Click here to switch to the map view.

The map label for this gene is fabH1 [H]

Identifier: 218709016

GI number: 218709016

Start: 1063289

End: 1064239

Strand: Direct

Name: fabH1 [H]

Synonym: VS_1022

Alternate gene names: 218709016

Gene position: 1063289-1064239 (Clockwise)

Preceding gene: 218709015

Following gene: 218709017

Centisome position: 32.23

GC content: 46.9

Gene sequence:

>951_bases
ATGTATAGCAAAATTTTAGGTACTGGCAGCTACTTGCCATCTCAGGTGCGTACTAACGCAGACTTAGAGAAAATGGTAGA
GACTAGCGATGAGTGGATCGTTGCTAGAACAGGTATTAAAGAGCGTCGTATTTCAGCGGAAAACGAAACTGTTGCGGATA
TGGCGTTTTACGCTGCTGAGAATGCCATTGAAATGGCAGGTATCGACAAAGAAGATATTGATTTAATCATCGTTGCGACA
ACCAGCAGTAGCCACACATTTCCGTCTTCGGCATGTCAGGTACAAGGCAAGCTTGGTATCAAAGGCTGCCCTGCGTTTGA
TTTGGCTGCGGCGTGTTCTGGTTTTGTCTACGCACTGTCTGTTGCTGATCAACACATCAAGACTGGCATGTGTAAGAACG
TTTTGGTAATCGGTGCGGATGCACTGTCAAAAACCTGTGATCCGACTGACCGCTCTACTATCATCTTATTTGGTGATGCT
GCAGGTGCGGTGGTTGTTGGCGCAAGCGAAGAGCCAGGTATTTTGTCTACTCACATTTACTCTGATGGTAAATATGGTGA
GCTTCTAAGCCTAGAAGTTCCAGAGCGTGGCGGTGCTGCGGACAAATGGTTGCACATGGCGGGCAACGAAGTATTTAAAG
TGGCGGTAACTCAGCTTTCTAAGCTAGTGAAAGACACATTAGCGGCGAACAATATGGATAAGTCAGAGCTTGATTGGTTA
GTTCCACATCAAGCGAACTACCGTATTATCTCGGCAACCGCTAAAAAGCTGACGATGTCGCTTGATCAAGTTGTGATTAC
TCTTGATAAGCACGGCAATACGTCGGCAGCTACCGTACCAACGGCCCTTGATGAGGCTGTTCGCGACGGGCGAATTAAAC
GTGGTCAAACGCTTCTACTTGAAGCGTTTGGTGGCGGCTTCACTTGGGGTTCTGCGTTAGTTAAATTCTAA

Upstream 100 bases:

>100_bases
ACGCGATTGGTGAGGCAGTACACGAGGTCAAACGACAAGTCCCCAGTCGCATTAGCGATCGTTTGGAAGCGGTTTTACTC
GAGAGGCATTATTAGTCTTC

Downstream 100 bases:

>100_bases
CCCCAAGCGATAATCAACAAACAAGGCACATAACTTATGTGCCTTATTCAATTTTTTGCTTTGCTTAAAGGAAAATTACT
ATGAGCAAATTTGCTATCGT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 1; Beta-ketoacyl-ACP synthase III 1; KAS III 1 [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MYSKILGTGSYLPSQVRTNADLEKMVETSDEWIVARTGIKERRISAENETVADMAFYAAENAIEMAGIDKEDIDLIIVAT
TSSSHTFPSSACQVQGKLGIKGCPAFDLAAACSGFVYALSVADQHIKTGMCKNVLVIGADALSKTCDPTDRSTIILFGDA
AGAVVVGASEEPGILSTHIYSDGKYGELLSLEVPERGGAADKWLHMAGNEVFKVAVTQLSKLVKDTLAANNMDKSELDWL
VPHQANYRIISATAKKLTMSLDQVVITLDKHGNTSAATVPTALDEAVRDGRIKRGQTLLLEAFGGGFTWGSALVKF

Sequences:

>Translated_316_residues
MYSKILGTGSYLPSQVRTNADLEKMVETSDEWIVARTGIKERRISAENETVADMAFYAAENAIEMAGIDKEDIDLIIVAT
TSSSHTFPSSACQVQGKLGIKGCPAFDLAAACSGFVYALSVADQHIKTGMCKNVLVIGADALSKTCDPTDRSTIILFGDA
AGAVVVGASEEPGILSTHIYSDGKYGELLSLEVPERGGAADKWLHMAGNEVFKVAVTQLSKLVKDTLAANNMDKSELDWL
VPHQANYRIISATAKKLTMSLDQVVITLDKHGNTSAATVPTALDEAVRDGRIKRGQTLLLEAFGGGFTWGSALVKF
>Mature_316_residues
MYSKILGTGSYLPSQVRTNADLEKMVETSDEWIVARTGIKERRISAENETVADMAFYAAENAIEMAGIDKEDIDLIIVAT
TSSSHTFPSSACQVQGKLGIKGCPAFDLAAACSGFVYALSVADQHIKTGMCKNVLVIGADALSKTCDPTDRSTIILFGDA
AGAVVVGASEEPGILSTHIYSDGKYGELLSLEVPERGGAADKWLHMAGNEVFKVAVTQLSKLVKDTLAANNMDKSELDWL
VPHQANYRIISATAKKLTMSLDQVVITLDKHGNTSAATVPTALDEAVRDGRIKRGQTLLLEAFGGGFTWGSALVKF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=317, Percent_Identity=72.2397476340694, Blast_Score=485, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 33724; Mature: 33724

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSKILGTGSYLPSQVRTNADLEKMVETSDEWIVARTGIKERRISAENETVADMAFYAAE
CCCCEECCCCCCCHHHHCCCHHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHC
NAIEMAGIDKEDIDLIIVATTSSSHTFPSSACQVQGKLGIKGCPAFDLAAACSGFVYALS
CCCEECCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEEH
VADQHIKTGMCKNVLVIGADALSKTCDPTDRSTIILFGDAAGAVVVGASEEPGILSTHIY
HHHHHHHHCCCCCEEEEECHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
SDGKYGELLSLEVPERGGAADKWLHMAGNEVFKVAVTQLSKLVKDTLAANNMDKSELDWL
CCCCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEE
VPHQANYRIISATAKKLTMSLDQVVITLDKHGNTSAATVPTALDEAVRDGRIKRGQTLLL
CCCCCCCEEEEEHHHHHHHEECEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEE
EAFGGGFTWGSALVKF
EECCCCCCHHHHHHCC
>Mature Secondary Structure
MYSKILGTGSYLPSQVRTNADLEKMVETSDEWIVARTGIKERRISAENETVADMAFYAAE
CCCCEECCCCCCCHHHHCCCHHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHC
NAIEMAGIDKEDIDLIIVATTSSSHTFPSSACQVQGKLGIKGCPAFDLAAACSGFVYALS
CCCEECCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEEH
VADQHIKTGMCKNVLVIGADALSKTCDPTDRSTIILFGDAAGAVVVGASEEPGILSTHIY
HHHHHHHHCCCCCEEEEECHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
SDGKYGELLSLEVPERGGAADKWLHMAGNEVFKVAVTQLSKLVKDTLAANNMDKSELDWL
CCCCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEE
VPHQANYRIISATAKKLTMSLDQVVITLDKHGNTSAATVPTALDEAVRDGRIKRGQTLLL
CCCCCCCEEEEEHHHHHHHEECEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEE
EAFGGGFTWGSALVKF
EECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]