Click here to switch to the map view.

The map label for this gene is engA

Identifier: 218708645

GI number: 218708645

Start: 645232

End: 646713

Strand: Direct

Name: engA

Synonym: VS_0623

Alternate gene names: 218708645

Gene position: 645232-646713 (Clockwise)

Preceding gene: 218708644

Following gene: 218708646

Centisome position: 19.56

GC content: 43.66

Gene sequence:

>1482_bases
ATGGTACCTGTTGTTGCTCTAGTAGGGCGTCCGAACGTAGGTAAATCTACGTTATTTAACCGATTGACTCGAACTCGTGA
TGCATTGGTTGCGGATTTCCCTGGCTTAACGCGTGACCGTAAATACGGTCATGCTCATTTTAGCGAGCATGACTTTATTG
TTATCGACACTGGTGGTATCGACGGTACCGAAGAAGGTGTTGAAACTAAAATGGCTGAACAGTCGCTAGCGGCGATTGAT
GAAGCTGATGTCGTTCTATTTATGGTAGATGGCCGTGCGGGTCTAACACCTTCAGACGTAGCTATTGCTAAGCACCTTCG
TCAACTAGAAAAGCCTTCAATGCTAGTAGTAAACAAGGTTGATGGTATCGACCCTGATGCTGCAAGTGCTGATTTCTGGC
AACTAGGCGTAGAAGACATGTACCAAATCGCTGCAGCGCACGGTCGTGGTGTAACAGCGTTGATTGATCTTGCTCTAAAC
CCATTCGCTGAAGCGTTAAAAGCTGAGAATGGCGAAGTAAGCGATTTAACTGAATTTGAAGACGAAGAAGAAGAGCAAGT
TGATTTCACTGAAGAAGAAGCGGAAGAAGAATTCAAGCGCCTTCAAGATCAACCGATTAAGCTAGCGATCATTGGTCGTC
CTAACGTAGGTAAATCAACACTAACTAACCGTATTCTTGGTGAAGAACGTGTTGTTGTTTACGATATGCCAGGTACAACT
CGTGACTCTATCTACATTCCGATGCAGCGTGATGAGCGTGAATACGTTCTGATTGATACTGCGGGTGTTCGTCGCCGTAA
AAATATCAATGAAACAGTTGAGAAGTTCTCAGTGGTTAAAACACTGAAAGCGATTGAAGATGCTAACGTTGTATTACTGC
TTATCGATGCTCGCGAGAACATCTCAGATCAAGATCTAAGCTTGTTAGGCTTTGCGTTGAATGCTGGTCGTTCAATTGTT
ATTGCCGTAAACAAGTGGGATGGCCTAGATAACGACGTTAAAGATCGTGTTAAGAAAGAACTAGATCGTCGTTTAGGTTT
CGTTGATTTCGCACGTATTCACTTTATCTCTGCACTTCACGGTACTGGTGTTGGTCACTTGTTTGAGTCTGTTCAAGAAG
CTTATAAGTCAGCAACGACTCGTGTTGGTACTTCTGTACTTACTCGTATCATGAAGATGGCGACTGATGATCACCAACCA
CCTATGGTTCGTGGTCGTCGTGTTAAATTGAAATACGCGCACGCTGGTGGCTACAACCCACCGATTATCGTTATCCACGG
TAACCAAGTACGTAACTTGCCAGATTCATACAAACGATTCTTGATGAACTACTACCGTCGTTCACTAGAAATTATGGGTA
CACCTATTCGCATTCAATTCCAGAACAGCGAGAACCCATTTGAAGCTAAGACTAACAAGCTGACAATTTCTCAAGAACGT
AAACGTAAACGTATGATGAGCATGGTTAAAGGTCGCAAGTAA

Upstream 100 bases:

>100_bases
GTTATAAATTAATAAACCGTGTGGTTATAGGTAAGAGTTTAAACTTGCGATCAAGTGCTTACCTATAACTACATTTAGAG
AAGAAATTGTAGAGGTTGTT

Downstream 100 bases:

>100_bases
ACCTTTCCAATAGATTTGATACCCGAGCCTGTCTCGGGTATTTTTTTAAGTAAAATTCACGTTATCTGATAATCGCGTCT
TTGATTCCGTTATCAGCTAG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHFSEHDFIVIDTGGIDGTEEGVETKMAEQSLAAID
EADVVLFMVDGRAGLTPSDVAIAKHLRQLEKPSMLVVNKVDGIDPDAASADFWQLGVEDMYQIAAAHGRGVTALIDLALN
PFAEALKAENGEVSDLTEFEDEEEEQVDFTEEEAEEEFKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPGTT
RDSIYIPMQRDEREYVLIDTAGVRRRKNINETVEKFSVVKTLKAIEDANVVLLLIDARENISDQDLSLLGFALNAGRSIV
IAVNKWDGLDNDVKDRVKKELDRRLGFVDFARIHFISALHGTGVGHLFESVQEAYKSATTRVGTSVLTRIMKMATDDHQP
PMVRGRRVKLKYAHAGGYNPPIIVIHGNQVRNLPDSYKRFLMNYYRRSLEIMGTPIRIQFQNSENPFEAKTNKLTISQER
KRKRMMSMVKGRK

Sequences:

>Translated_493_residues
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHFSEHDFIVIDTGGIDGTEEGVETKMAEQSLAAID
EADVVLFMVDGRAGLTPSDVAIAKHLRQLEKPSMLVVNKVDGIDPDAASADFWQLGVEDMYQIAAAHGRGVTALIDLALN
PFAEALKAENGEVSDLTEFEDEEEEQVDFTEEEAEEEFKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPGTT
RDSIYIPMQRDEREYVLIDTAGVRRRKNINETVEKFSVVKTLKAIEDANVVLLLIDARENISDQDLSLLGFALNAGRSIV
IAVNKWDGLDNDVKDRVKKELDRRLGFVDFARIHFISALHGTGVGHLFESVQEAYKSATTRVGTSVLTRIMKMATDDHQP
PMVRGRRVKLKYAHAGGYNPPIIVIHGNQVRNLPDSYKRFLMNYYRRSLEIMGTPIRIQFQNSENPFEAKTNKLTISQER
KRKRMMSMVKGRK
>Mature_493_residues
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHFSEHDFIVIDTGGIDGTEEGVETKMAEQSLAAID
EADVVLFMVDGRAGLTPSDVAIAKHLRQLEKPSMLVVNKVDGIDPDAASADFWQLGVEDMYQIAAAHGRGVTALIDLALN
PFAEALKAENGEVSDLTEFEDEEEEQVDFTEEEAEEEFKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPGTT
RDSIYIPMQRDEREYVLIDTAGVRRRKNINETVEKFSVVKTLKAIEDANVVLLLIDARENISDQDLSLLGFALNAGRSIV
IAVNKWDGLDNDVKDRVKKELDRRLGFVDFARIHFISALHGTGVGHLFESVQEAYKSATTRVGTSVLTRIMKMATDDHQP
PMVRGRRVKLKYAHAGGYNPPIIVIHGNQVRNLPDSYKRFLMNYYRRSLEIMGTPIRIQFQNSENPFEAKTNKLTISQER
KRKRMMSMVKGRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=498, Percent_Identity=70.8835341365462, Blast_Score=715, Evalue=0.0,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=33.8709677419355, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367268, Length=165, Percent_Identity=31.5151515151515, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=198, Percent_Identity=26.7676767676768, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_VIBSL (B7VJU2)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416266.1
- GeneID:   7160243
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0623
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 55365; Mature: 55365

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHFSEHDFIVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCC
DGTEEGVETKMAEQSLAAIDEADVVLFMVDGRAGLTPSDVAIAKHLRQLEKPSMLVVNKV
CCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECC
DGIDPDAASADFWQLGVEDMYQIAAAHGRGVTALIDLALNPFAEALKAENGEVSDLTEFE
CCCCCCCCCCHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCC
DEEEEQVDFTEEEAEEEFKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPGTT
CCCHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCC
RDSIYIPMQRDEREYVLIDTAGVRRRKNINETVEKFSVVKTLKAIEDANVVLLLIDAREN
CCCEEEECCCCCCCEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
ISDQDLSLLGFALNAGRSIVIAVNKWDGLDNDVKDRVKKELDRRLGFVDFARIHFISALH
CCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GTGVGHLFESVQEAYKSATTRVGTSVLTRIMKMATDDHQPPMVRGRRVKLKYAHAGGYNP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCC
PIIVIHGNQVRNLPDSYKRFLMNYYRRSLEIMGTPIRIQFQNSENPFEAKTNKLTISQER
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEHHHH
KRKRMMSMVKGRK
HHHHHHHHHCCCC
>Mature Secondary Structure
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHFSEHDFIVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCC
DGTEEGVETKMAEQSLAAIDEADVVLFMVDGRAGLTPSDVAIAKHLRQLEKPSMLVVNKV
CCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECC
DGIDPDAASADFWQLGVEDMYQIAAAHGRGVTALIDLALNPFAEALKAENGEVSDLTEFE
CCCCCCCCCCHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCC
DEEEEQVDFTEEEAEEEFKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPGTT
CCCHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCC
RDSIYIPMQRDEREYVLIDTAGVRRRKNINETVEKFSVVKTLKAIEDANVVLLLIDAREN
CCCEEEECCCCCCCEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
ISDQDLSLLGFALNAGRSIVIAVNKWDGLDNDVKDRVKKELDRRLGFVDFARIHFISALH
CCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GTGVGHLFESVQEAYKSATTRVGTSVLTRIMKMATDDHQPPMVRGRRVKLKYAHAGGYNP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCC
PIIVIHGNQVRNLPDSYKRFLMNYYRRSLEIMGTPIRIQFQNSENPFEAKTNKLTISQER
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEHHHH
KRKRMMSMVKGRK
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA