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The map label for this gene is pepN [H]

Identifier: 218709410

GI number: 218709410

Start: 1554037

End: 1556643

Strand: Direct

Name: pepN [H]

Synonym: VS_1419

Alternate gene names: 218709410

Gene position: 1554037-1556643 (Clockwise)

Preceding gene: 218709409

Following gene: 218709411

Centisome position: 47.1

GC content: 44.99

Gene sequence:

>2607_bases
ATGGCACATACACCTCAAGCCAAGTATCGTAAAGATTATCAATCACCATCTCACACTATTTCTCAAATCGATCTTACTTT
CGATTTGTACGATTCAGCGTCCATTATTACGGCGGTGTCTAGTGTTAAGCAAGAGAAAGATAGTTCGACCTTAGTACTTG
ATGGTGAAGGTTTGACGTTGGTTTCTGTTTTAGTTGAGGGTCAAGAGTGGACGCAATTCGAGCAATCTGAAACTCAACTG
ACACTGAGCGGACTACCGAAAGATTTCACACTCACGATCGTGACGGAAGTTAATCCTGAAGGGAATAGTGCACTTGAAGG
TTTGTATAAGTCGGGTGGCGCATTCTGTACTCAGTGTGAAGCTGAAGGTTTCCGTCGTATTACTTACTACATGGACCGCC
CTGATGTATTGGCAAAATTCACCACAACGGTAATCGCAGACAAAGCAGAAAATCCATTCTTACTAAGTAATGGTAACCGT
GTAGATGAAGGTGAAGCTGAAAACGGTCGTCACTGGGTGAAATGGCAAGACCCACATCCAAAACCAGCGTACTTGTTTGC
TTTAGTTGCGGGTGACTTTGATGTACTTCGTGACGCTTACACCACTCAATCAGGCCGTAAAGTTGATCTAGAAATCTTTG
TCGACAAAGGCAATCTAGACCGCGCAAACCACGCGATGGTTTCTTTGATTAACTCAATGAAGTGGGACGAAGAGCGTTTC
AATCTTGAGTATGACTTAGACATCTACATGATCGTAGCTGTTGATTTCTTCAACATGGGCGCGATGGAAAACAAAGGTCT
GAACGTATTTAACTCTAAGTTTGTTTTAGCGAACGACCAAACAGCAACCGACACCGACTACCTAGGCATCGAAGCGGTAA
TCGGTCATGAATATTTCCATAACTGGACCGGTAACCGAGTGACATGTCGCGATTGGTTCCAACTAAGCTTGAAAGAAGGC
TTAACCGTATTCCGTGACCAAGAGTTCTCATCTGATCTTGGTTCTCGCGCAGTAAACCGAATCAACAATGTTCGTATTAT
TCGCGGGCCACAATTCGCTGAAGATGCAAGTCCAATGTCTCACCCAATTCGCCCTGAAAAAGTGATAGAAATGAACAACT
TCTACACATTGACTGTATACGAAAAGGGCAGTGAAGTGATCCGAATGATCCACACATTGTTGGGTGAGGAAGGTTTCCAA
AAAGGCATGAAGCTTTACTTTGAACGTCACGATGGTACCGCTGCAACTTGCGAAGATTTCGTTGCTGCAATGGAAGATGC
GTCGGGCGTTGACCTGTCTCAGTTCCGTTTATGGTACAGCCAGTCTGGTACGCCGACGCTGTCTGTTGAAAGTCACTACA
ACGCAGAAAAGAAAGAGTACACGTTAACAACTCGCCAAGTAACGGCTCCAACTCATGAGCAAACGGATAAGCAAGCTCTG
CATATTCCTCTAGACATCGAGCTATACACCGCGTCGGGTGAAGTGATTGGGTTACAATGTAACGGTCAGCCAGTTCACAA
TGTATTAGATGTGAAAGAAGCGGAACAAACGTTTGTGTTTGAAAACGTTTCAGAGCAACCGATCCCATCGCTACTTCGTG
AATTCTCTGCGCCAGTGAAATTGGAATACGATTACTCAGATGAAGAGCTGATCTTCTTGATGGTGAATGCTCGCAATGAG
TTCTCTCGTTGGGATGCGGGTCAAATGCTGCTAGCGAAATACATCCGTAGCAACGTAGATAACGTTCAACAAGGTCAAAA
GTTTGAACTTTCTGCTTCTGTTGTTGATGCATTCCGTGGGGTACTGCTTAGTGATTCACTAGAACCTGCGTTTATTGCAG
AAATGCTGTCTCTTCCAAGTCATAACGAAGTGTCGGGTTGGTATGAGCGCGTTGATATTGATGCGGTCGCATCTGTTCTT
AACTCCATGAAAGTAACACTAGCTGCAGAACTTGAAGACGAGTTAGCGGCGGTTTATCACAGCCATGCACTAACAGAATA
CACGATCGATCACGATTCGATTGGTAAGCGTACTCTACGTAAAGTTTGTCTAAGTTACTTAGCGCATACTGAAAAGGGTA
ATGACTTGGTTGTTGCTATGTACCAACAAGCAAACAACATGACAGACACAATGGCAGCGATGGGCGCGGCGAACAGTGCG
CAACTACCATGTCGTGAAACCTTGATGGCGGATTACAGCGACAAGTGGAAACACGATGGTCTTGTCATGGATAAGTGGTT
TGCATTGCAAGGTTCAAACCCAAGCTCTAATGCACTTGAAGTGATTAAAGCGTCGATGTCGCACCAAGCGTTCAGCTTGA
AGAACCCGAACCGTACTCGTAACTTGGTAGGTTCGTTCTTAAACATGAACCCGGTTCAATTCCACGCCAAGTCAGGACAA
GGTTATGCGTTTGCGGGCGAGATCCTACGTGAACTGAACAGCAGCAACCCGCAAGTGGCTTCACGTTTGATTGACCCGCT
ACTTAAGTTCCGTAAGTACGATGATGAACGCCAAGCTCTAATCAAAAAAGAACTTGAGACGCTGAAGAACATGGACAACC
TTGCAAAAGACTTATTCGAGAAAGTGGCAAAAGCACTAGAGGCTTAA

Upstream 100 bases:

>100_bases
TGCCTCCTTTTTTCAATATTCCCCTTGTGTTCTTGGCCCTCAACCTTTAGATATATACAGTTAAAATACAATTACGTATA
ACGATCAAAAGGAACCCGTC

Downstream 100 bases:

>100_bases
ATCAGCCGCTTATTCAGGTAACTGTTTGATCATAAGCGGTTTGCTAATAAACAGTTTACTAGTAACGAAAAGTCATCAGT
GGTAGAGAATATCTGCCACT

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 868; Mature: 867

Protein sequence:

>868_residues
MAHTPQAKYRKDYQSPSHTISQIDLTFDLYDSASIITAVSSVKQEKDSSTLVLDGEGLTLVSVLVEGQEWTQFEQSETQL
TLSGLPKDFTLTIVTEVNPEGNSALEGLYKSGGAFCTQCEAEGFRRITYYMDRPDVLAKFTTTVIADKAENPFLLSNGNR
VDEGEAENGRHWVKWQDPHPKPAYLFALVAGDFDVLRDAYTTQSGRKVDLEIFVDKGNLDRANHAMVSLINSMKWDEERF
NLEYDLDIYMIVAVDFFNMGAMENKGLNVFNSKFVLANDQTATDTDYLGIEAVIGHEYFHNWTGNRVTCRDWFQLSLKEG
LTVFRDQEFSSDLGSRAVNRINNVRIIRGPQFAEDASPMSHPIRPEKVIEMNNFYTLTVYEKGSEVIRMIHTLLGEEGFQ
KGMKLYFERHDGTAATCEDFVAAMEDASGVDLSQFRLWYSQSGTPTLSVESHYNAEKKEYTLTTRQVTAPTHEQTDKQAL
HIPLDIELYTASGEVIGLQCNGQPVHNVLDVKEAEQTFVFENVSEQPIPSLLREFSAPVKLEYDYSDEELIFLMVNARNE
FSRWDAGQMLLAKYIRSNVDNVQQGQKFELSASVVDAFRGVLLSDSLEPAFIAEMLSLPSHNEVSGWYERVDIDAVASVL
NSMKVTLAAELEDELAAVYHSHALTEYTIDHDSIGKRTLRKVCLSYLAHTEKGNDLVVAMYQQANNMTDTMAAMGAANSA
QLPCRETLMADYSDKWKHDGLVMDKWFALQGSNPSSNALEVIKASMSHQAFSLKNPNRTRNLVGSFLNMNPVQFHAKSGQ
GYAFAGEILRELNSSNPQVASRLIDPLLKFRKYDDERQALIKKELETLKNMDNLAKDLFEKVAKALEA

Sequences:

>Translated_868_residues
MAHTPQAKYRKDYQSPSHTISQIDLTFDLYDSASIITAVSSVKQEKDSSTLVLDGEGLTLVSVLVEGQEWTQFEQSETQL
TLSGLPKDFTLTIVTEVNPEGNSALEGLYKSGGAFCTQCEAEGFRRITYYMDRPDVLAKFTTTVIADKAENPFLLSNGNR
VDEGEAENGRHWVKWQDPHPKPAYLFALVAGDFDVLRDAYTTQSGRKVDLEIFVDKGNLDRANHAMVSLINSMKWDEERF
NLEYDLDIYMIVAVDFFNMGAMENKGLNVFNSKFVLANDQTATDTDYLGIEAVIGHEYFHNWTGNRVTCRDWFQLSLKEG
LTVFRDQEFSSDLGSRAVNRINNVRIIRGPQFAEDASPMSHPIRPEKVIEMNNFYTLTVYEKGSEVIRMIHTLLGEEGFQ
KGMKLYFERHDGTAATCEDFVAAMEDASGVDLSQFRLWYSQSGTPTLSVESHYNAEKKEYTLTTRQVTAPTHEQTDKQAL
HIPLDIELYTASGEVIGLQCNGQPVHNVLDVKEAEQTFVFENVSEQPIPSLLREFSAPVKLEYDYSDEELIFLMVNARNE
FSRWDAGQMLLAKYIRSNVDNVQQGQKFELSASVVDAFRGVLLSDSLEPAFIAEMLSLPSHNEVSGWYERVDIDAVASVL
NSMKVTLAAELEDELAAVYHSHALTEYTIDHDSIGKRTLRKVCLSYLAHTEKGNDLVVAMYQQANNMTDTMAAMGAANSA
QLPCRETLMADYSDKWKHDGLVMDKWFALQGSNPSSNALEVIKASMSHQAFSLKNPNRTRNLVGSFLNMNPVQFHAKSGQ
GYAFAGEILRELNSSNPQVASRLIDPLLKFRKYDDERQALIKKELETLKNMDNLAKDLFEKVAKALEA
>Mature_867_residues
AHTPQAKYRKDYQSPSHTISQIDLTFDLYDSASIITAVSSVKQEKDSSTLVLDGEGLTLVSVLVEGQEWTQFEQSETQLT
LSGLPKDFTLTIVTEVNPEGNSALEGLYKSGGAFCTQCEAEGFRRITYYMDRPDVLAKFTTTVIADKAENPFLLSNGNRV
DEGEAENGRHWVKWQDPHPKPAYLFALVAGDFDVLRDAYTTQSGRKVDLEIFVDKGNLDRANHAMVSLINSMKWDEERFN
LEYDLDIYMIVAVDFFNMGAMENKGLNVFNSKFVLANDQTATDTDYLGIEAVIGHEYFHNWTGNRVTCRDWFQLSLKEGL
TVFRDQEFSSDLGSRAVNRINNVRIIRGPQFAEDASPMSHPIRPEKVIEMNNFYTLTVYEKGSEVIRMIHTLLGEEGFQK
GMKLYFERHDGTAATCEDFVAAMEDASGVDLSQFRLWYSQSGTPTLSVESHYNAEKKEYTLTTRQVTAPTHEQTDKQALH
IPLDIELYTASGEVIGLQCNGQPVHNVLDVKEAEQTFVFENVSEQPIPSLLREFSAPVKLEYDYSDEELIFLMVNARNEF
SRWDAGQMLLAKYIRSNVDNVQQGQKFELSASVVDAFRGVLLSDSLEPAFIAEMLSLPSHNEVSGWYERVDIDAVASVLN
SMKVTLAAELEDELAAVYHSHALTEYTIDHDSIGKRTLRKVCLSYLAHTEKGNDLVVAMYQQANNMTDTMAAMGAANSAQ
LPCRETLMADYSDKWKHDGLVMDKWFALQGSNPSSNALEVIKASMSHQAFSLKNPNRTRNLVGSFLNMNPVQFHAKSGQG
YAFAGEILRELNSSNPQVASRLIDPLLKFRKYDDERQALIKKELETLKNMDNLAKDLFEKVAKALEA

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=425, Percent_Identity=25.8823529411765, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI132814467, Length=386, Percent_Identity=27.2020725388601, Blast_Score=111, Evalue=4e-24,
Organism=Homo sapiens, GI310133497, Length=364, Percent_Identity=25.8241758241758, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI310123622, Length=364, Percent_Identity=25.8241758241758, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI61742775, Length=381, Percent_Identity=25.4593175853018, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI61742777, Length=381, Percent_Identity=25.4593175853018, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI194306629, Length=346, Percent_Identity=27.1676300578035, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI11641261, Length=346, Percent_Identity=27.1676300578035, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI94818901, Length=254, Percent_Identity=27.5590551181102, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI94818891, Length=254, Percent_Identity=27.5590551181102, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI194239713, Length=414, Percent_Identity=25.3623188405797, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI4505029, Length=486, Percent_Identity=25.3086419753086, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI7019561, Length=320, Percent_Identity=25.3125, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI157266300, Length=374, Percent_Identity=23.7967914438503, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI1787163, Length=869, Percent_Identity=63.9815880322209, Blast_Score=1164, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989076, Length=443, Percent_Identity=25.2821670428894, Blast_Score=126, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71989071, Length=443, Percent_Identity=25.2821670428894, Blast_Score=126, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17569221, Length=389, Percent_Identity=25.706940874036, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115533276, Length=394, Percent_Identity=25.8883248730964, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI115533278, Length=394, Percent_Identity=25.8883248730964, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17569225, Length=358, Percent_Identity=26.536312849162, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133903840, Length=375, Percent_Identity=24.8, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565628, Length=397, Percent_Identity=24.9370277078086, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193206928, Length=387, Percent_Identity=24.5478036175711, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193206926, Length=387, Percent_Identity=24.5478036175711, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71990873, Length=178, Percent_Identity=24.1573033707865, Blast_Score=67, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321837, Length=426, Percent_Identity=27.2300469483568, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI9755335, Length=345, Percent_Identity=27.536231884058, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324283, Length=352, Percent_Identity=21.0227272727273, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655257, Length=378, Percent_Identity=28.8359788359788, Blast_Score=143, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24655252, Length=378, Percent_Identity=28.8359788359788, Blast_Score=143, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24655274, Length=385, Percent_Identity=28.3116883116883, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24655260, Length=385, Percent_Identity=28.3116883116883, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24655265, Length=385, Percent_Identity=28.3116883116883, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24655268, Length=385, Percent_Identity=28.3116883116883, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24646516, Length=371, Percent_Identity=28.8409703504043, Blast_Score=133, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24646518, Length=371, Percent_Identity=28.8409703504043, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24646514, Length=366, Percent_Identity=28.9617486338798, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI221379089, Length=353, Percent_Identity=27.1954674220963, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24651025, Length=403, Percent_Identity=25.5583126550869, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24651023, Length=403, Percent_Identity=25.5583126550869, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24651021, Length=403, Percent_Identity=25.5583126550869, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21358341, Length=466, Percent_Identity=24.0343347639485, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24651016, Length=298, Percent_Identity=27.8523489932886, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24648786, Length=383, Percent_Identity=25.3263707571802, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24650973, Length=398, Percent_Identity=25.8793969849246, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45550850, Length=398, Percent_Identity=25.8793969849246, Blast_Score=90, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24646510, Length=221, Percent_Identity=28.9592760180996, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646512, Length=221, Percent_Identity=28.9592760180996, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI161078673, Length=443, Percent_Identity=23.2505643340858, Blast_Score=83, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28571901, Length=443, Percent_Identity=23.2505643340858, Blast_Score=83, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24648790, Length=218, Percent_Identity=25.6880733944954, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28571792, Length=361, Percent_Identity=23.8227146814404, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 97705; Mature: 97574

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTPQAKYRKDYQSPSHTISQIDLTFDLYDSASIITAVSSVKQEKDSSTLVLDGEGLTL
CCCCCCHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCEE
VSVLVEGQEWTQFEQSETQLTLSGLPKDFTLTIVTEVNPEGNSALEGLYKSGGAFCTQCE
EEEEECCCHHHHHCCCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCEEEECC
AEGFRRITYYMDRPDVLAKFTTTVIADKAENPFLLSNGNRVDEGEAENGRHWVKWQDPHP
CCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCC
KPAYLFALVAGDFDVLRDAYTTQSGRKVDLEIFVDKGNLDRANHAMVSLINSMKWDEERF
CCEEEEEEECCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHC
NLEYDLDIYMIVAVDFFNMGAMENKGLNVFNSKFVLANDQTATDTDYLGIEAVIGHEYFH
CEEECCCEEEEEEEHHHCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCEEEEHHHHHHH
NWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRIIRGPQFAEDASPMS
CCCCCEEEEHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC
HPIRPEKVIEMNNFYTLTVYEKGSEVIRMIHTLLGEEGFQKGMKLYFERHDGTAATCEDF
CCCCCHHEEEECCEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHEEEEECCCCHHHHHHH
VAAMEDASGVDLSQFRLWYSQSGTPTLSVESHYNAEKKEYTLTTRQVTAPTHEQTDKQAL
HHHHHCCCCCCHHHHHEEECCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCEE
HIPLDIELYTASGEVIGLQCNGQPVHNVLDVKEAEQTFVFENVSEQPIPSLLREFSAPVK
EEEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHCCCCEE
LEYDYSDEELIFLMVNARNEFSRWDAGQMLLAKYIRSNVDNVQQGQKFELSASVVDAFRG
EEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHCCCEEEEHHHHHHHHHH
VLLSDSLEPAFIAEMLSLPSHNEVSGWYERVDIDAVASVLNSMKVTLAAELEDELAAVYH
HHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHEEEEEEHHHHHHHHHHH
SHALTEYTIDHDSIGKRTLRKVCLSYLAHTEKGNDLVVAMYQQANNMTDTMAAMGAANSA
HHHHEEEECCCHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCHHHHHHHHCCCCCC
QLPCRETLMADYSDKWKHDGLVMDKWFALQGSNPSSNALEVIKASMSHQAFSLKNPNRTR
CCCHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCHHH
NLVGSFLNMNPVQFHAKSGQGYAFAGEILRELNSSNPQVASRLIDPLLKFRKYDDERQAL
HHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHH
IKKELETLKNMDNLAKDLFEKVAKALEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AHTPQAKYRKDYQSPSHTISQIDLTFDLYDSASIITAVSSVKQEKDSSTLVLDGEGLTL
CCCCCHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCEE
VSVLVEGQEWTQFEQSETQLTLSGLPKDFTLTIVTEVNPEGNSALEGLYKSGGAFCTQCE
EEEEECCCHHHHHCCCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCEEEECC
AEGFRRITYYMDRPDVLAKFTTTVIADKAENPFLLSNGNRVDEGEAENGRHWVKWQDPHP
CCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCC
KPAYLFALVAGDFDVLRDAYTTQSGRKVDLEIFVDKGNLDRANHAMVSLINSMKWDEERF
CCEEEEEEECCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHC
NLEYDLDIYMIVAVDFFNMGAMENKGLNVFNSKFVLANDQTATDTDYLGIEAVIGHEYFH
CEEECCCEEEEEEEHHHCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCEEEEHHHHHHH
NWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRIIRGPQFAEDASPMS
CCCCCEEEEHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC
HPIRPEKVIEMNNFYTLTVYEKGSEVIRMIHTLLGEEGFQKGMKLYFERHDGTAATCEDF
CCCCCHHEEEECCEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHEEEEECCCCHHHHHHH
VAAMEDASGVDLSQFRLWYSQSGTPTLSVESHYNAEKKEYTLTTRQVTAPTHEQTDKQAL
HHHHHCCCCCCHHHHHEEECCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCEE
HIPLDIELYTASGEVIGLQCNGQPVHNVLDVKEAEQTFVFENVSEQPIPSLLREFSAPVK
EEEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHCCCCEE
LEYDYSDEELIFLMVNARNEFSRWDAGQMLLAKYIRSNVDNVQQGQKFELSASVVDAFRG
EEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHCCCEEEEHHHHHHHHHH
VLLSDSLEPAFIAEMLSLPSHNEVSGWYERVDIDAVASVLNSMKVTLAAELEDELAAVYH
HHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHEEEEEEHHHHHHHHHHH
SHALTEYTIDHDSIGKRTLRKVCLSYLAHTEKGNDLVVAMYQQANNMTDTMAAMGAANSA
HHHHEEEECCCHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCHHHHHHHHCCCCCC
QLPCRETLMADYSDKWKHDGLVMDKWFALQGSNPSSNALEVIKASMSHQAFSLKNPNRTR
CCCHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCHHH
NLVGSFLNMNPVQFHAKSGQGYAFAGEILRELNSSNPQVASRLIDPLLKFRKYDDERQAL
HHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHH
IKKELETLKNMDNLAKDLFEKVAKALEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]