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The map label for this gene is ompR [H]

Identifier: 218708219

GI number: 218708219

Start: 148870

End: 149589

Strand: Direct

Name: ompR [H]

Synonym: VS_0156

Alternate gene names: 218708219

Gene position: 148870-149589 (Clockwise)

Preceding gene: 218708216

Following gene: 218708220

Centisome position: 4.51

GC content: 49.31

Gene sequence:

>720_bases
ATGCAAGAAAACTACAAAATTTTAGTGGTCGATGACGATGCTCGTTTACGTGCACTGCTAGAACGCTATCTGTCAGAGCA
AGGCTTTCAAGTGCGTAGCGTGGCAAACAGTGAGCAGATGGACCGCCTGTTAACCCGTGAAAACTTTCACTTGATGGTAT
TGGATTTAATGTTGCCGGGCGAAGACGGTCTTTCGATCTGTCGTCGTCTAAGAAACGCAAACAACTCGCTACCAATCCTG
ATGCTGACCGCAAAGGGTGACGAAGTGGATCGCATTGTGGGTTTGGAAGTGGGTGCTGATGATTACCTGCCAAAACCATT
TAACCCACGTGAACTGCTTGCTCGTATCAAAGCGGTAATGCGTCGCCAAGTGATTGAAGCACCGGGCGCGCCAAGCACAG
AAGAGTCTGTGGTTGAGTTTGGTGAGTTCCGCCTAAACCTAGGTACACGTGAAATGTTCCGCGGTGAAGAGCCTATGCCT
CTTACCTCCGGTGAATTTGCGGTTCTGAAGTCGCTGGTCACTAACGCTCGTGAGCCAATGTCTCGCGATAAGCTGATGAA
CATGGCTCGTGGCCGTGAGTACTCAGCGATGGAACGTTCTATCGATGTCCAGATTTCGCGTTTGCGTCGTCTAGTAGAAG
AAGATCCAAGTAAACCTCGTTATATCCAAACGGTGTGGGGCTTGGGTTATGTATTCGTTCCAGATGGCAAAGCTGTGTAA

Upstream 100 bases:

>100_bases
TTTCCCTCAATAATGTTACATTTTTAATGTCTTATACCAATATACAATGTACCAAGAATGCTTAACCTTAGGTTTAAGCT
TTAATAGGTGGAACCATTAC

Downstream 100 bases:

>100_bases
TCTAGCTTTGCTCGTTCTGTGATTCAGAATTCTTTATTTACGGGTCATCTCATTAATATGTGATGGCCCGTTTTGTATTC
AGCACAATGAGAGATACCAA

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MQENYKILVVDDDARLRALLERYLSEQGFQVRSVANSEQMDRLLTRENFHLMVLDLMLPGEDGLSICRRLRNANNSLPIL
MLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARIKAVMRRQVIEAPGAPSTEESVVEFGEFRLNLGTREMFRGEEPMP
LTSGEFAVLKSLVTNAREPMSRDKLMNMARGREYSAMERSIDVQISRLRRLVEEDPSKPRYIQTVWGLGYVFVPDGKAV

Sequences:

>Translated_239_residues
MQENYKILVVDDDARLRALLERYLSEQGFQVRSVANSEQMDRLLTRENFHLMVLDLMLPGEDGLSICRRLRNANNSLPIL
MLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARIKAVMRRQVIEAPGAPSTEESVVEFGEFRLNLGTREMFRGEEPMP
LTSGEFAVLKSLVTNAREPMSRDKLMNMARGREYSAMERSIDVQISRLRRLVEEDPSKPRYIQTVWGLGYVFVPDGKAV
>Mature_239_residues
MQENYKILVVDDDARLRALLERYLSEQGFQVRSVANSEQMDRLLTRENFHLMVLDLMLPGEDGLSICRRLRNANNSLPIL
MLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARIKAVMRRQVIEAPGAPSTEESVVEFGEFRLNLGTREMFRGEEPMP
LTSGEFAVLKSLVTNAREPMSRDKLMNMARGREYSAMERSIDVQISRLRRLVEEDPSKPRYIQTVWGLGYVFVPDGKAV

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=84.7457627118644, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.9912663755458, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=36.9098712446352, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=35.1931330472103, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=34.1880341880342, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=33.1896551724138, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=37.8260869565217, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=38.034188034188, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=35.1694915254237, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=35.2422907488987, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=33.7719298245614, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=33.7662337662338, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=33.4801762114537, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=33.4801762114537, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.8943089430894, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27275; Mature: 27275

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQENYKILVVDDDARLRALLERYLSEQGFQVRSVANSEQMDRLLTRENFHLMVLDLMLPG
CCCCCEEEEECCCHHHHHHHHHHHHHCCCEEHHHCCHHHHHHHHHHCCCEEEEEEEECCC
EDGLSICRRLRNANNSLPILMLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARIKAVM
CHHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRQVIEAPGAPSTEESVVEFGEFRLNLGTREMFRGEEPMPLTSGEFAVLKSLVTNAREPM
HHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCH
SRDKLMNMARGREYSAMERSIDVQISRLRRLVEEDPSKPRYIQTVWGLGYVFVPDGKAV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MQENYKILVVDDDARLRALLERYLSEQGFQVRSVANSEQMDRLLTRENFHLMVLDLMLPG
CCCCCEEEEECCCHHHHHHHHHHHHHCCCEEHHHCCHHHHHHHHHHCCCEEEEEEEECCC
EDGLSICRRLRNANNSLPILMLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARIKAVM
CHHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRQVIEAPGAPSTEESVVEFGEFRLNLGTREMFRGEEPMPLTSGEFAVLKSLVTNAREPM
HHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCH
SRDKLMNMARGREYSAMERSIDVQISRLRRLVEEDPSKPRYIQTVWGLGYVFVPDGKAV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]