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The map label for this gene is flhF [H]

Identifier: 218708838

GI number: 218708838

Start: 860326

End: 861837

Strand: Direct

Name: flhF [H]

Synonym: VS_0838

Alternate gene names: 218708838

Gene position: 860326-861837 (Clockwise)

Preceding gene: 218708837

Following gene: 218708839

Centisome position: 26.08

GC content: 46.83

Gene sequence:

>1512_bases
TTGAAAATTAAACGATTTTTTGCAAAAGATATGCGAACAGCTCTGCTCCAAGTTAAAGAAGAACTTGGCTCAGAAGCGGT
GATCATGTCTAACAAAAAGGTCGCAGGTGGTGTGGAAATTGTTGCCGCTATTGATGGCGATTCCAGCCCGTCGACAGCAA
GTCCCAGACTCAATAAACCTCAGCAGCCTACGCAAAGCCAGTACACTCAAATGTCTGAGCCCAAATTGCCAACTGGGCGT
CGTCAATTAGATGATGACAAGGTTAGCATCCAGCCGAATGCAGAAGGTGGACGCTCAATGACCAAGCGCTTTGCAAATAT
GCTAAAGCAATACAGTCATGGCGCCGACGATGAGCAACAACATCGCGCTGAAAATGAAGACTCGTTATCAGCATTGCTCA
ATCGCCAGTCAAGTAACGGTCATCAACCTCAGAGTAGCCAGCACTCTAGCGGCACCCTTGACTCGGCCTTTGCTCGTGAA
ACGGGTTTATCTAAATTGATTGCCGAAGATCGCAGAGTAGAGCGTCCAGCACCTCGCTTAGATCCTACCCGTTATGATCG
TGGTCGTGAGAATGCTCAATCCAAAGGTTCGGATACTGAAATGGAAACGATGCGTGACGAGATGACTTCAATTCGTCGTT
TGTTAGAGCATCAAGTCTCTGGGCTCATGTGGCAAGAAGTCGAACGTCGCGAACCTTTGCGAGCGATGCTTATCAAGCGC
CTAGAACGTATGGGTGTTTCGGCAGAACTCGCCGATCAAATGGCCTGTTACATTCCAGAAGACACAAAACCAGCACGAGC
ATGGAAAGCCTTGCTTGCTCTGGTCGCTGATCAAATCTCAGTAACACAAAAAGATATTTTAAAACGCGGCGGTATTGTGG
CCTTACTTGGCCCGACTGGCGTAGGTAAAACAACAACCGTTGCTAAGCTCGCAGCCCGCGCAGCAATGGAGTACGGTGCA
GACAACGTAGCGCTTGTGACAACGGACACATATCGCATAGGTGCACATGAGCAGTTATCGATTTATGGTCGAATTATGGG
TTGTCCTGTAAGAGTTGCTAAAGATTCTAGTGAATTGGCCGATGTAATATATCAGTTACGTAATCGTCGCCTGATTCTAG
TCGATACTGCAGGTATGGGGCAGCGAGATGTTCGCCTATCTGAGCAGTTAGACACATTGATGCAAGAGAGTGGTTCCGTT
ATCAATAGTTACCTTGTGTTACCCGCAACCGCGCAACGCAAAGTACTACAAGAAACCATTGAACACTTTAGAAGAATCCC
GCTGTCGGGATGCATCCTGACGAAGCTGGACGAATCGCTTAGTTTGGGTGAGTTCATCAGTGTGGTAATACAAAATGCAT
TGCCAGTTGCTTATATAGCAAATGGTCAACGAGTTCCTGAAGATATCGTTATTGCTCAGCCAAAGTACATGATTGCTAAG
GCCAATGAGTTATTAGAAAAATCGACAGAGAATGAACCTCATTACTGGAATAGCGATTCTGAAGGGCTCTAG

Upstream 100 bases:

>100_bases
CTTGAGAGTATTATCTTACCAAGAGATACCAGACGAAAAGCAGATACGTATAGTACAAGCTGTTGGTAATTAAGCCGCCT
AATTAGAACGGACGATCGAA

Downstream 100 bases:

>100_bases
GCGGCGGATAAATATGAATGAGAATATGATACACGATCAAGCTAGCGGCCTCCGTCGCTTAACCCAGCCTTCACTCACAA
AAGTTATCGCTGTAACGGGT

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKIKRFFAKDMRTALLQVKEELGSEAVIMSNKKVAGGVEIVAAIDGDSSPSTASPRLNKPQQPTQSQYTQMSEPKLPTGR
RQLDDDKVSIQPNAEGGRSMTKRFANMLKQYSHGADDEQQHRAENEDSLSALLNRQSSNGHQPQSSQHSSGTLDSAFARE
TGLSKLIAEDRRVERPAPRLDPTRYDRGRENAQSKGSDTEMETMRDEMTSIRRLLEHQVSGLMWQEVERREPLRAMLIKR
LERMGVSAELADQMACYIPEDTKPARAWKALLALVADQISVTQKDILKRGGIVALLGPTGVGKTTTVAKLAARAAMEYGA
DNVALVTTDTYRIGAHEQLSIYGRIMGCPVRVAKDSSELADVIYQLRNRRLILVDTAGMGQRDVRLSEQLDTLMQESGSV
INSYLVLPATAQRKVLQETIEHFRRIPLSGCILTKLDESLSLGEFISVVIQNALPVAYIANGQRVPEDIVIAQPKYMIAK
ANELLEKSTENEPHYWNSDSEGL

Sequences:

>Translated_503_residues
MKIKRFFAKDMRTALLQVKEELGSEAVIMSNKKVAGGVEIVAAIDGDSSPSTASPRLNKPQQPTQSQYTQMSEPKLPTGR
RQLDDDKVSIQPNAEGGRSMTKRFANMLKQYSHGADDEQQHRAENEDSLSALLNRQSSNGHQPQSSQHSSGTLDSAFARE
TGLSKLIAEDRRVERPAPRLDPTRYDRGRENAQSKGSDTEMETMRDEMTSIRRLLEHQVSGLMWQEVERREPLRAMLIKR
LERMGVSAELADQMACYIPEDTKPARAWKALLALVADQISVTQKDILKRGGIVALLGPTGVGKTTTVAKLAARAAMEYGA
DNVALVTTDTYRIGAHEQLSIYGRIMGCPVRVAKDSSELADVIYQLRNRRLILVDTAGMGQRDVRLSEQLDTLMQESGSV
INSYLVLPATAQRKVLQETIEHFRRIPLSGCILTKLDESLSLGEFISVVIQNALPVAYIANGQRVPEDIVIAQPKYMIAK
ANELLEKSTENEPHYWNSDSEGL
>Mature_503_residues
MKIKRFFAKDMRTALLQVKEELGSEAVIMSNKKVAGGVEIVAAIDGDSSPSTASPRLNKPQQPTQSQYTQMSEPKLPTGR
RQLDDDKVSIQPNAEGGRSMTKRFANMLKQYSHGADDEQQHRAENEDSLSALLNRQSSNGHQPQSSQHSSGTLDSAFARE
TGLSKLIAEDRRVERPAPRLDPTRYDRGRENAQSKGSDTEMETMRDEMTSIRRLLEHQVSGLMWQEVERREPLRAMLIKR
LERMGVSAELADQMACYIPEDTKPARAWKALLALVADQISVTQKDILKRGGIVALLGPTGVGKTTTVAKLAARAAMEYGA
DNVALVTTDTYRIGAHEQLSIYGRIMGCPVRVAKDSSELADVIYQLRNRRLILVDTAGMGQRDVRLSEQLDTLMQESGSV
INSYLVLPATAQRKVLQETIEHFRRIPLSGCILTKLDESLSLGEFISVVIQNALPVAYIANGQRVPEDIVIAQPKYMIAK
ANELLEKSTENEPHYWNSDSEGL

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Escherichia coli, GI1789874, Length=190, Percent_Identity=32.6315789473684, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 55857; Mature: 55857

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKRFFAKDMRTALLQVKEELGSEAVIMSNKKVAGGVEIVAAIDGDSSPSTASPRLNKP
CCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
QQPTQSQYTQMSEPKLPTGRRQLDDDKVSIQPNAEGGRSMTKRFANMLKQYSHGADDEQQ
CCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHH
HRAENEDSLSALLNRQSSNGHQPQSSQHSSGTLDSAFARETGLSKLIAEDRRVERPAPRL
HHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPTRYDRGRENAQSKGSDTEMETMRDEMTSIRRLLEHQVSGLMWQEVERREPLRAMLIKR
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LERMGVSAELADQMACYIPEDTKPARAWKALLALVADQISVTQKDILKRGGIVALLGPTG
HHHCCCCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
VGKTTTVAKLAARAAMEYGADNVALVTTDTYRIGAHEQLSIYGRIMGCPVRVAKDSSELA
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCEECCCCCHHHHHHHHHCCCEEECCCHHHHH
DVIYQLRNRRLILVDTAGMGQRDVRLSEQLDTLMQESGSVINSYLVLPATAQRKVLQETI
HHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHH
EHFRRIPLSGCILTKLDESLSLGEFISVVIQNALPVAYIANGQRVPEDIVIAQPKYMIAK
HHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCCHHEEECCHHHHHH
ANELLEKSTENEPHYWNSDSEGL
HHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIKRFFAKDMRTALLQVKEELGSEAVIMSNKKVAGGVEIVAAIDGDSSPSTASPRLNKP
CCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
QQPTQSQYTQMSEPKLPTGRRQLDDDKVSIQPNAEGGRSMTKRFANMLKQYSHGADDEQQ
CCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHH
HRAENEDSLSALLNRQSSNGHQPQSSQHSSGTLDSAFARETGLSKLIAEDRRVERPAPRL
HHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPTRYDRGRENAQSKGSDTEMETMRDEMTSIRRLLEHQVSGLMWQEVERREPLRAMLIKR
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LERMGVSAELADQMACYIPEDTKPARAWKALLALVADQISVTQKDILKRGGIVALLGPTG
HHHCCCCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
VGKTTTVAKLAARAAMEYGADNVALVTTDTYRIGAHEQLSIYGRIMGCPVRVAKDSSELA
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCEECCCCCHHHHHHHHHCCCEEECCCHHHHH
DVIYQLRNRRLILVDTAGMGQRDVRLSEQLDTLMQESGSVINSYLVLPATAQRKVLQETI
HHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHH
EHFRRIPLSGCILTKLDESLSLGEFISVVIQNALPVAYIANGQRVPEDIVIAQPKYMIAK
HHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCCHHEEECCHHHHHH
ANELLEKSTENEPHYWNSDSEGL
HHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9503621 [H]