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The map label for this gene is erg3 [H]

Identifier: 218709701

GI number: 218709701

Start: 1839214

End: 1840062

Strand: Direct

Name: erg3 [H]

Synonym: VS_1712

Alternate gene names: 218709701

Gene position: 1839214-1840062 (Clockwise)

Preceding gene: 218709700

Following gene: 218709702

Centisome position: 55.75

GC content: 45.82

Gene sequence:

>849_bases
ATGAATATCGACGCATTAATCAATCACCCAGAATGGCTACTGCTGGTATTAGCGCCCTTATTCATGGTGTGCATGGCGGC
TGAGTATTTTATCGGTCAGAAGCAAGGTCGACTGCCAGATAACTCCAGCTATAAACTTTCAGAAGTGATGTGTAACTTCA
CGCTTGCGGGAATGCATCAACTCTCGGATTTGCTCACCGGGTTATTGGTCGTGCAGTTGTATCTTTGGCTGTTTGGTTGG
CGCTTAATGGACGTTGAAATGGGCGTACTGAGTTTTGTTGTATTGATGGTATTACAAGACTTTTGCTATTACTGGTTCCA
TAGAGCAAGCCATCGTGTTCGCTGGATGTGGGCCGCGCACGTCGCGCACCACAGTTCAGAAAGCATGAACTTCAGTACGG
CTTTCCGTCAGAGTTTTATGTATCCACTTGCTGGGATGTGGCTGTTCTGGGTGCCGCTGGTCATCATAGGTTTCGACCCT
AAATGGGTGATCTTTGTGGTCCTTCTCAACCTAGGTTTGCAGTTCTTCGTCCATACACAATGGATACGAAGCTTGGGGCC
ACTGGAATACATCTTCAACACCCCTTCACATCATCGAGTGCATCACGGCAAAAACCCGCAATACATAGATAAGAACTACG
CCGGCGTTTTAATCATTTGGGATAAATTGTTTGGTACGTTCGAGCCTGAAATTGAAACCGTGCGTTACGGCGTCACCAAA
CCCGTAAACAGTTTTAACCCTATAATCGTCACCTTTCAAGAATGGAAGGCTATATTCAAAGATTTGAGAAACCGAGAGCT
AACCATTAAACAGAAAGTCCAGTTGATACTCTCACCCCCATCGGATTAA

Upstream 100 bases:

>100_bases
CGCTCGCTGGTAGCGTAATTCTGCTGATTGAATCTCAGGCGAGCAAGTCTAAGTAAACTTGATACTAAGAACGCGTATGG
CGTCTCAACAAGGATAAAAC

Downstream 100 bases:

>100_bases
ACGGACGATAGACAGATTGTATTAACTAAGATACCGCCTCAACTGGATTCAAAGACATCCCCACCGACTCGATTGAATAG
TAAAGCACCGTTTTCCGACA

Product: sterol desaturase family protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNIDALINHPEWLLLVLAPLFMVCMAAEYFIGQKQGRLPDNSSYKLSEVMCNFTLAGMHQLSDLLTGLLVVQLYLWLFGW
RLMDVEMGVLSFVVLMVLQDFCYYWFHRASHRVRWMWAAHVAHHSSESMNFSTAFRQSFMYPLAGMWLFWVPLVIIGFDP
KWVIFVVLLNLGLQFFVHTQWIRSLGPLEYIFNTPSHHRVHHGKNPQYIDKNYAGVLIIWDKLFGTFEPEIETVRYGVTK
PVNSFNPIIVTFQEWKAIFKDLRNRELTIKQKVQLILSPPSD

Sequences:

>Translated_282_residues
MNIDALINHPEWLLLVLAPLFMVCMAAEYFIGQKQGRLPDNSSYKLSEVMCNFTLAGMHQLSDLLTGLLVVQLYLWLFGW
RLMDVEMGVLSFVVLMVLQDFCYYWFHRASHRVRWMWAAHVAHHSSESMNFSTAFRQSFMYPLAGMWLFWVPLVIIGFDP
KWVIFVVLLNLGLQFFVHTQWIRSLGPLEYIFNTPSHHRVHHGKNPQYIDKNYAGVLIIWDKLFGTFEPEIETVRYGVTK
PVNSFNPIIVTFQEWKAIFKDLRNRELTIKQKVQLILSPPSD
>Mature_282_residues
MNIDALINHPEWLLLVLAPLFMVCMAAEYFIGQKQGRLPDNSSYKLSEVMCNFTLAGMHQLSDLLTGLLVVQLYLWLFGW
RLMDVEMGVLSFVVLMVLQDFCYYWFHRASHRVRWMWAAHVAHHSSESMNFSTAFRQSFMYPLAGMWLFWVPLVIIGFDP
KWVIFVVLLNLGLQFFVHTQWIRSLGPLEYIFNTPSHHRVHHGKNPQYIDKNYAGVLIIWDKLFGTFEPEIETVRYGVTK
PVNSFNPIIVTFQEWKAIFKDLRNRELTIKQKVQLILSPPSD

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=155, Percent_Identity=59.3548387096774, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25144659, Length=273, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 33073; Mature: 33073

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCEEEEHHHHHHHHHHHCCCCEEHHHHEEEEECCCCC
>Mature Secondary Structure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CCCCCCCEEEEHHHHHHHHHHHCCCCEEHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]