BacMap

Definition	Vibrio splendidus LGP32 chromosome 1, complete genome.
Accession	NC_011753
Length	3,299,303

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The map label for this gene is btuD

Identifier: 218709684

GI number: 218709684

Start: 1820429

End: 1821187

Strand: Reverse

Name: btuD

Synonym: VS_1695

Alternate gene names: 218709684

Gene position: 1821187-1820429 (Counterclockwise)

Preceding gene: 218709685

Following gene: 218709683

Centisome position: 55.2

GC content: 47.04

Gene sequence:

>759_bases
ATGATTCAAATTAAGAGCCTGAGCGTCGGCGCTCGTTTATTACCACTATCATTTGAGCTCAAGCAAGGGCAGGTGACTCA
TGTCATCGGTCCTAATGGCAGTGGAAAAAGTACCTTATTAGAAGCGATATCTGGCGTCGGTGATGGCTACAAAGGTGATA
TAAAGCTCGACGGGCAGGATTTGTCTGAACTGTCTCTACAAGATTTATCATTGCATCGTGCTTATTTGTGCCAAAGCGCA
AGGCCAGCCTTTAACTTGGAAGTGTTCCAATACCTTGCGTTGTCACTGCCAAGTTCATCACACGGCCTTGATATTGAAAT
CAACGCAGCTTTGGACGAAATCAGCCAGATGCTAGACATCTCAGACAAACTTCATCGTTCAATTCAGACATTGTCTGGTG
GTGAATGGCAACGCGTTCGCTTGGCGGGCATGTGTCTGCAAATTTGGCCGACGCTTAATCCATACGCAAAGCTGCTGATC
CTCGATGAACCCGCAGCTCCATTGGATATTGCTCAAGAAGCCTTGTTATACAAGCTCATTGAACGAGTGGCAGAGAAGGG
CATCGCCGTGATCATGGCTAACCACGACCTGAACCGGACCTTGAGGCATGCCGACCAAGTACTGCTGCTCGAAAAGGGCG
TACTACAAACATCAGGCAGTGCAGAGCAAGTGCTTGTGCCTGAACAGCTAGAATCCGTATTTAACACGCAAGTAAAAAGC
ATCTCGGTCGACAATCAAACTTATCTATTGTTTGGTTAA

Upstream 100 bases:

>100_bases
ATTTGTGCAAGAACTTTATTAGATTCTGCAGAATTACCCTTGGGTGTGATGACCACCAGTATCGGTGCACCAATCTTCAT
TTGGATGTTAATTAAAAATC

Downstream 100 bases:

>100_bases
CTTAGGCTCATCAATACAAGGCAATCTCTTTGTTTAGATATATTCAACGACGACGAATCAAGAAAGTAATCAAATCACTT
TCTGCAAAGTTGGTGAAAGC

Product: putative vitamin B12 ABC transporterATP-binding protein BtuD

Products: NA

Alternate protein names: Vitamin B12-transporting ATPase

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MIQIKSLSVGARLLPLSFELKQGQVTHVIGPNGSGKSTLLEAISGVGDGYKGDIKLDGQDLSELSLQDLSLHRAYLCQSA
RPAFNLEVFQYLALSLPSSSHGLDIEINAALDEISQMLDISDKLHRSIQTLSGGEWQRVRLAGMCLQIWPTLNPYAKLLI
LDEPAAPLDIAQEALLYKLIERVAEKGIAVIMANHDLNRTLRHADQVLLLEKGVLQTSGSAEQVLVPEQLESVFNTQVKS
ISVDNQTYLLFG

Sequences:

>Translated_252_residues
MIQIKSLSVGARLLPLSFELKQGQVTHVIGPNGSGKSTLLEAISGVGDGYKGDIKLDGQDLSELSLQDLSLHRAYLCQSA
RPAFNLEVFQYLALSLPSSSHGLDIEINAALDEISQMLDISDKLHRSIQTLSGGEWQRVRLAGMCLQIWPTLNPYAKLLI
LDEPAAPLDIAQEALLYKLIERVAEKGIAVIMANHDLNRTLRHADQVLLLEKGVLQTSGSAEQVLVPEQLESVFNTQVKS
ISVDNQTYLLFG
>Mature_252_residues
MIQIKSLSVGARLLPLSFELKQGQVTHVIGPNGSGKSTLLEAISGVGDGYKGDIKLDGQDLSELSLQDLSLHRAYLCQSA
RPAFNLEVFQYLALSLPSSSHGLDIEINAALDEISQMLDISDKLHRSIQTLSGGEWQRVRLAGMCLQIWPTLNPYAKLLI
LDEPAAPLDIAQEALLYKLIERVAEKGIAVIMANHDLNRTLRHADQVLLLEKGVLQTSGSAEQVLVPEQLESVFNTQVKS
ISVDNQTYLLFG

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system

COG id: COG4138

COG function: function code H; ABC-type cobalamin transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI9955968, Length=217, Percent_Identity=29.4930875576037, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI9955966, Length=217, Percent_Identity=29.4930875576037, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI45243524, Length=217, Percent_Identity=29.4930875576037, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI171184400, Length=221, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI42741659, Length=217, Percent_Identity=26.2672811059908, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI9955963, Length=222, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788002, Length=250, Percent_Identity=41.6, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1786345, Length=237, Percent_Identity=32.9113924050633, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790739, Length=230, Percent_Identity=30, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786803, Length=224, Percent_Identity=28.125, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1788761, Length=213, Percent_Identity=27.6995305164319, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082268, Length=227, Percent_Identity=28.1938325991189, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788165, Length=235, Percent_Identity=31.4893617021277, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789873, Length=227, Percent_Identity=31.2775330396476, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787029, Length=218, Percent_Identity=27.5229357798165, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48995001, Length=207, Percent_Identity=28.0193236714976, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081709, Length=211, Percent_Identity=27.9620853080569, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790162, Length=212, Percent_Identity=28.7735849056604, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081791, Length=210, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786698, Length=197, Percent_Identity=30.4568527918782, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790525, Length=217, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787792, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788450, Length=207, Percent_Identity=27.0531400966184, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787370, Length=223, Percent_Identity=23.7668161434978, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789991, Length=218, Percent_Identity=29.3577981651376, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786398, Length=215, Percent_Identity=27.906976744186, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787143, Length=221, Percent_Identity=27.1493212669683, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790190, Length=221, Percent_Identity=24.8868778280543, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1790467, Length=206, Percent_Identity=24.7572815533981, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693107, Length=231, Percent_Identity=29.004329004329, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081834, Length=199, Percent_Identity=28.1407035175879, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789891, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082267, Length=224, Percent_Identity=25.8928571428571, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789593, Length=223, Percent_Identity=26.9058295964126, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786703, Length=210, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789032, Length=238, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786981, Length=224, Percent_Identity=30.3571428571429, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788897, Length=225, Percent_Identity=24.4444444444444, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790544, Length=235, Percent_Identity=24.6808510638298, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786253, Length=219, Percent_Identity=27.3972602739726, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789890, Length=223, Percent_Identity=28.6995515695067, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787547, Length=218, Percent_Identity=27.9816513761468, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081782, Length=210, Percent_Identity=27.1428571428571, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787105, Length=232, Percent_Identity=24.5689655172414, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1788506, Length=231, Percent_Identity=29.4372294372294, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71992285, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17567269, Length=218, Percent_Identity=27.9816513761468, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=241, Percent_Identity=27.3858921161826, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=234, Percent_Identity=27.3504273504274, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193211015, Length=219, Percent_Identity=27.8538812785388, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193208177, Length=224, Percent_Identity=27.6785714285714, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193202349, Length=215, Percent_Identity=27.4418604651163, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=216, Percent_Identity=26.8518518518519, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567265, Length=215, Percent_Identity=29.7674418604651, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=217, Percent_Identity=27.6497695852535, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115535101, Length=218, Percent_Identity=27.0642201834862, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=213, Percent_Identity=27.2300469483568, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=216, Percent_Identity=26.3888888888889, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=213, Percent_Identity=26.2910798122066, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=202, Percent_Identity=26.2376237623762, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71996550, Length=230, Percent_Identity=26.9565217391304, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=241, Percent_Identity=25.3112033195021, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115534520, Length=220, Percent_Identity=24.5454545454545, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322640, Length=231, Percent_Identity=29.8701298701299, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323959, Length=218, Percent_Identity=25.2293577981651, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357907, Length=217, Percent_Identity=28.110599078341, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24666092, Length=210, Percent_Identity=27.6190476190476, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85724864, Length=216, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24580555, Length=216, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI85816269, Length=216, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24580553, Length=216, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28574744, Length=217, Percent_Identity=27.6497695852535, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24662800, Length=207, Percent_Identity=28.5024154589372, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BTUD_VIBSL (B7VPD0)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002417305.1
- ProteinModelPortal:   B7VPD0
- GeneID:   7161263
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_1695
- HOGENOM:   HBG758042
- OMA:   IAVIMAN
- HAMAP:   MF_01005
- InterPro:   IPR003439
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.33

Molecular weight: Translated: 27582; Mature: 27582

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIKSLSVGARLLPLSFELKQGQVTHVIGPNGSGKSTLLEAISGVGDGYKGDIKLDGQD
CEEEEEECCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEECCCC
LSELSLQDLSLHRAYLCQSARPAFNLEVFQYLALSLPSSSHGLDIEINAALDEISQMLDI
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
SDKLHRSIQTLSGGEWQRVRLAGMCLQIWPTLNPYAKLLILDEPAAPLDIAQEALLYKLI
HHHHHHHHHHCCCCCEEEHHHHHHHHEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
ERVAEKGIAVIMANHDLNRTLRHADQVLLLEKGVLQTSGSAEQVLVPEQLESVFNTQVKS
HHHHHCCEEEEEECCCHHHHHHHHHHEEEHHCCCCCCCCCCCEEECHHHHHHHHHHHHHE
ISVDNQTYLLFG
EEECCEEEEEEC
>Mature Secondary Structure
MIQIKSLSVGARLLPLSFELKQGQVTHVIGPNGSGKSTLLEAISGVGDGYKGDIKLDGQD
CEEEEEECCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEECCCC
LSELSLQDLSLHRAYLCQSARPAFNLEVFQYLALSLPSSSHGLDIEINAALDEISQMLDI
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
SDKLHRSIQTLSGGEWQRVRLAGMCLQIWPTLNPYAKLLILDEPAAPLDIAQEALLYKLI
HHHHHHHHHHCCCCCEEEHHHHHHHHEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
ERVAEKGIAVIMANHDLNRTLRHADQVLLLEKGVLQTSGSAEQVLVPEQLESVFNTQVKS
HHHHHCCEEEEEECCCHHHHHHHHHHEEEHHCCCCCCCCCCCEEECHHHHHHHHHHHHHE
ISVDNQTYLLFG
EEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA