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The map label for this gene is purC

Identifier: 218709198

GI number: 218709198

Start: 1279120

End: 1280223

Strand: Reverse

Name: purC

Synonym: VS_1205

Alternate gene names: 218709198

Gene position: 1280223-1279120 (Counterclockwise)

Preceding gene: 218709199

Following gene: 218709195

Centisome position: 38.8

GC content: 44.38

Gene sequence:

>1104_bases
ATGAGCCTTGCTGATCAAGTTCTTGCCGTAAATGATGACCTACCAATTCGTACTGATAAACCTGTCCACAGTGGCAAGGT
TCGCTCAGTCTACTGGTTAACTGAAGAAGATAGCCAACGACTAATTAAAGAGAAAGGCTACGATGTAGCACCAGATGCGC
CTTTAGCAATCATGGTGATCAGTGACCGTATCTCTGCATTTGATTGTATCTGGCGTGGTGAAGGGAATCTAAAAGGTGTT
CCAGGTAAAGGAGCGGCTCTGAATGCTATCTCTAACCACTGGTTCAAATTGTTTAAAGACAACGGCCTCGCTGACAGTCA
TATTCTTGATATCCCTCACCCGTTCGTATGGATTGTACAAAAAGCTCGCCCAGTCATGATCGAAGCGATTTGTCGTCAAT
ACATCACAGGTTCAATGTGGCGTGCATACGCAAACGGCGAACGCGAATTCTGTGGTATCGAGATGCCAGAAGGCCTTGAG
AAAGACAAGAAATTGCCTGAGCTACTGATCACACCTTCTACAAAAGGGATTTTGAAAGGTATTCCTGGCGTTCCAGAAGC
TGATGATGTGAACATCACACGTAACAACATCGAAGATAACTTCGCAGCGTTCAACTTTACTCAAGCAAGTGACATTGCGC
ATTACGAGAAACTTCTAAAAGAAGGCTTCAACGTAATTAGCCAAGCACTAGCAAACGTCGACCAAACCTTTGTCGATACC
AAGTTTGAGTTTGGCTACGTCAACGATGCTCAAGGTAAAGAAAAGCTGATCTACATGGACGAAGTGGGTACTCCAGATTC
ATCTCGCATTTGGGATACTCAGGAATACAACAAAGGTAATATCGTTGAAAACTCTAAAGAGGGTTTCCGTCAGTTCTTGC
TTAACTACTTCCCTGATGCAGACATTCTTTTGAACAAAGAACGCATGCCAGAACGTGAAGCATTAGCTCGTGACAATGAG
CTGCCTCTCGATTCACTGATGTCTCTGTCGCGTACTTATCTTGATATCGCAGCGAAAATCACAGGTGCAGAGATCGTACT
GAGCGAGAATCCTAAGCAAGAAATCATCGATGTACTGCGTGCTGACTACGGCCTAATCGATTAA

Upstream 100 bases:

>100_bases
TTTCTCTGGAAGCAAATAGTAGATTGGGTATAATGCCCGTCTAATCATGTGCACACCGCACTTCTCTGTATGACGTTTGA
TAAAAGATAGGAATGTCTAA

Downstream 100 bases:

>100_bases
TAGCGGTTAGATATCAGGTTCTGCCTAAGTACAAAGAACGACTTAAATACAAAAAGGGCCTCATTATTGAGGCCCTTTTT
ACATGTATTTTTTAATCTTA

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSLADQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSQRLIKEKGYDVAPDAPLAIMVISDRISAFDCIWRGEGNLKGV
PGKGAALNAISNHWFKLFKDNGLADSHILDIPHPFVWIVQKARPVMIEAICRQYITGSMWRAYANGEREFCGIEMPEGLE
KDKKLPELLITPSTKGILKGIPGVPEADDVNITRNNIEDNFAAFNFTQASDIAHYEKLLKEGFNVISQALANVDQTFVDT
KFEFGYVNDAQGKEKLIYMDEVGTPDSSRIWDTQEYNKGNIVENSKEGFRQFLLNYFPDADILLNKERMPEREALARDNE
LPLDSLMSLSRTYLDIAAKITGAEIVLSENPKQEIIDVLRADYGLID

Sequences:

