACTGAATGAACTTTCTCAAGGTATGACGTTATACCCTCAAGTTC
TAGAAAATGTTCGTTTCAGTGGTGATTCAAACCCACTAGAAGCAGAGGCTGTGAAAGCGGCTGTTATTGAAGTCGAGACG
GAACTCGGTGAGAAAGGTCGTGTGCTATTACGCAAATCGGGTACTGAGCCACTACTGCGCGTAATGGTCGAAGGTGAAGA
TGCTGAACTTGTTCAGAGTTCTGCACTGAAAATTGCTGATGCAGTAAAAGCGAATTGCTAA

Upstream 100 bases:

>100_bases
TCAAATTATTCGCGTTCACGATGTAGAAGATACATTGGAAGCGATGAAGATAATCGAAGTGATGAATAACAATCACTAAT
CATAATTAAGGAAAATCAAT

Downstream 100 bases:

>100_bases
TAAAACGTTTGCCGTAACAGGCGAAGTCGGTCTCACTTGTGGGGGCCGGGTTTTAGTTATGTGATGATTAAAAAGGGACG
CAAATGAGTTTTGTGTCCCT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSEKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTKKVIIGKDTRISGYMLESALEAGLAAAGLQATFTGPM
PTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTKLSDEIELAIEAELDKDIECVESSELGKAVRLNDAAGRYI
EFCKSTFPHKMTLAGMKIVVDCAHGATYHIAPAVFKELGAEVVAIGVEPNGTNINHEVGATDVRALQAKVVEEKAALGLG
FDGDGDRIIMVDELGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEQLLAKG
WKIGAENSGHVILLDKVTTGDAIVAALQVLASVVDSEMTLNELSQGMTLYPQVLENVRFSGDSNPLEAEAVKAAVIEVET
ELGEKGRVLLRKSGTEPLLRVMVEGEDAELVQSSALKIADAVKANC

Sequences:

>Translated_446_residues
MSEKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTKKVIIGKDTRISGYMLESALEAGLAAAGLQATFTGPM
PTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTKLSDEIELAIEAELDKDIECVESSELGKAVRLNDAAGRYI
EFCKSTFPHKMTLAGMKIVVDCAHGATYHIAPAVFKELGAEVVAIGVEPNGTNINHEVGATDVRALQAKVVEEKAALGLG
FDGDGDRIIMVDELGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEQLLAKG
WKIGAENSGHVILLDKVTTGDAIVAALQVLASVVDSEMTLNELSQGMTLYPQVLENVRFSGDSNPLEAEAVKAAVIEVET
ELGEKGRVLLRKSGTEPLLRVMVEGEDAELVQSSALKIADAVKANC
>Mature_445_residues
SEKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTKKVIIGKDTRISGYMLESALEAGLAAAGLQATFTGPMP
TPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTKLSDEIELAIEAELDKDIECVESSELGKAVRLNDAAGRYIE
FCKSTFPHKMTLAGMKIVVDCAHGATYHIAPAVFKELGAEVVAIGVEPNGTNINHEVGATDVRALQAKVVEEKAALGLGF
DGDGDRIIMVDELGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEQLLAKGW
KIGAENSGHVILLDKVTTGDAIVAALQVLASVVDSEMTLNELSQGMTLYPQVLENVRFSGDSNPLEAEAVKAAVIEVETE
LGEKGRVLLRKSGTEPLLRVMVEGEDAELVQSSALKIADAVKANC

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=442, Percent_Identity=72.8506787330317, Blast_Score=649, Evalue=0.0,
Organism=Escherichia coli, GI1788361, Length=458, Percent_Identity=25.5458515283843, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_VIBSL (B7VJI1)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418070.1
- ProteinModelPortal:   B7VJI1
- GeneID:   7162023
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2488
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK10887
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47600; Mature: 47469

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 103-103

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTKKVIIGKDTRISGYMLE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCHHHHHH
SALEAGLAAAGLQATFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGT
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCC
KLSDEIELAIEAELDKDIECVESSELGKAVRLNDAAGRYIEFCKSTFPHKMTLAGMKIVV
CCCCCEEEEEEECCCCCHHHHCHHHCCCEEEECCHHHHHHHHHHHCCCCEEEECCEEEEE
DCAHGATYHIAPAVFKELGAEVVAIGVEPNGTNINHEVGATDVRALQAKVVEEKAALGLG
EECCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECC
FDGDGDRIIMVDELGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGI
CCCCCCEEEEEECCCCCCCCCCEEEHEEHHHHHHCCCCCCHHHHHHHHCCHHCCHHHHCC
PFVRAAVGDRYVMEQLLAKGWKIGAENSGHVILLDKVTTGDAIVAALQVLASVVDSEMTL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCH
NELSQGMTLYPQVLENVRFSGDSNPLEAEAVKAAVIEVETELGEKGRVLLRKSGTEPLLR
HHHHCCCEEHHHHHHCCCCCCCCCCCHHHHHHHHEEEEEHHCCCCCCEEEEECCCCCEEE
VMVEGEDAELVQSSALKIADAVKANC
EEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTKKVIIGKDTRISGYMLE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCHHHHHH
SALEAGLAAAGLQATFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGT
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCC
KLSDEIELAIEAELDKDIECVESSELGKAVRLNDAAGRYIEFCKSTFPHKMTLAGMKIVV
CCCCCEEEEEEECCCCCHHHHCHHHCCCEEEECCHHHHHHHHHHHCCCCEEEECCEEEEE
DCAHGATYHIAPAVFKELGAEVVAIGVEPNGTNINHEVGATDVRALQAKVVEEKAALGLG
EECCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECC
FDGDGDRIIMVDELGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGI
CCCCCCEEEEEECCCCCCCCCCEEEHEEHHHHHHCCCCCCHHHHHHHHCCHHCCHHHHCC
PFVRAAVGDRYVMEQLLAKGWKIGAENSGHVILLDKVTTGDAIVAALQVLASVVDSEMTL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCH
NELSQGMTLYPQVLENVRFSGDSNPLEAEAVKAAVIEVETELGEKGRVLLRKSGTEPLLR
HHHHCCCEEHHHHHHCCCCCCCCCCCHHHHHHHHEEEEEHHCCCCCCEEEEECCCCCEEE
VMVEGEDAELVQSSALKIADAVKANC
EEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA