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The map label for this gene is fabA [H]

Identifier: 218709420

GI number: 218709420

Start: 1571485

End: 1572006

Strand: Reverse

Name: fabA [H]

Synonym: VS_1429

Alternate gene names: 218709420

Gene position: 1572006-1571485 (Counterclockwise)

Preceding gene: 218709421

Following gene: 218709405

Centisome position: 47.65

GC content: 45.02

Gene sequence:

>522_bases
TTGATAATGCAAAACAAACGTGATTCTTACACTCGCGAAGATCTTCTAGCATCAAGCCAAGGCGAACTATGGCCTGAAGG
TCCTCAACTACCAGCACCGAACATGTTGATGATGGATCGCATCACTAAAATGTCTGAGACTGAAGGTGATTTCGGTAAAG
GTTTGATTCTTGCTGAACTGGATATTACTCCTGACCTATGGTTCTTCGACTGTCACTTCCCTGGTGACCCAGTAATGCCT
GGTTGTCTAGGACTTGATGCAATGTGGCAGCTTGTTGGCTTCTACCTTGGTTGGGTTGGCGGCAAAGGTAAAGGCCGTGC
TTTAGGTGTAGGCGAAGTGAAATTCACTGGCCAAATCCTACCTACTGCGAAAAAAGTGACTTACGAAATCCACATGAAGC
GTGTTGTTAACCGTCGCCTAGTTATGGGCCTTGCAGATGGTCGCGTACTTGTTGATGGCAAAGAGATTTATGTTGCTAAA
GATTTGAAAGTTGGTCTTTTCCAAGATACGTCAGCATTCTAA

Upstream 100 bases:

>100_bases
GGAATTGTTGGACGCATTAAAAACTGGTTTGTCTAGTACTGATCGGACTTGTTTAGCGTACACCTGTTCACTAATATGCA
CCTATCAAAAATTGGAGTAA

Downstream 100 bases:

>100_bases
TCCAACTGTTTAATTAGAATAAAGCAGTTAGATTTTAATAAAGCAGCCAATGGCTGCTTTATTTTCACTCCAATATATTT
AGTTATAGTGCATTATAATG

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MIMQNKRDSYTREDLLASSQGELWPEGPQLPAPNMLMMDRITKMSETEGDFGKGLILAELDITPDLWFFDCHFPGDPVMP
GCLGLDAMWQLVGFYLGWVGGKGKGRALGVGEVKFTGQILPTAKKVTYEIHMKRVVNRRLVMGLADGRVLVDGKEIYVAK
DLKVGLFQDTSAF

Sequences:

>Translated_173_residues
MIMQNKRDSYTREDLLASSQGELWPEGPQLPAPNMLMMDRITKMSETEGDFGKGLILAELDITPDLWFFDCHFPGDPVMP
GCLGLDAMWQLVGFYLGWVGGKGKGRALGVGEVKFTGQILPTAKKVTYEIHMKRVVNRRLVMGLADGRVLVDGKEIYVAK
DLKVGLFQDTSAF
>Mature_173_residues
MIMQNKRDSYTREDLLASSQGELWPEGPQLPAPNMLMMDRITKMSETEGDFGKGLILAELDITPDLWFFDCHFPGDPVMP
GCLGLDAMWQLVGFYLGWVGGKGKGRALGVGEVKFTGQILPTAKKVTYEIHMKRVVNRRLVMGLADGRVLVDGKEIYVAK
DLKVGLFQDTSAF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=172, Percent_Identity=80.2325581395349, Blast_Score=286, Evalue=4e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 19243; Mature: 19243

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMQNKRDSYTREDLLASSQGELWPEGPQLPAPNMLMMDRITKMSETEGDFGKGLILAEL
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEE
DITPDLWFFDCHFPGDPVMPGCLGLDAMWQLVGFYLGWVGGKGKGRALGVGEVKFTGQIL
CCCCCEEEEEEECCCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECEEC
PTAKKVTYEIHMKRVVNRRLVMGLADGRVLVDGKEIYVAKDLKVGLFQDTSAF
CCCHHHHHHHHHHHHHHHHEEEEECCCEEEEECCEEEEEECCEEEEECCCCCC
>Mature Secondary Structure
MIMQNKRDSYTREDLLASSQGELWPEGPQLPAPNMLMMDRITKMSETEGDFGKGLILAEL
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEE
DITPDLWFFDCHFPGDPVMPGCLGLDAMWQLVGFYLGWVGGKGKGRALGVGEVKFTGQIL
CCCCCEEEEEEECCCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECEEC
PTAKKVTYEIHMKRVVNRRLVMGLADGRVLVDGKEIYVAKDLKVGLFQDTSAF
CCCHHHHHHHHHHHHHHHHEEEEECCCEEEEECCEEEEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA