Click here to switch to the map view.

The map label for this gene is pabC [H]

Identifier: 218709021

GI number: 218709021

Start: 1067845

End: 1068723

Strand: Direct

Name: pabC [H]

Synonym: VS_1027

Alternate gene names: 218709021

Gene position: 1067845-1068723 (Clockwise)

Preceding gene: 218709020

Following gene: 218709022

Centisome position: 32.37

GC content: 44.71

Gene sequence:

>879_bases
ATGTTTTGGGTTGATGGAGAAAGTCAGCAAACTGTCGATATCTTAGATCGCTCGTTTCAGTATGGAGACGGCTGTTTTAC
TACCATGCTTGTTCAAGATGGCCAGATTCAATATTTTCACGATCATCAGCGTCGTGTTGATGATTGTCTTAAAGCGTTAC
GCATTTCCGAACTTGATTGGAATACGGTTAACCTTTGGCTCGATAATGCACTTGAACATATCCAATACAATGCGCTTCCT
GGTACAAAGAGCCTTGATGGTTCAACGAATCTTCAAGACAAAAACAAGCCTCATAATGAAAAAGCAGGGCTCAAGCTGCA
CGTTAGCCGTGGGGCTGGCGGTCGTGGCTACAGTACCAAGAATATCGCCAAGCCAACGATAACCGTCAGTACATTTGATT
ATCCAAGTCATTATTTCGCGTGGCAAGATTCCGGTGTAGAACTCGGTATCTGCCAACAAGCACTGGGTTTGAGCCCATTA
TTGGCCGGTCATAAGCACAATAATCGCCTTGAGCAAATCTTGATGAAAGATGAAATGGATCAGGCCGGTGAAGTGGATGG
CGTTGTTCTGGATATATCAGGTAACGTGATTGAAACTACCATGGCTAATCTGTTTTGGCGAAAAGGGCAGACGATTCACA
CTCCTCAACTGACGCAAAGTGGCGTTGCTGGGGTTATGCGTAAGCAAGTGTTAACCGCGCTGAATCAAGCTGAACTTTCC
GTTACTATTAGTGACTACTGCTTATCTCAACTCATGCAAGCTGATGAGGTTTTCATGACCAACTCCATTTTAGGGGTTGC
CCCAGTTACCCGTATTAGTGATACCCAATTCAACATTGGAACCGTTACTCGTAGCCTTCAAGGACAACTAAACTCGTGA

Upstream 100 bases:

>100_bases
TCTTATATAAGAGTCAAACATCGTAGATAGTCATAATTAGAACTGTTTTTAAACGGCTCGATGCTTTAGCATTGAGCCGT
TTCTTTTTATGGGGAAAAAC

Downstream 100 bases:

>100_bases
TCAAAAAGTTATTTATTTTTATTATCTTGTGCCTAATCGCAGCCGCGGCTGCTGGTTTTTATGTTTACAACCAAGCGCAA
GATAACCTGAAACAAGTTAT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MFWVDGESQQTVDILDRSFQYGDGCFTTMLVQDGQIQYFHDHQRRVDDCLKALRISELDWNTVNLWLDNALEHIQYNALP
GTKSLDGSTNLQDKNKPHNEKAGLKLHVSRGAGGRGYSTKNIAKPTITVSTFDYPSHYFAWQDSGVELGICQQALGLSPL
LAGHKHNNRLEQILMKDEMDQAGEVDGVVLDISGNVIETTMANLFWRKGQTIHTPQLTQSGVAGVMRKQVLTALNQAELS
VTISDYCLSQLMQADEVFMTNSILGVAPVTRISDTQFNIGTVTRSLQGQLNS

Sequences:

>Translated_292_residues
MFWVDGESQQTVDILDRSFQYGDGCFTTMLVQDGQIQYFHDHQRRVDDCLKALRISELDWNTVNLWLDNALEHIQYNALP
GTKSLDGSTNLQDKNKPHNEKAGLKLHVSRGAGGRGYSTKNIAKPTITVSTFDYPSHYFAWQDSGVELGICQQALGLSPL
LAGHKHNNRLEQILMKDEMDQAGEVDGVVLDISGNVIETTMANLFWRKGQTIHTPQLTQSGVAGVMRKQVLTALNQAELS
VTISDYCLSQLMQADEVFMTNSILGVAPVTRISDTQFNIGTVTRSLQGQLNS
>Mature_292_residues
MFWVDGESQQTVDILDRSFQYGDGCFTTMLVQDGQIQYFHDHQRRVDDCLKALRISELDWNTVNLWLDNALEHIQYNALP
GTKSLDGSTNLQDKNKPHNEKAGLKLHVSRGAGGRGYSTKNIAKPTITVSTFDYPSHYFAWQDSGVELGICQQALGLSPL
LAGHKHNNRLEQILMKDEMDQAGEVDGVVLDISGNVIETTMANLFWRKGQTIHTPQLTQSGVAGVMRKQVLTALNQAELS
VTISDYCLSQLMQADEVFMTNSILGVAPVTRISDTQFNIGTVTRSLQGQLNS

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=286, Percent_Identity=35.3146853146853, Blast_Score=180, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 32447; Mature: 32447

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWVDGESQQTVDILDRSFQYGDGCFTTMLVQDGQIQYFHDHQRRVDDCLKALRISELDW
CEECCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCCC
NTVNLWLDNALEHIQYNALPGTKSLDGSTNLQDKNKPHNEKAGLKLHVSRGAGGRGYSTK
CEEEEEHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
NIAKPTITVSTFDYPSHYFAWQDSGVELGICQQALGLSPLLAGHKHNNRLEQILMKDEMD
CCCCCEEEEEEECCCCCEEEECCCCCEEHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHC
QAGEVDGVVLDISGNVIETTMANLFWRKGQTIHTPQLTQSGVAGVMRKQVLTALNQAELS
CCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEE
VTISDYCLSQLMQADEVFMTNSILGVAPVTRISDTQFNIGTVTRSLQGQLNS
EEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEHHHHHHHHHCCCCC
>Mature Secondary Structure
MFWVDGESQQTVDILDRSFQYGDGCFTTMLVQDGQIQYFHDHQRRVDDCLKALRISELDW
CEECCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCCC
NTVNLWLDNALEHIQYNALPGTKSLDGSTNLQDKNKPHNEKAGLKLHVSRGAGGRGYSTK
CEEEEEHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
NIAKPTITVSTFDYPSHYFAWQDSGVELGICQQALGLSPLLAGHKHNNRLEQILMKDEMD
CCCCCEEEEEEECCCCCEEEECCCCCEEHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHC
QAGEVDGVVLDISGNVIETTMANLFWRKGQTIHTPQLTQSGVAGVMRKQVLTALNQAELS
CCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEE
VTISDYCLSQLMQADEVFMTNSILGVAPVTRISDTQFNIGTVTRSLQGQLNS
EEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]