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The map label for this gene is sucC [H]

Identifier: 218710209

GI number: 218710209

Start: 2407572

End: 2408738

Strand: Reverse

Name: sucC [H]

Synonym: VS_2241

Alternate gene names: 218710209

Gene position: 2408738-2407572 (Counterclockwise)

Preceding gene: 218710210

Following gene: 218710208

Centisome position: 73.01

GC content: 46.53

Gene sequence:

>1167_bases
ATGAATTTGCATGAATACCAAGCCAAACAGCTGTTTGCAGAATTCGGTTTGCCTGTACCAGAAGGTTTCGCATGTGATAC
TGCACAAGAAGCTTTCGAAGCTGCAGGTCGTATCAGTACAGCCAAGAAAGTCGTTAAGTGTCAAGTACACGCTGGTGGTC
GCGGTAAAGCGGGCGGCGTAGAGCTACATGACACCAAAGAAGGCGTTAAAGAGTTTGCACAAAAGTGGCTAGGTAAAAAC
CTAGTGACTTACCAAACAGACGCTAATGGTCAACCTGTAACAAAGATCCTAGTTGAAGAAGCATCGAACATTGCTAACGA
ACTTTACCTAGGTGCTGTTGTTGACCGTGCAACGCGCAAAATTGTATTCATGGCGTCAACTGAAGGCGGTGTGGACATTG
AGAAAATCGCTGAAGAAACTCCAGAGTTGATTCACCAATCAGCGATCGATCCTCTAGTGGGCCCTCAAGCTTACCAAGGC
CGTGAACTTGCGTTCAAACTTGGTCTAGTTGGCGATCAAATCAAACAGTTCGTTAAGATCTTCATGGGTCTTGGCCAAAT
GTTCTCTCAGTACGACCTAGCTCTACTAGAAATCAACCCGCTTGTAATTACTGGCGAAGGCAACCTGCTTTGTCTAGACG
GCAAGATCAACATTGACTCAAACGCAATGTACCGTCAGCCAAAGCTTCGTGAAATGCACGATCCTTCACAAGAAGACGAG
CGTGAAGCGCACGCAGCTCAGTGGGAACTGAACTACGTAGCACTTGATGGCAACGTTGGCTGTATGGTTAACGGTGCAGG
CCTTGCGATGGGTACGATGGATATCGTAAACCTACACGGCGGCAAGCCAGCAAACTTCCTTGATGTAGGCGGCGGCGCGA
CAAAAGAGCGTGTAGCTGAAGCATTCAAGATCATCCTTTCTGATGACAATGTTAAAGCAGTACTCGTAAACATTTTCGGT
GGCATCGTTCGTTGTGACATGATCGCTGAAGGTATTATTGGTGCAGTTAAAGAAGTTGGCGTAACAGTTCCTGTAGTTGT
TCGTCTAGAAGGTACAAACGCAGACCTAGGTCGTGAAGTACTTGCTAATTCTGATGTTGATATCATTGCTGCTGTATCTC
TAACAGATGCTGCTCAGAAAGTTGTTGCTGCTGCGGAGGCTAAATAA

Upstream 100 bases:

>100_bases
GGACAGCAGTTGATTTGAGAAGACCCTACAGACGTACCACAGGAAACTGTGTCGTTATGGAAATAATAATCCCTTAAGGG
AAAATAAACGGAATATCAAA

Downstream 100 bases:

>100_bases
TGTCTGTATTAATTAACAAAGACACTAAAGTAATCTGTCAGGGTTTCACTGGCGGTCAAGGTACATTCCACTCAGACCAA
GCTATCGCATACGGTACGCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKQLFAEFGLPVPEGFACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRKIVFMASTEGGVDIEKIAEETPELIHQSAIDPLVGPQAYQG
RELAFKLGLVGDQIKQFVKIFMGLGQMFSQYDLALLEINPLVITGEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVTVPVVVRLEGTNADLGREVLANSDVDIIAAVSLTDAAQKVVAAAEAK

Sequences:

>Translated_388_residues
MNLHEYQAKQLFAEFGLPVPEGFACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRKIVFMASTEGGVDIEKIAEETPELIHQSAIDPLVGPQAYQG
RELAFKLGLVGDQIKQFVKIFMGLGQMFSQYDLALLEINPLVITGEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVTVPVVVRLEGTNADLGREVLANSDVDIIAAVSLTDAAQKVVAAAEAK
>Mature_388_residues
MNLHEYQAKQLFAEFGLPVPEGFACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRKIVFMASTEGGVDIEKIAEETPELIHQSAIDPLVGPQAYQG
RELAFKLGLVGDQIKQFVKIFMGLGQMFSQYDLALLEINPLVITGEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVTVPVVVRLEGTNADLGREVLANSDVDIIAAVSLTDAAQKVVAAAEAK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=44.7837150127226, Blast_Score=340, Evalue=1e-93,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.6475195822454, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=45.4038997214485, Blast_Score=306, Evalue=2e-83,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=74.7422680412371, Blast_Score=580, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=45.360824742268, Blast_Score=319, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=41.7302798982188, Blast_Score=301, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=41.8367346938776, Blast_Score=322, Evalue=9e-89,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=43.4010152284264, Blast_Score=307, Evalue=8e-84,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=43.2569974554707, Blast_Score=304, Evalue=6e-83,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=43.2569974554707, Blast_Score=304, Evalue=6e-83,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=43.4010152284264, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=43.4010152284264, Blast_Score=302, Evalue=2e-82,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41516; Mature: 41516

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFAEFGLPVPEGFACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKEFAQKWLGKNLVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRK
EECCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IVFMASTEGGVDIEKIAEETPELIHQSAIDPLVGPQAYQGRELAFKLGLVGDQIKQFVKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FMGLGQMFSQYDLALLEINPLVITGEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
HHHHHHHHHHCCEEEEEECCEEEECCCCEEEECCEEEECCCCCCCCCCHHHHCCCCCHHH
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDDNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVTVPVVVRLEGTNADLGREV
HHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHH
LANSDVDIIAAVSLTDAAQKVVAAAEAK
HCCCCCCEEEEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQAKQLFAEFGLPVPEGFACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKEFAQKWLGKNLVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRK
EECCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IVFMASTEGGVDIEKIAEETPELIHQSAIDPLVGPQAYQGRELAFKLGLVGDQIKQFVKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FMGLGQMFSQYDLALLEINPLVITGEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
HHHHHHHHHHCCEEEEEECCEEEECCCCEEEECCEEEECCCCCCCCCCHHHHCCCCCHHH
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDDNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVTVPVVVRLEGTNADLGREV
HHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHH
LANSDVDIIAAVSLTDAAQKVVAAAEAK
HCCCCCCEEEEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA