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The map label for this gene is ftsZ [H]

Identifier: 218708490

GI number: 218708490

Start: 465934

End: 467163

Strand: Direct

Name: ftsZ [H]

Synonym: VS_0454

Alternate gene names: 218708490

Gene position: 465934-467163 (Clockwise)

Preceding gene: 218708489

Following gene: 218708491

Centisome position: 14.12

GC content: 46.18

Gene sequence:

>1230_bases
ATGTTTGAACCGATGATGGAAATGTCTGACGATGCAGTAATTAAAGTCGTTGGAGTTGGTGGCGGTGGCGGTAACGCTGT
TGAGCACATGGTGCGTGAATCAATCGAAGGTGTAGAATTCATCAGTGTTAACACTGATGCACAAGCACTTCGTAAAACAA
GCGTTAGCAGCGTGATCCAAATTGGTGGTGATATCACTAAAGGTTTGGGCGCTGGTGCAAACCCACAAGTAGGCCGTGAT
GCAGCTCTCGAAGATCGAGAAAGAATTAAAGAAGTTCTAACTGGCGCCGATATGGTATTTATCGCAGCTGGTATGGGCGG
TGGTACAGGTACAGGTGCTGCTCCAGTTATTGCTGAAGTTGCGAAAGAGCTGGGTGTGCTAACGGTTGCTGTTGTAACTA
AGCCATTTAGCTTCGAAGGCAAAAAGCGTTTAGCGTTTGCTGAGCAAGGTATCGAAGAGCTTTCTAAGCATGTGGATTCT
TTAATTACGATTCCAAATGAAAAGCTACTTAAGGTACTTGGCCGCGGCGTCACTCTGCTAGAAGCTTTCGCAAGTGCAAA
TGATGTACTTAAAAATGCTGTACAAGGTATCGCTGAGCTAATTACTCGCCCAGGTATGATTAACGTCGATTTCGCGGATG
TTCGCACCGTAATGTCAGAGATGGGTCATGCAATGATGGGTAGCGGTATCGCAAAAGGCGAAGACCGTGCTGAAGAAGCT
GCTGAAACGGCAATTTCTAGCCCACTACTAGAAGACATCGACCTAGCTGGTGCTCGTGGCGTTCTTGTGAACATCACAGC
TGGCCTAGATATGCGCTTAGATGAATTCGAAACAGTAGGTAATACAGTTAAGGCATTCGCATCTGATAACGCAACGGTTG
TTATTGGTACATCTCTAGACCCTGATATGACGGATGAAATCCGTGTAACTGTTGTAGCAACAGGTATCGGCACAGAGAAA
AAACCAGACATTACACTAGTTGCTGGTGGTAAAGCTAAGGTTGCACCAACTCCTCAACCACAGGTAGCGGCTCAAACTGC
ACCAAAAGTGGAAGATAAAGTGGCACAACCATTGCAAGAAAAAACTGAGGTGAAACCTCAAGTTAAGCCGCAGCCAACAA
CGTCACCTGTTTCTTCAGGTACAGGCGCTAGCCAAAGTGCAGCACCTAAAGCTGAGAAAGAGAGTGGATACTTAGATATT
CCGGCATTCTTACGACGTCAGGCTGATTAA

Upstream 100 bases:

>100_bases
AAGCGTTCAGCACCTTCTATGTCTGGTTTATTTGGTAAATTGCGTAATTGGATACAAAAAGAGTTTTAACCTGAGTTGCA
GGAAAAAACGGAGATAACAC

Downstream 100 bases:

>100_bases
CAAATACCCAAAGTTTGACTATCGTCGAATTAATGGTAAAATTCGCGGTCGGTAAATACTGACCGTGATTTGTAGCACTG
ATAACGAGGCAAGCAGATGA

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MFEPMMEMSDDAVIKVVGVGGGGGNAVEHMVRESIEGVEFISVNTDAQALRKTSVSSVIQIGGDITKGLGAGANPQVGRD
AALEDRERIKEVLTGADMVFIAAGMGGGTGTGAAPVIAEVAKELGVLTVAVVTKPFSFEGKKRLAFAEQGIEELSKHVDS
LITIPNEKLLKVLGRGVTLLEAFASANDVLKNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAKGEDRAEEA
AETAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLDPDMTDEIRVTVVATGIGTEK
KPDITLVAGGKAKVAPTPQPQVAAQTAPKVEDKVAQPLQEKTEVKPQVKPQPTTSPVSSGTGASQSAAPKAEKESGYLDI
PAFLRRQAD

Sequences:

>Translated_409_residues
MFEPMMEMSDDAVIKVVGVGGGGGNAVEHMVRESIEGVEFISVNTDAQALRKTSVSSVIQIGGDITKGLGAGANPQVGRD
AALEDRERIKEVLTGADMVFIAAGMGGGTGTGAAPVIAEVAKELGVLTVAVVTKPFSFEGKKRLAFAEQGIEELSKHVDS
LITIPNEKLLKVLGRGVTLLEAFASANDVLKNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAKGEDRAEEA
AETAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLDPDMTDEIRVTVVATGIGTEK
KPDITLVAGGKAKVAPTPQPQVAAQTAPKVEDKVAQPLQEKTEVKPQVKPQPTTSPVSSGTGASQSAAPKAEKESGYLDI
PAFLRRQAD
>Mature_409_residues
MFEPMMEMSDDAVIKVVGVGGGGGNAVEHMVRESIEGVEFISVNTDAQALRKTSVSSVIQIGGDITKGLGAGANPQVGRD
AALEDRERIKEVLTGADMVFIAAGMGGGTGTGAAPVIAEVAKELGVLTVAVVTKPFSFEGKKRLAFAEQGIEELSKHVDS
LITIPNEKLLKVLGRGVTLLEAFASANDVLKNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAKGEDRAEEA
AETAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLDPDMTDEIRVTVVATGIGTEK
KPDITLVAGGKAKVAPTPQPQVAAQTAPKVEDKVAQPLQEKTEVKPQVKPQPTTSPVSSGTGASQSAAPKAEKESGYLDI
PAFLRRQAD

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=409, Percent_Identity=72.1271393643032, Blast_Score=518, Evalue=1e-148,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 42484; Mature: 42484

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEPMMEMSDDAVIKVVGVGGGGGNAVEHMVRESIEGVEFISVNTDAQALRKTSVSSVIQ
CCCCCHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
IGGDITKGLGAGANPQVGRDAALEDRERIKEVLTGADMVFIAAGMGGGTGTGAAPVIAEV
HCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AKELGVLTVAVVTKPFSFEGKKRLAFAEQGIEELSKHVDSLITIPNEKLLKVLGRGVTLL
HHHHCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHH
EAFASANDVLKNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAKGEDRAEEA
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCHHHHCCCCCCCHHHHHHH
AETAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLD
HHHHHHCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
PDMTDEIRVTVVATGIGTEKKPDITLVAGGKAKVAPTPQPQVAAQTAPKVEDKVAQPLQE
CCCCCCEEEEEEEECCCCCCCCCEEEEECCCEECCCCCCCCHHHHCCCCHHHHHHHHHHH
KTEVKPQVKPQPTTSPVSSGTGASQSAAPKAEKESGYLDIPAFLRRQAD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHCCCC
>Mature Secondary Structure
MFEPMMEMSDDAVIKVVGVGGGGGNAVEHMVRESIEGVEFISVNTDAQALRKTSVSSVIQ
CCCCCHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
IGGDITKGLGAGANPQVGRDAALEDRERIKEVLTGADMVFIAAGMGGGTGTGAAPVIAEV
HCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AKELGVLTVAVVTKPFSFEGKKRLAFAEQGIEELSKHVDSLITIPNEKLLKVLGRGVTLL
HHHHCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHH
EAFASANDVLKNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAKGEDRAEEA
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCHHHHCCCCCCCHHHHHHH
AETAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLD
HHHHHHCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
PDMTDEIRVTVVATGIGTEKKPDITLVAGGKAKVAPTPQPQVAAQTAPKVEDKVAQPLQE
CCCCCCEEEEEEEECCCCCCCCCEEEEECCCEECCCCCCCCHHHHCCCCHHHHHHHHHHH
KTEVKPQVKPQPTTSPVSSGTGASQSAAPKAEKESGYLDIPAFLRRQAD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11443086 [H]