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The map label for this gene is coaD

Identifier: 218708258

GI number: 218708258

Start: 190477

End: 190965

Strand: Direct

Name: coaD

Synonym: VS_0195

Alternate gene names: 218708258

Gene position: 190477-190965 (Clockwise)

Preceding gene: 218708257

Following gene: 218708259

Centisome position: 5.77

GC content: 39.26

Gene sequence:

>489_bases
ATGAAAATAGCAATATACCCAGGTACTTTTGATCCAGTGACTAACGGCCATTATGACTTAATTAAACGTGCCGCATGTAT
GTTTGAAAAACTTGTCATTGGTGTCGCAGAGAGCCCAAGTAAAGCCACCTTATTTAGCTTAGATGAGCGTGTGGCCTTAT
TGCGAGAAACTTGCTATGAATTACCTAATGTTTCCGTTGAAGGTTTTAGCGGTTTGTTGGTTGATTTTGCGACCGAGCAA
AACGCCTCAATTTTGGTGCGTGGCTTAAGAACAACAATGGACTTTGAGTATGAATTTGGTTTGACGACAATGTATCGTCG
ATTAAAACCAGAACTAGAGAGCCTGTTTTTGACACCTTCAGAAGAGTTTGCTTTTTTATCATCAACATTGGTTCGTGAAG
TCGCTATTCATGGTGGAGAAATAGAGCAATTTGTTCCAGGGTGTGTTCATCAAGCTGTTGTCGCTAAAGTAAAAGCTTTT
AAAAATTAA

Upstream 100 bases:

>100_bases
TCTTATGGCTCTTATTTCTACAGAATCGGTGATTGAGCAGCTAGACCGTGTATTAGGCCGATTGAAAAACAAGAAAACAT
CCAGTGAATAAAGGAATGTC

Downstream 100 bases:

>100_bases
GTGATTATGAATATTTTAATGTATACAAGAGCCACGTTACCTGTGGTGAATTATGGTGGAACCGAACGAGTCATTTGGGA
CTTAGTTTATGCTTTGCATT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MKIAIYPGTFDPVTNGHYDLIKRAACMFEKLVIGVAESPSKATLFSLDERVALLRETCYELPNVSVEGFSGLLVDFATEQ
NASILVRGLRTTMDFEYEFGLTTMYRRLKPELESLFLTPSEEFAFLSSTLVREVAIHGGEIEQFVPGCVHQAVVAKVKAF
KN

Sequences:

>Translated_162_residues
MKIAIYPGTFDPVTNGHYDLIKRAACMFEKLVIGVAESPSKATLFSLDERVALLRETCYELPNVSVEGFSGLLVDFATEQ
NASILVRGLRTTMDFEYEFGLTTMYRRLKPELESLFLTPSEEFAFLSSTLVREVAIHGGEIEQFVPGCVHQAVVAKVKAF
KN
>Mature_162_residues
MKIAIYPGTFDPVTNGHYDLIKRAACMFEKLVIGVAESPSKATLFSLDERVALLRETCYELPNVSVEGFSGLLVDFATEQ
NASILVRGLRTTMDFEYEFGLTTMYRRLKPELESLFLTPSEEFAFLSSTLVREVAIHGGEIEQFVPGCVHQAVVAKVKAF
KN

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=54.4871794871795, Blast_Score=189, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_VIBSL (B7VHL5)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002415879.1
- ProteinModelPortal:   B7VHL5
- GeneID:   7159862
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0195
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18076; Mature: 18076

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIYPGTFDPVTNGHYDLIKRAACMFEKLVIGVAESPSKATLFSLDERVALLRETCYE
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LPNVSVEGFSGLLVDFATEQNASILVRGLRTTMDFEYEFGLTTMYRRLKPELESLFLTPS
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEECCHHHHHHHHCHHHHHEECCCC
EEFAFLSSTLVREVAIHGGEIEQFVPGCVHQAVVAKVKAFKN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIAIYPGTFDPVTNGHYDLIKRAACMFEKLVIGVAESPSKATLFSLDERVALLRETCYE
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LPNVSVEGFSGLLVDFATEQNASILVRGLRTTMDFEYEFGLTTMYRRLKPELESLFLTPS
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEECCHHHHHHHHCHHHHHEECCCC
EEFAFLSSTLVREVAIHGGEIEQFVPGCVHQAVVAKVKAFKN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA