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The map label for this gene is 218709227

Identifier: 218709227

GI number: 218709227

Start: 1308301

End: 1309539

Strand: Reverse

Name: 218709227

Synonym: VS_1234

Alternate gene names: NA

Gene position: 1309539-1308301 (Counterclockwise)

Preceding gene: 218709228

Following gene: 218709220

Centisome position: 39.69

GC content: 44.31

Gene sequence:

>1239_bases
TTGCATACTCTAGAACAACTTAAATCAGGGCAACTTAAAGGGATTAAGCACTTAAAACTGTCAGCAGAGCTCACTGAATT
TCCATTAGAGATCTTAGATCTTGCCGATTCTCTAGAGGTTCTAGACCTTTATGGAAACCAACTATCAAGCTTACCAGACG
AGCTATCACAGCTGACTAACCTGCGTATCATCTTCGCGTCGAATAACCTGTTCACGCACCTTCCTGATGTTCTAGGTACT
CTTCCTAAGCTCGAAATGGTTGGCTTCAAATCTAATCAAATTAAAACCGTCAGCGAGCAATCTTTACCTGCTCAATTACG
TTGGTTGATCCTGACAGACAATGCAATCGAGGTTCTCCCTCACTCACTAGGTGAAAGACCACGCCTGCAAAAGCTCGCAT
TGGCAGGTAACAAGATTCGTGTTTTACCAGAAAGTATGGAAAAGCTATCAAACCTTGAACTGGTTCGTCTGTCTGCAAAC
CAACTGACTGAATTCCCAGAGTTCCTTATCAAGCTACCAAAACTGGCTTGGTTAGCGTTTGCGGGTAACCCATTTTGCAA
ACATCCAAGCAGCTTAGATAGCGTGCCTGCCGTCAGCTCGCAATGCTACTCACTCAATCAAGTGCTGGGCCAAGGTGCGT
CTGGTGTAATTTCTCATGCTAACTGGTTAAACGGTGACTTTGATTTCCCACAAGAAGTGGCGGTTAAAGTATTCAAAGGC
GAAGTGACCAGTGACGGTTACCCACATGATGAACTTGAAGCATGTCTTCAAGCAGGCCAACATAGCAACCTAGTGAAGTC
TATCGCACAAGTTGATGAAGAGAACTACCTAGCATTGGTGATGGAGCTTATCCCGAGCAACTACTACAACCTAGGTTTGC
CCCCTACTCTTGAAAGCTGCACTCGCGATACGTTCAACGAAGGCTTCGAGCTTTCAATTGCTAAGATCAATAGTATTACA
GAGCAGATGATTGATGTGTTTGAACACCTTCATGCCAACAAAGTTTGTCATGGTGATCTATACGCACACAACACTTTGGT
TAACGAGCAAGGTCAGATGATCTTTGGTGACTTCGGAGCAGCAACTATCTACGGTTATCTGACTGAAGAGCAGCAACAAG
GCATTCGACAAATCGAAGCGCGTGCACTGAAGTACTTTATTGAAGACCTATTGACGGTATGTACAAAGCAAGACCAAGAC
AGCAAGCTTTATACTCGATTGGCGAACTTCGAAGCTTAA

Upstream 100 bases:

>100_bases
TTCACTTAGTGTAGTTAAGCGAGCATCGCTCCGGTGCTCGCCTTTCTCGATTGAGACAAGTAAACTACACGCCTCGAACA
TCTATTCATAAGGCTAAGGT

Downstream 100 bases:

>100_bases
TAACCTAAACTACTCAGTCGAATTGAAAACAACAAAGCCAACATCACTGTTGGCTTTGTTATTCTTGGAACATCACTTAT
TTTAATGGACAAGCAAGGTC

Product: hypothetical protein

Products: NA

Alternate protein names: Leucine-Rich Repeat-Containing Protein; Protein Kinase; Cytoplasmic Membrane Protein; Leucine-Rich Repeat Protein; Leucine-Rich Repeat-Containing Protein Kinase; Ras Family; Miro-Like Protein; Leucine Rich Repeat Domain-Containing Protein; Kinase; Phosphoprotein Phosphatase; Leucine-Rich Repeat Containing Protein; Serine/Threonine-Protein Kinase-Like Domain Protein; Miro Domain Protein; Miro Domain-Containing Protein; Serine/Threonine-Protein Kinase-Like Domain; Leucine-Rich RepeAt And Death Domain-Containing Protein; Protein Kinase Domain-Containing Protein; Leucine Rich Repeat Domain Protein; Outermembrane Protein; Protein KinaseLeucine-Rich Repeat Protein; Lipoprotein

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MHTLEQLKSGQLKGIKHLKLSAELTEFPLEILDLADSLEVLDLYGNQLSSLPDELSQLTNLRIIFASNNLFTHLPDVLGT
LPKLEMVGFKSNQIKTVSEQSLPAQLRWLILTDNAIEVLPHSLGERPRLQKLALAGNKIRVLPESMEKLSNLELVRLSAN
QLTEFPEFLIKLPKLAWLAFAGNPFCKHPSSLDSVPAVSSQCYSLNQVLGQGASGVISHANWLNGDFDFPQEVAVKVFKG
EVTSDGYPHDELEACLQAGQHSNLVKSIAQVDEENYLALVMELIPSNYYNLGLPPTLESCTRDTFNEGFELSIAKINSIT
EQMIDVFEHLHANKVCHGDLYAHNTLVNEQGQMIFGDFGAATIYGYLTEEQQQGIRQIEARALKYFIEDLLTVCTKQDQD
SKLYTRLANFEA

Sequences:

>Translated_412_residues
MHTLEQLKSGQLKGIKHLKLSAELTEFPLEILDLADSLEVLDLYGNQLSSLPDELSQLTNLRIIFASNNLFTHLPDVLGT
LPKLEMVGFKSNQIKTVSEQSLPAQLRWLILTDNAIEVLPHSLGERPRLQKLALAGNKIRVLPESMEKLSNLELVRLSAN
QLTEFPEFLIKLPKLAWLAFAGNPFCKHPSSLDSVPAVSSQCYSLNQVLGQGASGVISHANWLNGDFDFPQEVAVKVFKG
EVTSDGYPHDELEACLQAGQHSNLVKSIAQVDEENYLALVMELIPSNYYNLGLPPTLESCTRDTFNEGFELSIAKINSIT
EQMIDVFEHLHANKVCHGDLYAHNTLVNEQGQMIFGDFGAATIYGYLTEEQQQGIRQIEARALKYFIEDLLTVCTKQDQD
SKLYTRLANFEA
>Mature_412_residues
MHTLEQLKSGQLKGIKHLKLSAELTEFPLEILDLADSLEVLDLYGNQLSSLPDELSQLTNLRIIFASNNLFTHLPDVLGT
LPKLEMVGFKSNQIKTVSEQSLPAQLRWLILTDNAIEVLPHSLGERPRLQKLALAGNKIRVLPESMEKLSNLELVRLSAN
QLTEFPEFLIKLPKLAWLAFAGNPFCKHPSSLDSVPAVSSQCYSLNQVLGQGASGVISHANWLNGDFDFPQEVAVKVFKG
EVTSDGYPHDELEACLQAGQHSNLVKSIAQVDEENYLALVMELIPSNYYNLGLPPTLESCTRDTFNEGFELSIAKINSIT
EQMIDVFEHLHANKVCHGDLYAHNTLVNEQGQMIFGDFGAATIYGYLTEEQQQGIRQIEARALKYFIEDLLTVCTKQDQD
SKLYTRLANFEA

Specific function: Unknown

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI63003903, Length=207, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI238908508, Length=186, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI6912638, Length=178, Percent_Identity=34.8314606741573, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI95113664, Length=188, Percent_Identity=32.9787234042553, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI34577083, Length=161, Percent_Identity=34.1614906832298, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI122937315, Length=217, Percent_Identity=29.4930875576037, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI110825984, Length=204, Percent_Identity=28.4313725490196, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI299758423, Length=166, Percent_Identity=30.7228915662651, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI8923909, Length=170, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI33285015, Length=164, Percent_Identity=33.5365853658537, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI53729363, Length=166, Percent_Identity=30.7228915662651, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI53729359, Length=166, Percent_Identity=30.7228915662651, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI53729361, Length=166, Percent_Identity=30.7228915662651, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI55770895, Length=170, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI41281398, Length=184, Percent_Identity=32.0652173913043, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI157694513, Length=190, Percent_Identity=32.1052631578947, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI153792305, Length=171, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI16904383, Length=192, Percent_Identity=32.2916666666667, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI194394161, Length=179, Percent_Identity=31.2849162011173, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI65301141, Length=244, Percent_Identity=28.2786885245902, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI197333706, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI34222199, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI62912472, Length=176, Percent_Identity=33.5227272727273, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI62912470, Length=176, Percent_Identity=33.5227272727273, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17552452, Length=221, Percent_Identity=32.579185520362, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17550406, Length=163, Percent_Identity=31.9018404907975, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71981160, Length=173, Percent_Identity=33.5260115606936, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71981152, Length=173, Percent_Identity=33.5260115606936, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71991531, Length=184, Percent_Identity=33.1521739130435, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71991525, Length=184, Percent_Identity=33.1521739130435, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71998904, Length=177, Percent_Identity=29.3785310734463, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71993778, Length=174, Percent_Identity=28.735632183908, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71998900, Length=177, Percent_Identity=29.3785310734463, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71993783, Length=175, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17537883, Length=152, Percent_Identity=32.8947368421053, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221379725, Length=173, Percent_Identity=35.2601156069364, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221379722, Length=173, Percent_Identity=35.2601156069364, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62472958, Length=162, Percent_Identity=34.5679012345679, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650334, Length=162, Percent_Identity=34.5679012345679, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650332, Length=162, Percent_Identity=34.5679012345679, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007092, Length=162, Percent_Identity=34.5679012345679, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650336, Length=162, Percent_Identity=34.5679012345679, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362653, Length=162, Percent_Identity=34.5679012345679, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650330, Length=162, Percent_Identity=34.5679012345679, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362651, Length=162, Percent_Identity=34.5679012345679, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18858105, Length=163, Percent_Identity=31.9018404907975, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362657, Length=162, Percent_Identity=34.5679012345679, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362655, Length=162, Percent_Identity=34.5679012345679, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922294, Length=186, Percent_Identity=27.9569892473118, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19922706, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45985; Mature: 45985

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLEQLKSGQLKGIKHLKLSAELTEFPLEILDLADSLEVLDLYGNQLSSLPDELSQLTN
CCCHHHHHCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LRIIFASNNLFTHLPDVLGTLPKLEMVGFKSNQIKTVSEQSLPAQLRWLILTDNAIEVLP
EEEEEECCCHHHHHHHHHHCCCCCEEECCCCCCEEECHHCCCCCEEEEEEEECCHHHHHH
HSLGERPRLQKLALAGNKIRVLPESMEKLSNLELVRLSANQLTEFPEFLIKLPKLAWLAF
HHCCCCCCHHHHHHCCCEEEECHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHEEEE
AGNPFCKHPSSLDSVPAVSSQCYSLNQVLGQGASGVISHANWLNGDFDFPQEVAVKVFKG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCC
EVTSDGYPHDELEACLQAGQHSNLVKSIAQVDEENYLALVMELIPSNYYNLGLPPTLESC
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHH
TRDTFNEGFELSIAKINSITEQMIDVFEHLHANKVCHGDLYAHNTLVNEQGQMIFGDFGA
HHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCEECCCCCEEEECCCH
ATIYGYLTEEQQQGIRQIEARALKYFIEDLLTVCTKQDQDSKLYTRLANFEA
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MHTLEQLKSGQLKGIKHLKLSAELTEFPLEILDLADSLEVLDLYGNQLSSLPDELSQLTN
CCCHHHHHCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LRIIFASNNLFTHLPDVLGTLPKLEMVGFKSNQIKTVSEQSLPAQLRWLILTDNAIEVLP
EEEEEECCCHHHHHHHHHHCCCCCEEECCCCCCEEECHHCCCCCEEEEEEEECCHHHHHH
HSLGERPRLQKLALAGNKIRVLPESMEKLSNLELVRLSANQLTEFPEFLIKLPKLAWLAF
HHCCCCCCHHHHHHCCCEEEECHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHEEEE
AGNPFCKHPSSLDSVPAVSSQCYSLNQVLGQGASGVISHANWLNGDFDFPQEVAVKVFKG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCC
EVTSDGYPHDELEACLQAGQHSNLVKSIAQVDEENYLALVMELIPSNYYNLGLPPTLESC
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHH
TRDTFNEGFELSIAKINSITEQMIDVFEHLHANKVCHGDLYAHNTLVNEQGQMIFGDFGA
HHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCEECCCCCEEEECCCH
ATIYGYLTEEQQQGIRQIEARALKYFIEDLLTVCTKQDQDSKLYTRLANFEA
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA