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The map label for this gene is epsL [H]

Identifier: 218708207

GI number: 218708207

Start: 137422

End: 138669

Strand: Direct

Name: epsL [H]

Synonym: VS_0143

Alternate gene names: 218708207

Gene position: 137422-138669 (Clockwise)

Preceding gene: 218708206

Following gene: 218708208

Centisome position: 4.17

GC content: 46.39

Gene sequence:

>1248_bases
GTGAGCGAGTTTCTGACCGTTCGACTGAGTAGCGAGCCACAAAGCCCAGTGCAGTGGTTGGTTTGGTCGACAAGCCAACA
AGAAGTGATAGCAAGTGGTGAGCTGTCTAGCTGGGATCAGCTTGATGAGTTAACGCCTTACGCTGAAAAGCGTAGCTGTA
TCGCTTTATTGCCGGGAAATGAGTGCTTAATTAAGCGTGTTGAAATTCCGAAAGGTGCTGCTCGCCAGTTCGACTCTATG
CTGCCATTTTTGTTAGAAGACGAAGTGGCACAAGATATCGAAGACTTACATCTAACCATTTTAGATAAAGACGCAACGCA
CGCTACTGTGTGTGGTGTAGATCGCGAATGGTTAAAACAAGCTTTAGACCAGTTTCGCAAAGCCAATATTATTTTCCGTA
AGGTGCTGCCAGATACACTAGCCGTGCCTGTTGAAGAGCAAGGCATCAGTGCGTTGCAAATCGACCAGCATTGGCTATTG
CGCCAAGGTCACTCTCAACGTCAAGGTCATTATCAAGCGGTATCGATCAGCGAAGCATGGTTACCGATGTTTTTGCAAAG
TGATTGGGTTGTAGCTGACGACGAAGAACAACCTACGACTATCTTCAGCTACACCACAATGCCGAGCGATGATGTACAGC
AGCAAAGCGGTATGGAATGGCAAGCAAAGCCTGCGGAATTGGTGATGTCCTTATTGAGCCAACAAGCGATCACAAGCGGC
GTAAATTTACTGACTGGCACCTTTAAAACCAAATCTTCTTTCAGTAAATATTGGCGTGTATGGCAGAAGGTGGCGATTGC
TGCTTGCTTGCTGGTGGCCGTGATTGTGACTCAACAAGTGTTGAAGGTGCAGCAATACGAAGCACAGGCACAAGCCTATC
GCATGGAGAGTGAGCGTATCTTTAGAGCCGTTCTGCCAGGCAAACAACGAATTCCTACAGTAAGCTACCTTAAGCGTCAG
ATGAATGATGAAGCTAAGAAATACGGTGGCTCAGGCGATGGTGACTCCTTACTTGGTTGGTTAGCATTGCTGCCAGAAAC
GTTAGGACAAGTGAAATCGATCGAAGTCGAAAGCATTCGCTATGATGGCAATCGTTCTGAAGTTCGATTACAAGCTAAAA
GCGCTGATTTTCAACATTTTGAGACGGCTAAAGTAAAACTTGAAGAGAAGTTTTCCGTTGAACAAGGGCCATTGAACCGT
AATGGCGATGCCGTATTTGGCAGTTTTACCCTTAAACCCCGTCAGTAA

Upstream 100 bases:

>100_bases
GAGGTATTAGTTGAGCAGTCTCGTGTACGTATACGAACGCTTTTCTATAGTAGTAATAGAGAAACAGTGACGGTAGTACG
CCGTCGTTTTGGAGGAATCC

Downstream 100 bases:

>100_bases
CTGCGCAAGGAGATCAGTGATGAGAAATATAATTGAACCACTCCAAGCGTGGTGGACTTCAATAAGTCAAAGAGAGCAAC
GATTAGTCGTTGGTTGCTCA

Product: type II secretory pathway subunit EpsL

Products: NA

Alternate protein names: Cholera toxin secretion protein epsL [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSEFLTVRLSSEPQSPVQWLVWSTSQQEVIASGELSSWDQLDELTPYAEKRSCIALLPGNECLIKRVEIPKGAARQFDSM
LPFLLEDEVAQDIEDLHLTILDKDATHATVCGVDREWLKQALDQFRKANIIFRKVLPDTLAVPVEEQGISALQIDQHWLL
RQGHSQRQGHYQAVSISEAWLPMFLQSDWVVADDEEQPTTIFSYTTMPSDDVQQQSGMEWQAKPAELVMSLLSQQAITSG
VNLLTGTFKTKSSFSKYWRVWQKVAIAACLLVAVIVTQQVLKVQQYEAQAQAYRMESERIFRAVLPGKQRIPTVSYLKRQ
MNDEAKKYGGSGDGDSLLGWLALLPETLGQVKSIEVESIRYDGNRSEVRLQAKSADFQHFETAKVKLEEKFSVEQGPLNR
NGDAVFGSFTLKPRQ

Sequences:

>Translated_415_residues
MSEFLTVRLSSEPQSPVQWLVWSTSQQEVIASGELSSWDQLDELTPYAEKRSCIALLPGNECLIKRVEIPKGAARQFDSM
LPFLLEDEVAQDIEDLHLTILDKDATHATVCGVDREWLKQALDQFRKANIIFRKVLPDTLAVPVEEQGISALQIDQHWLL
RQGHSQRQGHYQAVSISEAWLPMFLQSDWVVADDEEQPTTIFSYTTMPSDDVQQQSGMEWQAKPAELVMSLLSQQAITSG
VNLLTGTFKTKSSFSKYWRVWQKVAIAACLLVAVIVTQQVLKVQQYEAQAQAYRMESERIFRAVLPGKQRIPTVSYLKRQ
MNDEAKKYGGSGDGDSLLGWLALLPETLGQVKSIEVESIRYDGNRSEVRLQAKSADFQHFETAKVKLEEKFSVEQGPLNR
NGDAVFGSFTLKPRQ
>Mature_414_residues
SEFLTVRLSSEPQSPVQWLVWSTSQQEVIASGELSSWDQLDELTPYAEKRSCIALLPGNECLIKRVEIPKGAARQFDSML
PFLLEDEVAQDIEDLHLTILDKDATHATVCGVDREWLKQALDQFRKANIIFRKVLPDTLAVPVEEQGISALQIDQHWLLR
QGHSQRQGHYQAVSISEAWLPMFLQSDWVVADDEEQPTTIFSYTTMPSDDVQQQSGMEWQAKPAELVMSLLSQQAITSGV
NLLTGTFKTKSSFSKYWRVWQKVAIAACLLVAVIVTQQVLKVQQYEAQAQAYRMESERIFRAVLPGKQRIPTVSYLKRQM
NDEAKKYGGSGDGDSLLGWLALLPETLGQVKSIEVESIRYDGNRSEVRLQAKSADFQHFETAKVKLEEKFSVEQGPLNRN
GDAVFGSFTLKPRQ

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG3297

COG function: function code U; Type II secretory pathway, component PulL

Gene ontology:

Cell location: Cell inner membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP L family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007812 [H]

Pfam domain/function: PF05134 GspL [H]

EC number: NA

Molecular weight: Translated: 46912; Mature: 46781

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFLTVRLSSEPQSPVQWLVWSTSQQEVIASGELSSWDQLDELTPYAEKRSCIALLPGN
CCCEEEEEECCCCCCCCEEEEECCCCHHHEECCCCCCHHHHHHCCCCCCCCCEEEEECCC
ECLIKRVEIPKGAARQFDSMLPFLLEDEVAQDIEDLHLTILDKDATHATVCGVDREWLKQ
CEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCEEEEEECCCCCEEEECCCHHHHHH
ALDQFRKANIIFRKVLPDTLAVPVEEQGISALQIDQHWLLRQGHSQRQGHYQAVSISEAW
HHHHHHHHHHHHHHHCCHHHCCCCHHCCCCEEEEHHHHHHHCCCCCCCCCEEEEEECHHH
LPMFLQSDWVVADDEEQPTTIFSYTTMPSDDVQQQSGMEWQAKPAELVMSLLSQQAITSG
HHHHHCCCEEEECCCCCCCEEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
VNLLTGTFKTKSSFSKYWRVWQKVAIAACLLVAVIVTQQVLKVQQYEAQAQAYRMESERI
CHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRAVLPGKQRIPTVSYLKRQMNDEAKKYGGSGDGDSLLGWLALLPETLGQVKSIEVESIR
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEE
YDGNRSEVRLQAKSADFQHFETAKVKLEEKFSVEQGPLNRNGDAVFGSFTLKPRQ
ECCCCCEEEEEECCCCCHHHHHHHEEEHHHHCCCCCCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
SEFLTVRLSSEPQSPVQWLVWSTSQQEVIASGELSSWDQLDELTPYAEKRSCIALLPGN
CCEEEEEECCCCCCCCEEEEECCCCHHHEECCCCCCHHHHHHCCCCCCCCCEEEEECCC
ECLIKRVEIPKGAARQFDSMLPFLLEDEVAQDIEDLHLTILDKDATHATVCGVDREWLKQ
CEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCEEEEEECCCCCEEEECCCHHHHHH
ALDQFRKANIIFRKVLPDTLAVPVEEQGISALQIDQHWLLRQGHSQRQGHYQAVSISEAW
HHHHHHHHHHHHHHHCCHHHCCCCHHCCCCEEEEHHHHHHHCCCCCCCCCEEEEEECHHH
LPMFLQSDWVVADDEEQPTTIFSYTTMPSDDVQQQSGMEWQAKPAELVMSLLSQQAITSG
HHHHHCCCEEEECCCCCCCEEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
VNLLTGTFKTKSSFSKYWRVWQKVAIAACLLVAVIVTQQVLKVQQYEAQAQAYRMESERI
CHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRAVLPGKQRIPTVSYLKRQMNDEAKKYGGSGDGDSLLGWLALLPETLGQVKSIEVESIR
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEE
YDGNRSEVRLQAKSADFQHFETAKVKLEEKFSVEQGPLNRNGDAVFGSFTLKPRQ
ECCCCCEEEEEECCCCCHHHHHHHEEEHHHHCCCCCCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]