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The map label for this gene is msrB [H]

Identifier: 218708931

GI number: 218708931

Start: 960011

End: 960430

Strand: Direct

Name: msrB [H]

Synonym: VS_0933

Alternate gene names: 218708931

Gene position: 960011-960430 (Clockwise)

Preceding gene: 218708921

Following gene: 218708933

Centisome position: 29.1

GC content: 44.05

Gene sequence:

>420_bases
GTGATTCAAAAGGGAGGAAATATGATAAAGCCTGATGAATACTGGCGTGAACGCCTAACGGACGATGAATTTTCTGTGTG
TCGTCAACGTGGTACCGAAGCCCCATATAGCGGTAAGTTACTGCACAACCATAAGACGGGTGTCTATAGCTGCACATGCT
GTGAAAGCCCTTTGTTTCTGTCGGATAACAAATATGATTCAGGGTGCGGTTGGCCAAGCTTTGATGCCCCAGTGAATGAT
GAAGCAGTACGCTATATAGAAGATCTAAGTCACGGAATGAAGCGTGTAGAGATCCGTTGTACCGCTTGTGATAGCCATTT
AGGTCACGTTTTTCCTGATGGTCCGAAGACAACCGGTGAACGGTTCTGTGTTAATTCTGTGTCGTTAATTTTCAACAAAA
ATGACGAAACTACCAAATAA

Upstream 100 bases:

>100_bases
ATGTTTCCTGGTGAGAAAGTATGTGCTACAAAACGACTCATATGCAAGCCTTTATAGAAAAAAGTAAATATAATAACTGA
TAATGTGGAGAGATATTAAC

Downstream 100 bases:

>100_bases
CTTGTCACAATTGTCTAATCCTTACAGGCGTATTTGTTGATTGAGTGGTACTGAACGACCCAAGAGTTAAGTATTTCAGA
GTTATCTCTAGTACAAATAA

Product: peptide methionine sulfoxide reductase MsrB

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MIQKGGNMIKPDEYWRERLTDDEFSVCRQRGTEAPYSGKLLHNHKTGVYSCTCCESPLFLSDNKYDSGCGWPSFDAPVND
EAVRYIEDLSHGMKRVEIRCTACDSHLGHVFPDGPKTTGERFCVNSVSLIFNKNDETTK

Sequences:

>Translated_139_residues
MIQKGGNMIKPDEYWRERLTDDEFSVCRQRGTEAPYSGKLLHNHKTGVYSCTCCESPLFLSDNKYDSGCGWPSFDAPVND
EAVRYIEDLSHGMKRVEIRCTACDSHLGHVFPDGPKTTGERFCVNSVSLIFNKNDETTK
>Mature_139_residues
MIQKGGNMIKPDEYWRERLTDDEFSVCRQRGTEAPYSGKLLHNHKTGVYSCTCCESPLFLSDNKYDSGCGWPSFDAPVND
EAVRYIEDLSHGMKRVEIRCTACDSHLGHVFPDGPKTTGERFCVNSVSLIFNKNDETTK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=135, Percent_Identity=42.2222222222222, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI301336162, Length=135, Percent_Identity=42.2222222222222, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI73089054, Length=135, Percent_Identity=42.2222222222222, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI37620216, Length=135, Percent_Identity=42.2222222222222, Blast_Score=135, Evalue=7e-33,
Organism=Homo sapiens, GI117606353, Length=125, Percent_Identity=49.6, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=61.3445378151261, Blast_Score=168, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17553450, Length=136, Percent_Identity=47.7941176470588, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=136, Percent_Identity=47.7941176470588, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6319816, Length=131, Percent_Identity=41.9847328244275, Blast_Score=97, Evalue=9e-22,
Organism=Drosophila melanogaster, GI221378664, Length=140, Percent_Identity=41.4285714285714, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24645799, Length=139, Percent_Identity=41.0071942446043, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45553335, Length=139, Percent_Identity=41.0071942446043, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356369, Length=139, Percent_Identity=41.0071942446043, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI221378662, Length=147, Percent_Identity=38.0952380952381, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24645801, Length=138, Percent_Identity=39.8550724637681, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24645804, Length=138, Percent_Identity=39.8550724637681, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15733; Mature: 15733

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQKGGNMIKPDEYWRERLTDDEFSVCRQRGTEAPYSGKLLHNHKTGVYSCTCCESPLFL
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCCEEE
SDNKYDSGCGWPSFDAPVNDEAVRYIEDLSHGMKRVEIRCTACDSHLGHVFPDGPKTTGE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCCCCCCCC
RFCVNSVSLIFNKNDETTK
EEECCCEEEEECCCCCCCC
>Mature Secondary Structure
MIQKGGNMIKPDEYWRERLTDDEFSVCRQRGTEAPYSGKLLHNHKTGVYSCTCCESPLFL
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCCEEE
SDNKYDSGCGWPSFDAPVNDEAVRYIEDLSHGMKRVEIRCTACDSHLGHVFPDGPKTTGE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCCCCCCCC
RFCVNSVSLIFNKNDETTK
EEECCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]