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The map label for this gene is btuR [H]

Identifier: 218709007

GI number: 218709007

Start: 1052774

End: 1053442

Strand: Reverse

Name: btuR [H]

Synonym: VS_1013

Alternate gene names: 218709007

Gene position: 1053442-1052774 (Counterclockwise)

Preceding gene: 218709009

Following gene: 218709003

Centisome position: 31.93

GC content: 44.69

Gene sequence:

>669_bases
ATGGTTTTTGCTATCGTTAAGTTAGGCTATGATAGGCGTAATCACAACTTAAAAGGATTTGTTATGTCGACCGAAGACAA
CAAAGAACAACGCCACAAAGCAAGACAACAGAAAGTAAAAGAGCAAGTCGATGCACGTGTTGCAGCAGCGCAAGAAGTGA
AAGGACTGTTATTGGTTATTACTGGCAACGGGAAAGGGAAATCGACATCAGGTTTCGGTACGATTACACGTGCAGTCGGT
CACGGTAAGAAATGTGCCGTTGCTCAGTTTGTAAAGGGAACCTGGGATAACGGTGAAAAGAACGTTCTTCAAAAACTCGA
TGTAGAGTTCCAAGTGATGGGTACAGGCTTTACTTGGGAAACTCAAAATAAGGCGAAAGATATTGAAGCCGCACAGCGCG
TATGGAAAGAGTGCCAACGCATGCTAGCTGATGAGTCGATTGATGTAATTCTGTTTGATGAGCTGACGTACATGGTAAGC
TATGGCTACATCGAGCTAGATGAAGTGGTAGAGGCTCTGAGTAACCGTCCTAAAATGCAATCAGTGATCATCACAGGCCG
TGGAGCGCATCGTACTTTAACGGACATGGCCGATACCGTGTCTGAAGTTCGTAACGTTAAACACGCTTTTGAGTCTGGTG
TTAAAGCTCTGCAAGGTGTGGATTGGTAA

Upstream 100 bases:

>100_bases
GAGCTTTCTTTCTCAGCACCGCTTCACCTGTTGGCGAACGACAAATATTCCCCATACAAACCACGAGTATCTTTTTCATC
CGTAATCACCTGTTCTTCCG

Downstream 100 bases:

>100_bases
CAGCCTTCCAACCAGAGGTCCCCGACTCGGTCACTCTTCCCTCTCGAGGATGACGACCACTAGACTGTCTCGCCCTTGAA
CAAGGCACTAATACCTATCG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MVFAIVKLGYDRRNHNLKGFVMSTEDNKEQRHKARQQKVKEQVDARVAAAQEVKGLLLVITGNGKGKSTSGFGTITRAVG
HGKKCAVAQFVKGTWDNGEKNVLQKLDVEFQVMGTGFTWETQNKAKDIEAAQRVWKECQRMLADESIDVILFDELTYMVS
YGYIELDEVVEALSNRPKMQSVIITGRGAHRTLTDMADTVSEVRNVKHAFESGVKALQGVDW

Sequences:

>Translated_222_residues
MVFAIVKLGYDRRNHNLKGFVMSTEDNKEQRHKARQQKVKEQVDARVAAAQEVKGLLLVITGNGKGKSTSGFGTITRAVG
HGKKCAVAQFVKGTWDNGEKNVLQKLDVEFQVMGTGFTWETQNKAKDIEAAQRVWKECQRMLADESIDVILFDELTYMVS
YGYIELDEVVEALSNRPKMQSVIITGRGAHRTLTDMADTVSEVRNVKHAFESGVKALQGVDW
>Mature_222_residues
MVFAIVKLGYDRRNHNLKGFVMSTEDNKEQRHKARQQKVKEQVDARVAAAQEVKGLLLVITGNGKGKSTSGFGTITRAVG
HGKKCAVAQFVKGTWDNGEKNVLQKLDVEFQVMGTGFTWETQNKAKDIEAAQRVWKECQRMLADESIDVILFDELTYMVS
YGYIELDEVVEALSNRPKMQSVIITGRGAHRTLTDMADTVSEVRNVKHAFESGVKALQGVDW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=194, Percent_Identity=61.8556701030928, Blast_Score=266, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 24837; Mature: 24837

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFAIVKLGYDRRNHNLKGFVMSTEDNKEQRHKARQQKVKEQVDARVAAAQEVKGLLLVI
CEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
TGNGKGKSTSGFGTITRAVGHGKKCAVAQFVKGTWDNGEKNVLQKLDVEFQVMGTGFTWE
ECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEECCCEEC
TQNKAKDIEAAQRVWKECQRMLADESIDVILFDELTYMVSYGYIELDEVVEALSNRPKMQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCEEHHHHHHHHHCCCCEE
SVIITGRGAHRTLTDMADTVSEVRNVKHAFESGVKALQGVDW
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVFAIVKLGYDRRNHNLKGFVMSTEDNKEQRHKARQQKVKEQVDARVAAAQEVKGLLLVI
CEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
TGNGKGKSTSGFGTITRAVGHGKKCAVAQFVKGTWDNGEKNVLQKLDVEFQVMGTGFTWE
ECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEECCCEEC
TQNKAKDIEAAQRVWKECQRMLADESIDVILFDELTYMVSYGYIELDEVVEALSNRPKMQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCEEHHHHHHHHHCCCCEE
SVIITGRGAHRTLTDMADTVSEVRNVKHAFESGVKALQGVDW
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]