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The map label for this gene is htpG

Identifier: 218710236

GI number: 218710236

Start: 2440375

End: 2442279

Strand: Reverse

Name: htpG

Synonym: VS_2269

Alternate gene names: 218710236

Gene position: 2442279-2440375 (Counterclockwise)

Preceding gene: 218710240

Following gene: 218710235

Centisome position: 74.02

GC content: 44.67

Gene sequence:

>1905_bases
ATGAGCGAAACGGCAACGCAAAATAAAGAGACTCGTGGCTTTCAATCTGAAGTAAAACAACTACTTCACCTAATGATTCA
CTCACTGTATTCAAATAAAGAAATCTTCCTACGTGAGCTGATCTCTAACGCATCTGACGCGGCTGATAAGCTTCGTTTTC
AAGCGCTATCAAATGGCGACCTTTACCAAGGCGATGCTGATTTAGGTGTGAAACTTTCGTTCAACGCTGAAGCAAATACT
TTAACGATCTCTGATAACGGCATAGGTATGAGCCGCGACAACGTTATTGAGCATTTAGGTACTATTGCTAAGTCAGGCAC
AGCTGACTTTTTCTCAAAGCTGTCTGAAGACCAAAGCAAAGACTCTCAGCTTATTGGCCAATTTGGTGTTGGTTTCTATT
CTGCATTTATCGTTGCAGACGCAGTGACTGTTCGCACTCGAGCAGCTGGACTTGCTAATGACCAAGCCGTGCAATGGCAC
TCTGCGGGTGAAGGTGATTACACTATCGAAGACATCACGAAAGAATCTCGTGGTACAGACATCATTCTTCATATGCGTGA
AGACGGCAAAGAGTTCTTAAATGAATGGCGTCTGCGTGAAGTGATTGGTAAGTATTCTGATCACATCGGTATCCCTGTCT
CCATCTTCACAGCGGTGAAAGATGACGAAGGTAAAGACACCGAAGAGAAGCATTGGGAGCAGATTAACAAGGCTCAAGCG
CTTTGGACTCGTAACAAGTCTGATATCGAGAAAGAAGAGTACCAAGAGTTTTACAAGCACGTATCTCACGACTTTGCTGA
TCCACTAACGTGGAGCCATAACAAAGTTGAAGGTAAGAACGACTACACAAGCCTACTTTACATCCCAGCTAAAGCACCTT
GGGATATGATGAATCGTGACCATAAGAGCGGCCTTAAGCTTTATGTACAGCGCGTATTCATCATGGATGATGCAGAGCAG
TTCATGCCATCTTACATGCGTTTCGTTCGCGGCTTGATTGATTCAAACGATTTACCACTGAACGTGTCTCGTGAAATCCT
GCAAGATAATAAGGTGACTCAGTCTCTTCGTGGCGCATGTACCAAGCGTGTACTCACTATGCTTGAGCGCATGGCGAAGA
ATGACAACGACAAGTACTTGGAGTTTTGGAAAGAGTTCGGCCTAGTACTGAAAGAAGGCCCTGCTGAAGACATGGCGAAC
AAAGAAAAAATCGCAGGTCTACTTCGTTTCTCATCAACAGAAGTGGATTCTTCTGAACAAACTATCGGCCTAGCATCTTA
CGTTGAGCGCATGAAAGAAGGCCAAGACAAGATCTATTACCTAACAGCAGATAGTTACGCTGCCGCTAAGAACAGCCCAC
ACTTAGAGCAGTTCAAAGCAAAAGGTATCGAAGTTGTTCTCATGTACGATCGTATCGATGAGTACGTAATGAATTACCTG
ACTGACTTCGACGGTAAACAGTTCCAATCGATCACTAAAGCAGGCTTAGACCTAAGCAAGTTTGAAGGTGAAGAAGAGAA
AGAGAAGCAAAAAGAGACAGAAGAAGAGTTCAAATCTGTTGTTGAGCGCACTCAATCTTACCTAGGTGGTCGTGTTAAAG
AAGTTCGTACTACTTTCAAGCTCGCAACAACACCTGCCGTTGTGGTGACTGATGACTTCGAAATGGGCACGCAAATGGCT
AAGCTTCTTGAAGCTGCGGGTCAAGCGGCACCTGAAGTGAAGTACATCTTTGAGATTAACCCTGAGCACGCACTTGTGAA
ACAGATGGCTGATGAAGCGGACGAACAAGCGTTTGGTCGTTGGGTTGAGCTACTACTTGGTCAAGCTATGCTGGCTGAAA
AGGGCTCAATGGAAGATCCGTCACAATTCTTAGGTGCAATCAACGAACTACTGACAAAACGTTAG

Upstream 100 bases:

>100_bases
ATTTACATTTGTCATCCTCATGTTAATGAACAGAAGAGAGGCATAATGTGCAATGCCCCTATGATTATTCAACATAAAGT
ATAGATGTTTTGGAGTAAAA

Downstream 100 bases:

>100_bases
TCTTTCGACTTTGGGCTAAGCTCATAATTATAATTAAAAGCTCGCTAATGCGGGCTTTTTTTATGAACGTCGCTTAACTT
CATCGAAATGTCGCTAAAGT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MSETATQNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNGDLYQGDADLGVKLSFNAEANT
LTISDNGIGMSRDNVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLANDQAVQWH
SAGEGDYTIEDITKESRGTDIILHMREDGKEFLNEWRLREVIGKYSDHIGIPVSIFTAVKDDEGKDTEEKHWEQINKAQA
LWTRNKSDIEKEEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPWDMMNRDHKSGLKLYVQRVFIMDDAEQ
FMPSYMRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERMAKNDNDKYLEFWKEFGLVLKEGPAEDMAN
KEKIAGLLRFSSTEVDSSEQTIGLASYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEYVMNYL
TDFDGKQFQSITKAGLDLSKFEGEEEKEKQKETEEEFKSVVERTQSYLGGRVKEVRTTFKLATTPAVVVTDDFEMGTQMA
KLLEAAGQAAPEVKYIFEINPEHALVKQMADEADEQAFGRWVELLLGQAMLAEKGSMEDPSQFLGAINELLTKR

Sequences:

>Translated_634_residues
MSETATQNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNGDLYQGDADLGVKLSFNAEANT
LTISDNGIGMSRDNVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLANDQAVQWH
SAGEGDYTIEDITKESRGTDIILHMREDGKEFLNEWRLREVIGKYSDHIGIPVSIFTAVKDDEGKDTEEKHWEQINKAQA
LWTRNKSDIEKEEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPWDMMNRDHKSGLKLYVQRVFIMDDAEQ
FMPSYMRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERMAKNDNDKYLEFWKEFGLVLKEGPAEDMAN
KEKIAGLLRFSSTEVDSSEQTIGLASYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEYVMNYL
TDFDGKQFQSITKAGLDLSKFEGEEEKEKQKETEEEFKSVVERTQSYLGGRVKEVRTTFKLATTPAVVVTDDFEMGTQMA
KLLEAAGQAAPEVKYIFEINPEHALVKQMADEADEQAFGRWVELLLGQAMLAEKGSMEDPSQFLGAINELLTKR
>Mature_633_residues
SETATQNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNGDLYQGDADLGVKLSFNAEANTL
TISDNGIGMSRDNVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLANDQAVQWHS
AGEGDYTIEDITKESRGTDIILHMREDGKEFLNEWRLREVIGKYSDHIGIPVSIFTAVKDDEGKDTEEKHWEQINKAQAL
WTRNKSDIEKEEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPWDMMNRDHKSGLKLYVQRVFIMDDAEQF
MPSYMRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERMAKNDNDKYLEFWKEFGLVLKEGPAEDMANK
EKIAGLLRFSSTEVDSSEQTIGLASYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEYVMNYLT
DFDGKQFQSITKAGLDLSKFEGEEEKEKQKETEEEFKSVVERTQSYLGGRVKEVRTTFKLATTPAVVVTDDFEMGTQMAK
LLEAAGQAAPEVKYIFEINPEHALVKQMADEADEQAFGRWVELLLGQAMLAEKGSMEDPSQFLGAINELLTKR

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=670, Percent_Identity=36.5671641791045, Blast_Score=408, Evalue=1e-114,
Organism=Homo sapiens, GI4507677, Length=645, Percent_Identity=35.968992248062, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI155722983, Length=634, Percent_Identity=36.1198738170347, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=35.8536585365854, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=35.8536585365854, Blast_Score=251, Evalue=1e-66,
Organism=Escherichia coli, GI1786679, Length=627, Percent_Identity=68.4210526315789, Blast_Score=889, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=672, Percent_Identity=36.6071428571429, Blast_Score=439, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17542208, Length=685, Percent_Identity=35.6204379562044, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115535205, Length=639, Percent_Identity=33.9593114241002, Blast_Score=335, Evalue=5e-92,
Organism=Caenorhabditis elegans, GI115535167, Length=427, Percent_Identity=36.5339578454333, Blast_Score=270, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6323840, Length=683, Percent_Identity=36.0175695461201, Blast_Score=425, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6325016, Length=209, Percent_Identity=44.0191387559809, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI17647529, Length=671, Percent_Identity=37.5558867362146, Blast_Score=447, Evalue=1e-125,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=36.2701908957416, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24586016, Length=666, Percent_Identity=33.033033033033, Blast_Score=363, Evalue=1e-100,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_VIBSL (B7VII6)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002417857.1
- GeneID:   7161811
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2269
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71916; Mature: 71784

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETATQNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCC
LYQGDADLGVKLSFNAEANTLTISDNGIGMSRDNVIEHLGTIAKSGTADFFSKLSEDQSK
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCH
DSQLIGQFGVGFYSAFIVADAVTVRTRAAGLANDQAVQWHSAGEGDYTIEDITKESRGTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEHHHHHHCCCCCE
IILHMREDGKEFLNEWRLREVIGKYSDHIGIPVSIFTAVKDDEGKDTEEKHWEQINKAQA
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
LWTRNKSDIEKEEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPWDMMNRD
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCC
HKSGLKLYVQRVFIMDDAEQFMPSYMRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGAC
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TKRVLTMLERMAKNDNDKYLEFWKEFGLVLKEGPAEDMANKEKIAGLLRFSSTEVDSSEQ
HHHHHHHHHHHHCCCCHHHHHHHHHHCHHCCCCCCHHHCCHHHHHHHHHHCCCCCCCCHH
TIGLASYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEYVMNYL
HHHHHHHHHHHHCCCCEEEEEECCCHHCCCCCCCHHHHHHCCEEEEEEHHHHHHHHHHHH
TDFDGKQFQSITKAGLDLSKFEGEEEKEKQKETEEEFKSVVERTQSYLGGRVKEVRTTFK
HCCCCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LATTPAVVVTDDFEMGTQMAKLLEAAGQAAPEVKYIFEINPEHALVKQMADEADEQAFGR
EECCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
WVELLLGQAMLAEKGSMEDPSQFLGAINELLTKR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SETATQNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNGD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCC
LYQGDADLGVKLSFNAEANTLTISDNGIGMSRDNVIEHLGTIAKSGTADFFSKLSEDQSK
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCH
DSQLIGQFGVGFYSAFIVADAVTVRTRAAGLANDQAVQWHSAGEGDYTIEDITKESRGTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEHHHHHHCCCCCE
IILHMREDGKEFLNEWRLREVIGKYSDHIGIPVSIFTAVKDDEGKDTEEKHWEQINKAQA
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
LWTRNKSDIEKEEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPWDMMNRD
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCC
HKSGLKLYVQRVFIMDDAEQFMPSYMRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGAC
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TKRVLTMLERMAKNDNDKYLEFWKEFGLVLKEGPAEDMANKEKIAGLLRFSSTEVDSSEQ
HHHHHHHHHHHHCCCCHHHHHHHHHHCHHCCCCCCHHHCCHHHHHHHHHHCCCCCCCCHH
TIGLASYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEYVMNYL
HHHHHHHHHHHHCCCCEEEEEECCCHHCCCCCCCHHHHHHCCEEEEEEHHHHHHHHHHHH
TDFDGKQFQSITKAGLDLSKFEGEEEKEKQKETEEEFKSVVERTQSYLGGRVKEVRTTFK
HCCCCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LATTPAVVVTDDFEMGTQMAKLLEAAGQAAPEVKYIFEINPEHALVKQMADEADEQAFGR
EECCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
WVELLLGQAMLAEKGSMEDPSQFLGAINELLTKR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA