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The map label for this gene is uspA [H]

Identifier: 218708156

GI number: 218708156

Start: 84340

End: 84795

Strand: Reverse

Name: uspA [H]

Synonym: VS_0090

Alternate gene names: 218708156

Gene position: 84795-84340 (Counterclockwise)

Preceding gene: 218708159

Following gene: 218708155

Centisome position: 2.57

GC content: 43.42

Gene sequence:

>456_bases
ATGAATAGAAGAGGTAGCGATATGAGTTACAAACATATTTTGGTCGCAGTCGATTTATCAGATGACAGCAAATTACTTGT
GGATAAAGCGGTAGCATTGGCTAAGCCATTGGAAGCCAAAGTCTCTTTTATCCATATCGATATTAATTATGCAGAGCTCT
ATACCGGCCTTATTGATATCAACATGGCAGAAACCCAGCACAACGCGATGGAAGCATCTCGAGTTCAGCTACAAAATTTT
GCAGAACACGCTCAATACCCGATTACCCACACCTTAGTGGGCAGCGGCGACCTGAGTCATGAACTGTGTGACACCATCAA
TGAATTCAATGTTGATTTAGTGGTTTGTGGGCACCATCAAGACTTCTGGAGCAAATTGCTCTCTTCAACACGACAACTGA
TCAATGCCTCGCCGGTTGATATGCTGGTCGTGCCTCTAAGAGATTCAGAAGACTAA

Upstream 100 bases:

>100_bases
TTAGTTAACCAATATTTCGAGCAAACATTACGCAAGACAGTGGATATGAGATCACTTCAGCAAAAAAAGGGATTGCATAG
TGCTAGTCTTTAGTTAGGCA

Downstream 100 bases:

>100_bases
TGAATTAAGGTTAGGTAACATACAGCTCATATCTTATTAACGAAGTTTTTATATGAGCTATTTAGCTAGTGTTACCCTCT
TATGGGCCTTCTCTTTTAGC

Product: universal stress protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNRRGSDMSYKHILVAVDLSDDSKLLVDKAVALAKPLEAKVSFIHIDINYAELYTGLIDINMAETQHNAMEASRVQLQNF
AEHAQYPITHTLVGSGDLSHELCDTINEFNVDLVVCGHHQDFWSKLLSSTRQLINASPVDMLVVPLRDSED

Sequences:

>Translated_151_residues
MNRRGSDMSYKHILVAVDLSDDSKLLVDKAVALAKPLEAKVSFIHIDINYAELYTGLIDINMAETQHNAMEASRVQLQNF
AEHAQYPITHTLVGSGDLSHELCDTINEFNVDLVVCGHHQDFWSKLLSSTRQLINASPVDMLVVPLRDSED
>Mature_151_residues
MNRRGSDMSYKHILVAVDLSDDSKLLVDKAVALAKPLEAKVSFIHIDINYAELYTGLIDINMAETQHNAMEASRVQLQNF
AEHAQYPITHTLVGSGDLSHELCDTINEFNVDLVVCGHHQDFWSKLLSSTRQLINASPVDMLVVPLRDSED

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=144, Percent_Identity=60.4166666666667, Blast_Score=188, Evalue=1e-49,
Organism=Escherichia coli, GI1790358, Length=142, Percent_Identity=33.0985915492958, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1788205, Length=140, Percent_Identity=32.8571428571429, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 16890; Mature: 16890

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRGSDMSYKHILVAVDLSDDSKLLVDKAVALAKPLEAKVSFIHIDINYAELYTGLIDI
CCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHEE
NMAETQHNAMEASRVQLQNFAEHAQYPITHTLVGSGDLSHELCDTINEFNVDLVVCGHHQ
EECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEECCCH
DFWSKLLSSTRQLINASPVDMLVVPLRDSED
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MNRRGSDMSYKHILVAVDLSDDSKLLVDKAVALAKPLEAKVSFIHIDINYAELYTGLIDI
CCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHEE
NMAETQHNAMEASRVQLQNFAEHAQYPITHTLVGSGDLSHELCDTINEFNVDLVVCGHHQ
EECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEECCCH
DFWSKLLSSTRQLINASPVDMLVVPLRDSED
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]