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The map label for this gene is cdd

Identifier: 218709705

GI number: 218709705

Start: 1843057

End: 1843944

Strand: Direct

Name: cdd

Synonym: VS_1716

Alternate gene names: 218709705

Gene position: 1843057-1843944 (Clockwise)

Preceding gene: 218709704

Following gene: 218709706

Centisome position: 55.86

GC content: 46.51

Gene sequence:

>888_bases
ATGAACAGTCGTATTACCCTGGCGCTGGAAAGTGCTCCAACAGCAATCAAAGCACTTTTGAGTGACATCGTATTAGCAGA
CAACTTTGACGCGACATTGTCTCCAGAACAATTTGCTAGCCTACTGCAAGCAAGTGGTTTAGCGGATGACGAGCTACGTA
TTGCGCTACTTCCTTTTGCCGCAGCCTATTCTTACGCTCCGTTATCTGACTTTTATGTTGGTGCAATCGTGCGTGGTTTG
TCCGGCACTCTGTATTTTGGTGCAAACCTTGAAATCGCTGGTGCTCAACTTGGCCAAACAGTACACGCTGAGCAATCTGC
AATCAGCCACGCTTGGATGAAAGGCGAACAAGGTATTTCTGATATCACCATCAACTTCAGCCCTTGTGGTCACTGTCGTC
AATTCATGAACGAACTGACCACAGCAAAAGAACTTAAAGTTCAGCTTCCACAACGTGATGAAATGTCTCTGCAAGAGTAC
CTACCAGACTCGTTCGGCCCTGCTGATTTAGGTGTGACGACTGGCCTAATGACTAAGCTTGATCATAAACACACGACTGA
AGAAACAACGCCTATTGTTGTAGAAGCGCTAGCAGCACTAAACCGCAGCCATGCTCCTTACACCAAAAACCTAAGTGGTG
TTTCACTGCAATTGACGTCGGGTGAGGTTTTCACTGGTGCTTACGCTGAAAACGCAGCGTTCAACCCGAGCTTACCTCCT
CTGCAAGTGGCGTTGATTCAACTTAAACTGGCTGGCTTCGATTTTGAACAGATTGAAAACGCAGCCTTGGTTGAAATTGC
CGAAGGTAGCATCAGTCACCTAGCGGATACGCAATCTACATTAGAAGCGATTAATCCCGACATTCCAGTGACTTACTTAG
CAATCTAA

Upstream 100 bases:

>100_bases
GCAAACCAATGTAACAACAACAACGCAGTGGTGATCCATGTCACAGAAAATTCCTGAGCATTACATAGAATTAAAGCCTA
AGGTCAATTAAGGATTCAAC

Downstream 100 bases:

>100_bases
GTACATCTGATTAACAAAATTTTAAATAAGCAGCCCTATTTTACAGGGCTGCTTTTTTTATGCTTCTAATTCACACCTCA
ACTTGCGCAAACGTTTGCTT

Product: cytidine deaminase

Products: NA

Alternate protein names: Cytidine aminohydrolase; CDA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNSRITLALESAPTAIKALLSDIVLADNFDATLSPEQFASLLQASGLADDELRIALLPFAAAYSYAPLSDFYVGAIVRGL
SGTLYFGANLEIAGAQLGQTVHAEQSAISHAWMKGEQGISDITINFSPCGHCRQFMNELTTAKELKVQLPQRDEMSLQEY
LPDSFGPADLGVTTGLMTKLDHKHTTEETTPIVVEALAALNRSHAPYTKNLSGVSLQLTSGEVFTGAYAENAAFNPSLPP
LQVALIQLKLAGFDFEQIENAALVEIAEGSISHLADTQSTLEAINPDIPVTYLAI

Sequences:

>Translated_295_residues
MNSRITLALESAPTAIKALLSDIVLADNFDATLSPEQFASLLQASGLADDELRIALLPFAAAYSYAPLSDFYVGAIVRGL
SGTLYFGANLEIAGAQLGQTVHAEQSAISHAWMKGEQGISDITINFSPCGHCRQFMNELTTAKELKVQLPQRDEMSLQEY
LPDSFGPADLGVTTGLMTKLDHKHTTEETTPIVVEALAALNRSHAPYTKNLSGVSLQLTSGEVFTGAYAENAAFNPSLPP
LQVALIQLKLAGFDFEQIENAALVEIAEGSISHLADTQSTLEAINPDIPVTYLAI
>Mature_295_residues
MNSRITLALESAPTAIKALLSDIVLADNFDATLSPEQFASLLQASGLADDELRIALLPFAAAYSYAPLSDFYVGAIVRGL
SGTLYFGANLEIAGAQLGQTVHAEQSAISHAWMKGEQGISDITINFSPCGHCRQFMNELTTAKELKVQLPQRDEMSLQEY
LPDSFGPADLGVTTGLMTKLDHKHTTEETTPIVVEALAALNRSHAPYTKNLSGVSLQLTSGEVFTGAYAENAAFNPSLPP
LQVALIQLKLAGFDFEQIENAALVEIAEGSISHLADTQSTLEAINPDIPVTYLAI

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Escherichia coli, GI1788465, Length=284, Percent_Identity=50, Blast_Score=262, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDD_VIBSL (B7VPF1)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002417326.1
- GeneID:   7161284
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_1716
- HOGENOM:   HBG591160
- OMA:   NRSHAPY
- ProtClustDB:   PRK09027
- HAMAP:   MF_01558
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013171
- InterPro:   IPR006263
- InterPro:   IPR016193
- InterPro:   IPR020797
- PIRSF:   PIRSF006334
- TIGRFAMs:   TIGR01355

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF08211 dCMP_cyt_deam_2; SSF53927 Cytidine_deaminase-like

EC number: =3.5.4.5

Molecular weight: Translated: 31552; Mature: 31552

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRITLALESAPTAIKALLSDIVLADNFDATLSPEQFASLLQASGLADDELRIALLPFA
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHH
AAYSYAPLSDFYVGAIVRGLSGTLYFGANLEIAGAQLGQTVHAEQSAISHAWMKGEQGIS
HHHCCCCHHHHHHHHHHHHCCCEEEECCCEEECCHHHCCHHHHHHHHHHHHHHCCCCCCC
DITINFSPCGHCRQFMNELTTAKELKVQLPQRDEMSLQEYLPDSFGPADLGVTTGLMTKL
EEEEECCCCHHHHHHHHHHCCHHHHHEECCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHH
DHKHTTEETTPIVVEALAALNRSHAPYTKNLSGVSLQLTSGEVFTGAYAENAAFNPSLPP
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCCH
LQVALIQLKLAGFDFEQIENAALVEIAEGSISHLADTQSTLEAINPDIPVTYLAI
HHHHEEEHHHCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MNSRITLALESAPTAIKALLSDIVLADNFDATLSPEQFASLLQASGLADDELRIALLPFA
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHH
AAYSYAPLSDFYVGAIVRGLSGTLYFGANLEIAGAQLGQTVHAEQSAISHAWMKGEQGIS
HHHCCCCHHHHHHHHHHHHCCCEEEECCCEEECCHHHCCHHHHHHHHHHHHHHCCCCCCC
DITINFSPCGHCRQFMNELTTAKELKVQLPQRDEMSLQEYLPDSFGPADLGVTTGLMTKL
EEEEECCCCHHHHHHHHHHCCHHHHHEECCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHH
DHKHTTEETTPIVVEALAALNRSHAPYTKNLSGVSLQLTSGEVFTGAYAENAAFNPSLPP
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCCH
LQVALIQLKLAGFDFEQIENAALVEIAEGSISHLADTQSTLEAINPDIPVTYLAI
HHHHEEEHHHCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA