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The map label for this gene is qmcA [H]

Identifier: 218710248

GI number: 218710248

Start: 2450879

End: 2451808

Strand: Direct

Name: qmcA [H]

Synonym: VS_2281

Alternate gene names: 218710248

Gene position: 2450879-2451808 (Clockwise)

Preceding gene: 218710247

Following gene: 218710249

Centisome position: 74.28

GC content: 45.81

Gene sequence:

>930_bases
ATGGCTATTGATACATTGATTACTATCGGCGTCTTTACTGCCGTCGCAATATTGTTTATTTTCGCCGGAGTAAAAACGGT
TCCGCAAGGCAATAACTGGACCGTAGAACGCTTCGGCCGTTATACACAAACCCTCCAACCAGGTCTGAACCTGATCATTC
CATTTATCGATAAAATCGGACAACGCATCAGTATGATGGAACGTGTTCTCGACATCCCGGCACAAGAAGTCATCTCCAAA
GATAATGCAAATGTGGTTATTGATGCGGTGTGTTTCGTTCAAGTGATCGACGCGCCTAAAGCGGCTTATGAGGTGAATGA
TCTTGAGCACGCGATTCGTAATTTAACTCTCACCAATATCCGTACTGTACTGGGCTCGATGGAACTGGATGAAATGCTCA
GCCAGCGAGACATGATTAACACCAAATTATTGAATATCGTTGATGAAGCGACAAACCCTTGGGGTGTCAAAGTTACACGT
ATCGAAATCAAAGACGTACAGCCACCAGCAGACCTTACCGCTGCGATGAATGCTCAGATGAAAGCCGAGCGTAACAAACG
TGCAGATATCCTAGAGGCAGAGGGTGTACGACAAGCTGAGATATTGAAAGCAGAAGGTCACAAGCAATCAGAAATCTTAA
AAGCAGAAGGCCAAAAGCAAGCCGCGATACTTCAAGCTGAAGCTCGTGAACGGGCTGCCGAAGCTGAGGCTAAAGCGACA
GAAATGGTATCAACAGCGATTGCTCAAGGTGACATGCAAGCAGTCAATTACTTTATTGCACAAGGTTACACCGACGCACT
GAAGTCTATTGGCCAAGCAGAAAACGGTAAGATCATCATGCTACCGCTCGAAGCGACTGGACTAATGGGTTCTGTTGCGG
GTATTGCAGAGATGTTTGCACATAAGAATGACAAGGGTAGTAAGGACTAA

Upstream 100 bases:

>100_bases
TTTTATGGCCCATTTCTCATTTATAAATTTGCTCAGAATTTAAATATGAGCCAGTATCAATACTGAACTATCAAAAACTT
AAACTTGCAAAGGATTTTGT

Downstream 100 bases:

>100_bases
CTTATGGTCGAATTGCTCGAACAAGTAAACTACTGGCATTGGTTAGCGTTTGGCCTAGCATTGTTAGCGCTTGAGCTAAT
TGGAACCGCTGGTTACTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAIDTLITIGVFTAVAILFIFAGVKTVPQGNNWTVERFGRYTQTLQPGLNLIIPFIDKIGQRISMMERVLDIPAQEVISK
DNANVVIDAVCFVQVIDAPKAAYEVNDLEHAIRNLTLTNIRTVLGSMELDEMLSQRDMINTKLLNIVDEATNPWGVKVTR
IEIKDVQPPADLTAAMNAQMKAERNKRADILEAEGVRQAEILKAEGHKQSEILKAEGQKQAAILQAEARERAAEAEAKAT
EMVSTAIAQGDMQAVNYFIAQGYTDALKSIGQAENGKIIMLPLEATGLMGSVAGIAEMFAHKNDKGSKD

Sequences:

>Translated_309_residues
MAIDTLITIGVFTAVAILFIFAGVKTVPQGNNWTVERFGRYTQTLQPGLNLIIPFIDKIGQRISMMERVLDIPAQEVISK
DNANVVIDAVCFVQVIDAPKAAYEVNDLEHAIRNLTLTNIRTVLGSMELDEMLSQRDMINTKLLNIVDEATNPWGVKVTR
IEIKDVQPPADLTAAMNAQMKAERNKRADILEAEGVRQAEILKAEGHKQSEILKAEGQKQAAILQAEARERAAEAEAKAT
EMVSTAIAQGDMQAVNYFIAQGYTDALKSIGQAENGKIIMLPLEATGLMGSVAGIAEMFAHKNDKGSKD
>Mature_308_residues
AIDTLITIGVFTAVAILFIFAGVKTVPQGNNWTVERFGRYTQTLQPGLNLIIPFIDKIGQRISMMERVLDIPAQEVISKD
NANVVIDAVCFVQVIDAPKAAYEVNDLEHAIRNLTLTNIRTVLGSMELDEMLSQRDMINTKLLNIVDEATNPWGVKVTRI
EIKDVQPPADLTAAMNAQMKAERNKRADILEAEGVRQAEILKAEGHKQSEILKAEGQKQAAILQAEARERAAEAEAKATE
MVSTAIAQGDMQAVNYFIAQGYTDALKSIGQAENGKIIMLPLEATGLMGSVAGIAEMFAHKNDKGSKD

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=262, Percent_Identity=37.0229007633588, Blast_Score=175, Evalue=4e-44,
Organism=Homo sapiens, GI38016911, Length=188, Percent_Identity=34.5744680851064, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI221316744, Length=189, Percent_Identity=33.8624338624339, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI21686995, Length=189, Percent_Identity=33.8624338624339, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI7657615, Length=174, Percent_Identity=28.1609195402299, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI20149563, Length=178, Percent_Identity=29.2134831460674, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1786697, Length=303, Percent_Identity=72.2772277227723, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1790616, Length=211, Percent_Identity=25.5924170616114, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32564147, Length=285, Percent_Identity=35.7894736842105, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17569493, Length=177, Percent_Identity=35.5932203389831, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI193209764, Length=177, Percent_Identity=35.5932203389831, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17569497, Length=178, Percent_Identity=32.5842696629214, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71989948, Length=159, Percent_Identity=37.1069182389937, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17569499, Length=194, Percent_Identity=36.5979381443299, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71989955, Length=159, Percent_Identity=37.1069182389937, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17570459, Length=189, Percent_Identity=35.4497354497354, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71987612, Length=199, Percent_Identity=34.1708542713568, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI25153583, Length=199, Percent_Identity=34.1708542713568, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71987621, Length=199, Percent_Identity=34.1708542713568, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32566490, Length=201, Percent_Identity=32.3383084577114, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193210507, Length=153, Percent_Identity=38.562091503268, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17570161, Length=153, Percent_Identity=38.562091503268, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71989963, Length=122, Percent_Identity=34.4262295081967, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550506, Length=283, Percent_Identity=37.8091872791519, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI62484448, Length=197, Percent_Identity=36.0406091370558, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281365664, Length=198, Percent_Identity=35.8585858585859, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24657857, Length=197, Percent_Identity=36.0406091370558, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI62484274, Length=197, Percent_Identity=36.0406091370558, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI45556022, Length=193, Percent_Identity=34.7150259067358, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI18860517, Length=196, Percent_Identity=32.6530612244898, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281361631, Length=194, Percent_Identity=28.3505154639175, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573263, Length=199, Percent_Identity=26.6331658291457, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281361633, Length=231, Percent_Identity=27.7056277056277, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356845, Length=200, Percent_Identity=27.5, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281361635, Length=131, Percent_Identity=26.7175572519084, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33748; Mature: 33617

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01270 BAND_7

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDTLITIGVFTAVAILFIFAGVKTVPQGNNWTVERFGRYTQTLQPGLNLIIPFIDKIG
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
QRISMMERVLDIPAQEVISKDNANVVIDAVCFVQVIDAPKAAYEVNDLEHAIRNLTLTNI
HHHHHHHHHHCCCHHHHHCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RTVLGSMELDEMLSQRDMINTKLLNIVDEATNPWGVKVTRIEIKDVQPPADLTAAMNAQM
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHH
KAERNKRADILEAEGVRQAEILKAEGHKQSEILKAEGQKQAAILQAEARERAAEAEAKAT
HHHHCCCCCCHHHCCCCHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
EMVSTAIAQGDMQAVNYFIAQGYTDALKSIGQAENGKIIMLPLEATGLMGSVAGIAEMFA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
HKNDKGSKD
CCCCCCCCC
>Mature Secondary Structure 
AIDTLITIGVFTAVAILFIFAGVKTVPQGNNWTVERFGRYTQTLQPGLNLIIPFIDKIG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
QRISMMERVLDIPAQEVISKDNANVVIDAVCFVQVIDAPKAAYEVNDLEHAIRNLTLTNI
HHHHHHHHHHCCCHHHHHCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RTVLGSMELDEMLSQRDMINTKLLNIVDEATNPWGVKVTRIEIKDVQPPADLTAAMNAQM
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHH
KAERNKRADILEAEGVRQAEILKAEGHKQSEILKAEGQKQAAILQAEARERAAEAEAKAT
HHHHCCCCCCHHHCCCCHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
EMVSTAIAQGDMQAVNYFIAQGYTDALKSIGQAENGKIIMLPLEATGLMGSVAGIAEMFA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
HKNDKGSKD
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]