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The map label for this gene is znuB [H]

Identifier: 218710207

GI number: 218710207

Start: 2405747

End: 2406532

Strand: Direct

Name: znuB [H]

Synonym: VS_2239

Alternate gene names: 218710207

Gene position: 2405747-2406532 (Clockwise)

Preceding gene: 218710206

Following gene: 218710216

Centisome position: 72.92

GC content: 46.56

Gene sequence:

>786_bases
ATGCTTGAGTTTCTTCTTCCCTCTATTTTAGCTGGCTTGGGCATTGCTCTAATCGCGGGGCCACTAGGTTCATTCGTGGT
GTGGCGCAAGATGGCTTACTTTGGTGACACGCTTGCTCACGCTTCTTTGATGGGCTTAGCACTTGGCTTTCTGTTCAACA
TTAACTTGTATTTCGCGCTGCTGATTTGTTGTTTGATGCTAGCTGTGTTGCTAGTGACTTTACAAAAACAAAAGCTGGTC
GCGACCGATACCCTACTCGGTATTTTGGCGCACAGCGCTCTGTCTTTGGGTCTTGTCGCCGTGAGTTTCTTAGATAACGT
TCGTGTTGACCTAATGAGCTACCTATTTGGTGACTTGCTTGCAGTGTCTCCGACAGATTTGGTATTCATCTATGCGGGTG
CTGCCGTGATTGGAGTGGTACTTGCTATTTTTTGGCGACCACTATTGTCGACGACCGTTAACGAAGATCTCGCAGCGGTT
GATGGCATCAACATTGATTTAATGCGTCTTATTTTGATGCTATTGGTTGGGATCGTGATTGCGGTAGGTATGAAGTTTGT
TGGTGCGTTAATCATGACCTCACTACTTATCATTCCGGCAGCAACGGCAAGAAAATTCGCCAATACACCCGAACAAATGG
CATTCCTTGCATCGGTAATTGGTTCTATCGCTGTGTTCGGAGGATTGAGCTTGTCTTGGTTCTATGACACACCGGCCGGC
CCTTCTGTTGTTATCAGTGCTGCGGCAATGTTTATGTTATCTCAAATGGTTAGAAGCCGAGCTTAG

Upstream 100 bases:

>100_bases
TTTATCACCACCAACACGAACATCACCATCATGATCTCGCAGGACAGCCTGTCGAAGGCGACGTGCATGAATGTTCAAAC
CATAAACACGGACACCACTA

Downstream 100 bases:

>100_bases
CACTTAGCACTTAGCACTTAGCAGGACGATTTCGAATCTCGTATCTCGTATCCCGTATCCCGTATCCCGTATCCCGTATC
CCGAGAACATAAAAAAGGCT

Product: high-affinity zinc uptake system membrane protein ZnuB

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLEFLLPSILAGLGIALIAGPLGSFVVWRKMAYFGDTLAHASLMGLALGFLFNINLYFALLICCLMLAVLLVTLQKQKLV
ATDTLLGILAHSALSLGLVAVSFLDNVRVDLMSYLFGDLLAVSPTDLVFIYAGAAVIGVVLAIFWRPLLSTTVNEDLAAV
DGINIDLMRLILMLLVGIVIAVGMKFVGALIMTSLLIIPAATARKFANTPEQMAFLASVIGSIAVFGGLSLSWFYDTPAG
PSVVISAAAMFMLSQMVRSRA

Sequences:

>Translated_261_residues
MLEFLLPSILAGLGIALIAGPLGSFVVWRKMAYFGDTLAHASLMGLALGFLFNINLYFALLICCLMLAVLLVTLQKQKLV
ATDTLLGILAHSALSLGLVAVSFLDNVRVDLMSYLFGDLLAVSPTDLVFIYAGAAVIGVVLAIFWRPLLSTTVNEDLAAV
DGINIDLMRLILMLLVGIVIAVGMKFVGALIMTSLLIIPAATARKFANTPEQMAFLASVIGSIAVFGGLSLSWFYDTPAG
PSVVISAAAMFMLSQMVRSRA
>Mature_261_residues
MLEFLLPSILAGLGIALIAGPLGSFVVWRKMAYFGDTLAHASLMGLALGFLFNINLYFALLICCLMLAVLLVTLQKQKLV
ATDTLLGILAHSALSLGLVAVSFLDNVRVDLMSYLFGDLLAVSPTDLVFIYAGAAVIGVVLAIFWRPLLSTTVNEDLAAV
DGINIDLMRLILMLLVGIVIAVGMKFVGALIMTSLLIIPAATARKFANTPEQMAFLASVIGSIAVFGGLSLSWFYDTPAG
PSVVISAAAMFMLSQMVRSRA

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=259, Percent_Identity=59.4594594594595, Blast_Score=296, Evalue=7e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 27704; Mature: 27704

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 2842314; 7984428; 9680209 [H]