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The map label for this gene is xni

Identifier: 218710358

GI number: 218710358

Start: 2563332

End: 2564105

Strand: Direct

Name: xni

Synonym: VS_2394

Alternate gene names: 218710358

Gene position: 2563332-2564105 (Clockwise)

Preceding gene: 218710357

Following gene: 218710367

Centisome position: 77.69

GC content: 45.74

Gene sequence:

>774_bases
ATGTCTATCCATCTTGTTATTATCGATGCCTTGAACCTCATCCGACGCGTGCACTCTGTTCAGTCGGACCCAACCGATAT
TGCAAGAACCATCACCACGACTGCTCGTACTCTTAATCGCATCCTAAACGAATCAAAACCCACTCATATCATTGCGGTAT
TTGATCATCATTTACAAGATCGAGGTTGGCGCGCGGAAGTCCTTCCCGCTTATAAGCAAAACCGTAAGCCGATGCCAGAA
CCATTGATGAAAGGTCTCGATGCGATTCAACAAGCTTGGTGGGAATTAGGGATTGATTCACTGCTCTCTGACGGCGATGA
AGCGGATGATCTAGTTGCAACATTGGCAAAGAAAGTCGCTGACCACGGAGAAACTGTCACTATCATTTCGACAGATAAGG
GCTACTGCCAACTGTTGTCTCCAACGCTACAAATCCGTGATTATTTCCAACACCGTTGGTTAGATAAGCCCTTTATCGAA
GCGGAATTTGGCGTAAAGCCAGAGCAACTGGCAGATTACTGGGGATTAACGGGCGTCAGCTCAAGCCAAGTCCCCGGAAT
TCCAGGTATAGGGCCAAAAGCAGCCAAAGAGATATTAACGACATACCCTGATATCGAAACAGCATTCCTAGCTGAAGACT
TACCGAAAAAGTATCGTAAGAAATTCGATGAGCATATCGAGTCGGCTCGCGTATGTAAGCTCGTTTCTGCACTCAAAACA
GACATCGATTTAGGTTTTAATCTGCAAGATATTCGCTACGAAGCTGTGTCTTAA

Upstream 100 bases:

>100_bases
AAGTCATGACGTTTACGTCACCAAAGTTTCAACTCACCAAGTGATACGTTACTATAAGGGGCTAGCAGCCCCTTATTTAT
TGCCTATTTAGTGGAAACTT

Downstream 100 bases:

>100_bases
TCTGACGTCACAAATTCAGTCATTAAAGCTAACCGTTAGAAATAAATCCGCTTATAAATCAACAAATAGAAAATAAATCA
TTAGAAAGCAGAAAGCCTTA

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSIHLVIIDALNLIRRVHSVQSDPTDIARTITTTARTLNRILNESKPTHIIAVFDHHLQDRGWRAEVLPAYKQNRKPMPE
PLMKGLDAIQQAWWELGIDSLLSDGDEADDLVATLAKKVADHGETVTIISTDKGYCQLLSPTLQIRDYFQHRWLDKPFIE
AEFGVKPEQLADYWGLTGVSSSQVPGIPGIGPKAAKEILTTYPDIETAFLAEDLPKKYRKKFDEHIESARVCKLVSALKT
DIDLGFNLQDIRYEAVS

Sequences:

>Translated_257_residues
MSIHLVIIDALNLIRRVHSVQSDPTDIARTITTTARTLNRILNESKPTHIIAVFDHHLQDRGWRAEVLPAYKQNRKPMPE
PLMKGLDAIQQAWWELGIDSLLSDGDEADDLVATLAKKVADHGETVTIISTDKGYCQLLSPTLQIRDYFQHRWLDKPFIE
AEFGVKPEQLADYWGLTGVSSSQVPGIPGIGPKAAKEILTTYPDIETAFLAEDLPKKYRKKFDEHIESARVCKLVSALKT
DIDLGFNLQDIRYEAVS
>Mature_256_residues
SIHLVIIDALNLIRRVHSVQSDPTDIARTITTTARTLNRILNESKPTHIIAVFDHHLQDRGWRAEVLPAYKQNRKPMPEP
LMKGLDAIQQAWWELGIDSLLSDGDEADDLVATLAKKVADHGETVTIISTDKGYCQLLSPTLQIRDYFQHRWLDKPFIEA
EFGVKPEQLADYWGLTGVSSSQVPGIPGIGPKAAKEILTTYPDIETAFLAEDLPKKYRKKFDEHIESARVCKLVSALKTD
IDLGFNLQDIRYEAVS

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain

Homologues:

Organism=Escherichia coli, GI226510970, Length=253, Percent_Identity=50.197628458498, Blast_Score=265, Evalue=2e-72,
Organism=Escherichia coli, GI1790294, Length=265, Percent_Identity=26.0377358490566, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XNI_VIBSL (B7VJ90)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002417979.1
- GeneID:   7161932
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2394
- HOGENOM:   HBG701384
- OMA:   GIDAIQD
- ProtClustDB:   PRK09482
- HAMAP:   MF_01192
- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR022895
- SMART:   SM00279

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; SSF47807 5_3_exo_C

EC number: 3.1.11.- [C]

Molecular weight: Translated: 28941; Mature: 28810

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHLVIIDALNLIRRVHSVQSDPTDIARTITTTARTLNRILNESKPTHIIAVFDHHLQD
CEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHC
RGWRAEVLPAYKQNRKPMPEPLMKGLDAIQQAWWELGIDSLLSDGDEADDLVATLAKKVA
CCCCHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHH
DHGETVTIISTDKGYCQLLSPTLQIRDYFQHRWLDKPFIEAEFGVKPEQLADYWGLTGVS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCC
SSQVPGIPGIGPKAAKEILTTYPDIETAFLAEDLPKKYRKKFDEHIESARVCKLVSALKT
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIDLGFNLQDIRYEAVS
HHCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SIHLVIIDALNLIRRVHSVQSDPTDIARTITTTARTLNRILNESKPTHIIAVFDHHLQD
EEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHC
RGWRAEVLPAYKQNRKPMPEPLMKGLDAIQQAWWELGIDSLLSDGDEADDLVATLAKKVA
CCCCHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHH
DHGETVTIISTDKGYCQLLSPTLQIRDYFQHRWLDKPFIEAEFGVKPEQLADYWGLTGVS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCC
SSQVPGIPGIGPKAAKEILTTYPDIETAFLAEDLPKKYRKKFDEHIESARVCKLVSALKT
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIDLGFNLQDIRYEAVS
HHCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA