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The map label for this gene is estR [H]

Identifier: 218708616

GI number: 218708616

Start: 618140

End: 619045

Strand: Direct

Name: estR [H]

Synonym: VS_0594

Alternate gene names: 218708616

Gene position: 618140-619045 (Clockwise)

Preceding gene: 218708612

Following gene: 218708620

Centisome position: 18.74

GC content: 45.7

Gene sequence:

>906_bases
ATGAATAAATGGCCAAGTCTTAAGCAACTTCACTATCTTGTTACTCTTCACGAAACTCGCCACTTTAGCGACGCTGCGGA
TCGCTGCTTCGTGAGTCAATCGACACTAAGTAAAGGCATTCAAAACCTGGAAGAACTCATTGGTTGTCCTCTCTATGAGA
AGAAAGATAAAAAGAGCCCATTGGTTTTCACTCAAGCGGGTGAGCTGGTGGTTAAGCATGGTCGAGAGTTATTGGCGAAA
GGGCAAGACTTGGTTGAGCTCGGAAATCTATGTAATGGAGACGCGATGCAAGGGCAGTTGCGAGTAGGGTGTATTCCTAC
TATTGCTCCATTCCTATTGTGCGATTTGGTACAAGAAGCGAACCAACGTTTTCCACAATTGAACTTGTTATTACGGGAAG
ACACGACAACTAACCTTTTGGCTGCGTTGCGTCATGGTGAGTTGGATGTACTGATTCTGGCTTTGCCTGTCGATATCGAC
AACATGGAGAGCAAAGTTGTTGGGCAAGACCCTTTCAGAATGGTAATCAGCCGCAATCAAGCCGATGGTATTCGTGTTCC
GATTAAATATGATGACCTGCCAGACGAATCTGTATTCTTGTTGGAGAACGAGCACTGTTTAACCGAGCACGCGGTATCAG
CTTGTAAGCTAACCGACAAAGAGAAGATAAACCCGTTCACCGCCACAAGCCTACATACGTTGGTACAAATGGTGGCAAAT
GGTTTAGGAACCACCTTTATCCCACAAATGGCGATCGATCATGGTTTGTTGCAAAATCAGAATTTAGTGGTGATCGACCC
GCCAGGCCAACAAGCATACCGAGACATAGGCCTTGTATGGCGACCAAGCTCGTCACGTCTTGAAACCTTTCATCAGTTAG
CTGATGTGGTCTCTGAATTGCTTTAA

Upstream 100 bases:

>100_bases
ATTAAGTTAATCGAAAAAAGCGATAAGCTTATTCTTTGTCCGTTCCTTAGGTCAAATGACCTTCACTTAAGTTATCCAAC
TCATATTACAAAGTAATTTC

Downstream 100 bases:

>100_bases
AAAACTAGAAAGTAAAATTCAAAACAAAAAGAGCAGCGATTTGGCTGCTCTTTTTGTTTGTTCATTTGAGAAGAAAAACG
CCACAAATATAGTGGCGTTA

Product: transcriptional regulator

Products: NA

Alternate protein names: Esterase operon transcriptional regulator [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNKWPSLKQLHYLVTLHETRHFSDAADRCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSPLVFTQAGELVVKHGRELLAK
GQDLVELGNLCNGDAMQGQLRVGCIPTIAPFLLCDLVQEANQRFPQLNLLLREDTTTNLLAALRHGELDVLILALPVDID
NMESKVVGQDPFRMVISRNQADGIRVPIKYDDLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTATSLHTLVQMVAN
GLGTTFIPQMAIDHGLLQNQNLVVIDPPGQQAYRDIGLVWRPSSSRLETFHQLADVVSELL

Sequences:

>Translated_301_residues
MNKWPSLKQLHYLVTLHETRHFSDAADRCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSPLVFTQAGELVVKHGRELLAK
GQDLVELGNLCNGDAMQGQLRVGCIPTIAPFLLCDLVQEANQRFPQLNLLLREDTTTNLLAALRHGELDVLILALPVDID
NMESKVVGQDPFRMVISRNQADGIRVPIKYDDLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTATSLHTLVQMVAN
GLGTTFIPQMAIDHGLLQNQNLVVIDPPGQQAYRDIGLVWRPSSSRLETFHQLADVVSELL
>Mature_301_residues
MNKWPSLKQLHYLVTLHETRHFSDAADRCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSPLVFTQAGELVVKHGRELLAK
GQDLVELGNLCNGDAMQGQLRVGCIPTIAPFLLCDLVQEANQRFPQLNLLLREDTTTNLLAALRHGELDVLILALPVDID
NMESKVVGQDPFRMVISRNQADGIRVPIKYDDLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTATSLHTLVQMVAN
GLGTTFIPQMAIDHGLLQNQNLVVIDPPGQQAYRDIGLVWRPSSSRLETFHQLADVVSELL

Specific function: Transcriptional regulator of the esterase operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=36.3013698630137, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1788748, Length=304, Percent_Identity=25.9868421052632, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=269, Percent_Identity=24.5353159851301, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693105, Length=255, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33578; Mature: 33578

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKWPSLKQLHYLVTLHETRHFSDAADRCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSP
CCCCCCHHHHHHHEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LVFTQAGELVVKHGRELLAKGQDLVELGNLCNGDAMQGQLRVGCIPTIAPFLLCDLVQEA
EEEECCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
NQRFPQLNLLLREDTTTNLLAALRHGELDVLILALPVDIDNMESKVVGQDPFRMVISRNQ
HHCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHCCCC
ADGIRVPIKYDDLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTATSLHTLVQMVAN
CCCEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHH
GLGTTFIPQMAIDHGLLQNQNLVVIDPPGQQAYRDIGLVWRPSSSRLETFHQLADVVSEL
CCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHHHH
L
C
>Mature Secondary Structure
MNKWPSLKQLHYLVTLHETRHFSDAADRCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSP
CCCCCCHHHHHHHEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LVFTQAGELVVKHGRELLAKGQDLVELGNLCNGDAMQGQLRVGCIPTIAPFLLCDLVQEA
EEEECCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
NQRFPQLNLLLREDTTTNLLAALRHGELDVLILALPVDIDNMESKVVGQDPFRMVISRNQ
HHCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHCCCC
ADGIRVPIKYDDLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTATSLHTLVQMVAN
CCCEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHH
GLGTTFIPQMAIDHGLLQNQNLVVIDPPGQQAYRDIGLVWRPSSSRLETFHQLADVVSEL
CCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHHHH
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA