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The map label for this gene is gacS [H]

Identifier: 218708960

GI number: 218708960

Start: 994192

End: 998580

Strand: Reverse

Name: gacS [H]

Synonym: VS_0964

Alternate gene names: 218708960

Gene position: 998580-994192 (Counterclockwise)

Preceding gene: 218708961

Following gene: 218708957

Centisome position: 30.27

GC content: 45.5

Gene sequence:

>4389_bases
ATGCAAAACAGCGCTTCAAAAACGAAAACGTGGTGTGTCGCCTTTTTATTGAGTTGTCTTTCACTGTTGATGTGGCCACT
GCTCACCTTTGCCGAAAACACCCCACCAGGGAACACATCACCCGCTAGCTCCTTAGCAAACAAAACAGAGAACTCATCGA
GTGACCAAGTCATATTGCGGGTTGGCCTACCTTCTTACGACATGGTCCCCTACAGCTATCAACATAAGACTCCCTCAGGC
AACACTGTTTCTGAAGGGCTACTCATCAGTATGTTGGATCAGGTAGCGGTAAATGCAGGTTTCCAATATCAGATTAAGTT
GTATTCAACATTTAGTGATGTACTGAGTGCATTCGAAAGAGGTGAATTAGATCTGCTAGTCGGCGTCTCTTCGACTAAGG
AGCGCCAAAATTACATGACTTTTAGTGAGCCGATGTTTTCCATAAGACGAGCGGTGATAACCCAAAATAGAAAAATAAAC
GATTTAGATGCGTTGGCAACCGCCAACCTAGCATTGGAGAAAGGGTTTGCGCTCAATGATCTTCTTCCTAGCCTGCTTCC
TGATAGTCAAATTACCACATTAGACAGCACGCAAGCGGCGTTCACGGCGATTCAGGAGAATAGCGTCGATGCGTACATTG
GCGATGCACTTGCACTTTCTGCGTTATTACGAGAACAGCCTCGAGACTCACTAACATTGTCTGTACTTCCTGACCTTCCC
GCAGATCACTTGCATTTCGCGGTCAAAAAAGGAAAGCACAGATTGCTTAGCCGAATCAATTTCGCTTTACAGGACATTAA
GGAAGGTTCACTGCAATCTATTTACAATCAATGGCTTGCTCCATCGCAACATTCGATGCTGCTGAACTATGGAACATTGA
ATTTAACCCAAGATGAAAAGAACTGGCTCGACAGCAACCCTTCCATCCCCGTAGGCACACACTCCAATTGGTACCCTTAC
GACTTTACTAATGAGCAACAGCAACACTCAGGCTTATCTGCTGACATCTTAAACCTAATAAGTAATGTGCTTGGCGTGTC
ATTCGAAAGTACCACTTACCTAACACCAGAAGCGGCCGAGGTCGCGTTCAATAATGGTGAGACAATGGTGCTAACCAACA
TCACACCAACCACAGATAAAGCCCGATACATGGACTTCACTCAAGCTTACAGTTTTGAACCTTGGGTGTTATTGAGTCGC
TCTGATCGCTTAGGCAACTTTGCGCCAAGTGGCACCGAAGCTGTTGGCGTGATTGAAAATTCTGGAGGATCAACAGTTCT
GCCTTCTCTCTGCCTTACTTGCCTAGCCGTCCCTTACATCAATCACGTCAGCGCTTTCCAAGCATTACAGAAAGACGACA
TCAGTTTCGCGCTTGCTTCACTTCATCATGCTGCACCTTTATTGCATCAAGACTATGTAGGGCAATTCAAAATCACTGGC
ACCATTAATGAGCAAAACAGCGCACCACTAGCTCTCGCAGTGAACTTCCGCCATCCCATGCTGTTGAGTATTCTCAACAA
AACCATTGGAGCACTGCCTGCCAATGAATTAGAGCGCTTGGAAAACAAATGGTTAACCTATGAATACCAAGAAGGCTTAT
CACCACGCGAAGTCGCTAAATGGTCGGTGATCATCGGGCTTGGAATCTTTGTGGTCATTTTCGTGATCGTATTTTGGAAC
CGAAAAATGGCGGCTGAAATCGAGCAGCGAAAGATCGCCGAGCAGAGAGCAAAAGCAGCAGAAGCCCATTTGCAAACGCT
GGCCGACAACATTGATGGGGTCGTGCTTAAACATATTCAAACGCACCCTCGACAGCCTTTAGATATCCGGTTTAGCTTTG
TCAGTGCAGGTGTAAGCGATATGTTCGGCTTATCCGTGGATAACGTAAAAGAGCACCCTCAACACCTGTTTGATCTGATC
GCAGAGGATGACTTGCCCCAGTTTGAAACCAGTATGCTCGAAGCTATTGAAACCGGGCATTGGGAAAATGAACAGCGAAT
GCAGTTAGAATCAGGTCAAACTAAATGGGTGAAATTTAATAGCCAAGTATCGAACAGTAAAACCATTGAGTGGAATACGG
TGATAACAGACATCACCCTACTAAAAAAACAACAGCAAGCTTTAGACAACGCACGCCAAAAAGCAGAAAGTGCAACGGCT
GCAAAGTCGCAATTCTTAGCGACCATTAGCCACGAGGTTCGCACCCCGATTAGTGGGATCTTAGGGCTGTTGGAATTAAT
GCAGGAACATCAGCTGAGTGAAGAGTTACTGAACTTACACGGTGGGTTAAATCAGTCGGCTCGGAACTTACTGCACATCG
TTAATGACGTACTCGATTACTCCAAGATTGAAGCAGGAAAACTGGATCTTAACCCGACCGAAATTGAGCTCGGCAAAGTA
CTCGCCCGTATCGTGCAACCGCAATCCATTCATGCACAGCAAAAAGGCTTAGCCTTCCACTATTGGCAAGACCCAAACCT
CGCTCAGTGGTTGTTTGCAGACGATATACGACTCCATCAGATTCTAAACAATTTCCTTAACAATGCGATTAAGTTCACCG
AACATGGCACTATTTCATTGCATATTGATGTGATTGAGCAGAACGAACATCAGCAGAAAGTTAGCCTCACGGTTTCCGAT
ACGGGCATCGGCATCCCGAAAGACAGACAACAAAGCTTATTCCAACCTTTTGAACAAGTCGACAAAACCACTAGCCGCCG
TTTTGGTGGCACAGGGCTTGGACTGTCTATCGCTTTGAAATTGATAGAACAGATGGATGGCAACATAGAACTGTCGAGTG
AAGAAGGAAAAGGCAGCCACTTTACGGTAACCGTTACCCTCCCAACTTGTACTCCTGAACATGCAGTAAGCAACGCTTTG
GCTCTACGACAAACGCTGATTTTTCCTTCAGAGGGTGAGAATTCTATTGAGCTAGATGTCGGTAATCACTCAAACGAGGT
ATACGTCGTCGGCTACGTTCTGCAACAAGAAGAACTGTGTCGATATCTGAAACACTTCGATCTTGAACCAAAAGTTCTGC
ACATTAATCAAAAGCACCTACTCAAAGAGATGGTCGTCAAACATCAGCCCAAACACATCTTTGTCGCGATGTCGGTTTGG
CAACAACTGGCGATTAGCGATGCTTGGATTCAGCAGCATACGGGTTCAACACGCTTCACCGTAATCAACCAAAACCCAAT
GCTCTCACCAGAGCCTTTAGGTAACTCTTGGTGCTTGTCGGTAAATCCGCTGCTGCCCGATAACCTTGTTCATGTTTTAA
CGAAACCCGTCAGTCACAACAATCTACTCTCATCATTAGACAACGAAACCAAAGCGCCTATCGCTATCGAGACTCGCGAA
CAAGCCGAGAATAATGGCCGACTGATTCTTGTTGCGGAAGACCACCCGATCAATCAGCAAGTCATCGCCAAGCAGCTTGA
GAGTATTGGTGTCCACGCTGATATTTTCGATAACGGAGTGCTAGCGCTGAATGCTTTAAAAAATAAACGTTATGGTTTGC
TTCTCACCGATTGCCATATGCCGGAGATGGACGGTTACACGCTTGCCTCAAGCATTCGTCAGATAGAACAACGCAATGAA
GAACTAAATCAAGAAACTCAAAAGTTGCCTATCGTCGCGTTGACGGCGAATGCGGTTCAGGGTGAAGATGCCAACTGTTA
TGCACACGGCATGGATGATTTCCTAGTTAAACCTGTTTCCATTAAGCAAATGAAGCTGACCATTGAAAAATGGCTACCCG
CAATCCACGATTTAGATCCGACGCTTGAAACCGATATTTCTGATGCAGAAAAGCCAGACTCGCAAAATCAGGACACAAGC
TCTTCGTCAAACGCTTTACCTGCAACTCAAGAAACCAATGAGTTTTCAATGCTGTTCCAAGGCATTGAACAGAGCTTTGC
GGAATCGGCAGAAAATAACAACTCAGAGACAATCGAAGATGTTGCCACCACAGTCCCTCAAGATTCACTCCACGAGACCA
ATAGCCCCATCATCAACTACACCGCGCTCTACGATCTATTTGAAGATCACGATGTGGTGATGACCTTACTCGACGAGTTT
GCCGCAAGTTTTCTTGCAGATAATGAACAGATAAAAGCCCAGTGGGCTAATAAGGAATATAAGGGACTAAAAACCACATC
ACACCGACTCAAAGGTGCTGCTAAAATGGTGGCATGTGACGCGATTGCTTCTCCGCTCGCAATCATTGAAGCACAAGCAA
ACGACCTAGTAACCGAAGCCACAGACTTAGATCAAGTCGAATCAGAAATTGAAGCATCAATCTCGGAAGCAACTAACACA
TTCGAACGGTTTACAGAGGAGATAAACCAACTACGTCAGACAAAAGAAAAGGCTTACTCTTATGAGTAA

Upstream 100 bases:

>100_bases
GATAATTTTTCACTCCCCACACTAACTAAAGCCCCTTTGGCTGCCGTTAGTTAAGCATGGCGATATTCTAAAATCAGCAA
GCAAACGACAGGATGTCTTT

Downstream 100 bases:

>100_bases
GCCTTAGAGGTTATTGCGTCAATACAGACAGCTCTCGCCGGATTATGCAGCGGGAGCGTTATTCACTAGAATTTCGCGAA
TAGACTTAAGTGTCGCTTCA

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1462; Mature: 1462

Protein sequence:

>1462_residues
MQNSASKTKTWCVAFLLSCLSLLMWPLLTFAENTPPGNTSPASSLANKTENSSSDQVILRVGLPSYDMVPYSYQHKTPSG
NTVSEGLLISMLDQVAVNAGFQYQIKLYSTFSDVLSAFERGELDLLVGVSSTKERQNYMTFSEPMFSIRRAVITQNRKIN
DLDALATANLALEKGFALNDLLPSLLPDSQITTLDSTQAAFTAIQENSVDAYIGDALALSALLREQPRDSLTLSVLPDLP
ADHLHFAVKKGKHRLLSRINFALQDIKEGSLQSIYNQWLAPSQHSMLLNYGTLNLTQDEKNWLDSNPSIPVGTHSNWYPY
DFTNEQQQHSGLSADILNLISNVLGVSFESTTYLTPEAAEVAFNNGETMVLTNITPTTDKARYMDFTQAYSFEPWVLLSR
SDRLGNFAPSGTEAVGVIENSGGSTVLPSLCLTCLAVPYINHVSAFQALQKDDISFALASLHHAAPLLHQDYVGQFKITG
TINEQNSAPLALAVNFRHPMLLSILNKTIGALPANELERLENKWLTYEYQEGLSPREVAKWSVIIGLGIFVVIFVIVFWN
RKMAAEIEQRKIAEQRAKAAEAHLQTLADNIDGVVLKHIQTHPRQPLDIRFSFVSAGVSDMFGLSVDNVKEHPQHLFDLI
AEDDLPQFETSMLEAIETGHWENEQRMQLESGQTKWVKFNSQVSNSKTIEWNTVITDITLLKKQQQALDNARQKAESATA
AKSQFLATISHEVRTPISGILGLLELMQEHQLSEELLNLHGGLNQSARNLLHIVNDVLDYSKIEAGKLDLNPTEIELGKV
LARIVQPQSIHAQQKGLAFHYWQDPNLAQWLFADDIRLHQILNNFLNNAIKFTEHGTISLHIDVIEQNEHQQKVSLTVSD
TGIGIPKDRQQSLFQPFEQVDKTTSRRFGGTGLGLSIALKLIEQMDGNIELSSEEGKGSHFTVTVTLPTCTPEHAVSNAL
ALRQTLIFPSEGENSIELDVGNHSNEVYVVGYVLQQEELCRYLKHFDLEPKVLHINQKHLLKEMVVKHQPKHIFVAMSVW
QQLAISDAWIQQHTGSTRFTVINQNPMLSPEPLGNSWCLSVNPLLPDNLVHVLTKPVSHNNLLSSLDNETKAPIAIETRE
QAENNGRLILVAEDHPINQQVIAKQLESIGVHADIFDNGVLALNALKNKRYGLLLTDCHMPEMDGYTLASSIRQIEQRNE
ELNQETQKLPIVALTANAVQGEDANCYAHGMDDFLVKPVSIKQMKLTIEKWLPAIHDLDPTLETDISDAEKPDSQNQDTS
SSSNALPATQETNEFSMLFQGIEQSFAESAENNNSETIEDVATTVPQDSLHETNSPIINYTALYDLFEDHDVVMTLLDEF
AASFLADNEQIKAQWANKEYKGLKTTSHRLKGAAKMVACDAIASPLAIIEAQANDLVTEATDLDQVESEIEASISEATNT
FERFTEEINQLRQTKEKAYSYE

Sequences:

>Translated_1462_residues
MQNSASKTKTWCVAFLLSCLSLLMWPLLTFAENTPPGNTSPASSLANKTENSSSDQVILRVGLPSYDMVPYSYQHKTPSG
NTVSEGLLISMLDQVAVNAGFQYQIKLYSTFSDVLSAFERGELDLLVGVSSTKERQNYMTFSEPMFSIRRAVITQNRKIN
DLDALATANLALEKGFALNDLLPSLLPDSQITTLDSTQAAFTAIQENSVDAYIGDALALSALLREQPRDSLTLSVLPDLP
ADHLHFAVKKGKHRLLSRINFALQDIKEGSLQSIYNQWLAPSQHSMLLNYGTLNLTQDEKNWLDSNPSIPVGTHSNWYPY
DFTNEQQQHSGLSADILNLISNVLGVSFESTTYLTPEAAEVAFNNGETMVLTNITPTTDKARYMDFTQAYSFEPWVLLSR
SDRLGNFAPSGTEAVGVIENSGGSTVLPSLCLTCLAVPYINHVSAFQALQKDDISFALASLHHAAPLLHQDYVGQFKITG
TINEQNSAPLALAVNFRHPMLLSILNKTIGALPANELERLENKWLTYEYQEGLSPREVAKWSVIIGLGIFVVIFVIVFWN
RKMAAEIEQRKIAEQRAKAAEAHLQTLADNIDGVVLKHIQTHPRQPLDIRFSFVSAGVSDMFGLSVDNVKEHPQHLFDLI
AEDDLPQFETSMLEAIETGHWENEQRMQLESGQTKWVKFNSQVSNSKTIEWNTVITDITLLKKQQQALDNARQKAESATA
AKSQFLATISHEVRTPISGILGLLELMQEHQLSEELLNLHGGLNQSARNLLHIVNDVLDYSKIEAGKLDLNPTEIELGKV
LARIVQPQSIHAQQKGLAFHYWQDPNLAQWLFADDIRLHQILNNFLNNAIKFTEHGTISLHIDVIEQNEHQQKVSLTVSD
TGIGIPKDRQQSLFQPFEQVDKTTSRRFGGTGLGLSIALKLIEQMDGNIELSSEEGKGSHFTVTVTLPTCTPEHAVSNAL
ALRQTLIFPSEGENSIELDVGNHSNEVYVVGYVLQQEELCRYLKHFDLEPKVLHINQKHLLKEMVVKHQPKHIFVAMSVW
QQLAISDAWIQQHTGSTRFTVINQNPMLSPEPLGNSWCLSVNPLLPDNLVHVLTKPVSHNNLLSSLDNETKAPIAIETRE
QAENNGRLILVAEDHPINQQVIAKQLESIGVHADIFDNGVLALNALKNKRYGLLLTDCHMPEMDGYTLASSIRQIEQRNE
ELNQETQKLPIVALTANAVQGEDANCYAHGMDDFLVKPVSIKQMKLTIEKWLPAIHDLDPTLETDISDAEKPDSQNQDTS
SSSNALPATQETNEFSMLFQGIEQSFAESAENNNSETIEDVATTVPQDSLHETNSPIINYTALYDLFEDHDVVMTLLDEF
AASFLADNEQIKAQWANKEYKGLKTTSHRLKGAAKMVACDAIASPLAIIEAQANDLVTEATDLDQVESEIEASISEATNT
FERFTEEINQLRQTKEKAYSYE
>Mature_1462_residues
MQNSASKTKTWCVAFLLSCLSLLMWPLLTFAENTPPGNTSPASSLANKTENSSSDQVILRVGLPSYDMVPYSYQHKTPSG
NTVSEGLLISMLDQVAVNAGFQYQIKLYSTFSDVLSAFERGELDLLVGVSSTKERQNYMTFSEPMFSIRRAVITQNRKIN
DLDALATANLALEKGFALNDLLPSLLPDSQITTLDSTQAAFTAIQENSVDAYIGDALALSALLREQPRDSLTLSVLPDLP
ADHLHFAVKKGKHRLLSRINFALQDIKEGSLQSIYNQWLAPSQHSMLLNYGTLNLTQDEKNWLDSNPSIPVGTHSNWYPY
DFTNEQQQHSGLSADILNLISNVLGVSFESTTYLTPEAAEVAFNNGETMVLTNITPTTDKARYMDFTQAYSFEPWVLLSR
SDRLGNFAPSGTEAVGVIENSGGSTVLPSLCLTCLAVPYINHVSAFQALQKDDISFALASLHHAAPLLHQDYVGQFKITG
TINEQNSAPLALAVNFRHPMLLSILNKTIGALPANELERLENKWLTYEYQEGLSPREVAKWSVIIGLGIFVVIFVIVFWN
RKMAAEIEQRKIAEQRAKAAEAHLQTLADNIDGVVLKHIQTHPRQPLDIRFSFVSAGVSDMFGLSVDNVKEHPQHLFDLI
AEDDLPQFETSMLEAIETGHWENEQRMQLESGQTKWVKFNSQVSNSKTIEWNTVITDITLLKKQQQALDNARQKAESATA
AKSQFLATISHEVRTPISGILGLLELMQEHQLSEELLNLHGGLNQSARNLLHIVNDVLDYSKIEAGKLDLNPTEIELGKV
LARIVQPQSIHAQQKGLAFHYWQDPNLAQWLFADDIRLHQILNNFLNNAIKFTEHGTISLHIDVIEQNEHQQKVSLTVSD
TGIGIPKDRQQSLFQPFEQVDKTTSRRFGGTGLGLSIALKLIEQMDGNIELSSEEGKGSHFTVTVTLPTCTPEHAVSNAL
ALRQTLIFPSEGENSIELDVGNHSNEVYVVGYVLQQEELCRYLKHFDLEPKVLHINQKHLLKEMVVKHQPKHIFVAMSVW
QQLAISDAWIQQHTGSTRFTVINQNPMLSPEPLGNSWCLSVNPLLPDNLVHVLTKPVSHNNLLSSLDNETKAPIAIETRE
QAENNGRLILVAEDHPINQQVIAKQLESIGVHADIFDNGVLALNALKNKRYGLLLTDCHMPEMDGYTLASSIRQIEQRNE
ELNQETQKLPIVALTANAVQGEDANCYAHGMDDFLVKPVSIKQMKLTIEKWLPAIHDLDPTLETDISDAEKPDSQNQDTS
SSSNALPATQETNEFSMLFQGIEQSFAESAENNNSETIEDVATTVPQDSLHETNSPIINYTALYDLFEDHDVVMTLLDEF
AASFLADNEQIKAQWANKEYKGLKTTSHRLKGAAKMVACDAIASPLAIIEAQANDLVTEATDLDQVESEIEASISEATNT
FERFTEEINQLRQTKEKAYSYE

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=561, Percent_Identity=29.2335115864528, Blast_Score=223, Evalue=7e-59,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=40.7843137254902, Blast_Score=191, Evalue=3e-49,
Organism=Escherichia coli, GI1788713, Length=883, Percent_Identity=22.083805209513, Blast_Score=183, Evalue=6e-47,
Organism=Escherichia coli, GI48994928, Length=258, Percent_Identity=35.6589147286822, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=34.0163934426229, Blast_Score=126, Evalue=1e-29,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=30.7017543859649, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=28, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=29.0748898678414, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=28, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1790861, Length=253, Percent_Identity=26.8774703557312, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=26.1410788381743, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=27.7310924369748, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=23.728813559322, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=25.4980079681275, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1790300, Length=253, Percent_Identity=28.4584980237154, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=319, Percent_Identity=24.4514106583072, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=51.3513513513513, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322000, Length=175, Percent_Identity=26.2857142857143, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 162829; Mature: 162829

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNSASKTKTWCVAFLLSCLSLLMWPLLTFAENTPPGNTSPASSLANKTENSSSDQVILR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEE
VGLPSYDMVPYSYQHKTPSGNTVSEGLLISMLDQVAVNAGFQYQIKLYSTFSDVLSAFER
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHC
GELDLLVGVSSTKERQNYMTFSEPMFSIRRAVITQNRKINDLDALATANLALEKGFALND
CCEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHH
LLPSLLPDSQITTLDSTQAAFTAIQENSVDAYIGDALALSALLREQPRDSLTLSVLPDLP
HHHHHCCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
ADHLHFAVKKGKHRLLSRINFALQDIKEGSLQSIYNQWLAPSQHSMLLNYGTLNLTQDEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECEEEECCCHH
NWLDSNPSIPVGTHSNWYPYDFTNEQQQHSGLSADILNLISNVLGVSFESTTYLTPEAAE
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEECCCHHH
VAFNNGETMVLTNITPTTDKARYMDFTQAYSFEPWVLLSRSDRLGNFAPSGTEAVGVIEN
EEECCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEEEC
SGGSTVLPSLCLTCLAVPYINHVSAFQALQKDDISFALASLHHAAPLLHQDYVGQFKITG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
TINEQNSAPLALAVNFRHPMLLSILNKTIGALPANELERLENKWLTYEYQEGLSPREVAK
EECCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEHHCCCCHHHHHH
WSVIIGLGIFVVIFVIVFWNRKMAAEIEQRKIAEQRAKAAEAHLQTLADNIDGVVLKHIQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
THPRQPLDIRFSFVSAGVSDMFGLSVDNVKEHPQHLFDLIAEDDLPQFETSMLEAIETGH
HCCCCCCEEEEHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
WENEQRMQLESGQTKWVKFNSQVSNSKTIEWNTVITDITLLKKQQQALDNARQKAESATA
CCCHHHHHHCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKSQFLATISHEVRTPISGILGLLELMQEHQLSEELLNLHGGLNQSARNLLHIVNDVLDY
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SKIEAGKLDLNPTEIELGKVLARIVQPQSIHAQQKGLAFHYWQDPNLAQWLFADDIRLHQ
HHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHH
ILNNFLNNAIKFTEHGTISLHIDVIEQNEHQQKVSLTVSDTGIGIPKDRQQSLFQPFEQV
HHHHHHHHHEEEECCCEEEEEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHH
DKTTSRRFGGTGLGLSIALKLIEQMDGNIELSSEEGKGSHFTVTVTLPTCTPEHAVSNAL
HHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCHHHHHHHHH
ALRQTLIFPSEGENSIELDVGNHSNEVYVVGYVLQQEELCRYLKHFDLEPKVLHINQKHL
HHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEECCHHHH
LKEMVVKHQPKHIFVAMSVWQQLAISDAWIQQHTGSTRFTVINQNPMLSPEPLGNSWCLS
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEE
VNPLLPDNLVHVLTKPVSHNNLLSSLDNETKAPIAIETREQAENNGRLILVAEDHPINQQ
ECCCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEHHHHCCCCEEEEEECCCCCCHH
VIAKQLESIGVHADIFDNGVLALNALKNKRYGLLLTDCHMPEMDGYTLASSIRQIEQRNE
HHHHHHHHCCCEEEECCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
ELNQETQKLPIVALTANAVQGEDANCYAHGMDDFLVKPVSIKQMKLTIEKWLPAIHDLDP
HHHHHHHHCCEEEEEECCCCCCCCCEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
TLETDISDAEKPDSQNQDTSSSSNALPATQETNEFSMLFQGIEQSFAESAENNNSETIED
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VATTVPQDSLHETNSPIINYTALYDLFEDHDVVMTLLDEFAASFLADNEQIKAQWANKEY
HHHHCCCHHHHCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHH
KGLKTTSHRLKGAAKMVACDAIASPLAIIEAQANDLVTEATDLDQVESEIEASISEATNT
CCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FERFTEEINQLRQTKEKAYSYE
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQNSASKTKTWCVAFLLSCLSLLMWPLLTFAENTPPGNTSPASSLANKTENSSSDQVILR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEE
VGLPSYDMVPYSYQHKTPSGNTVSEGLLISMLDQVAVNAGFQYQIKLYSTFSDVLSAFER
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHC
GELDLLVGVSSTKERQNYMTFSEPMFSIRRAVITQNRKINDLDALATANLALEKGFALND
CCEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHH
LLPSLLPDSQITTLDSTQAAFTAIQENSVDAYIGDALALSALLREQPRDSLTLSVLPDLP
HHHHHCCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
ADHLHFAVKKGKHRLLSRINFALQDIKEGSLQSIYNQWLAPSQHSMLLNYGTLNLTQDEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECEEEECCCHH
NWLDSNPSIPVGTHSNWYPYDFTNEQQQHSGLSADILNLISNVLGVSFESTTYLTPEAAE
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEECCCHHH
VAFNNGETMVLTNITPTTDKARYMDFTQAYSFEPWVLLSRSDRLGNFAPSGTEAVGVIEN
EEECCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEEEC
SGGSTVLPSLCLTCLAVPYINHVSAFQALQKDDISFALASLHHAAPLLHQDYVGQFKITG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
TINEQNSAPLALAVNFRHPMLLSILNKTIGALPANELERLENKWLTYEYQEGLSPREVAK
EECCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEHHCCCCHHHHHH
WSVIIGLGIFVVIFVIVFWNRKMAAEIEQRKIAEQRAKAAEAHLQTLADNIDGVVLKHIQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
THPRQPLDIRFSFVSAGVSDMFGLSVDNVKEHPQHLFDLIAEDDLPQFETSMLEAIETGH
HCCCCCCEEEEHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
WENEQRMQLESGQTKWVKFNSQVSNSKTIEWNTVITDITLLKKQQQALDNARQKAESATA
CCCHHHHHHCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKSQFLATISHEVRTPISGILGLLELMQEHQLSEELLNLHGGLNQSARNLLHIVNDVLDY
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SKIEAGKLDLNPTEIELGKVLARIVQPQSIHAQQKGLAFHYWQDPNLAQWLFADDIRLHQ
HHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHH
ILNNFLNNAIKFTEHGTISLHIDVIEQNEHQQKVSLTVSDTGIGIPKDRQQSLFQPFEQV
HHHHHHHHHEEEECCCEEEEEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHH
DKTTSRRFGGTGLGLSIALKLIEQMDGNIELSSEEGKGSHFTVTVTLPTCTPEHAVSNAL
HHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCHHHHHHHHH
ALRQTLIFPSEGENSIELDVGNHSNEVYVVGYVLQQEELCRYLKHFDLEPKVLHINQKHL
HHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEECCHHHH
LKEMVVKHQPKHIFVAMSVWQQLAISDAWIQQHTGSTRFTVINQNPMLSPEPLGNSWCLS
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEE
VNPLLPDNLVHVLTKPVSHNNLLSSLDNETKAPIAIETREQAENNGRLILVAEDHPINQQ
ECCCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEHHHHCCCCEEEEEECCCCCCHH
VIAKQLESIGVHADIFDNGVLALNALKNKRYGLLLTDCHMPEMDGYTLASSIRQIEQRNE
HHHHHHHHCCCEEEECCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
ELNQETQKLPIVALTANAVQGEDANCYAHGMDDFLVKPVSIKQMKLTIEKWLPAIHDLDP
HHHHHHHHCCEEEEEECCCCCCCCCEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
TLETDISDAEKPDSQNQDTSSSSNALPATQETNEFSMLFQGIEQSFAESAENNNSETIED
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VATTVPQDSLHETNSPIINYTALYDLFEDHDVVMTLLDEFAASFLADNEQIKAQWANKEY
HHHHCCCHHHHCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHH
KGLKTTSHRLKGAAKMVACDAIASPLAIIEAQANDLVTEATDLDQVESEIEASISEATNT
CCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FERFTEEINQLRQTKEKAYSYE
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]