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The map label for this gene is ftsA [H]

Identifier: 218708489

GI number: 218708489

Start: 464634

End: 465902

Strand: Direct

Name: ftsA [H]

Synonym: VS_0453

Alternate gene names: 218708489

Gene position: 464634-465902 (Clockwise)

Preceding gene: 218708488

Following gene: 218708490

Centisome position: 14.08

GC content: 44.21

Gene sequence:

>1269_bases
ATGACTAAGACCGCAGATGACAACATAATCGTTGGTCTTGATATAGGCACTGCGACCATATCAGCTCTAGTTGGTGAAAT
ATTGCCTGATGGTCAAATCAATATCATTGGTTCTGGGCAAAGCCCATCCAGAGGTATGGATAAAGGTGGTGTAAACGACC
TAGAGTCGGTAGTTAAGTCGGTTCAGCGAGCTATTGATCAAGCAGAGTTGATGGCGGAATGCCAAATCAGCAATGTATTT
ATCTCGCTATCGGGTAAACATATCGCAAGCCGAATTGAAAAAGGCATGGGCACTATCTCTGATGAAGAAGTGTCTCAAGA
CGATATGGATCGAGCGATCCATACCGCGAAATCAATTAAAATAGGTGATGAGCAGAGAATTCTGCACGTGATCCCTCAGG
AATTTACCATTGATTATCAAGAAGGGATTAAGAACCCACTTGGTTTATCTGGTGTTCGAATGGAAGTCAGTGTTCACCTA
ATTTCTTGCCATAGCGACATGGCGAGAAACATTATTAAAGCTGTTGAACGATGTGGTCTCACTGTAGAACAAATCGTGTT
TTCAGGACTTGCCTCAAGTAATGCGGTAATTACTGACGACGAGAGAGAGCTTGGAGTCTGTGTTGTTGATATTGGTGCTG
GTACGATGGATATCTCCATTTGGACTGGCGGCGCACTGCGACACACAGAAGTCTTTTCCTACGCAGGAAATGCAGTAACC
AGTGATATTGCCTTCGCTTTTGGCACGCCAGTGAGCGATGCTGAAGAGATAAAAGTAAACCATGGTTGCGCTCTGAGTGA
ACTCGTAAGCAAGGATGATTCTGTTAACGTCCCTAGTGTAGGTGGCCGTCCATCGAGAAGTTTGCAAAGACAAACTTTGT
CGGAAGTGATTGAACCACGTTACACTGAACTTATGGGGCTCGTTAACCAAACTATTGATACGGTTCAATTACAGCTACGA
GATGAAGGTATTAAACACCACCTTGCAGCTGGCGTCGTTCTCACTGGTGGAGCGGCACAAATTGACGGATTGGTAGAGTG
TGCGGAACGTGTTTTCCGCAATCAAGTTCGAGTTGGTAAGCCGTTAGAAGTTAGTGGTTTAACCGACTATGTTAAAGAGC
CGTATCATTCTACGGCGGTTGGTTTACTTCATTACGCAAGAGATTGTCAGGTCAGCGATGAAGGTGATTACAGCGAACCT
AAGCGTTCAGCACCTTCTATGTCTGGTTTATTTGGTAAATTGCGTAATTGGATACAAAAAGAGTTTTAA

Upstream 100 bases:

>100_bases
TTAGGTAGTAAGGCGAATCAAGTGAGCTACATCGACCTCAGGTACGATACGGGAGCCGCTGTAGGCTGGTTTCCAGAGCA
AGAGTTAGAAGAGAGTACAG

Downstream 100 bases:

>100_bases
CCTGAGTTGCAGGAAAAAACGGAGATAACACATGTTTGAACCGATGATGGAAATGTCTGACGATGCAGTAATTAAAGTCG
TTGGAGTTGGTGGCGGTGGC

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MTKTADDNIIVGLDIGTATISALVGEILPDGQINIIGSGQSPSRGMDKGGVNDLESVVKSVQRAIDQAELMAECQISNVF
ISLSGKHIASRIEKGMGTISDEEVSQDDMDRAIHTAKSIKIGDEQRILHVIPQEFTIDYQEGIKNPLGLSGVRMEVSVHL
ISCHSDMARNIIKAVERCGLTVEQIVFSGLASSNAVITDDERELGVCVVDIGAGTMDISIWTGGALRHTEVFSYAGNAVT
SDIAFAFGTPVSDAEEIKVNHGCALSELVSKDDSVNVPSVGGRPSRSLQRQTLSEVIEPRYTELMGLVNQTIDTVQLQLR
DEGIKHHLAAGVVLTGGAAQIDGLVECAERVFRNQVRVGKPLEVSGLTDYVKEPYHSTAVGLLHYARDCQVSDEGDYSEP
KRSAPSMSGLFGKLRNWIQKEF

Sequences:

>Translated_422_residues
MTKTADDNIIVGLDIGTATISALVGEILPDGQINIIGSGQSPSRGMDKGGVNDLESVVKSVQRAIDQAELMAECQISNVF
ISLSGKHIASRIEKGMGTISDEEVSQDDMDRAIHTAKSIKIGDEQRILHVIPQEFTIDYQEGIKNPLGLSGVRMEVSVHL
ISCHSDMARNIIKAVERCGLTVEQIVFSGLASSNAVITDDERELGVCVVDIGAGTMDISIWTGGALRHTEVFSYAGNAVT
SDIAFAFGTPVSDAEEIKVNHGCALSELVSKDDSVNVPSVGGRPSRSLQRQTLSEVIEPRYTELMGLVNQTIDTVQLQLR
DEGIKHHLAAGVVLTGGAAQIDGLVECAERVFRNQVRVGKPLEVSGLTDYVKEPYHSTAVGLLHYARDCQVSDEGDYSEP
KRSAPSMSGLFGKLRNWIQKEF
>Mature_421_residues
TKTADDNIIVGLDIGTATISALVGEILPDGQINIIGSGQSPSRGMDKGGVNDLESVVKSVQRAIDQAELMAECQISNVFI
SLSGKHIASRIEKGMGTISDEEVSQDDMDRAIHTAKSIKIGDEQRILHVIPQEFTIDYQEGIKNPLGLSGVRMEVSVHLI
SCHSDMARNIIKAVERCGLTVEQIVFSGLASSNAVITDDERELGVCVVDIGAGTMDISIWTGGALRHTEVFSYAGNAVTS
DIAFAFGTPVSDAEEIKVNHGCALSELVSKDDSVNVPSVGGRPSRSLQRQTLSEVIEPRYTELMGLVNQTIDTVQLQLRD
EGIKHHLAAGVVLTGGAAQIDGLVECAERVFRNQVRVGKPLEVSGLTDYVKEPYHSTAVGLLHYARDCQVSDEGDYSEPK
RSAPSMSGLFGKLRNWIQKEF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=422, Percent_Identity=67.2985781990521, Blast_Score=613, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45476; Mature: 45345

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTADDNIIVGLDIGTATISALVGEILPDGQINIIGSGQSPSRGMDKGGVNDLESVVKS
CCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
VQRAIDQAELMAECQISNVFISLSGKHIASRIEKGMGTISDEEVSQDDMDRAIHTAKSIK
HHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCE
IGDEQRILHVIPQEFTIDYQEGIKNPLGLSGVRMEVSVHLISCHSDMARNIIKAVERCGL
ECCCCHHHEECCHHHEEEHHHHCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHCC
TVEQIVFSGLASSNAVITDDERELGVCVVDIGAGTMDISIWTGGALRHTEVFSYAGNAVT
CHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHHCCCHHH
SDIAFAFGTPVSDAEEIKVNHGCALSELVSKDDSVNVPSVGGRPSRSLQRQTLSEVIEPR
HHHHHHCCCCCCCHHHEEECCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
YTELMGLVNQTIDTVQLQLRDEGIKHHLAAGVVLTGGAAQIDGLVECAERVFRNQVRVGK
HHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
PLEVSGLTDYVKEPYHSTAVGLLHYARDCQVSDEGDYSEPKRSAPSMSGLFGKLRNWIQK
CCEECCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHH
EF
CC
>Mature Secondary Structure 
TKTADDNIIVGLDIGTATISALVGEILPDGQINIIGSGQSPSRGMDKGGVNDLESVVKS
CCCCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
VQRAIDQAELMAECQISNVFISLSGKHIASRIEKGMGTISDEEVSQDDMDRAIHTAKSIK
HHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCE
IGDEQRILHVIPQEFTIDYQEGIKNPLGLSGVRMEVSVHLISCHSDMARNIIKAVERCGL
ECCCCHHHEECCHHHEEEHHHHCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHCC
TVEQIVFSGLASSNAVITDDERELGVCVVDIGAGTMDISIWTGGALRHTEVFSYAGNAVT
CHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHHCCCHHH
SDIAFAFGTPVSDAEEIKVNHGCALSELVSKDDSVNVPSVGGRPSRSLQRQTLSEVIEPR
HHHHHHCCCCCCCHHHEEECCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
YTELMGLVNQTIDTVQLQLRDEGIKHHLAAGVVLTGGAAQIDGLVECAERVFRNQVRVGK
HHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
PLEVSGLTDYVKEPYHSTAVGLLHYARDCQVSDEGDYSEPKRSAPSMSGLFGKLRNWIQK
CCEECCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHH
EF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]