Click here to switch to the map view.

The map label for this gene is prc [H]

Identifier: 218709408

GI number: 218709408

Start: 1550874

End: 1552868

Strand: Direct

Name: prc [H]

Synonym: VS_1417

Alternate gene names: 218709408

Gene position: 1550874-1552868 (Clockwise)

Preceding gene: 218709407

Following gene: 218709409

Centisome position: 47.01

GC content: 41.5

Gene sequence:

>1995_bases
ATGAAATGCCGTTCAAAATTGACACTGATTGCTGCTGGCTTTTTGCTAGCAGCTTCAGCTCAGGCTCTTGAAGCCAAATT
AAATCAGGACGATTTACCTCTACTCGCTCCTGAGGTTCAACACGAAACTGCTAGTAAACGTGTTACTTCTCGATTTACTC
GTTCCCACTATAAACACTTCAATCTCAACGATGATTTCTCCCAAGCTATCTTTAATCGTTATTTAGAGATGTTGGATTAT
AACCGTAATATCTTCACTCAAGCTGATATTGATTCTTTCGCTACTTCATCTAAACAAATTGATGATCAACTGAAAGCCGG
TAATAACCAAATTGCATTCGATGTTTATAATTTGTCCATGCAGAAGCGTTTTGAACGTTTCCAATATGCGCTGTCTTTAC
TAGATACTGAGATTAAGTTTGATACTGATGAAAGTATTGAGCTCAATCGTAGCGAAGCGGAATGGCCAAAAGATATCGCT
GAAGTGAATGAGCTTTGGAGGAAGCGTGTTAAATACGACGCGTTGAATCTAAAACTTACAGGTAAAGAGTGGCCAGAGAT
TCAAGAAGTTTTGGAAAAGCGTTACAACAATGCGATGAAGCGTATTACGCAATCGCACAACGAAGATGCTTTCCAGATCT
ACATGAACGCATTCGCGCGAGAAGTTGATCCTCATACCAGTTACCTTTCTCCAAGAAATGCAGAGCAATTCCAGTCTGAG
ATGAATCTATCTCTAGAAGGCATTGGTGCTGTACTTCAAATGACAGACGACTACACCGTTATCCGATCTCTCGTTGCTGG
TGGCCCTGCGTCAAACAGCAAGCAATTGAGTGATGGTGACCGTATTGTTGGTGTTGGTCAAGATGGCGAAGATATTGTTG
ATGTTATCGGCTGGCGTTTAGACGATGTAGTGCAATTAATTAAAGGACCGAAAGGGACTAAAGTTAAGCTACAGATCTTG
CCAGATGGTAAAGATGCAAAAAGTCACGTTGTCACAATTGTACGCGATAAGATTCGCTTAGAAGACCGCGCTGTTAAATC
AGAAGTTATCGAGAAAGATGGCAAGAAGATTGGCGTACTCGAAGTACCAAGCTTCTATGTTGGCCTTTCTAAAGATACTG
ATAAACTGATCACCGAACTTAAAGAGCAAGGTGTCGAAGGTATCATTGTTGATCTGCGAAACAACGGTGGTGGTGCACTA
ACGGAAGCAACCGAACTCTCTGGTTTGTTTATCAAAGAGGGGCCCGTTGTTCAAGTTCGTGATAGCTACGGTCGTGTAAA
AGTGAACAGTGATACTGATGGCGAAATTAGTTATCAAGGTCCATTAACGGTATTGGTGAATCGCTACAGTGCTTCAGCAT
CTGAAATCTTTGCAGCAGCGATGCAAGATTATGGTCGTGCAATTATCCTTGGTGAAAACTCTTTCGGTAAAGGAACGGTG
CAACAACACCGCTCTTTGAATCATATTTATGATTTGTTCGATAAAGAGTTAGGCTACGTTCAATACACCATCCAGAAATT
CTACCGAATCAATGGCGGAAGCACGCAAAACAAAGGTGTAGTGCCTGATATTGCTTACCCAACGGCAATTGATCCAGCAG
ATACTGGTGAAAGTGTTGAAGATAATGCTCTACCTTGGGATAGCATAGATAAAGCTAACTATTCAGTGTTACAGCGTAAC
GATGAGCAAGTTGCTGCTTTAACCGCTCAACACCAAGCTCGTATTGCGACAGACATGGAGTTTGGCTTTATCGCGCAAGA
TATTGAAAAATATAAGGCTGATAAAGATGATAATGACCTTTCTTTGAACGAAAAAGTACGTCAACAAGAGAGTGATGATG
GGGATGTGCTTCGTCTAGAGCGTATCAATCAACGTCAAAAAGCCGCTAAGTTAGAGGCATTTAAAACGTTGGATGATATC
CCTAAAGACTACGAAGCCCCAGATGCTTATCTTGATGAGTCAGTCGCTATCATGCTGGATATGATAAAGAAATAG

Upstream 100 bases:

>100_bases
TTGAAATCAATAAGGAAGATGTGCGTGTTCAGTTAGCAAACGGCCTACAAATGGTTGTTAAAGCGGAGCACTTGCGCGCT
TAAAGGAGATACTCCTACGC

Downstream 100 bases:

>100_bases
ACGCTAACGTGCCTTGTTAAAGGCAGCGTTTTTTAAGAAAGCGAGCTTAGGCTCGCTTTTTTTGTGTCTATGATTTGACA
GGAATACCTGATTGTAACCG

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MKCRSKLTLIAAGFLLAASAQALEAKLNQDDLPLLAPEVQHETASKRVTSRFTRSHYKHFNLNDDFSQAIFNRYLEMLDY
NRNIFTQADIDSFATSSKQIDDQLKAGNNQIAFDVYNLSMQKRFERFQYALSLLDTEIKFDTDESIELNRSEAEWPKDIA
EVNELWRKRVKYDALNLKLTGKEWPEIQEVLEKRYNNAMKRITQSHNEDAFQIYMNAFAREVDPHTSYLSPRNAEQFQSE
MNLSLEGIGAVLQMTDDYTVIRSLVAGGPASNSKQLSDGDRIVGVGQDGEDIVDVIGWRLDDVVQLIKGPKGTKVKLQIL
PDGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKDGKKIGVLEVPSFYVGLSKDTDKLITELKEQGVEGIIVDLRNNGGGAL
TEATELSGLFIKEGPVVQVRDSYGRVKVNSDTDGEISYQGPLTVLVNRYSASASEIFAAAMQDYGRAIILGENSFGKGTV
QQHRSLNHIYDLFDKELGYVQYTIQKFYRINGGSTQNKGVVPDIAYPTAIDPADTGESVEDNALPWDSIDKANYSVLQRN
DEQVAALTAQHQARIATDMEFGFIAQDIEKYKADKDDNDLSLNEKVRQQESDDGDVLRLERINQRQKAAKLEAFKTLDDI
PKDYEAPDAYLDESVAIMLDMIKK

Sequences:

>Translated_664_residues
MKCRSKLTLIAAGFLLAASAQALEAKLNQDDLPLLAPEVQHETASKRVTSRFTRSHYKHFNLNDDFSQAIFNRYLEMLDY
NRNIFTQADIDSFATSSKQIDDQLKAGNNQIAFDVYNLSMQKRFERFQYALSLLDTEIKFDTDESIELNRSEAEWPKDIA
EVNELWRKRVKYDALNLKLTGKEWPEIQEVLEKRYNNAMKRITQSHNEDAFQIYMNAFAREVDPHTSYLSPRNAEQFQSE
MNLSLEGIGAVLQMTDDYTVIRSLVAGGPASNSKQLSDGDRIVGVGQDGEDIVDVIGWRLDDVVQLIKGPKGTKVKLQIL
PDGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKDGKKIGVLEVPSFYVGLSKDTDKLITELKEQGVEGIIVDLRNNGGGAL
TEATELSGLFIKEGPVVQVRDSYGRVKVNSDTDGEISYQGPLTVLVNRYSASASEIFAAAMQDYGRAIILGENSFGKGTV
QQHRSLNHIYDLFDKELGYVQYTIQKFYRINGGSTQNKGVVPDIAYPTAIDPADTGESVEDNALPWDSIDKANYSVLQRN
DEQVAALTAQHQARIATDMEFGFIAQDIEKYKADKDDNDLSLNEKVRQQESDDGDVLRLERINQRQKAAKLEAFKTLDDI
PKDYEAPDAYLDESVAIMLDMIKK
>Mature_664_residues
MKCRSKLTLIAAGFLLAASAQALEAKLNQDDLPLLAPEVQHETASKRVTSRFTRSHYKHFNLNDDFSQAIFNRYLEMLDY
NRNIFTQADIDSFATSSKQIDDQLKAGNNQIAFDVYNLSMQKRFERFQYALSLLDTEIKFDTDESIELNRSEAEWPKDIA
EVNELWRKRVKYDALNLKLTGKEWPEIQEVLEKRYNNAMKRITQSHNEDAFQIYMNAFAREVDPHTSYLSPRNAEQFQSE
MNLSLEGIGAVLQMTDDYTVIRSLVAGGPASNSKQLSDGDRIVGVGQDGEDIVDVIGWRLDDVVQLIKGPKGTKVKLQIL
PDGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKDGKKIGVLEVPSFYVGLSKDTDKLITELKEQGVEGIIVDLRNNGGGAL
TEATELSGLFIKEGPVVQVRDSYGRVKVNSDTDGEISYQGPLTVLVNRYSASASEIFAAAMQDYGRAIILGENSFGKGTV
QQHRSLNHIYDLFDKELGYVQYTIQKFYRINGGSTQNKGVVPDIAYPTAIDPADTGESVEDNALPWDSIDKANYSVLQRN
DEQVAALTAQHQARIATDMEFGFIAQDIEKYKADKDDNDLSLNEKVRQQESDDGDVLRLERINQRQKAAKLEAFKTLDDI
PKDYEAPDAYLDESVAIMLDMIKK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=668, Percent_Identity=55.8383233532934, Blast_Score=759, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 74751; Mature: 74751

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCRSKLTLIAAGFLLAASAQALEAKLNQDDLPLLAPEVQHETASKRVTSRFTRSHYKHF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
NLNDDFSQAIFNRYLEMLDYNRNIFTQADIDSFATSSKQIDDQLKAGNNQIAFDVYNLSM
CCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCHHHHHHHHHCCCCEEEEEEECCHH
QKRFERFQYALSLLDTEIKFDTDESIELNRSEAEWPKDIAEVNELWRKRVKYDALNLKLT
HHHHHHHHHHHHHHHHHEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCEEEEEEC
GKEWPEIQEVLEKRYNNAMKRITQSHNEDAFQIYMNAFAREVDPHTSYLSPRNAEQFQSE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
MNLSLEGIGAVLQMTDDYTVIRSLVAGGPASNSKQLSDGDRIVGVGQDGEDIVDVIGWRL
HCCCHHHCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCH
DDVVQLIKGPKGTKVKLQILPDGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKDGKKIGVL
HHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
EVPSFYVGLSKDTDKLITELKEQGVEGIIVDLRNNGGGALTEATELSGLFIKEGPVVQVR
ECCCEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHCCCEEEECCCEEEEE
DSYGRVKVNSDTDGEISYQGPLTVLVNRYSASASEIFAAAMQDYGRAIILGENSFGKGTV
CCCCEEEECCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHH
QQHRSLNHIYDLFDKELGYVQYTIQKFYRINGGSTQNKGVVPDIAYPTAIDPADTGESVE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DNALPWDSIDKANYSVLQRNDEQVAALTAQHQARIATDMEFGFIAQDIEKYKADKDDNDL
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
SLNEKVRQQESDDGDVLRLERINQRQKAAKLEAFKTLDDIPKDYEAPDAYLDESVAIMLD
CHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
MIKK
HHCC
>Mature Secondary Structure
MKCRSKLTLIAAGFLLAASAQALEAKLNQDDLPLLAPEVQHETASKRVTSRFTRSHYKHF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
NLNDDFSQAIFNRYLEMLDYNRNIFTQADIDSFATSSKQIDDQLKAGNNQIAFDVYNLSM
CCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCHHHHHHHHHCCCCEEEEEEECCHH
QKRFERFQYALSLLDTEIKFDTDESIELNRSEAEWPKDIAEVNELWRKRVKYDALNLKLT
HHHHHHHHHHHHHHHHHEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCEEEEEEC
GKEWPEIQEVLEKRYNNAMKRITQSHNEDAFQIYMNAFAREVDPHTSYLSPRNAEQFQSE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
MNLSLEGIGAVLQMTDDYTVIRSLVAGGPASNSKQLSDGDRIVGVGQDGEDIVDVIGWRL
HCCCHHHCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCH
DDVVQLIKGPKGTKVKLQILPDGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKDGKKIGVL
HHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
EVPSFYVGLSKDTDKLITELKEQGVEGIIVDLRNNGGGALTEATELSGLFIKEGPVVQVR
ECCCEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHCCCEEEECCCEEEEE
DSYGRVKVNSDTDGEISYQGPLTVLVNRYSASASEIFAAAMQDYGRAIILGENSFGKGTV
CCCCEEEECCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHH
QQHRSLNHIYDLFDKELGYVQYTIQKFYRINGGSTQNKGVVPDIAYPTAIDPADTGESVE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DNALPWDSIDKANYSVLQRNDEQVAALTAQHQARIATDMEFGFIAQDIEKYKADKDDNDL
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
SLNEKVRQQESDDGDVLRLERINQRQKAAKLEAFKTLDDIPKDYEAPDAYLDESVAIMLD
CHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
MIKK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]