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The map label for this gene is sodB [H]

Identifier: 218708957

GI number: 218708957

Start: 992228

End: 992812

Strand: Reverse

Name: sodB [H]

Synonym: VS_0961

Alternate gene names: 218708957

Gene position: 992812-992228 (Counterclockwise)

Preceding gene: 218708960

Following gene: 218708956

Centisome position: 30.09

GC content: 45.64

Gene sequence:

>585_bases
ATGGCATTTGAACTACCGGCTCTTCCTTACGCGAAAGACGCGCTAGAACCACACATCTCAGCAGAAACGCTAGATTTCCA
CCACGGTAAGCACCACAACACTTACGTTGTTAAGCTAAACGGTCTTATCCCAGGTACTGAGTTTGAAGGCAAAACACTAG
AAGAAATCGTTAAGACTTCTACTGGTGGTGTTTTCAATAACGCTGCTCAAATCTGGAACCACACGTTCTACTGGCACTGT
CTTGCTCCTAAAGCAGGCGGCGAACCAACAGGCGCGGTTGCAGAAGCGATCAACGCTGCATTCGGTTCTTTCGAAGAATT
CAAAGCGAAATTCACTGATTCAGCAATCAACAACTTCGGTTCTTCTTGGACTTGGTTAGTTAAGAAAGCTGACGGTTCTC
TAGACATCGTTAACACTTCTAACGCTGCGACTCCTCTAACAGAAGAAGGTGTTACTCCACTTCTAACTGTTGACCTATGG
GAACACGCTTACTACATCGATTTCCGCAATGTTCGCCCTGACTACATGGCTGCATTCTGGAACCTAGTAAACTGGTCTTT
CGTAGAAGAGAACCTAGCTAAGTAA

Upstream 100 bases:

>100_bases
GCAAATTGACCGTGGTTGGCAATATAGCGAGCCATGAATAATAATATCACTGGAAGCAATCGAAAGAGTTAACTCTTTCA
TATCAATGGAGAATTGAGCA

Downstream 100 bases:

>100_bases
TTATTACTTACGCTGCGCTATTTATAGCAAGTTATCTATTGAAAGCTCATGCCTCGGCGTGAGCTTTTTTGTATCTGTCG
TATTCTAATCAATGCGAACA

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MAFELPALPYAKDALEPHISAETLDFHHGKHHNTYVVKLNGLIPGTEFEGKTLEEIVKTSTGGVFNNAAQIWNHTFYWHC
LAPKAGGEPTGAVAEAINAAFGSFEEFKAKFTDSAINNFGSSWTWLVKKADGSLDIVNTSNAATPLTEEGVTPLLTVDLW
EHAYYIDFRNVRPDYMAAFWNLVNWSFVEENLAK

Sequences:

>Translated_194_residues
MAFELPALPYAKDALEPHISAETLDFHHGKHHNTYVVKLNGLIPGTEFEGKTLEEIVKTSTGGVFNNAAQIWNHTFYWHC
LAPKAGGEPTGAVAEAINAAFGSFEEFKAKFTDSAINNFGSSWTWLVKKADGSLDIVNTSNAATPLTEEGVTPLLTVDLW
EHAYYIDFRNVRPDYMAAFWNLVNWSFVEENLAK
>Mature_193_residues
AFELPALPYAKDALEPHISAETLDFHHGKHHNTYVVKLNGLIPGTEFEGKTLEEIVKTSTGGVFNNAAQIWNHTFYWHCL
APKAGGEPTGAVAEAINAAFGSFEEFKAKFTDSAINNFGSSWTWLVKKADGSLDIVNTSNAATPLTEEGVTPLLTVDLWE
HAYYIDFRNVRPDYMAAFWNLVNWSFVEENLAK

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=196, Percent_Identity=42.3469387755102, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI67782305, Length=196, Percent_Identity=42.3469387755102, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI67782309, Length=188, Percent_Identity=37.7659574468085, Blast_Score=123, Evalue=8e-29,
Organism=Escherichia coli, GI1787946, Length=193, Percent_Identity=74.0932642487047, Blast_Score=305, Evalue=1e-84,
Organism=Escherichia coli, GI1790342, Length=198, Percent_Identity=41.9191919191919, Blast_Score=156, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17506561, Length=193, Percent_Identity=38.860103626943, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17569479, Length=192, Percent_Identity=39.5833333333333, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6321796, Length=203, Percent_Identity=35.9605911330049, Blast_Score=115, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136812, Length=188, Percent_Identity=37.2340425531915, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 21567; Mature: 21436

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFELPALPYAKDALEPHISAETLDFHHGKHHNTYVVKLNGLIPGTEFEGKTLEEIVKTS
CCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHC
TGGVFNNAAQIWNHTFYWHCLAPKAGGEPTGAVAEAINAAFGSFEEFKAKFTDSAINNFG
CCCCHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
SSWTWLVKKADGSLDIVNTSNAATPLTEEGVTPLLTVDLWEHAYYIDFRNVRPDYMAAFW
CCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHH
NLVNWSFVEENLAK
HHHHHHHHHHHHCC
>Mature Secondary Structure 
AFELPALPYAKDALEPHISAETLDFHHGKHHNTYVVKLNGLIPGTEFEGKTLEEIVKTS
CCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHC
TGGVFNNAAQIWNHTFYWHCLAPKAGGEPTGAVAEAINAAFGSFEEFKAKFTDSAINNFG
CCCCHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
SSWTWLVKKADGSLDIVNTSNAATPLTEEGVTPLLTVDLWEHAYYIDFRNVRPDYMAAFW
CCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHH
NLVNWSFVEENLAK
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3542995 [H]