>Translated_367_residues
MSLADQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSQRLIKEKGYDVAPDAPLAIMVISDRISAFDCIWRGEGNLKGV
PGKGAALNAISNHWFKLFKDNGLADSHILDIPHPFVWIVQKARPVMIEAICRQYITGSMWRAYANGEREFCGIEMPEGLE
KDKKLPELLITPSTKGILKGIPGVPEADDVNITRNNIEDNFAAFNFTQASDIAHYEKLLKEGFNVISQALANVDQTFVDT
KFEFGYVNDAQGKEKLIYMDEVGTPDSSRIWDTQEYNKGNIVENSKEGFRQFLLNYFPDADILLNKERMPEREALARDNE
LPLDSLMSLSRTYLDIAAKITGAEIVLSENPKQEIIDVLRADYGLID
>Mature_366_residues
SLADQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSQRLIKEKGYDVAPDAPLAIMVISDRISAFDCIWRGEGNLKGVP
GKGAALNAISNHWFKLFKDNGLADSHILDIPHPFVWIVQKARPVMIEAICRQYITGSMWRAYANGEREFCGIEMPEGLEK
DKKLPELLITPSTKGILKGIPGVPEADDVNITRNNIEDNFAAFNFTQASDIAHYEKLLKEGFNVISQALANVDQTFVDTK
FEFGYVNDAQGKEKLIYMDEVGTPDSSRIWDTQEYNKGNIVENSKEGFRQFLLNYFPDADILLNKERMPEREALARDNEL
PLDSLMSLSRTYLDIAAKITGAEIVLSENPKQEIIDVLRADYGLID

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=315, Percent_Identity=27.9365079365079, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PUR7_VIBSL (B7VMT0)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416819.1
- GeneID:   7160790
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_1205
- HOGENOM:   HBG555040
- OMA:   SSRIWDG
- ProtClustDB:   PRK13960
- HAMAP:   MF_00137
- InterPro:   IPR013816
- InterPro:   IPR014106
- InterPro:   IPR001636
- Gene3D:   G3DSA:3.30.470.20
- PANTHER:   PTHR11609
- TIGRFAMs:   TIGR02735

Pfam domain/function: PF01259 SAICAR_synt

EC number: =6.3.2.6

Molecular weight: Translated: 41317; Mature: 41186

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS01057 SAICAR_SYNTHETASE_1; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLADQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSQRLIKEKGYDVAPDAPLAIMVI
CCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEE
SDRISAFDCIWRGEGNLKGVPGKGAALNAISNHWFKLFKDNGLADSHILDIPHPFVWIVQ
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHEEHHH
KARPVMIEAICRQYITGSMWRAYANGEREFCGIEMPEGLEKDKKLPELLITPSTKGILKG
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHCCCCEEECCCCCHHHHC
IPGVPEADDVNITRNNIEDNFAAFNFTQASDIAHYEKLLKEGFNVISQALANVDQTFVDT
CCCCCCCCCCCEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVNDAQGKEKLIYMDEVGTPDSSRIWDTQEYNKGNIVENSKEGFRQFLLNYFPDA
CEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
DILLNKERMPEREALARDNELPLDSLMSLSRTYLDIAAKITGAEIVLSENPKQEIIDVLR
CEEECHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHH
ADYGLID
HHCCCCC
>Mature Secondary Structure 
SLADQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSQRLIKEKGYDVAPDAPLAIMVI
CCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEE
SDRISAFDCIWRGEGNLKGVPGKGAALNAISNHWFKLFKDNGLADSHILDIPHPFVWIVQ
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHEEHHH
KARPVMIEAICRQYITGSMWRAYANGEREFCGIEMPEGLEKDKKLPELLITPSTKGILKG
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHCCCCEEECCCCCHHHHC
IPGVPEADDVNITRNNIEDNFAAFNFTQASDIAHYEKLLKEGFNVISQALANVDQTFVDT
CCCCCCCCCCCEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVNDAQGKEKLIYMDEVGTPDSSRIWDTQEYNKGNIVENSKEGFRQFLLNYFPDA
CEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
DILLNKERMPEREALARDNELPLDSLMSLSRTYLDIAAKITGAEIVLSENPKQEIIDVLR
CEEECHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHH
ADYGLID
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA