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The map label for this gene is nahR [H]

Identifier: 218709624

GI number: 218709624

Start: 1753339

End: 1754274

Strand: Reverse

Name: nahR [H]

Synonym: VS_1634

Alternate gene names: 218709624

Gene position: 1754274-1753339 (Counterclockwise)

Preceding gene: 218709625

Following gene: 218709623

Centisome position: 53.17

GC content: 45.09

Gene sequence:

>936_bases
TTGAATATCCTTATAATGAATCTTGCCCAGGTCGACCTTAACCTACTCGTTATTCTTAAACACCTTCTTGAAGAGAAGCA
CGTATCAAACACAGCCTTGGCGTTGGACATGAGCCAACCGACGGTGAGTCGTTCACTACAAAAACTACGAACGGTATTCA
ACGATGACTTGTTAGTCCGCGCAGCCTATGGGTATGAGTTAACTCCGAAAGCAGAAGTCATCAAGCAAGACCTCAACTCT
GTGCTCACACGCCTTGAGAAATTGGTCCATGGAGACGTATTTGAACCGCAGACGAGCAATAGTACCGTTCGGTTCTTTGG
CTTGGTTCCGCAAGTCTCGCATTTGTTACCAAAAGTGGTGGCACAAATCCGCAAGCAAGCGCCGAATATGGTTGTCGATA
TCGACTCGATTCCTAAACGACACTTTGAACCTCTGTTATCAGGTGATGCGCACTTTGTATTGTCGACGCATGAACCATTA
AGTTCTGAACAAAACTTGTATCGAATGTTCGTAATCAGTCGCGACTATCGGTTATTGATGAGCAAAGACCACCCTCTGGC
GGATAAAGAGATCACCGTTGATGATTTATTGAGTAGCCAACTCGGCCAGATCTCACTGCAAGGGGATAAGAAGCTCTCGA
TTGAAAGTCGTTTCAAAGATTTGGGCTTGATCGATAAGCAGCGTCAGCTATCGATACCGATTCAACTGTCTAACTTTAAC
GTCGCTCCAGATATGGCTGAAGCGACCGATATCATCTTTCACCTGCCGACACCTTTCGCTCAACAAGCAGCAAAACAAAG
AAACCTTGTTTGTAAACGCGTACCCAAAGCGATCAGGAGCCCATCAGAAGACGTATATCTCTACTGGCATAAACGTTTCC
ACAATGACCCTATGTGTCGTTGGATTCGTGAACTATTTAAAGAGACATACTCCTAA

Upstream 100 bases:

>100_bases
AATTCGGCACTTCACATTGTATGACATCAAAGTAAGAGTGATTATCAATTGTATTAATTCTGGGGAAATAGCACTATACG
CATATTGAATCTTCAGCATT

Downstream 100 bases:

>100_bases
ATTATCTGGCACATGAATGCTACTGGCTTAATGCTAATGAATTGAATATATGTTGTCTGCATTATTTGATAAATGAATAA
TCATAATGAATTTTCAGCAT

Product: putative LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNILIMNLAQVDLNLLVILKHLLEEKHVSNTALALDMSQPTVSRSLQKLRTVFNDDLLVRAAYGYELTPKAEVIKQDLNS
VLTRLEKLVHGDVFEPQTSNSTVRFFGLVPQVSHLLPKVVAQIRKQAPNMVVDIDSIPKRHFEPLLSGDAHFVLSTHEPL
SSEQNLYRMFVISRDYRLLMSKDHPLADKEITVDDLLSSQLGQISLQGDKKLSIESRFKDLGLIDKQRQLSIPIQLSNFN
VAPDMAEATDIIFHLPTPFAQQAAKQRNLVCKRVPKAIRSPSEDVYLYWHKRFHNDPMCRWIRELFKETYS

Sequences:

>Translated_311_residues
MNILIMNLAQVDLNLLVILKHLLEEKHVSNTALALDMSQPTVSRSLQKLRTVFNDDLLVRAAYGYELTPKAEVIKQDLNS
VLTRLEKLVHGDVFEPQTSNSTVRFFGLVPQVSHLLPKVVAQIRKQAPNMVVDIDSIPKRHFEPLLSGDAHFVLSTHEPL
SSEQNLYRMFVISRDYRLLMSKDHPLADKEITVDDLLSSQLGQISLQGDKKLSIESRFKDLGLIDKQRQLSIPIQLSNFN
VAPDMAEATDIIFHLPTPFAQQAAKQRNLVCKRVPKAIRSPSEDVYLYWHKRFHNDPMCRWIRELFKETYS
>Mature_311_residues
MNILIMNLAQVDLNLLVILKHLLEEKHVSNTALALDMSQPTVSRSLQKLRTVFNDDLLVRAAYGYELTPKAEVIKQDLNS
VLTRLEKLVHGDVFEPQTSNSTVRFFGLVPQVSHLLPKVVAQIRKQAPNMVVDIDSIPKRHFEPLLSGDAHFVLSTHEPL
SSEQNLYRMFVISRDYRLLMSKDHPLADKEITVDDLLSSQLGQISLQGDKKLSIESRFKDLGLIDKQRQLSIPIQLSNFN
VAPDMAEATDIIFHLPTPFAQQAAKQRNLVCKRVPKAIRSPSEDVYLYWHKRFHNDPMCRWIRELFKETYS

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=301, Percent_Identity=26.9102990033223, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790147, Length=306, Percent_Identity=22.2222222222222, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35660; Mature: 35660

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILIMNLAQVDLNLLVILKHLLEEKHVSNTALALDMSQPTVSRSLQKLRTVFNDDLLVR
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEE
AAYGYELTPKAEVIKQDLNSVLTRLEKLVHGDVFEPQTSNSTVRFFGLVPQVSHLLPKVV
EECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHH
AQIRKQAPNMVVDIDSIPKRHFEPLLSGDAHFVLSTHEPLSSEQNLYRMFVISRDYRLLM
HHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEEECCHHEEE
SKDHPLADKEITVDDLLSSQLGQISLQGDKKLSIESRFKDLGLIDKQRQLSIPIQLSNFN
CCCCCCCCCCCCHHHHHHHHHCCEEECCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCCC
VAPDMAEATDIIFHLPTPFAQQAAKQRNLVCKRVPKAIRSPSEDVYLYWHKRFHNDPMCR
CCCCHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCHHHH
WIRELFKETYS
HHHHHHHHHCC
>Mature Secondary Structure
MNILIMNLAQVDLNLLVILKHLLEEKHVSNTALALDMSQPTVSRSLQKLRTVFNDDLLVR
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEE
AAYGYELTPKAEVIKQDLNSVLTRLEKLVHGDVFEPQTSNSTVRFFGLVPQVSHLLPKVV
EECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHH
AQIRKQAPNMVVDIDSIPKRHFEPLLSGDAHFVLSTHEPLSSEQNLYRMFVISRDYRLLM
HHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEEECCHHEEE
SKDHPLADKEITVDDLLSSQLGQISLQGDKKLSIESRFKDLGLIDKQRQLSIPIQLSNFN
CCCCCCCCCCCCHHHHHHHHHCCEEECCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCCC
VAPDMAEATDIIFHLPTPFAQQAAKQRNLVCKRVPKAIRSPSEDVYLYWHKRFHNDPMCR
CCCCHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCHHHH
WIRELFKETYS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]