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The map label for this gene is nagZ [H]

Identifier: 218708580

GI number: 218708580

Start: 568437

End: 569414

Strand: Direct

Name: nagZ [H]

Synonym: VS_0546

Alternate gene names: 218708580

Gene position: 568437-569414 (Clockwise)

Preceding gene: 218708577

Following gene: 218708581

Centisome position: 17.23

GC content: 47.03

Gene sequence:

>978_bases
ATGGGACCGTTGTGGGTAGATGTCGCGGGCTACGAACTGACAGCTGAAGACAGAGAAATTTTAGATCACCCAACCGTTGG
TGGTCTCATCTTATTCGCTCGAAACTACCACGATAGCAAACAGCTTTCGGCGTTAAATAAAGAGATCCGCAAGGTAGCGA
AACGTCCTATTTTGATTGGCGTTGACCAAGAAGGTGGCCGAGTTCAGCGCTTTCGTGATGGCTTTTCAATTATCCCTGCA
GCTCAAGAATTTGCGACTAAGAACGATGGTGAGCAGTTAGCAGAACAAGCCGGCTGGTTGATGGCGGCGGAATTGATTGC
CCATGATATCGATCTGAGCTTTGCGCCGGTATTAGACAAAGGCCACGACTGTAAAGCGATTGGTAGCCGAGCGTTTGGTG
AAGATATTGATACCATTGTTCGTCACAGCAGCGCTTTTATTAAAGGCATGAAATCGGTTGGAATGGCGACAACAGGGAAG
CACTTCCCAGGACACGGCGGTGTAATTGCTGATTCGCACTTAGAAACGCCTTACGATCCTAGAGATGATATCTTTGAAAC
AGACATGGCCATTTTCAAGGCGCAAATTGAAGCCGGAATATTGGATGCCATGATGCCTGCACACGTTGTTTTCTCTCACT
ATGATGATCAGCCAGCGAGTGGCTCACAGTATTGGTTGCAGAAAGTATTGAAGCAGCAGCTTGGATTCAAAGGCTTAGTT
TTTTCTGACGACTTAACGATGGAAGGCGCTGCCATTATGGGCGGACCAGCAGATAGAGCGAAAGCAGCCTTGAGTGCTGG
CTGTGACATGGTGCTGATGTGTAATAAGCGAGATGCACAAATTGAGGCTCTTGATCATTTAGCGATTCAAGAGGTGCCTT
TAGCCAACTCATTGCTTAAAAAGCACAGCTTTGATTTATCGACGCTTCACTCGGATAGTCGATGGAAAGAGGCCTCAGAG
CAAATTAAGCGAATGTAA

Upstream 100 bases:

>100_bases
TCTTAAAGTCTTCCACAGATTGGTTTAAAAACATTGTAAAGCAAATTTAAAGAGAATAATCTCGGGAAGTTTATGAAATT
AGGTTTAATAAGGGATAAAT

Downstream 100 bases:

>100_bases
ACGCTGGGTGATAAATAAACACTCTATAAGTTTGAAGAAGGCGATATGAGAAATATCGCCTTTTTTGTATGTGTGAGGTG
CAGTTTAAGCTGGTTTGTGT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MGPLWVDVAGYELTAEDREILDHPTVGGLILFARNYHDSKQLSALNKEIRKVAKRPILIGVDQEGGRVQRFRDGFSIIPA
AQEFATKNDGEQLAEQAGWLMAAELIAHDIDLSFAPVLDKGHDCKAIGSRAFGEDIDTIVRHSSAFIKGMKSVGMATTGK
HFPGHGGVIADSHLETPYDPRDDIFETDMAIFKAQIEAGILDAMMPAHVVFSHYDDQPASGSQYWLQKVLKQQLGFKGLV
FSDDLTMEGAAIMGGPADRAKAALSAGCDMVLMCNKRDAQIEALDHLAIQEVPLANSLLKKHSFDLSTLHSDSRWKEASE
QIKRM

Sequences:

>Translated_325_residues
MGPLWVDVAGYELTAEDREILDHPTVGGLILFARNYHDSKQLSALNKEIRKVAKRPILIGVDQEGGRVQRFRDGFSIIPA
AQEFATKNDGEQLAEQAGWLMAAELIAHDIDLSFAPVLDKGHDCKAIGSRAFGEDIDTIVRHSSAFIKGMKSVGMATTGK
HFPGHGGVIADSHLETPYDPRDDIFETDMAIFKAQIEAGILDAMMPAHVVFSHYDDQPASGSQYWLQKVLKQQLGFKGLV
FSDDLTMEGAAIMGGPADRAKAALSAGCDMVLMCNKRDAQIEALDHLAIQEVPLANSLLKKHSFDLSTLHSDSRWKEASE
QIKRM
>Mature_324_residues
GPLWVDVAGYELTAEDREILDHPTVGGLILFARNYHDSKQLSALNKEIRKVAKRPILIGVDQEGGRVQRFRDGFSIIPAA
QEFATKNDGEQLAEQAGWLMAAELIAHDIDLSFAPVLDKGHDCKAIGSRAFGEDIDTIVRHSSAFIKGMKSVGMATTGKH
FPGHGGVIADSHLETPYDPRDDIFETDMAIFKAQIEAGILDAMMPAHVVFSHYDDQPASGSQYWLQKVLKQQLGFKGLVF
SDDLTMEGAAIMGGPADRAKAALSAGCDMVLMCNKRDAQIEALDHLAIQEVPLANSLLKKHSFDLSTLHSDSRWKEASEQ
IKRM

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=330, Percent_Identity=54.2424242424242, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 35656; Mature: 35525

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPLWVDVAGYELTAEDREILDHPTVGGLILFARNYHDSKQLSALNKEIRKVAKRPILIG
CCCEEEEECCCEECCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEE
VDQEGGRVQRFRDGFSIIPAAQEFATKNDGEQLAEQAGWLMAAELIAHDIDLSFAPVLDK
ECCCCCHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
GHDCKAIGSRAFGEDIDTIVRHSSAFIKGMKSVGMATTGKHFPGHGGVIADSHLETPYDP
CCCCHHHHCHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCC
RDDIFETDMAIFKAQIEAGILDAMMPAHVVFSHYDDQPASGSQYWLQKVLKQQLGFKGLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEE
FSDDLTMEGAAIMGGPADRAKAALSAGCDMVLMCNKRDAQIEALDHLAIQEVPLANSLLK
EECCCCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHH
KHSFDLSTLHSDSRWKEASEQIKRM
HHCCCHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
GPLWVDVAGYELTAEDREILDHPTVGGLILFARNYHDSKQLSALNKEIRKVAKRPILIG
CCEEEEECCCEECCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEE
VDQEGGRVQRFRDGFSIIPAAQEFATKNDGEQLAEQAGWLMAAELIAHDIDLSFAPVLDK
ECCCCCHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
GHDCKAIGSRAFGEDIDTIVRHSSAFIKGMKSVGMATTGKHFPGHGGVIADSHLETPYDP
CCCCHHHHCHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCC
RDDIFETDMAIFKAQIEAGILDAMMPAHVVFSHYDDQPASGSQYWLQKVLKQQLGFKGLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEE
FSDDLTMEGAAIMGGPADRAKAALSAGCDMVLMCNKRDAQIEALDHLAIQEVPLANSLLK
EECCCCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHH
KHSFDLSTLHSDSRWKEASEQIKRM
HHCCCHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA