| Definition | Vibrio splendidus LGP32 chromosome 1, complete genome. |
|---|---|
| Accession | NC_011753 |
| Length | 3,299,303 |
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The map label for this gene is spoT [H]
Identifier: 218708222
GI number: 218708222
Start: 153518
End: 155644
Strand: Reverse
Name: spoT [H]
Synonym: VS_0159
Alternate gene names: 218708222
Gene position: 155644-153518 (Counterclockwise)
Preceding gene: 218708223
Following gene: 218708221
Centisome position: 4.72
GC content: 48.52
Gene sequence:
>2127_bases TTGTATCTATTCGATAGCCTCAAAGACGTTGCCCAAGAATACCTAACAGAGCCTCAAGTTGAGGCTCTGCGTCAATCTTA TGTGGTAGCGAGAGACGCCCATGAAGGGCAAACCCGTTCAACGGGTGAACCATACATTATTCACCCTGTAGCTGTTTCAA GAATCCTGGCAGAAATGCGTCTGGATATCGAAACTCTGCAAGCAGCCCTACTCCACGATGTAATTGAAGACACTGAAGTT ACAAAAGAGGAGCTAGAAGCTCAATTCGGCAATACCGTTGCTGAACTGGTTGATGGTGTATCTAAGCTGGATAAGCTTAA ATTTCGTGATCGCAAAGAAGCGCAAGCAGAGAACTTCCGTAAGATGGTTCTCGCGATGGTGCAAGACATCCGCGTTATCT TGATCAAATTAGCTGACCGTACTCACAACATGCGCACGCTTGGGGCACTTCGTCCTGATAAGAAGCGTCGTATTGCTCGT GAAACCCTAGAGATTTATTCTCCGCTAGCTCACCGTCTTGGTATTCATAACATCAAGACCGAGCTAGAAGAGCTGGGCTT CGAAGCCCTTTATCCTAACCGTTATCGCGTCCTGAAAAACGTAGTGAAAGCTGCGCGTGGTAACCGTAAGGAGATGATTC AACGTATCCATAGCGAAATCGAAGGCCGCCTTGAAGAAGTCGGTTTGCCTGCTCGCGTACTTGGTCGTGAAAAGAACCTG TTCTCCATCTATAACAAGATGAAAACCAAAGAACAGCGCTTCCACACCATTATGGACATCTACGCTTTCCGCGTAGTGGT TGATACACCAGATACTTGCTATCGCGTACTTGGTCAGGCCCACAGCCTGTACAAGCCTCGTCCTGGCCGCATGAAAGACT ATATTGCGGTACCGAAAGCCAACGGCTACCAATCTCTGCACACGTCAATGATCGGCCCTCACGGGGTGCCAGTTGAGGTC CAGATCCGTACTGAAGATATGGAGCAGATGGCAGACAAAGGTGTCGCGGCGCACTGGTCTTACAAAGGCAATGGCTCACG CAGTAGCAACGGGACAACCGCACAGGTTAAAGCACAACGTTGGATGCAGAGCTTACTTGAGCTGCAACAAAGCGCAGGTA ACTCATTCGAATTCATTGAAAACGTTAAATCTGATCTGTTCCCAGATGAGATCTTCGTATTCACGCCGAAAGGTCGCATT GTCGAACTTCCAGCAGGCGCAACAGCAGTCGATTTTGCTTACGCGGTACATACCGACGTCGGCAACATGTGTGTCGGTGC TCGTGTAGACATGAACCCTTACCCACTCAGCAAATCGCTGAAGAATGGCCAAACTATTGAGATCATCAGTGCTCCGGGCG CACGTCCGAATGCAGCATGGCTCAACTACGTAGTGACCTCACGTGCGCGTACGAAGATCCGTCAGGTCCTGAAAACGATG CGTCGTGAAGAGTCGATTACCCTTGGCCGTCGCCTACTGAACCATGCACTTGGTGAACACTCTATTGCCGATGTCGGTCA AGAGAATATCGAACATGTATTGTCTGATCTACGTCTCGATAACATTGAAGACTTGCTAGCATCGATTGGTCTTGGTGAAC TGATGAGTATCGTTATTGCTCGTCGTTTATTGGGCGATGCTGACGAACTGACTGAAGTGGCAAACAACAGCGATACGCCT AGGAAGAAATTACCTATCCGTGGTGCTGAAGGCCTATTACTGACGTTCGCTAACTGTTGTCACCCGATTCCAGATGATCA CATTATTGCTCATGTATCTCCAGGTCGTGGTCTCGTGGTACACCGAGAAACGTGTCCAAACGTTCGTGGTTACCAGAAAG AACCGGATAAATACATGGCGGTTGAATGGTCTGACGATTACAACCAAGAGTTCACAGCTGAACTTCAGGTCGAATTGCAG AACCATCAAGGTGCGCTGGCTGAGCTAACTAACGTTATCTCGAAAACAGGCTCGAACATTCACGGTATCTCAACCGAAGA ACGTGACGGACGCTTGTACACAGTGACTATCTTGTTGACCACGAAAGATCGTGTTCATTTAGCGAGCATTATGAAGAAGC TACGTGTGATGCCACACGCGCTCAAAGTAAGACGTCGCAAGAACTAA
Upstream 100 bases:
>100_bases AGAGCAAGAAGCGGCTGAGCTTGCAGCAGTAAGCAGCATCGCTCACACTCGCTGATAGAATCAACGTCATTCGAACTAAT TAACCTTCCGGGCCTTTAAT
Downstream 100 bases:
>100_bases CGTTCGAACTTATTGGCAACTTTGCTAAGAATTGAAATCCCCTTAATGCTTTATCGCTTAAGGGGATTTTTTGTGGCTAC GATTCTAGAGTTCCCCTAGC
Product: bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Products: NA
Alternate protein names: Penta-phosphate guanosine-3'-pyrophosphohydrolase; (ppGpp)ase [H]
Number of amino acids: Translated: 708; Mature: 708
Protein sequence:
>708_residues MYLFDSLKDVAQEYLTEPQVEALRQSYVVARDAHEGQTRSTGEPYIIHPVAVSRILAEMRLDIETLQAALLHDVIEDTEV TKEELEAQFGNTVAELVDGVSKLDKLKFRDRKEAQAENFRKMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIAR ETLEIYSPLAHRLGIHNIKTELEELGFEALYPNRYRVLKNVVKAARGNRKEMIQRIHSEIEGRLEEVGLPARVLGREKNL FSIYNKMKTKEQRFHTIMDIYAFRVVVDTPDTCYRVLGQAHSLYKPRPGRMKDYIAVPKANGYQSLHTSMIGPHGVPVEV QIRTEDMEQMADKGVAAHWSYKGNGSRSSNGTTAQVKAQRWMQSLLELQQSAGNSFEFIENVKSDLFPDEIFVFTPKGRI VELPAGATAVDFAYAVHTDVGNMCVGARVDMNPYPLSKSLKNGQTIEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTM RREESITLGRRLLNHALGEHSIADVGQENIEHVLSDLRLDNIEDLLASIGLGELMSIVIARRLLGDADELTEVANNSDTP RKKLPIRGAEGLLLTFANCCHPIPDDHIIAHVSPGRGLVVHRETCPNVRGYQKEPDKYMAVEWSDDYNQEFTAELQVELQ NHQGALAELTNVISKTGSNIHGISTEERDGRLYTVTILLTTKDRVHLASIMKKLRVMPHALKVRRRKN
Sequences:
>Translated_708_residues MYLFDSLKDVAQEYLTEPQVEALRQSYVVARDAHEGQTRSTGEPYIIHPVAVSRILAEMRLDIETLQAALLHDVIEDTEV TKEELEAQFGNTVAELVDGVSKLDKLKFRDRKEAQAENFRKMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIAR ETLEIYSPLAHRLGIHNIKTELEELGFEALYPNRYRVLKNVVKAARGNRKEMIQRIHSEIEGRLEEVGLPARVLGREKNL FSIYNKMKTKEQRFHTIMDIYAFRVVVDTPDTCYRVLGQAHSLYKPRPGRMKDYIAVPKANGYQSLHTSMIGPHGVPVEV QIRTEDMEQMADKGVAAHWSYKGNGSRSSNGTTAQVKAQRWMQSLLELQQSAGNSFEFIENVKSDLFPDEIFVFTPKGRI VELPAGATAVDFAYAVHTDVGNMCVGARVDMNPYPLSKSLKNGQTIEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTM RREESITLGRRLLNHALGEHSIADVGQENIEHVLSDLRLDNIEDLLASIGLGELMSIVIARRLLGDADELTEVANNSDTP RKKLPIRGAEGLLLTFANCCHPIPDDHIIAHVSPGRGLVVHRETCPNVRGYQKEPDKYMAVEWSDDYNQEFTAELQVELQ NHQGALAELTNVISKTGSNIHGISTEERDGRLYTVTILLTTKDRVHLASIMKKLRVMPHALKVRRRKN >Mature_708_residues MYLFDSLKDVAQEYLTEPQVEALRQSYVVARDAHEGQTRSTGEPYIIHPVAVSRILAEMRLDIETLQAALLHDVIEDTEV TKEELEAQFGNTVAELVDGVSKLDKLKFRDRKEAQAENFRKMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIAR ETLEIYSPLAHRLGIHNIKTELEELGFEALYPNRYRVLKNVVKAARGNRKEMIQRIHSEIEGRLEEVGLPARVLGREKNL FSIYNKMKTKEQRFHTIMDIYAFRVVVDTPDTCYRVLGQAHSLYKPRPGRMKDYIAVPKANGYQSLHTSMIGPHGVPVEV QIRTEDMEQMADKGVAAHWSYKGNGSRSSNGTTAQVKAQRWMQSLLELQQSAGNSFEFIENVKSDLFPDEIFVFTPKGRI VELPAGATAVDFAYAVHTDVGNMCVGARVDMNPYPLSKSLKNGQTIEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTM RREESITLGRRLLNHALGEHSIADVGQENIEHVLSDLRLDNIEDLLASIGLGELMSIVIARRLLGDADELTEVANNSDTP RKKLPIRGAEGLLLTFANCCHPIPDDHIIAHVSPGRGLVVHRETCPNVRGYQKEPDKYMAVEWSDDYNQEFTAELQVELQ NHQGALAELTNVISKTGSNIHGISTEERDGRLYTVTILLTTKDRVHLASIMKKLRVMPHALKVRRRKN
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance [H]
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HD domain [H]
Homologues:
Organism=Homo sapiens, GI38348360, Length=116, Percent_Identity=41.3793103448276, Blast_Score=73, Evalue=1e-12, Organism=Escherichia coli, GI1790082, Length=710, Percent_Identity=71.9718309859155, Blast_Score=1074, Evalue=0.0, Organism=Escherichia coli, GI1789147, Length=731, Percent_Identity=31.0533515731874, Blast_Score=392, Evalue=1e-110, Organism=Caenorhabditis elegans, GI25143118, Length=139, Percent_Identity=36.6906474820144, Blast_Score=73, Evalue=6e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR003607 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =3.1.7.2 [H]
Molecular weight: Translated: 80002; Mature: 80002
Theoretical pI: Translated: 8.60; Mature: 8.60
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYLFDSLKDVAQEYLTEPQVEALRQSYVVARDAHEGQTRSTGEPYIIHPVAVSRILAEMR CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH LDIETLQAALLHDVIEDTEVTKEELEAQFGNTVAELVDGVSKLDKLKFRDRKEAQAENFR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH KMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYSPLAHRLGIHNIKT HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH ELEELGFEALYPNRYRVLKNVVKAARGNRKEMIQRIHSEIEGRLEEVGLPARVLGREKNL HHHHCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHH FSIYNKMKTKEQRFHTIMDIYAFRVVVDTPDTCYRVLGQAHSLYKPRPGRMKDYIAVPKA HHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCC NGYQSLHTSMIGPHGVPVEVQIRTEDMEQMADKGVAAHWSYKGNGSRSSNGTTAQVKAQR CCHHHHHHHHCCCCCCCEEEEECHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHH WMQSLLELQQSAGNSFEFIENVKSDLFPDEIFVFTPKGRIVELPAGATAVDFAYAVHTDV HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCHHHHHHHHHCCC GNMCVGARVDMNPYPLSKSLKNGQTIEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTM CCEEECCEECCCCCCCCHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH RREESITLGRRLLNHALGEHSIADVGQENIEHVLSDLRLDNIEDLLASIGLGELMSIVIA HHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH RRLLGDADELTEVANNSDTPRKKLPIRGAEGLLLTFANCCHPIPDDHIIAHVSPGRGLVV HHHHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEE HRETCPNVRGYQKEPDKYMAVEWSDDYNQEFTAELQVELQNHQGALAELTNVISKTGSNI ECCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCC HGISTEERDGRLYTVTILLTTKDRVHLASIMKKLRVMPHALKVRRRKN CCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHCCC >Mature Secondary Structure MYLFDSLKDVAQEYLTEPQVEALRQSYVVARDAHEGQTRSTGEPYIIHPVAVSRILAEMR CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH LDIETLQAALLHDVIEDTEVTKEELEAQFGNTVAELVDGVSKLDKLKFRDRKEAQAENFR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH KMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYSPLAHRLGIHNIKT HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH ELEELGFEALYPNRYRVLKNVVKAARGNRKEMIQRIHSEIEGRLEEVGLPARVLGREKNL HHHHCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHH FSIYNKMKTKEQRFHTIMDIYAFRVVVDTPDTCYRVLGQAHSLYKPRPGRMKDYIAVPKA HHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCC NGYQSLHTSMIGPHGVPVEVQIRTEDMEQMADKGVAAHWSYKGNGSRSSNGTTAQVKAQR CCHHHHHHHHCCCCCCCEEEEECHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHH WMQSLLELQQSAGNSFEFIENVKSDLFPDEIFVFTPKGRIVELPAGATAVDFAYAVHTDV HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCHHHHHHHHHCCC GNMCVGARVDMNPYPLSKSLKNGQTIEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTM CCEEECCEECCCCCCCCHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH RREESITLGRRLLNHALGEHSIADVGQENIEHVLSDLRLDNIEDLLASIGLGELMSIVIA HHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH RRLLGDADELTEVANNSDTPRKKLPIRGAEGLLLTFANCCHPIPDDHIIAHVSPGRGLVV HHHHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEE HRETCPNVRGYQKEPDKYMAVEWSDDYNQEFTAELQVELQNHQGALAELTNVISKTGSNI ECCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCC HGISTEERDGRLYTVTILLTTKDRVHLASIMKKLRVMPHALKVRRRKN CCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]